Adrenal Insufficiency | Clinical Medicine

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  • Опубликовано: 28 июл 2024
  • Premium Member Resources: www.ninjanerd.org/lectures/ad...
    Ninja Nerds!
    In this lecture, Professor Zach Murphy will present on Adrenal Insufficiency. We will discuss the pathophysiology, including the inadequate production of adrenal hormones such as cortisol and aldosterone, which can be due to primary adrenal failure (Addison's disease) or secondary causes affecting the pituitary. The lecture will include a discussion on the clinical manifestations, such as fatigue, muscle weakness, weight loss, and electrolyte imbalances. The digital presentation will begin with the diagnostic approach, highlighting the importance of serum cortisol levels, ACTH stimulation tests, and imaging studies to assess adrenal and pituitary glands. Finally, we will review management strategies for Adrenal Insufficiency, emphasizing hormone replacement therapy to restore hormone levels and manage symptoms. Enjoy the lecture and support us below!
    Table of Contents:
    0:00 Lab
    0:07 Adrenal Insufficiency Introduction
    0:52 Primary Adrenal Insufficiency
    3:56 Adrenal Cortex Injury
    12:55 Secondary Adrenal Insufficiency
    15:53 Hypopituitarism
    20:38 Pituitary Suppression
    23:27 Classic Findings of Adrenal Insufficiency
    35:52 Complications of Adrenal Insufficiency
    44:26 Diagnostic Approach to Adrenal Insufficiency
    47:49 Treatment of Adrenal Insufficiency
    51:11 Comment, Like, SUBSCRIBE!
    Retired Ninja Nerd Lectures:
    • Adrenal Insufficiency ...
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    #ninjanerd #endocrine #adrenalinsufficiency

Комментарии • 67

  • @abdelrahmanmetwally8976
    @abdelrahmanmetwally8976 4 месяца назад +19

    Wait a minute, you apologised a few days ago for this masterpiece???!!!
    You smashed medicine , you monster ❤️❤️🔥🔥🔥🔥🔥💪💪💪💪💪

  • @julelaynecurry6714
    @julelaynecurry6714 2 месяца назад +2

    Thank you SOOO much for all your hard work in putting together these videos. Your clinical medicine series videos have been by far the most helpful resource for me for studying for Step 2. We love you!!!

  • @swissms5808
    @swissms5808 День назад

    Thank You very much for all the work, time, and execution of these very informative videos!! 👏🏼 👏🏼

  • @mofeokoromadu2962
    @mofeokoromadu2962 16 дней назад

    You are always my go to channel. Thank you

  • @Mav2208
    @Mav2208 2 месяца назад

    Amazing lecture as always. Ty Zach!

  • @chrisso_o897
    @chrisso_o897 4 месяца назад +2

    literally the best teacher

  • @arjunsunil2527
    @arjunsunil2527 4 месяца назад +1

    Thank you for the videos

  • @valviv
    @valviv 4 месяца назад +1

    Great video, thanks Ninja Nerd!

  • @bonesaw7
    @bonesaw7 4 месяца назад

    Excellent work as always

  • @mari.4018
    @mari.4018 3 месяца назад +1

    Thank you for this video

  • @WedGirl23
    @WedGirl23 3 месяца назад

    You are AMAZING!! Thank you so much!!

  • @BeverlyAtienoOkeyo
    @BeverlyAtienoOkeyo 3 месяца назад

    I love your teaching methodologies.

  • @nathaliacunha8386
    @nathaliacunha8386 4 месяца назад +1

    PERFECT. PERFECTION.

  • @ARefinedMe
    @ARefinedMe 2 месяца назад +1

    I have secondary adrenal insufficiency, caused by Pembrolizumab (Keytruda) immunotherapy. I see several new people every week joining the support groups online who have this side effect of immunotherapy, I think it’s becoming more and more common. I have almost no cortisol, almost no acth, and almost no DHEA. I also have almost no estrone, estradiol, estriol, progesterone, or pregnenolone. I have high FSH and FH. I was not in menopause prior to chemotherapy & immunotherapy.

