I'm 40 But My Biological Age is 23. Here's How I Did It - Chris Mirabile
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- Опубликовано: 1 июн 2024
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Timestamps:
00:22 How Chris Started Slowing His Biological Age
05:00 What Are the Hallmarks of Aging
14:15 Targeting All Hallmarks of Aging At Once
18:15 Clinical Trials on Novos Core
27:30 Rejuvenation Olympics
36:30 Longevity Tests and Biological Age Clocks
46:29 Chris' Longevity Routine
59:35 Is Chris Getting Healthier in His 40s or Not
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Disclaimer
I do not own any of the video clips used in this video. The legal rights belong to the legal copyright holders of said content. I have used them under the 'fair use' policy and have done so for entertainment and educational purposes only.
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Timestamps:
00:22 How Chris Started Slowing His Biological Age
05:00 What Are the Hallmarks of Aging
14:15 Targeting All Hallmarks of Aging At Once
18:15 Clinical Trials on Novos Core
27:30 Rejuvenation Olympics
36:30 Longevity Tests and Biological Age Clocks
46:29 Chris' Longevity Routine
59:35 Is Chris Getting Healthier in His 40s or Not
Longevity and Anti-Aging Playlist: ruclips.net/video/5KNsfEBXKMg/видео.html&ab_channel=SiimLand
They forgot the most important hall mark... Dont be poor lol
💯💯💯💯💯
The poor man's diet is the healthiest ❤
Actually, the greatest wealth IS health! Good health, of course.
You Can't Change Fact Guys 👀
Cultivate your own food and being poor won't be a problem for aging
TL:DW: "Trust me, buy my product"
Any decent trainer will tell you that 80% of your gains come from diet. So, instead of spending all that money on testing, I'd rather spend it on berries, greens, mushrooms and a variety of fruits and veggies along with whole grains and legumes. I do strength training, HIIT and cardo training 3 days a week and rest on the other days to recover. I get to bed on time and don't stress. People guess my age is somewhere between 40 and 50. I'm actually 73 and feel about the same energy level as when I was in my 20's..
Amazing
I'd rather eat what my muscles and body is made of, saturated animal fat and meat. I spend my money on grass fed, grass finished beef. Bones, beef liver and heart, eggs, raw dairy, and other animal products.
@@windexbleach2205 Agree 100%. I'm 50 and look and am 10 years younger
@@ThePeterR66 More power to you.
There is no good human nutrition science to support the vegetables are good for you hypothesis.
I'm 58, I look like 40 but inside I'm like 185.. I don't get it.😂
😅😅😅😅😅😅
"It's not the years, it's the mileage"... Indiana Jones
😅😅😅
I'm 53, but people say I don't look a day over 52. Working on it.
Beet root extract for 2 months now and ive been sleeping very well on my own without melatonin or sleeping pills 💊 💪💪💤
Watch for kidney stones. Beetroot can increase the risk.
In powder form,wow!
Great conversation - thank you for bringing Chris on for an interview!
Wow iam only 8 minutes in and it's a total info bomb, thanks siim
That was pretty conscise, thanks for this guest!
My father’s side of the family all look very youthful as they age and grandpa lived independently until he died aged 97. I lie about my age and people assume I am 20 years younger. At 71 I can still run a 5k in under 43 minutes with patchy training and I lift heavy and don’t have any age related issues like joint pain. I do all the right things although I need to control my calories again after six months off. HRT is very anti-aging for women. That always gets left off the list.
My son still looks mid twenties in his thirties. So I think looking young really is a good marker.
My father died at 64 but he was a heavy smoker all his life. So genetics only gets you so far.
Agree 100% about the HRT!
Great interview!!!
Siim i love ur vids man, can u pls do a video on lik the top 10 or 15 supplements to take for longevity? I follow a lot from u and from blueprint and try to combine it to make my own routines!
Ideal approach ❤❤
Nice and good information 👍
Great show
Siim, which epigenetic test(s) do you recommend?
Want to do a before / after intervention 🔍
Great episode! 👏
Can you do a shorter version siim? Thank you!
The LDL comment at 41 min threw me off. A study out of Denmark just came out linking an LDL of 135-140 with much less heart attacks and atherosclerosis. So long as HDL and triglycerides were low
Can you please share the link of that study?
