These types of videos really need to start revolutionizing the world of education. For those in university study trying to understand concepts like RNAi, videos like this bring our boring text explanations to life and really enrich the process. Loved it!
+zer o There is such a thing. As exciting as the concept might be, writing "siRNAs (dsRNAs) are cleaved by an RNase called Dicer in the cytoplasm, and are transported to their cognate mRNAs as ssRNA, whereupon they bind and catalyse cleavage of mRNA via Argonaut and are subsequently degraded (due to the loss of 5' caps or poly-A tails, I would imagine)" is a lot easier to view in an animation as it is above.
Crimbly I don't wanna sound like a dick but, if you get into it, your head fills up with the images and you get to manipulate them at will. If you wanna think about this stuff seriously that's step 1
An idea: A netflix ~8 episode series touring the interior of a cell, with David Attenborough narrating, with all the same storytelling that goes into Planet Earth.
+spagetti001 you should study them, surely there is lots more to learn about kinesins. For instance did you know that they also carry the mitochrondria around the cell? For example in the neurons they carry the mitochondria to and from the synaptic cleft. Failure of this mechanism leads to severe mental problems :-(
Perfect animation. Thanks! Sometimes it's complicated to just read about a process so dynamically regulated. Seeing it that way makes all the difference.
This video has to be the best one on RUclips for this topic. It manages to pack in all the correct terminology, clearly and concisely, while being accompanied by fantastic animations. I will definitely be recommending this video to my classmates! Thankyou!
This video is amazing! It's so rare that you find a bio animation that has really fancy animations, and also _isn't_ just a rehash of something that's already been done hundreds of times on RUclips before, like DNA replication or something. Thanks for making this so easy to understand!!! :D
@@DenysLazarenko Yup. It is too time consuming and too costly for anyone to do it, since there is no real economical benefit, and no foundation wants to fund such projects. Harvard were about to start a whole department for making science into 3D videos, but funding was cut due to being too expensive and "not enough use" of the material. They produced two amazing videos though.... Inner Life of the Cell: ruclips.net/video/B_zD3NxSsD8/видео.html Mitochondria: ruclips.net/video/RrS2uROUjK4/видео.html
but this modification is related to pre-mRNA , and here it's already modified , i know thats G-cap functions to protects mRNA from being digested by the RNases , but idk what's happened exactly here xD
Very cool. Students are very lucky to have these visuals. Much easier to understand than a school text book. RUclips is more of a learning tool if used correctly.
YES OMG! This is ridiculous, I cant believe this is happening in our bodies, we don't even have to control it it just happens like we have been created by the LORRD my man :') God loves us so he made us perfect!
@@pfeliciano4062 We haven't been created by a lord and our bodies are not perfect in any way. God doesn't seem to love the millions of people who die every year with genetic defects so what makes you think he loves you... or even exists in the first place.
Note. Contrary to a popular believe: Background music disrupts the ability to concentrate, store and remember information. It is esp. a hindrance for asperger personalities, naturally inclined to persue science studies.
Brilliant visualization of the micro-processes inherent in most, if not all, eukaryotic cells. It can reach a lot more people to see spatially what occurs at a near molecular level inside the cell membranes. Bringing the abstract academic into the everyday experience.
This is an amazingly structured and educational video. None of the other sites I visited made it easier for me to understand than this. However, one thing to consider is to show the complicated technical terms in text when used. That way, it's easier to look words up if you don't understand them. Oh and by the way, I liked the background music. It soothed me.
These videos are like the magical extendable tents in Harry Potter. It looks like 5:00 from the outside, but once you get in, it's actually 40 minutes.
I see videos like this and contemplate it with other thoughts such as neural networks and everything else resiliently working together which leaves me totally dumbfounded about how I cant even get close to grasping the complexity of living organisms. Mind blown!
Theoretically this method can be used for blocking rinoviruses to reproduce? I am not a specialist but ARN is the molecule that enables them to take control of the cells, and if can block a critical component to express than that can be a cure for a disease.
So great animation - simple and educative. People who try to learn this from books don’t memorise it so good than from this video animation. Thanks for that, great job! 🙏
So this is what is happening to our food? I read an article talking about this very thing. It is used in place of pesticides. My question is what are the long term effects this will have on the human body?
