00:55 = What is cancer? 01:44 = Characteristics of benign tumours 03:12 = Characteristics of malignant tumours 04:29 = Oncogene action/regulation 05:29 = Tumour suppressor gene action/regulation 07:01 = How increased concentrations of oestrogen can increase breast cancer risk 08:19 = Exam questions and mark schemes
It mentions in my textbook that the oestrogen releases an inhibitor molecule that prevents transcription causing proto-oncogenes of breast tissue to develop into oncogenes and these oncogenes increase the rate of cell division. Please could you explain this?
So on oncogenes it says that it leads to increased expression as chromatin is less condensed but on tumour suppressor genes it says it will lead to increased expression as chromatin is more condensed? Aren’t they contradicting one another?
Hi! So in the video, I didn't mean that the TSG gene is more expressed , I meant that more tumours are expressed because the expression of the tumour suppressor gene (which normally limits tumour formation) is reduced. Hope this makes sense! :)
@@AlevelBiologyHelp so would it be right to say that hypermethylation decreases expression of tumour suppressor genes, which leads to an increased expressions of tumours?
Hi, is all this information enough for me to do exam questions based on gene expression. As well as, are the definitions AQA based or did you make it yourself>
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00:55 = What is cancer?
01:44 = Characteristics of benign tumours
03:12 = Characteristics of malignant tumours
04:29 = Oncogene action/regulation
05:29 = Tumour suppressor gene action/regulation
07:01 = How increased concentrations of oestrogen can increase breast cancer risk
08:19 = Exam questions and mark schemes
Thank you so much for your help - your style of videos are really helpful!
Thank you so much for this video, it was really helpful !
It mentions in my textbook that the oestrogen releases an inhibitor molecule that prevents transcription causing proto-oncogenes of breast tissue to develop into oncogenes and these oncogenes increase the rate of cell division. Please could you explain this?
So on oncogenes it says that it leads to increased expression as chromatin is less condensed but on tumour suppressor genes it says it will lead to increased expression as chromatin is more condensed? Aren’t they contradicting one another?
Hi! So in the video, I didn't mean that the TSG gene is more expressed , I meant that more tumours are expressed because the expression of the tumour suppressor gene (which normally limits tumour formation) is reduced. Hope this makes sense! :)
@@AlevelBiologyHelp so would it be right to say that hypermethylation decreases expression of tumour suppressor genes, which leads to an increased expressions of tumours?
@@Mozzie7920 It would probably be better to just say it leads to a higher tumour formation :)
@@AlevelBiologyHelp okay thanks for the help
when would you use a line graph?
Line graphs would be used to track a change in something over a period of time. :)
Hi, is all this information enough for me to do exam questions based on gene expression. As well as, are the definitions AQA based or did you make it yourself>
Yes, this is all the information you'll need and the definitions are based on the AQA specification so they will be accepted in an exam!
Thank you
class.