  • @med-dr4yt
    @med-dr4yt 4 месяца назад

    Thank you very much

  • @lewvonos1485
    @lewvonos1485 Месяц назад

    Thank You for wonderful lessons!

  • @jamshidimomov1740
    @jamshidimomov1740 Месяц назад

    Thank you Zach!

  • @pontesaludablepontefitpont8606
    @pontesaludablepontefitpont8606 Месяц назад

    You are great. Thank you for sharing yor knowledge.

  • @japneetkaur1782
    @japneetkaur1782 2 месяца назад

    Thankyou sooo much for this

  • @miramyriam6616
    @miramyriam6616 22 дня назад

    best teacher ever !

  • @miahaller1730
    @miahaller1730 4 месяца назад

    your videos carry me through my advanced physiology class!

  • @shahiramohammadi7284
    @shahiramohammadi7284 4 месяца назад +1

    Best teacher in the world ❤❤❤

  • @user-ri6cg3sf3m
    @user-ri6cg3sf3m Месяц назад

    Thank you very much ❤

  • @Msrra7usam
    @Msrra7usam 2 месяца назад +1

    Thank you 💗

  • @mk-ek8pv
    @mk-ek8pv 4 месяца назад

    thank you!

  • @DannyRusso
    @DannyRusso Месяц назад

    Explicação maravilhosa! E muito obrigada por acrescentar legendas em português! ❤️

  • @kaitchou3405
    @kaitchou3405 4 месяца назад

    Excellent

  • @ashleyelisabeth6479
    @ashleyelisabeth6479 Месяц назад

    I have Addison's Disease and love that you covered this !

  • @justinenewman
    @justinenewman 4 месяца назад

    Outdone yourself with this one 👏🏻

  • @aubreymagasoa9050
    @aubreymagasoa9050 20 дней назад

    Thank you

  • @demure6055
    @demure6055 Месяц назад

    Thank you!

  • @muniruddinsk8078
    @muniruddinsk8078 2 месяца назад

    U r amazing teacher .. love and respect 🙏🙏❤️

  • @dulcetverse
    @dulcetverse 28 дней назад

    Thankyou Zach❤

  • @robertmarking817
    @robertmarking817 Месяц назад

    Wow!!! Agreed this is a masterpiece presentation!!!👏😊

  • @Think_Up
    @Think_Up 3 месяца назад +6

    Our kids asthma specialist had us put a humidifier inside their room which we later learned contributed to mold and dust mite growth, making their asthma chronic. He also prescribed FLOVENT, a steroid inhaler at a dose 4x what it should be for our tiny daughter and it shut down her adrenal system, she nearly died in ICU before an endocrinologist figured out the cause and treatment (cortisone helped her recover over 6 months until she was ok again). This doctor should be behind bars, but he's out doing it to thousands of other kids with the full support and profit of pharma. This system is not helping us. We got our kids off of the inhalers, removed the humidifier and they've been fine since.
    I'm not diagnosing other's conditions or situations but I'm a parent who nearly lost my child due to gross misuse of these drugs on my daughter.

    • @sneakypress
      @sneakypress 2 месяца назад +1

      Please do not stop spreading your message .
      It’s relevant in all areas of health and medicine .

    • @mewmannamwem6087
      @mewmannamwem6087 Месяц назад

      Hope she gets well soon !
      get the papers and sue them !!
      you will save hundreds of lives

  • @md.tahmidridwan9726
    @md.tahmidridwan9726 День назад

    Thank you sir

  • @iliyaghiyasvand
    @iliyaghiyasvand 4 месяца назад

    You are amazing❤️

  • @ManikanthaGaddadevaramat-mu6ii
    @ManikanthaGaddadevaramat-mu6ii 3 месяца назад +1

