RNA interference (RNAi): by Nature Video

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  • Опубликовано: 24 окт 2024

Комментарии • 577

  • @alejandronavarro4128
    @alejandronavarro4128 5 лет назад +1249

    An idea: A netflix ~8 episode series touring the interior of a cell, with David Attenborough narrating, with all the same storytelling that goes into Planet Earth.

    • @goodnessoverloaded1078
      @goodnessoverloaded1078 4 года назад +85

      Director:Nucleus
      Producer: Chloroplast
      Treasurer: Mitochondria
      Cinematographer:GA

    • @KingSlimjeezy
      @KingSlimjeezy 4 года назад +6

      anyone but david atenbourough, hes overdone a bit
      fresh science fresh blood?

    • @mlnz2991
      @mlnz2991 4 года назад +12

      Watch cell at work

    • @愛-m8l6l
      @愛-m8l6l 4 года назад +3

      *WANT*

    • @mkultramarine1692
      @mkultramarine1692 4 года назад +3

      We're gonna be rich

  • @spagetti001
    @spagetti001 8 лет назад +1007

    I can't begin to describe how much I love the kinesin/dynein marching along the microtubule :D

    • @darianadepablos3192
      @darianadepablos3192 8 лет назад +1

      +spagetti001 i need a favor of you

    • @EDUARDO12348
      @EDUARDO12348 8 лет назад +52

      +spagetti001 you should study them, surely there is lots more to learn about kinesins. For instance did you know that they also carry the mitochrondria around the cell? For example in the neurons they carry the mitochondria to and from the synaptic cleft. Failure of this mechanism leads to severe mental problems :-(

    • @didismit1766
      @didismit1766 8 лет назад +2

      Hahaha, same thing here bro.

    • @CrazycruxGaming
      @CrazycruxGaming 7 лет назад +3

      They also are a primary cause of spinal muscular atrophies. If they do not work properly, the cell cannot properly repair itself. CRAZY!

    • @jinghuawu3616
      @jinghuawu3616 6 лет назад +25

      best cat walk ever :D supermodel of the cell

  • @mikejackson9555
    @mikejackson9555 9 лет назад +999

    These types of videos really need to start revolutionizing the world of education. For those in university study trying to understand concepts like RNAi, videos like this bring our boring text explanations to life and really enrich the process.
    Loved it!

    • @TheNeverposts
      @TheNeverposts 9 лет назад +10

      no such thing as boring text explanations

    • @CrimBlack
      @CrimBlack 8 лет назад +40

      +zer o There is such a thing.
      As exciting as the concept might be, writing "siRNAs (dsRNAs) are cleaved by an RNase called Dicer in the cytoplasm, and are transported to their cognate mRNAs as ssRNA, whereupon they bind and catalyse cleavage of mRNA via Argonaut and are subsequently degraded (due to the loss of 5' caps or poly-A tails, I would imagine)" is a lot easier to view in an animation as it is above.

    • @zenonyanez4508
      @zenonyanez4508 8 лет назад

      +Criminal y vídeo

    • @TheNeverposts
      @TheNeverposts 8 лет назад +8

      Crimbly I don't wanna sound like a dick but, if you get into it, your head fills up with the images and you get to manipulate them at will.
      If you wanna think about this stuff seriously that's step 1

    • @flow4458
      @flow4458 3 года назад +9

      @@TheNeverposts Everybody learns and imagines things differently. There's no right or wrong way about this.

  • @Riceowl2012
    @Riceowl2012 11 лет назад +133

    Literally condensed a 50 min lecture into 5. Thank you. so clear. absolutely amazing

  • @1490063
    @1490063 8 лет назад +389

    the animation was so good that could hardly focus with her

    • @shreyad262
      @shreyad262 6 лет назад +9

      Yes, i also could not focus with her as i was engrossed by the animation :)

    • @vijayadurai-vkshreemetals1848
      @vijayadurai-vkshreemetals1848 5 лет назад +1

      Yaaa truth...

    • @agatolwey6218
      @agatolwey6218 3 года назад

      Its theorized animation, not a video.. just a perception.

    • @rajsingh-rk8dw
      @rajsingh-rk8dw 3 года назад

      It seems that I'm also on the same page.... Had to close my eyes to concentrate on her explanation

    • @vinaysraman100
      @vinaysraman100 3 года назад

      Yes very true 😶‍🌫️

  • @lolaS2eric
    @lolaS2eric 10 лет назад +108

    Perfect animation. Thanks! Sometimes it's complicated to just read about a process so dynamically regulated. Seeing it that way makes all the difference.

  • @YouAreTheRaidBoss
    @YouAreTheRaidBoss 9 лет назад +265

    Why don't we have this type of great animation for like all the stuff?

