I love how people think parabens are dangerous, but botox is just fine. I have unfollowed any of the creators that pushes "clean beauty", but gets botox. I do like when argireline is in a product, but I'm certainly not going to go out of my way for it. Many blessings!!!💖💖💖
As a neurobiology student I appreciate this video SO much!!! Thank you for clearing up the confusion on this topic in such a informative and clear way!!!!
Before the Ordinary was created, I was using Peter Thomas Roth's Peptide toner and before that, something else with argireline. After 10 or so years, I can say that my forehead doesn't move like it did when I was younger and the elevens I had had, are gone. So, maybe🤷, but I use lots of stuff so no way to know for sure. However, I suffer from hyperhydrosis and Botox is a treatment. My skin hates aluminum antiperspirants and I get horrible acne so when I read about argireline, I started putting the PTR under my arms. It seemed to work and then it was discontinued. That is when the Ordinary made it's appearance. I've been using the Ordinary's argireline serum under my arms ever since and my sweat is now normal on my hands and underarms. I don't use it on my feet and so nothing has changed with them, still so sweaty that I have fallen from sliding inside my shoes🤣. I swear by the stuff. Do I still sweat, yes, do I have to change every couple hours because my clothes are uncomfortable, no. It took at least a year of constant use and I do still sweat and make expressions, just much less.
Oh wow, that’s so interesting to hear! I was aware of Botox used as a treatment for sweating, but I didn’t think of argireline for it. Thanks for sharing! I also thought PTR had something similar before, so I was so surprised this was “new”. Must be a reformulation/update?
Im so excited that you did this! I was getting botox for migraines and liked how it softened my wrinkles but for the last 3 years ive had cyclic treatment resistant anxiety and depression and after tracking found out it was from botox!! Its even listed as a side effect in their literature. So i am happy to see that i might still be able to get anti wrinkle effects without poisoning myself anymore ❤
This was so interesting, thank you for breaking it down because i really didnt understood where "botox in a bottle" even came from. I also have a needle phobia, ive gotten to the point where i dont pass out, i only cry and shake and need to lay down while getting blood drawn. Its nice to hear that another adult has my same fear after being told so many times it's a childrens phobia 😭
I see our brains are wired similarly there. I shut down, which always feels a blend of embarrassing, surprising, and exceedingly out of character. I cannot speak at all 😔 Thankfully, Ara is a *hero* who goes with me and explains the situation to the nurses. They’ve all been so kind once it’s explained, even though I can’t verbally thank them. I can say that every one of them has said I’m not alone (along with encouraging words). Perhaps there are dozens of us!
Argireline works for me. I have been using The Ordinary for years. It seems to have lessened my "11" lines over the 5 years I hve been using it. They are not completely gone, but I will keep using it for the results I've gotten since it is so affordable.
Thank you for sharing! Yep, I love that the price point is great and the ordinary created a formula that is exactly as recommended by the peptide manufacturer!
I honestly don't get why so many people emphasize over and over that Argireline isn't Botox. No shade to you, I'm just baffled that so many people are saying that (I've been recommend countless videos by RUclips). I always understood "Botox in a bottle" as a metaphor. It's like saying "I died laughing", it doesn't mean that I actually died and nobody in their right mind would interpret it that way. It's just meant to express that I was laughing so hard that I almost couldn't breathe and felt like I was dying in an exaggerated way. The same goes for Botox in a bottle, it's not actually Botox because only Botox is Botox. This is Argireline but there are certain similarities that make you feel it could be Botox, but of course not completely. But who knows, maybe it's just me who saw it that way 😂
I think a lot of us see it that way, but…a lot of people don’t! I read a story on the Ulta subreddit of a customer who was very unhappy that TO’s serum didn’t completely inhibit muscle movement. Part of me really wonders if that one is on short form videos that do a poor job of explaining it, ugh (I hesitate to fully blame influencers as the short form is another part of the issue imo - multi-faceted, if you will!)
@@AliceintheRabbitHole yeah it makes sense. I haven't witnessed it myself but I can see why you made a video explaining how Botox and Argireline actually work, for those who may not be aware 😊 it was a very good video btw.