These videos are absolutely amazing ones let's one grab n understand the concept just in a while my making it visual you are helping many students like me who can understand better with visualization so hats off to your work n pls keep making more video!!❤️ I just can't expressed how much I loved the video n how you cleared all my doubts just in 5 mins! Pls keep making such videos! Great job!❣️❤️🙌
I had to turn captions on and pause at every step to digest what is being said. It's difficult to watch the animation and process the information at the same time.
the video is simply incredible..RNAi has a major role to play in curing of many diseases but what are the technical difficulties in introducing RNAi into the cells?Can anyone help me with this question?
These types of videos really need to start revolutionizing the world of education. For those in university study trying to understand concepts like RNAi, videos like this bring our boring text explanations to life and really enrich the process.
Loved it!
no such thing as boring text explanations
+zer o There is such a thing.
As exciting as the concept might be, writing "siRNAs (dsRNAs) are cleaved by an RNase called Dicer in the cytoplasm, and are transported to their cognate mRNAs as ssRNA, whereupon they bind and catalyse cleavage of mRNA via Argonaut and are subsequently degraded (due to the loss of 5' caps or poly-A tails, I would imagine)" is a lot easier to view in an animation as it is above.
+Criminal y vídeo
Crimbly I don't wanna sound like a dick but, if you get into it, your head fills up with the images and you get to manipulate them at will.
If you wanna think about this stuff seriously that's step 1
@@TheNeverposts Everybody learns and imagines things differently. There's no right or wrong way about this.
An idea: A netflix ~8 episode series touring the interior of a cell, with David Attenborough narrating, with all the same storytelling that goes into Planet Earth.
Director:Nucleus
Producer: Chloroplast
Treasurer: Mitochondria
Cinematographer:GA
anyone but david atenbourough, hes overdone a bit
fresh science fresh blood?
Watch cell at work
*WANT*
We're gonna be rich
I can't begin to describe how much I love the kinesin/dynein marching along the microtubule :D
+spagetti001 i need a favor of you
+spagetti001 you should study them, surely there is lots more to learn about kinesins. For instance did you know that they also carry the mitochrondria around the cell? For example in the neurons they carry the mitochondria to and from the synaptic cleft. Failure of this mechanism leads to severe mental problems :-(
Hahaha, same thing here bro.
They also are a primary cause of spinal muscular atrophies. If they do not work properly, the cell cannot properly repair itself. CRAZY!
best cat walk ever :D supermodel of the cell
Literally condensed a 50 min lecture into 5. Thank you. so clear. absolutely amazing
the animation was so good that could hardly focus with her
Yes, i also could not focus with her as i was engrossed by the animation :)
Yaaa truth...
Its theorized animation, not a video.. just a perception.
It seems that I'm also on the same page.... Had to close my eyes to concentrate on her explanation
Yes very true 😶🌫️
Perfect animation. Thanks! Sometimes it's complicated to just read about a process so dynamically regulated. Seeing it that way makes all the difference.
u look like emma watson! :)
@ptrt kiran lol
Yes i agree
I can't believe this masterpiece was created 12 years ago!
This video has to be the best one on RUclips for this topic. It manages to pack in all the correct terminology, clearly and concisely, while being accompanied by fantastic animations. I will definitely be recommending this video to my classmates! Thankyou!
This video is amazing! It's so rare that you find a bio animation that has really fancy animations, and also _isn't_ just a rehash of something that's already been done hundreds of times on RUclips before, like DNA replication or something. Thanks for making this so easy to understand!!! :D
This is by far the best video explaining this concept, i have been searching endlessly to find good sources on the topic
Why don't we have this type of great animation for like all the stuff?
ikr
+NMMRSTT indeed.. but as far as i can imagine, making this kind of 3D animation must take absolutely huuuuge amount of time and effort
@@DenysLazarenko Yup. It is too time consuming and too costly for anyone to do it, since there is no real economical benefit, and no foundation wants to fund such projects.
Harvard were about to start a whole department for making science into 3D videos, but funding was cut due to being too expensive and "not enough use" of the material. They produced two amazing videos though....