Yeah LDL isn’t the “bad guy” - the guy also said he would consider a statin so he’s behind the times on LDL
Someone previously asked about step count in a now deleted comment, and at what point does increased step count start to negatively affect epigenetic age. . I am going to guess the study below was the relevant study referred to by the guest. It looks like grimage increased after around 11,2471 daily steps . There are u shaped curves based upon amount of vigorous exercise and MET hours as well. Though the study appears to differ from what the guest said. The way I read the graphs, is that those that did the most exercise had the same or worse grimage results than those that did the least, as the curves were relatively constant on both ends. This would suggest to me that overdoing it by a large amount may wipe out all of the benefit that exercise has in terms of grimage results. That is, if you believe that grimage optimization has benefits.
Fox FAU, Liu D, Breteler MMB, Aziz NA. Physical activity is associated with slower epigenetic ageing-Findings from the Rhineland study. Aging Cell. 2023
Of course, grimage seems to be a dopey mesaurement when we have mortality stats. For those under 60, we see decreasing all cause mortality with step counts going up to at least 16,000 steps daily in vthis meta analysis Mortality may decrease further for those under 60 after 16000 steps, but the graph in the study stopped at 16000. For those 60 or over, mortality increased after 8000 steps, suggesting that seniors should not overdo it.
Paluch AE, Bajpai S, Bassett DR, Carnethon MR, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kraus WE, Lee IM, Matthews CE, Omura JD, Patel AV, Pieper CF, Rees-Punia E, Dallmeier D, Klenk J, Whincup PH, Dooley EE, Pettee Gabriel K, Palta P, Pompeii LA, Chernofsky A, Larson MG, Vasan RS, Spartano N, Ballin M, Nordström P, Nordström A, Anderssen SA, Hansen BH, Cochrane JA, Dwyer T, Wang J, Ferrucci L, Liu F, Schrack J, Urbanek J, Saint-Maurice PF, Yamamoto N, Yoshitake Y, Newton RL Jr, Yang S, Shiroma EJ, Fulton JE; Steps for Health Collaborative. Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public Health. 2022
People who have cancer and who are sick and dying don't move at all, because their body is weak and preserving itself to stay alive. That's the problem with epidemiology and inferring causation from 16,000 steps.
That's why scientists do covariate analysis in studies. From the study at issue, "Model 2 also adjusted for age, sex, race and ethnicity, education or income, body-mass index, and study-specific covariates for chronic disease (eg, diabetes, blood pressure, history of cardiovascular disease or cancer, and medications), self-rated health or functional status, accelerometer wear time, and lifestyle factors (eg, smoking and alcohol; appendix p 5). Investigators of participating studies were asked to complete sensitivity analysis excluding deaths within the first 2 years of follow-up."
That 11k number is what I assumed he meant
Gonna try that face scan and look more into this product. what was the step count that was “too much”?
Let’s cut to the chase! Ingredients shortlist?
Starts at around 17:00
Please make a video on alpha-cetoglutarate. Great content!
Yes! Do it!
Helps with hgh.
I am going to turn 48 this coming June and most people think I am 38 years-old. While I have to say that daily exercise does play a role on how younger you look the real reason is no marriage and no kids ..! 😊😊
I'm 74. My biological age is 63. Unfortunately, day to day, I feel like crap. I feel every bit of 74. We don't have the full picture.
What is your routine, diet and supplement stack?
@@OpenlyBritish without going into detail, I'm doing 90% of the things I'm supposed to be doing including diet, exercise and supplements. Hence the -11 year difference in ages. But I'm getting arthritis that limits my mobility and other ailments one would expect of a 74 year old.
My point is, it's missing something.
Nmn?
@@menonshahariyar5845 no
@@bill9989Maybe you are doing something wrong. Have you checked your vit.D+K routine? Or if you are ttaking something too long?
When it comes to exercise at least from the performance standpoint the proven rule is very simple. You put pressure on your body as a signal to invoke physiological adaptations. So in another words you deliberately damage your body in order to force your body to adaptation. As long as you allow your body to fully recover from whatever exercise you do your performance will go up and I believe it's probably safe to say that for the most part that is also how it works with health and longevity. In more nuanced view we know that as you exercise you occur damage to your bones and ligaments and other parts that requires more time to recover so there is not a simple solution but as long as you allow your body to catch up on all levels you will be more adapted and therefore get more benefit from exercise.
Enjoyed! I’m wondering if Chris has any content explaining his views on sunlight further. It’s kind of a big one since sunlight is embedded into our biological systems from the beginning of our existence. Also wondering if he can comment on statins more.. if he believes statins will destroy your mitochondria (CoQ10), if blocking cholesterol increases cellular stress, plus his thought on the increase in ALS, heart attack, etc..