Just because you understand that "botox in a bottle" is just a metaphor that doesn't mean that others too. Spread that metaphor to a bunch of pre-teens in social media (like tiktok) and see it spread like a wildfire. Look at what happened with the misinformation about Bachuchiol...
@@user-hc2dz5cw9t Children/teens are going to do dangerous things even if adults try to make them aware of dangers. Sometimes, they do it BECAUSE adults try to discourage them. It's unfortunately human nature. Look at the tide pods epidemic a few years back. Nobody claimed that tide pods are super yummy candy, yet they still came up with it.
For me, the ordinary argireline is a HG and I will never be without it. I have never thought it was "botox in a bottle", nor are the effects going to be permanent, they aren't with botox, either. I have used many peptide containing products, and none have smoothed the lines on my forehead, smile lines, lines around my lips, and hooded lids like argireline. How do I know it is the argireline? Because I have done extended travel for months without it and can see a difference, and I travel with other peptide serums. I personally like the liquid texture because I can put it on and it absorbs quickly so that I can move on to the next serum/essence.
Alice, I have never seen any benefit from algerine. Thank you for explaining this mechanism of action so well. I think it's just placebo. I hope you are well and have a good week 🌷
Thank you for explaining this!! Imo at least Argereline makes theoretical sense unlike some of the things I’ve seen advertised as alternatives for Botox or vitamin A … people get real …creative 😂 I did know at least Argereline was different but I really never understood how or why. I also didn’t realize it was in the multi peptide serum that really is a good serum!!
EXACTLY!! There’s a reason behind the nickname, but…it’s still less “proven” than Lipotec would like to admit Sometimes I think about how brands that market to us are also marketed to in their own way by ingredient suppliers 🤔
I’ve seen bakuchiol be labeled as a retinol alternative, and then a Botox alternative, and just can’t fathom how anyone could think these claims are true 😅.
@@AliceintheRabbitHole They are. Ingredient manufacturers have sales reps, and purposefully display certain info on their websites and catalogs, but at the end of the day it’s on the brand to do their own research, and hire people who are knowledgeable in ingredients and formulations.
Placebo effect is why I’m always skeptical of new skincare claims. Argireline sounds promising, but based on the results that I’ve heard people say they’ve gotten it sounds no different than the results I’ve gotten from using other peptides. I’m not a fan of TO , so it’s a pass for me, but argireline in general looks promising, and I look forward to seeing what science and users are saying about it in a couple years from now.
I feel like I was just in class lol! Thank you for the great explanation including illustrations, just what I needed to really get what you were saying. Really interesting discussion, thank you!
I. LOVE that you are a research scientist! I learn so much from you! I have used TO Argiriline for way too long, to have not seen any results. :( 😢. I am almost 80 and been into “anti-aging “ skincare for only about 4 years (well, since the lockdown, and I got bored and tuned into too many you tubes-lol). I wonder if I am too old to see many results from any anti-aging products? I do have good skin, have always taken care of it, but never even heard the words “retinol or tretinoin”, until lockdown! I quilted, cross stitched, punch needled, all crafts, but was never tied to the internet…like now! 😂. Could I be spending my retirement income unwisely? 🤦🏼♀️ 🤷🏼
Thank you for this deep-dive, Alice! So interesting. For me, even if Argireline DOES have a minor effect, it isn't changing the structure of the skin in any way, so it's just smoke and mirrors. I guess that's no different from makeup (which I don't wear), but I just want my skincare to be making long-term improvements: not just pretending it is. One could argue that Argireline, if it works and if you use it until the end of time, could ultimately inhibit static wrinkles, but that just seems like a lot of effort for no guaranteed payoff. I'm certainly not devoting a whole serum/step in my routine to it, and I've outgrown The Ordinary in general. They can keep their horde of "+HA" serums (as if that's somehow still a marketing point?). Finally, most of us discussing this topic use a metric excrement-ton of skincare. It would seem that unless you are isolating over a long period of time, it's nigh impossible to know if it's the Argireline or the gestalt of everything being used.