Inner Life of the Cell:
ruclips.net/video/B_zD3NxSsD8/видео.html
Mitochondria:
ruclips.net/video/RrS2uROUjK4/видео.html
economy, if there is ROI, people makes bullshit videos too...if there is payback they will certainly make it on larger scale
@@Wistbacka i don't think its only cost cause most schools and colleges take hefty fees and give legit bull shit education in return :)
At 3:54, the cleaved mRNAs are degraded because they are missing a poly-A tail or 5'cap, respectively.
but this modification is related to pre-mRNA , and here it's already modified , i know thats G-cap functions to protects mRNA from being digested by the RNases , but idk what's happened exactly here xD
@@George-bq9wv Can be non-sense mediated mRNA decay
can't explain how much this helped me thank you so much
Very cool. Students are very lucky to have these visuals. Much easier to understand than a school text book. RUclips is more of a learning tool if used correctly.
The universe is infinite. And even the inside world seems it too. Brings a new meaning to being alive.
This is the prettiest thing I have seen in biology in many many years .. why don't doctors illustrate lectures in such way💔
The human body is truly a bio-chemical engineering marvel
YES OMG! This is ridiculous, I cant believe this is happening in our bodies, we don't even have to control it it just happens like we have been created by the LORRD my man :') God loves us so he made us perfect!
@@pfeliciano4062 We haven't been created by a lord and our bodies are not perfect in any way.
God doesn't seem to love the millions of people who die every year with genetic defects so what makes you think he loves you... or even exists in the first place.
@@Thomas-nc9fz it probably doesn't exist man
Even if it exists it probably created the Universe, life formed on its own
I believe we humans and life on earth is a biochemical fluke that had occoured billions of years ago
THE animation kind of impairs my hearing ability , cant take them both together
yeah, it's too fast
Yrah I was just taken away by the animation.........
too many things were goin on .Yea
possibly the most entertaining and absorbing scientific animation i've ever seen
Gotta love the fleet footed Motor Protein :) And the Polymerase! Biology is absolutely amazing!
The animation and explation is too good any biotechnology student can relate to it easily.. the narration is also very clear .. loved it..
Thanks, I have bio board exam two days from now. These animations are helping me a lot in revising all the concepts.
I hope I do good in the exam😃!!
Hello brother 🗿
Excellent video! Explained such difficult concepts with ease and amazing animations. Thankyou!
That motor protein animation at last was so cute!!
Note. Contrary to a popular believe: Background music disrupts the ability to concentrate, store and remember information. It is esp. a hindrance for asperger personalities, naturally inclined to persue science studies.
Brilliant visualization of the micro-processes inherent in most, if not all, eukaryotic cells. It can reach a lot more people to see spatially what occurs at a near molecular level inside the cell membranes. Bringing the abstract academic into the everyday experience.
This is an amazingly structured and educational video. None of the other sites I visited made it easier for me to understand than this. However, one thing to consider is to show the complicated technical terms in text when used. That way, it's easier to look words up if you don't understand them. Oh and by the way, I liked the background music. It soothed me.
Great animation and amazing explanation, even after 12 years
These videos are like the magical extendable tents in Harry Potter. It looks like 5:00 from the outside, but once you get in, it's actually 40 minutes.
Perfect video
I absolutely adored!
I cried it's so beautiful
I'm gonna have to watch this again. I heard nothing the guy was saying the first time through because the animation was so good.
If you got too distracted to understand by the animation try watching it again with your eyes closed and picture the process as she speaks.
It's really amazing that these diverse biological mechanisms are taking place in our body
dayum. whatte video. well done yall!
Thank you very much for creating this animation and making this video available for free. I love it ♥️
Make a Netflix series with this animator ..... the world deserves it.
it's incredible how complex and yet beautifull the way genes acts with each other to answer the body neads. (with body i mean every leaving thing)
One of the best things ....I have ever seen
Thanks a lot !!!!!
Best animation ever seen💖💖💖💖
very professional and easy way to explain RNAi
This topic is a complex concept
And by visualise i understand it better
This is the best animation on the topic :p
I see videos like this and contemplate it with other thoughts such as neural networks and everything else resiliently working together which leaves me totally dumbfounded about how I cant even get close to grasping the complexity of living organisms. Mind blown!
I love the way it zooma out as though leaving a little solar system (music helps),
Animation and explanation (but animation OMG) were STUPENDOUS 👏👏👏
Super helpful for studying miRNAs and RISC! thanks
12 years ago. Like 12 years ago!!!! Just discovered this topic reading about Haemophilias treatment. Simply amazing
What an amazing video... I can watch it again and again 😍
Animation helped out immensely !! Finally, It makes sense!
yup......