    Excellency at its best❤

  • @narjesalbazi7190
    @narjesalbazi7190 2 месяца назад

    Thanks

  • @Roxxy523
    @Roxxy523 3 месяца назад +1

    Sounds like your explanation fits some dysautonomia/ pots syndrome symptoms

  • @yahyaabdullahi7625
    @yahyaabdullahi7625 3 месяца назад

    You are amazing

  • @s_b2346
    @s_b2346 4 месяца назад +1

    From Yemen, big thanks

  • @milosforman5221
    @milosforman5221 4 месяца назад

    Awesome

  • @rokayaenafielmetni5232
    @rokayaenafielmetni5232 5 дней назад

    I SWEAR MY PROFESSOR COULD'VE JUST PLAYED THIS! i sat there for 2H n understood nothing but Zack in 51 mins made it all click

  • @peachy19968
    @peachy19968 3 месяца назад

    You rock

  • @ahmedaskari881
    @ahmedaskari881 2 месяца назад

    Love u zackk❤❤

  • @HakimGanya
    @HakimGanya 3 месяца назад

    da best

  • @ivaldohadi886
    @ivaldohadi886 2 месяца назад

    zach explain it like drinking water

  • @lasurfette7830
    @lasurfette7830 Месяц назад

    Why do I maintain a normal blood sugar when untreated for SAI if cortisol causes blood sugar to rise and my cortisol tanked?

  • @edenthedivine
    @edenthedivine 12 дней назад

    Time 16:47 what if a pregnant mother does not have any pituitary/ adrenal/ endocrine issues before or during pregnancy… what would you guess would cause the new born to be diagnosed with hypopituitary?

  • @Katie-vy5rd
    @Katie-vy5rd 2 месяца назад

    Eosinophilia? Why would that be the case? And how high?

  • @MoncureCoyote
    @MoncureCoyote Месяц назад

    Are there any other microbes that infect and deteriorate the adrenals? Never-ending. You answered.

  • @MoncureCoyote
    @MoncureCoyote Месяц назад

    How can my mother have Secondary and a tumor and I also have Secondary (looking for a tumor)? Is this genetic?
    I have been in Addison crisis. If I can tell you guys it is AWFUL for the patient... Multiply awful x 1,000,000. INTENSE headache, vomiting, more intense headache, lots of urination, drink water, urinate it back out... Then, you just want to lie down and go to sleep. Luckily (I didn't know I had Addisons), I called a friend and told him I was dying. I didn´t know I was dying but it felt like dying. They called 9'11. You should know that intense crying and greiving sends me into Addisons Crisis. I don´t know if this is true for other patients. I was out of the country. I am very surprised the abulance knew to give me steroids.

  • @otuokwulillian9092
    @otuokwulillian9092 19 дней назад

    ❤❤❤

  • @kaboom3908
    @kaboom3908 Месяц назад

  • @shi5702
    @shi5702 Месяц назад

    I have an upcoming SOAP note on anadrenal crisis case, without you my ass is grass 😭

  • @bootatoboo
    @bootatoboo 3 месяца назад +2

    why isnt CAH considered primary adrenal insufficiency?

    • @unsaiftikhar8580
      @unsaiftikhar8580 2 месяца назад

      CEA is because of congenital absence of 21OH and manifested in young children.....

    • @unsaiftikhar8580
      @unsaiftikhar8580 2 месяца назад

      CAH*

    • @abhishekkaushal5267
      @abhishekkaushal5267 Месяц назад

      In CAH there is deficiency of 21-OH enzyme which cause decrease in aldosterone and cortisol and switch the pathway more towards the synthesis of androgen

  • @mandarinofracito1821
    @mandarinofracito1821 Месяц назад

    Yo I ❤

  • @user-ug9sb6hg3q
    @user-ug9sb6hg3q 3 месяца назад

    🎉🎉🎉🎉

  • @sanjith1179
    @sanjith1179 4 месяца назад

    6 th like sir, I'm pratheesh from india ( Tamil Nadu).am big fan of you sir.say one hi sir.

  • @user-bu9mk5hd1y
    @user-bu9mk5hd1y 4 месяца назад

    💯🥷💯🥷💯🥷💯

  • @ahlam-yu1kk
    @ahlam-yu1kk Месяц назад

    You are AMAZING!! Thank you so much!!