I think about that last point a lot, and it’s why these days I kind of gravitate away from any kind of personal claims. I’ve said it before and will say it again: all of us skincare enthusiasts would be excluded from a research trial 🤣
It 100% works, imo, on my forehead. I used to furrow my eyebrows so easily every time i even squinted. Now it's much more difficult to make that face. My elevens have faded significantly
Thank you for making the mechanism of Botox and acetyl hexapeptide-8 more understandable. I have dry, mature skin. I used TO’s Argireline around and between my eyes. Between my eyes are little frown lines😠, I did notice that they weren’t not as deep while using acetyl hexapeptide-8, nor can I make those lines as easily. I now use products containing acetyl hexapeptide-8, but I didn’t get a new bottle of TO’s Argireline during the November sale. I appear to have kept some of my results, but not all. I think it worked better in TO’s product because it is likely more concentrated.
It’s something I really respect about the ordinary: they tell us concentrations! And yep, 3-10% (of the 0.05% solution) is the recommended use level, so the ordinary is on the higher end with Lipotec’s suggestions!
I have been using matrixyl and argireline combo for years now and Buffett now multi-peptide + ha at night every day I think it helps slow the process and I saw a difference after 3 months. I am 58
Now I can't say anything long term but i got this Ordinary solution a couple days ago. I am using as a potential inhibitor for 11 lines and I also use this on my top lip to try to prevent mouth lines as well. I do notice inhibition, especially on my forehead. What I would be interested to know if this will eventually decrease in potency as the skin gets used to it. I sincerely hope not as I think this product so far is an excellent and cheap addition to a skincare routine
Thank you! It’s such an interesting topic imo, and Lipotec is very convinced on their peptide (they even claim proof of the mechanism via catecholamine release but…I find it a bit, let’s say optimistic lol)
I have the ordinary multi peptide plus copper serum and try to use it on the days I don’t use vitamin c serum which means I don’t use it often. Think some have debunked using vitamin c and copper together but even so, I don’t like applying multiple products in the morning. Serum, sometimes moisturizer and always sunscreen is all I can handle. I didn’t realize ordinary multi peptide serum has argireline. Wonder what the precentage is compared to stand alone argireline. Great point about thinner skin being more receptive to argireline Alice!
Thx Alice fir the video . I have been using TO Argireline for a few years . I guess it does make difference as far as topical goes . May I suggest you to try the Haruharu 5 Peptide Concentrate Cream which I believed include argireline . I am on it for 1 week hoping it will reinforce the strength of argireline . Love to hear your opinion . ☺️
Anyone know why the ordinary or Argireline solution made my forehead have so many fine lines and incredible sagging it's the only product I introduced different into my skin care and it was very harsh dried me out very badly caused severe sagging and I can't reverse it so far and I don't understand and yes I used good moisturizers on top of it so wondering if this happened to anyone else!!!!
The copper peptides by the ordinary are wayyyy better and have argireline in it! I will still get Botox but it has saved me during pregnancy AND makes Botox last longer for me. Also get the off brand botoxes like Jeaveau, last longer for me and are cheaper!
Thank you for the sciencey breakdown! Curious who first thought "let me inject myself with this deadly poison and see what happens" - maybe trying to self-embalm?
If you want the answer, I did come across it! I think links don’t work on RUclips anymore so I’ll share the citation instead: Scott AB, Honeychurch D, Brin MF. Early development history of Botox (onabotulinumtoxinA). Medicine (Baltimore). 2023 Jul 1;102(S1):e32371. doi: 10.1097/MD.0000000000032371. PMID: 37499077; PMCID: PMC10374179.
Hey Alice, given the topic today- I was wondering if you've ever heard of/uses the Snoxin II serum from Indeed Labs? Obviously it's not Botox in any way, but as a serum it reminds me of the Matrixyl & Arginine (sp?) combo. In fact it contains some of those ingredients. Anyway, if you ever get a chance I'd love to hear a review or just what your thoughts on this serum are. ETA: I do own a tube of it byt I've only just recently started using it. And I dont tend to *love* when serums have dimethicone high up ik the ingredients because of layering and pilling issues. (Love silicones in a moisturizer or in hair conditioner, though! lol)
Thank you for talking about the placebo effect! I am always thinking about it in the back of my mind. Did this really work or did I just will it to? My mom is a chemist, I blame her for that one. 😂
I wonder if the Medicube age-r booster would help with penetration and effectiveness? I’m thinking about trying it that way to see if it helps Botox last a little longer. I am using it now to help my brow look more lifted as they’re pretty heavy naturally. I’m not expecting miracles by any stretch of the imagination. I’ve also become a little obsessed with the Age-R booster. I totally thought it was a gimmick but my products all work so much better now.