Red meat is important for menstruating women however
Somewhere around the cost of athletic greens, but probably more beneficial. I'm impressed that they're not being as greedy as timeline pomegranate extract😂😂
don`t forget to live
Eating refined sugar speeds up aging just as fast as smoking cigarettes.
Damn I just bought fruity pebbles😮
Awesome
My experience is much different. I thrive on animal foods - mainly red meat and eggs. The only vegetable I eat is organic white California grown basmati rice. I find it is good to have about 100 carbs a day and white rice seems to be the cleanest way to access carbs. I find that having carbs in the evening does not cause a higher sleep score. I eat in an 8 hour window staring at 6 am. No food after noon. Sleep just fine. I focus primarily on supplementing with NAC, Glycine. Taurine. Creatine and L-Citrulline. These nutrients insure the substrate material needed for the body to be able to perform its functions effectively. These types of nutrients are more available in animal products and less so with plants, which also carry anti-nutrients and abrasive (to the gut) and unnecessary non-soluble fiber. I am 70 and my functional doctor runs a battery of blood tests every six months and likes my progress. I have the same body comp as when I was 21 and appear to be very healthy. There is more than one way to skin a cat.
Can you take GlyNac, Taurine and Lcitrulline together as a mixture or need to be taken separately? Cheers!
@@danieldaniels5034I I buy them separately in bulk - unflavored and unadulterated- and mix them together in one single drink - about 4 ounces of water and then shoot it down three times a day. Totals for the day are NAC 2.4 grams, Glycine 9 grams, Taurine 6 grams, Creatine 5 grams and L-Citrulline 6 grams.
I'm mostly a strict carnivore, other than special occasions when I might eat something else that was personally made by a family member. Rice is a decent option, for those who want carbs, at least assuming the source is clean. But if the soil is contaminated, rice has been shown to uptake and concentrate heavy metals like lead. It's wise to choose organic from a place like California that has strong regulations.
As for supplements, I've at times used some of the ones you mentioned. And I still have some of them in my cabinet that I haven't used up yet. But I'm starting to change my mind. Except in specific cases of deficiencies, it seems wariness might be a better relationship to anything that doesn't come from whole foods. Supplements, or anything industrially processed, can have contaminants, undesirable ingredients, and high deuterium.
I'm particularly concerned about excess deuerium that will harm the mitochondria and much else. So deuterium depletion might be the single greatest upstream factor in determining health and aging. One of the advantages of a carnivore diet is it's the lowest deuterium diet possible; as opposed to carbs like rice (and seed oils) that are high deuterium. And I've combined that with deuterium depleted water.
So you're reversing aging by eating known carcinogens and bragging about it? Good for you Skippy!
Great regiment! Try Qualia NAD. Pumped me sky high quickly.
Excuse me if I am wrong here but I thought the goal of these drugs was to cause apoptosis in senescent cells, not reduce their size? Also, I would recommend anyone add C15:0 to their stack. It is better than fish oil in most regards.
All this "biological age" silliness is getting out of hand. We're not there yet.
As someone who is 11 years (biological) younger, I agree with you.
It actually works. It sounds like you failed.
@@MarieLamour-cv1jc It actually doesn't. We don't even understand aging all that well yet. To think we can accurately measure one's "true age" or "speed of aging" is not science. It's marketing. And you've fallen for it.
As one of many examples, the maximum human lifespan is 120. So theoretically, an actual 23 year old that plays their cards perfectly, has the potential to live another 97 years. Can you say that about a 40 year old man claiming to have a "biological age" of 23? Almost definitely not. So what does it even mean to say he's "biologically 23?"
All it really means of course is that he's as healthy as an average 23 year old. Meaning that it's a measurement of health, not of "aging."
@@MarieLamour-cv1jc It actually doesn't. This "biological age" business is not science. It's marketing. And you've fallen for it.
Just one of many examples: the maximum human lifespan (so far) is about 120. Meaning that an *actual* 23 year, if they play their cards right, has the potential to live another 97 years.
Can you say the same about a 40 or 50 year old man claiming to be "biologically 23?" No, of course not. So then what does it really mean to say they are "biologically 23?" At most, all you can really say is that they are as healthy as an average 23 year old. Meaning that it's not a measurement of "aging" at all. Just a measurement of health.
It has some value in that. But a 40 year old man claiming to essentially be 23 is just silly. Silly claims like this are just a way to stir up attention, view, sales, and funding for research (aka: marketing.)