Theoretically this method can be used for blocking rinoviruses to reproduce? I am not a specialist but ARN is the molecule that enables them to take control of the cells, and if can block a critical component to express than that can be a cure for a disease.
Amazing description.... Thank you soooo much.
please slow down. it takes time to digest all this.
you can slow your playback speed
Very well done video! This video displays many other accurate cell functions and gives a great explanation. Great job!
learning has become fascinating...thanks to such videos
The animation is mind blowing
Oh. My. God! Love this animation!!
@there4able The "walking" molecule is called kinesin. It's transporting a vesicle of some sort along a microtubule, which is that brown thread.
So great animation - simple and educative. People who try to learn this from books don’t memorise it so good than from this video animation. Thanks for that, great job! 🙏
this music slaps, easily the best part of the video
Brilliantly animated.
Keep up the awesome work.
its the best video to understand rnai mechanism
Thank you Pranav Pundarik Sir
Instead of reading, this video make my comprehension better... Thank you Nature :)
Feliani San jay a
So this is what is happening to our food? I read an article talking about this very thing. It is used in place of pesticides. My question is what are the long term effects this will have on the human body?
The graphics are cool!
This was really good, just what I needed to help with my Biology revision! Thanks!
The animation is so indulging.......love it....really helped.
Thank you it's been a pleasure to watch such an incredible animation. I have watced others from nature video and it is excellent.
These videos are absolutely amazing ones let's one grab n understand the concept just in a while my making it visual you are helping many students like me who can understand better with visualization so hats off to your work n pls keep making more video!!❤️ I just can't expressed how much I loved the video n how you cleared all my doubts just in 5 mins! Pls keep making such videos! Great job!❣️❤️🙌
The animation, the music, the voice.....
𝙀𝙫𝙚𝙧𝙮𝙩𝙝𝙞𝙣𝙜 𝙞𝙨 𝙟𝙪𝙨𝙩 𝙥𝙚𝙧𝙛𝙚𝙘𝙩.
I had to turn captions on and pause at every step to digest what is being said. It's difficult to watch the animation and process the information at the same time.
It is such a sweet and beautiful explanation. Thank you ☺
Wow this made my concept super clear. thank you so much
Just a Q
Does the RISC cut the RNA? So that it stops translation? Or it prevents ribosomes from moving to continue the production of the protein
couldnt understand the concept but I loved it
Stunning graphics. I'm currently reading Molecular Biology of the Gene 7 Ed chapter on Regulatory RNAs. Fascinating stuff.
My professor was unable to explain this even in 2 hours which you told in just 5 minutes.thank you
10 points question. What's the protein complex that moves on the microtubule? 4:33
Kinesin Protein
Kinesin, (+) end directed --> carrying a COPI-coated vesicle from the golgi to the ER--retrgrade
Amazing accurate animation... kudos.. plz bring more such videos on CRISPR , and other emerging tech
What a fine piece of animation :D
couldnt focus. on what she was saying because the video was so satisfying
Great animations and explaining!
such an amazing video!! I love love love♥♥♥♥♥♥♥♥♥
Beautifully presented and magnificently explained
2:30 onwards, my eyes kept on staring and brain rewind all molecular process i knew so far, this is an amazing job.. (y)
loved this. finally RNA Interference mechanism is going to settle in my mind.
I really like the video graphic animations, but white text with the key terms such as DROSHA/DRGC8/DICER/AGO/RISC/ETC would have been quite helpful.
This was an amazing video! Thank you so much for making it and please make more!
Great animation!
the video is simply incredible..RNAi has a major role to play in curing of many diseases but what are the technical difficulties in introducing RNAi into the cells?Can anyone help me with this question?
mam thank youuuuuu soooooo much for this wonderful animatiom i have ever seen ❤❤❤❤❤❤❤❤
Kiirrrrakkkkkkk🥰🥰🥰😘
Superb mam tq so much
Thank you for wonderful explanation
Nice animation and presentation
The animation is well made. It looks spooky at first, t helped me understand easily.
Thankyou so much for such a wonderful work!
So nice video ..cleared many confusions.
Kinesin walking like a boss there lol! loved the video thank you so much for the great explanation and the great visuals
Amazing animation tq to give us such video , after it see the rnai is tottaly cleared
Oh such a beautiful video!