Okay, I’m only five minutes in, but I had to say…. I just opened up the RUclips app to continue watching some thing I was watching earlier and your video was at the top of my notifications. I said “oh I’m about to place a stylevanna order, let me go see what she needs me to add to my cart.” 😅😅 Then I hear the topic, and think “oh, no, I just need to be reminded to make my Botox appointment .”😅
I get more concentrated Arg. from a site for diy cosmetics. Not cheap at all! I put a single drop in my AM toner on my palm and the effects have been slight but noticeable. TO did nothing to me. I don't even know the concentration of my mixture, but some how it works.
I love how people think parabens are dangerous, but botox is just fine. I have unfollowed any of the creators that pushes "clean beauty", but gets botox.
I do like when argireline is in a product, but I'm certainly not going to go out of my way for it.
Many blessings!!!💖💖💖
🥰🥰
As a neurobiology student I appreciate this video SO much!!! Thank you for clearing up the confusion on this topic in such a informative and clear way!!!!
Glad it was helpful! ☺️
Before the Ordinary was created, I was using Peter Thomas Roth's Peptide toner and before that, something else with argireline. After 10 or so years, I can say that my forehead doesn't move like it did when I was younger and the elevens I had had, are gone. So, maybe🤷, but I use lots of stuff so no way to know for sure. However, I suffer from hyperhydrosis and Botox is a treatment. My skin hates aluminum antiperspirants and I get horrible acne so when I read about argireline, I started putting the PTR under my arms. It seemed to work and then it was discontinued. That is when the Ordinary made it's appearance. I've been using the Ordinary's argireline serum under my arms ever since and my sweat is now normal on my hands and underarms. I don't use it on my feet and so nothing has changed with them, still so sweaty that I have fallen from sliding inside my shoes🤣. I swear by the stuff. Do I still sweat, yes, do I have to change every couple hours because my clothes are uncomfortable, no. It took at least a year of constant use and I do still sweat and make expressions, just much less.
Oh wow, that’s so interesting to hear! I was aware of Botox used as a treatment for sweating, but I didn’t think of argireline for it. Thanks for sharing!
I also thought PTR had something similar before, so I was so surprised this was “new”. Must be a reformulation/update?
Wow so do u put on in place of deodorant? Thanks for sharing
Im so excited that you did this! I was getting botox for migraines and liked how it softened my wrinkles but for the last 3 years ive had cyclic treatment resistant anxiety and depression and after tracking found out it was from botox!! Its even listed as a side effect in their literature. So i am happy to see that i might still be able to get anti wrinkle effects without poisoning myself anymore ❤
I always appreciate your down to earth honesty and ability to give us the facts in accessible language.
Thank you for the kind words ☺️
YES!!!!!
This was so interesting, thank you for breaking it down because i really didnt understood where "botox in a bottle" even came from. I also have a needle phobia, ive gotten to the point where i dont pass out, i only cry and shake and need to lay down while getting blood drawn. Its nice to hear that another adult has my same fear after being told so many times it's a childrens phobia 😭
I see our brains are wired similarly there. I shut down, which always feels a blend of embarrassing, surprising, and exceedingly out of character. I cannot speak at all 😔 Thankfully, Ara is a *hero* who goes with me and explains the situation to the nurses. They’ve all been so kind once it’s explained, even though I can’t verbally thank them. I can say that every one of them has said I’m not alone (along with encouraging words). Perhaps there are dozens of us!
Argireline works for me. I have been using The Ordinary for years. It seems to have lessened my "11" lines over the 5 years I hve been using it. They are not completely gone, but I will keep using it for the results I've gotten since it is so affordable.
Thank you for sharing! Yep, I love that the price point is great and the ordinary created a formula that is exactly as recommended by the peptide manufacturer!
Do you use it all over your whole face?