@@MarieLamour-cv1jc It doesn't though. It's not science. It's marketing. And you fell for it.
SIIM a video on resistance bands
I took the face age test and came out at age 24 for my face and 27 for my eyes. I'm 52 years old. Almost everyone new who I meet, thinks I'm way younger than I really am. Most people think my husband is my father and my 28 year old son is my brother. How accurate is that face age predictor? I'd like to know the results of others.
Inaccurate and baseless measures. You’re 52.
What is a face age test?
50... Face app reports 19... Either something is wrong with the program or something is wrong with me LOL...
How long do you have to take the supplement to start noticing benefits?
Be aware of the placebo effect. You shouldn't feel any benefit. If a supplement slows aging (a VERY good thing), it doesn't reverse or even stop aging. So even if it works well, you'll still be older tomorrow than you are today; not just as much as normal.
I watched the full hour and 9 minutes, feel like I aged 3 hours…
Key is to not make that knowledge a god but the life style it’s supposed to be
Currently what is the record for biological Vs chronological age
My Grandpa is 98 and he contributes his longevity to smoking cigarettes and shot of whiskey for lunch everyday.
That’s long life genes. Man would probably hit 120 if he didn’t smoke
@@Parkourmattstrongor maybe he’s had a ton of physical exercise, good diet, sunlight, good family connections, good sleep and other things most of his life and smoking is having zero effect on him?
Beer and Brautz smothered in sauerkraut. Have lots of chocolate and don’t forget the pastries.
Sim, please get Dr. Chaffee on..this guy is a plant guy..we need a meat guy also perspective..we are not rabbits bro..lions
Because some of us thrive with a whole food plant based, others with the carnivore diet, and some of us have a bit of everything and still manage to live til 98 years of age.
TLDR: "buy my supplement"
Even with no money you can do yoga, fasting, running, weight training... Eat salad instead of highly processed food, drink water and tea instead of softdrinks. Avoid carbohydrate and sleep a lot. Don't smoke and drink. If you do that, you'll be way healthier than 99% of people.
Intermittent fasting also helps you slow down your aging!
It doesn't
Cap
If someone is 80 years old and looks like they're 50 I'll pay attention when they promote a product
What kind of omega 3? I just saw a so called expert say that omega 3 can be bad for you, I have taken it for years. What's the story?
long chain like DHA and EPA. best to not have it processed in pills to oxidize. cod liver oil has Retinol (animal based vit A) that is an antioxidant that protects the long chain omega3 oil. plant oils high in omega 3 are mostly short chain line flax seed oil the short chain omega3 fat is called ALA. your body needs to convert the ALA to DHA or EPA and we have around a 2 to 5% conversion rate. there is one plant based long chain DHA/EPA source its Algae sourced (where most of the long chain omega 3 found in fish comes from)
Seems like a big advertisement. The "science" behind biological age measurement is weak. Time will tell.
There on to something,40 today isn't the same 40 from 1980
so another guy who doesn't know what he's talking about but he jumped to sell overpriced supplements...
So many things not addressed in this otherwise good interview. I would absolutely delve into more interesting things. . Missed opportunities.
If you look at people at 40+ ... you don't see many of these in the gym or working out or doing anything for their health. So the decline of performance is so understandable. The population averages are not very good representation of actual age related decline of potential ..
Was interested until I saw that they’re still selling NMN.
Cycloastragenol
Niacin
CA-AKG
what about epitalons 3x kinds , HGH ? KPV ? nmn , NADH ? insulin plant ? these ones for fast
I’m go go look this company up. First I have to find the spelling. I’m also going to look up the people mentioned. I already exercise, eat healthy, dance, never smoked, don’t drink. I sleep well thanks to Ben Bickman doing a lecture recently on salt. Sodium. Not table salt.
The pterostilbene and fisetin do nothing. I took them for years.
eat blueberries and strawberries. thats where the good data is, not these isolated compounds
@@j.c.higginbotham6401 too much oxalate, glyoxylate, glycolic acid and glyphosate exposure.
This reductionist pharmaceutical approach might be theoretically valuable but it is practically useless without addressing the issue of the destruction of our food supply system, toxic non food substances as staples in our diet, toxins in our air, water and food, and total curruption of our ancestral evolutionary lifestyle. Then the question is, even if this pill is beneficial, would it be needed at all if we solved 1st principle problems first.