I honestly don't get why so many people emphasize over and over that Argireline isn't Botox. No shade to you, I'm just baffled that so many people are saying that (I've been recommend countless videos by RUclips). I always understood "Botox in a bottle" as a metaphor. It's like saying "I died laughing", it doesn't mean that I actually died and nobody in their right mind would interpret it that way. It's just meant to express that I was laughing so hard that I almost couldn't breathe and felt like I was dying in an exaggerated way. The same goes for Botox in a bottle, it's not actually Botox because only Botox is Botox. This is Argireline but there are certain similarities that make you feel it could be Botox, but of course not completely. But who knows, maybe it's just me who saw it that way 😂
I think a lot of us see it that way, but…a lot of people don’t! I read a story on the Ulta subreddit of a customer who was very unhappy that TO’s serum didn’t completely inhibit muscle movement. Part of me really wonders if that one is on short form videos that do a poor job of explaining it, ugh (I hesitate to fully blame influencers as the short form is another part of the issue imo - multi-faceted, if you will!)
@@AliceintheRabbitHole yeah it makes sense. I haven't witnessed it myself but I can see why you made a video explaining how Botox and Argireline actually work, for those who may not be aware 😊 it was a very good video btw.
Just because you understand that "botox in a bottle" is just a metaphor that doesn't mean that others too. Spread that metaphor to a bunch of pre-teens in social media (like tiktok) and see it spread like a wildfire. Look at what happened with the misinformation about Bachuchiol...
@@user-hc2dz5cw9t Children/teens are going to do dangerous things even if adults try to make them aware of dangers. Sometimes, they do it BECAUSE adults try to discourage them. It's unfortunately human nature. Look at the tide pods epidemic a few years back. Nobody claimed that tide pods are super yummy candy, yet they still came up with it.
For me, the ordinary argireline is a HG and I will never be without it. I have never thought it was "botox in a bottle", nor are the effects going to be permanent, they aren't with botox, either. I have used many peptide containing products, and none have smoothed the lines on my forehead, smile lines, lines around my lips, and hooded lids like argireline. How do I know it is the argireline? Because I have done extended travel for months without it and can see a difference, and I travel with other peptide serums. I personally like the liquid texture because I can put it on and it absorbs quickly so that I can move on to the next serum/essence.
Thank you for sharing your experience!
Alice, I have never seen any benefit from algerine. Thank you for explaining this mechanism of action so well. I think it's just placebo. I hope you are well and have a good week 🌷
Thank you! Hope you have a great week too 🥰
You're hair is giving Galadriel vibes 🤍✨️ I love it !!!! Makes me realize I haven't watched The Lord of the Rings trilogy in FOREVER.
!!! saaaame. Ugh such a great series
Thank you for explaining this!!
Imo at least Argereline makes theoretical sense unlike some of the things I’ve seen advertised as alternatives for Botox or vitamin A … people get real …creative 😂
I did know at least Argereline was different but I really never understood how or why. I also didn’t realize it was in the multi peptide serum that really is a good serum!!
EXACTLY!! There’s a reason behind the nickname, but…it’s still less “proven” than Lipotec would like to admit
Sometimes I think about how brands that market to us are also marketed to in their own way by ingredient suppliers 🤔
Same!
I’ve seen bakuchiol be labeled as a retinol alternative, and then a Botox alternative, and just can’t fathom how anyone could think these claims are true 😅.
@@AliceintheRabbitHole They are. Ingredient manufacturers have sales reps, and purposefully display certain info on their websites and catalogs, but at the end of the day it’s on the brand to do their own research, and hire people who are knowledgeable in ingredients and formulations.
Placebo effect is why I’m always skeptical of new skincare claims. Argireline sounds promising, but based on the results that I’ve heard people say they’ve gotten it sounds no different than the results I’ve gotten from using other peptides. I’m not a fan of TO , so it’s a pass for me, but argireline in general looks promising, and I look forward to seeing what science and users are saying about it in a couple years from now.
Likewise! I think that with the interest in peptides, we could drive further research. And I certainly hope we do!
I feel like I was just in class lol! Thank you for the great explanation including illustrations, just what I needed to really get what you were saying. Really interesting discussion, thank you!
Glad it was helpful! 🥰
I. LOVE that you are a research scientist! I learn so much from you! I have used TO Argiriline for way too long, to have not seen any results. :( 😢. I am almost 80 and been into “anti-aging “ skincare for only about 4 years (well, since the lockdown, and I got bored and tuned into too many you tubes-lol). I wonder if I am too old to see many results from any anti-aging products? I do have good skin, have always taken care of it, but never even heard the words “retinol or tretinoin”, until lockdown! I quilted, cross stitched, punch needled, all crafts, but was never tied to the internet…like now! 😂. Could I be spending my retirement income unwisely? 🤦🏼♀️ 🤷🏼
I have tried and enjoyed both of these Ordinary serums. I did notice a difference in my skin, so I'm a fan! Thanks Alice for this informative video. ❤
Thanks for sharing your experience ☺️
Thank you for this deep-dive, Alice! So interesting. For me, even if Argireline DOES have a minor effect, it isn't changing the structure of the skin in any way, so it's just smoke and mirrors. I guess that's no different from makeup (which I don't wear), but I just want my skincare to be making long-term improvements: not just pretending it is. One could argue that Argireline, if it works and if you use it until the end of time, could ultimately inhibit static wrinkles, but that just seems like a lot of effort for no guaranteed payoff. I'm certainly not devoting a whole serum/step in my routine to it, and I've outgrown The Ordinary in general. They can keep their horde of "+HA" serums (as if that's somehow still a marketing point?). Finally, most of us discussing this topic use a metric excrement-ton of skincare. It would seem that unless you are isolating over a long period of time, it's nigh impossible to know if it's the Argireline or the gestalt of everything being used.
I think about that last point a lot, and it’s why these days I kind of gravitate away from any kind of personal claims. I’ve said it before and will say it again: all of us skincare enthusiasts would be excluded from a research trial 🤣
It 100% works, imo, on my forehead. I used to furrow my eyebrows so easily every time i even squinted. Now it's much more difficult to make that face. My elevens have faded significantly
Very interesting. I am a no needle Gal too. Have a great week ❌️ ⭕️
Thank you! You too! ☺️
Thank you for making the mechanism of Botox and acetyl hexapeptide-8 more understandable. I have dry, mature skin. I used TO’s Argireline around and between my eyes. Between my eyes are little frown lines😠, I did notice that they weren’t not as deep while using acetyl hexapeptide-8, nor can I make those lines as easily. I now use products containing acetyl hexapeptide-8, but I didn’t get a new bottle of TO’s Argireline during the November sale. I appear to have kept some of my results, but not all. I think it worked better in TO’s product because it is likely more concentrated.
It’s something I really respect about the ordinary: they tell us concentrations! And yep, 3-10% (of the 0.05% solution) is the recommended use level, so the ordinary is on the higher end with Lipotec’s suggestions!
I have been using matrixyl and argireline combo for years now and Buffett now multi-peptide + ha at night every day I think it helps slow the process and I saw a difference after 3 months. I am 58
Thank you for sharing your experience!
most welcome @@AliceintheRabbitHole
Same here, I do not know if it is placebo effect or a true result, hmm 🤔 Great video ❤
We can definitely say peptides hydrate due to their structure! 😃
Now I can't say anything long term but i got this Ordinary solution a couple days ago. I am using as a potential inhibitor for 11 lines and I also use this on my top lip to try to prevent mouth lines as well. I do notice inhibition, especially on my forehead. What I would be interested to know if this will eventually decrease in potency as the skin gets used to it. I sincerely hope not as I think this product so far is an excellent and cheap addition to a skincare routine
This seems to fall in line with what I've seen on some derm channels whenever this comes up. I do like the wig and sweater.
Thank you! It’s such an interesting topic imo, and Lipotec is very convinced on their peptide (they even claim proof of the mechanism via catecholamine release but…I find it a bit, let’s say optimistic lol)
I have the ordinary multi peptide plus copper serum and try to use it on the days I don’t use vitamin c serum which means I don’t use it often. Think some have debunked using vitamin c and copper together but even so, I don’t like applying multiple products in the morning. Serum, sometimes moisturizer and always sunscreen is all I can handle. I didn’t realize ordinary multi peptide serum has argireline. Wonder what the precentage is compared to stand alone argireline. Great point about thinner skin being more receptive to argireline Alice!