🎉🎉
Dude, What is your Deadlift? 🏋♂️🏋🏻🦊
What are your biomarkers :)
@@Bezorgde_Burger Almost 70yrs I am oldest OG under the barbell at Local YMCA. What's your biomarker. 🏋🏻🏋♂️🦊
Yikes. I am 83 and should I even be here?
If you can make a RUclips account and comment at 83 years old you're not doing to bad haha God bless, definitely keep watching these videos and being here
Better late than never ❤
Glad you are😊
Of course you should. Dr Anthony Chaffee MD (the plant free MD) says we should be living to the age of 120 yrs.
I am a fairly active 84 year old vegetarian not diabetic or hypertensive;heart problems, 27 years back No intervention or drugs
Where is the actionable information? Most of this is well known by people following Siim. Here's some advice - keep videos under 10 minutes, give out actionable information. The detail of the protocols can be obtained from longer format videos for those who are into the research end of this.
Both short and long videos are important. People like different things.
There's millions of articles with quick tips. This video focuses on the biology and reasoning behind aging. If you want tips just look up an article or Bryan Johnson's protocal.
Very interesting. Humans are getting closer and closer to the fountain of youth.
🙂🙂🙂hi, I used my remote quantum testing and his biological age came back at *35*, not 23. his IQ is 133.
Simm's biological age is 25 according to my testing. Simm's IQ is 142.
Your Remote Quantum testing is Total BS! Stop posting VERY fake news!
How do you calculate their iq
My IQ is 72
Skin care. Nothing. No soap or shampoo and wholesome high Protein diet. I dwim daily and use sauna/steambath. Wonder what is hostory of daily shampooing of hair, bodywash and skincare unctions? At almost 70yrs am oldest OG under the barbell at local YMCA. Appear to be thriving. 🏋🏻🏋♂️🦊
so you use shampoo or not? :')
Avoiding lots of toxins in conventional personal care products.
Dude you r only 70...hav you looked at your endothelium?
@@ChrisZybeZ nope. 🏋🏻🏋♂️🦊
@@maidende8280 yep. Natural skin oils do the job
I figured out I can consume fish skin in the blender and I’ll try raw liver with fruit juice. Is this. A longevity protocol?
Fruit juice certainly isn't...
Def a disgusting protocol
Well, so except for a little vaping I'm doing everything right...so the goal now is to stop vaping .
Sim - like videos. Just some constructive suggestion- seems u do some little chortle or giggle frequently. Talking about health and disease so not sure why make these small like laughing sounds. Is very minor. But just an idea. Less distracting without. But always good info and thanks for efforts.
This was a one hour ad to sell and push his product. Thanks for wasting our precious time we can't get back.
Isn't this miserable tracking all this everyday? Swallowing all these pills and stressing out about any changed biomarker. Also the cost. I eat healthy. Get some sun. Exercise 3x a week and use basics like sunscreen/moisturiser/tretonoin. I feel good and look younger than my age.
If a senescence cell is cancerous...it w😊I'll not be senescent
Ridding the coat tails of Bryan Johnson.
I had a man customer 98 years old smoked since 15yr his entire life he looked around 50. For that guy smoking got a bad rap LoL
he looks really good. only a few years younger than me
I'm handsome
This evil world is coming to an end, still they crave for longevity! Wake up!!😢
back!? in 200017? 200017 is far far into the future.
He does look like he is 23
He looks late 30s
That isn't the point of biological aging. Maybe do some more research
He looks healthy.
He looks 29!!!
@@georgegeorgiou1511 40
Please also make a video on how to increase mean sexual health and night time erections
Bryan Johnson solved that
Oh man, another episode selling supplements 🙄
🤦🏼♂️
A girlfriend will more likely distract you and age you.
Please make a video on posture advice you got from AIWO INDIA 🇮🇳
Basically he is vegetarian I’m not sure about that.😂😂
Bro, you do not look 23 at all. Maybe 32.
His routine:
1) diet (counts calories), 16:8 fasting, carbs in the evening, lot of vegetables, legumes, moderate amount of white meat and eggs, lot of fish. No red meat, except some organ meat because of nutrients. Smoothie after workout (protein, creatine, mushroom powder). Multivitamin. Novo supplements
brian johnson beat you to it
ill buy tyhe ingredients seperate, way too expensive., suprised by the lithium
Scam!
dude looks old lol
He looks around 35 yrs old. He's doing something right ✅️ ❤
He has a thick neck and looks athletic
Looks Old? What are you smoking? Maybe your eyes have gone bad or something. You should see a Dr. ASAP!
He doesn't look old. He looks 40
@@falconone7230and he's 40 so he looks around his age