Thx Alice fir the video . I have been using TO Argireline for a few years . I guess it does make difference as far as topical goes . May I suggest you to try the Haruharu 5 Peptide Concentrate Cream which I believed include argireline . I am on it for 1 week hoping it will reinforce the strength of argireline . Love to hear your opinion . ☺️
Writing that one down, thank you for the rec! ☺️
Anyone know why the ordinary or Argireline solution made my forehead have so many fine lines and incredible sagging it's the only product I introduced different into my skin care and it was very harsh dried me out very badly caused severe sagging and I can't reverse it so far and I don't understand and yes I used good moisturizers on top of it so wondering if this happened to anyone else!!!!
TIL about Socrates final drink, and I've barely started the video! This is science with Alice.
Ye wh-Olde Foods
The copper peptides by the ordinary are wayyyy better and have argireline in it! I will still get Botox but it has saved me during pregnancy AND makes Botox last longer for me. Also get the off brand botoxes like Jeaveau, last longer for me and are cheaper!
Thank you for the sciencey breakdown! Curious who first thought "let me inject myself with this deadly poison and see what happens" - maybe trying to self-embalm?
If you want the answer, I did come across it! I think links don’t work on RUclips anymore so I’ll share the citation instead:
Scott AB, Honeychurch D, Brin MF. Early development history of Botox (onabotulinumtoxinA). Medicine (Baltimore). 2023 Jul 1;102(S1):e32371. doi: 10.1097/MD.0000000000032371. PMID: 37499077; PMCID: PMC10374179.
Hey Alice, given the topic today- I was wondering if you've ever heard of/uses the Snoxin II serum from Indeed Labs? Obviously it's not Botox in any way, but as a serum it reminds me of the Matrixyl & Arginine (sp?) combo. In fact it contains some of those ingredients.
Anyway, if you ever get a chance I'd love to hear a review or just what your thoughts on this serum are.
ETA: I do own a tube of it byt I've only just recently started using it. And I dont tend to *love* when serums have dimethicone high up ik the ingredients because of layering and pilling issues. (Love silicones in a moisturizer or in hair conditioner, though! lol)
Also I should add- if anyone else reading this has used the Snoxin II peptide serum, please share your experiences!
Thank you for talking about the placebo effect! I am always thinking about it in the back of my mind. Did this really work or did I just will it to? My mom is a chemist, I blame her for that one. 😂
Yuuup, I think about it constantly 🤣
I think people get confused because the term "organic" is federally regulated, whereas "natural" isn't regulated in any way.
I wonder if the Medicube age-r booster would help with penetration and effectiveness? I’m thinking about trying it that way to see if it helps Botox last a little longer. I am using it now to help my brow look more lifted as they’re pretty heavy naturally. I’m not expecting miracles by any stretch of the imagination. I’ve also become a little obsessed with the Age-R booster. I totally thought it was a gimmick but my products all work so much better now.
Mmm. I do use it! I’m very hesitant to make any firm conclusions, but…well…I use it, with peptides!
The problem with argireline is the big size of the molecule, it seems impossible to pass through the skin.
Very informative! It looks like the ordinary’s copper peptide product also has argireline, correct?
Yes But not as concentrated
Yes! Along with argirelox (snap-8 …go figure it’s the same snap-25-based principle, although supposedly stronger)
Botox keeps my muscles from going into spasm and locking up. It comes in a bottle. End of story. ❤
Lol right, I’ve never understood why “Botox in a bottle” stuck as the nickname. That already exists, and it’s Botox!
Okay, I’m only five minutes in, but I had to say…. I just opened up the RUclips app to continue watching some thing I was watching earlier and your video was at the top of my notifications. I said “oh I’m about to place a stylevanna order, let me go see what she needs me to add to my cart.” 😅😅
Then I hear the topic, and think “oh, no, I just need to be reminded to make my Botox appointment .”😅
🤣😂 I have a Vana cart in progress too (I guess that’s fairly continuous lol)
Hi. Making baked pasta and watching ❌️⭕️
Oh yum!
I get more concentrated Arg. from a site for diy cosmetics. Not cheap at all! I put a single drop in my AM toner on my palm and the effects have been slight but noticeable. TO did nothing to me.
I don't even know the concentration of my mixture, but some how it works.
Oh interesting! Yes, it’s quite a pricey peptide. Do you purchase the solution or the powder?
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I was today years old when I realized you wear wigs, i thought you were just a hair dye addict, lol
Haha yep! Wigs are sooo much fun 🤩