    • @TheNeverposts
      @TheNeverposts 9 лет назад

      ikr

    • @DenysLazarenko
      @DenysLazarenko 8 лет назад +16

      +NMMRSTT indeed.. but as far as i can imagine, making this kind of 3D animation must take absolutely huuuuge amount of time and effort

    • @Wistbacka
      @Wistbacka 5 лет назад +6

      @@DenysLazarenko Yup. It is too time consuming and too costly for anyone to do it, since there is no real economical benefit, and no foundation wants to fund such projects.
      Harvard were about to start a whole department for making science into 3D videos, but funding was cut due to being too expensive and "not enough use" of the material. They produced two amazing videos though....
      Inner Life of the Cell:
      ruclips.net/video/B_zD3NxSsD8/видео.html
      Mitochondria:
      ruclips.net/video/RrS2uROUjK4/видео.html

    • @jeherulislam6903
      @jeherulislam6903 5 лет назад +3

      economy, if there is ROI, people makes bullshit videos too...if there is payback they will certainly make it on larger scale

    • @bionicpenguin5471
      @bionicpenguin5471 3 года назад

      @@Wistbacka i don't think its only cost cause most schools and colleges take hefty fees and give legit bull shit education in return :)

  • @Keod123
    @Keod123 7 лет назад +15

    This video has to be the best one on RUclips for this topic. It manages to pack in all the correct terminology, clearly and concisely, while being accompanied by fantastic animations. I will definitely be recommending this video to my classmates! Thankyou!

  • @ThatGuy09890
    @ThatGuy09890 7 лет назад +18

    This video is amazing! It's so rare that you find a bio animation that has really fancy animations, and also _isn't_ just a rehash of something that's already been done hundreds of times on RUclips before, like DNA replication or something. Thanks for making this so easy to understand!!! :D

  • @caniko2
    @caniko2 8 лет назад +93

    At 3:54, the cleaved mRNAs are degraded because they are missing a poly-A tail or 5'cap, respectively.

    • @George-bq9wv
      @George-bq9wv 6 лет назад +1

      but this modification is related to pre-mRNA , and here it's already modified , i know thats G-cap functions to protects mRNA from being digested by the RNases , but idk what's happened exactly here xD

    • @nirvana571
      @nirvana571 4 года назад

      @@George-bq9wv Can be non-sense mediated mRNA decay

  • @HELLios6
    @HELLios6 8 лет назад +105

    The human body is truly a bio-chemical engineering marvel

    • @pfeliciano4062
      @pfeliciano4062 2 года назад +3

      YES OMG! This is ridiculous, I cant believe this is happening in our bodies, we don't even have to control it it just happens like we have been created by the LORRD my man :') God loves us so he made us perfect!

    • @Thomas-nc9fz
      @Thomas-nc9fz 2 года назад +3

      @@pfeliciano4062 We haven't been created by a lord and our bodies are not perfect in any way.
      God doesn't seem to love the millions of people who die every year with genetic defects so what makes you think he loves you... or even exists in the first place.

    • @shravanbhat7389
      @shravanbhat7389 2 года назад +2

      @@Thomas-nc9fz it probably doesn't exist man
      Even if it exists it probably created the Universe, life formed on its own

    • @smart_viking31
      @smart_viking31 2 года назад

      I believe we humans and life on earth is a biochemical fluke that had occoured billions of years ago

  • @AR-fy2qo
    @AR-fy2qo 3 года назад +7

    The universe is infinite. And even the inside world seems it too. Brings a new meaning to being alive.

  • @mew19forever
    @mew19forever 10 лет назад +44

    Gotta love the fleet footed Motor Protein :) And the Polymerase! Biology is absolutely amazing!

  • @khushbuislam6941
    @khushbuislam6941 8 лет назад +58

    THE animation kind of impairs my hearing ability , cant take them both together

    • @zangetsu6638
      @zangetsu6638 6 лет назад +1

      yeah, it's too fast

    • @Ruba_art_
      @Ruba_art_ 4 года назад

      Yrah I was just taken away by the animation.........

    • @pritiarora9696
      @pritiarora9696 3 года назад

      too many things were goin on .Yea

  • @catherinemisiaszek3426
    @catherinemisiaszek3426 9 месяцев назад

    This is by far the best video explaining this concept, i have been searching endlessly to find good sources on the topic

  • @JorgeRamos-xw6dy
    @JorgeRamos-xw6dy 3 года назад +3

    Very cool. Students are very lucky to have these visuals. Much easier to understand than a school text book. RUclips is more of a learning tool if used correctly.

  • @RFrida
    @RFrida 12 лет назад

    possibly the most entertaining and absorbing scientific animation i've ever seen

  • @krishnarajani3582
    @krishnarajani3582 6 лет назад +2

    That motor protein animation at last was so cute!!

  • @misakesan3498
    @misakesan3498 2 года назад

    This is the prettiest thing I have seen in biology in many many years .. why don't doctors illustrate lectures in such way💔

  • @MO-rn1yx
    @MO-rn1yx 9 месяцев назад +1

    Great animation and amazing explanation, even after 12 years

  • @udyatimalhotra7949
    @udyatimalhotra7949 10 месяцев назад +1

    Excellent video! Explained such difficult concepts with ease and amazing animations. Thankyou!

  • @McCringe
    @McCringe 2 года назад +1

    I cried it's so beautiful

  • @neerajvijay9258
    @neerajvijay9258 4 года назад +3

    The animation and explation is too good any biotechnology student can relate to it easily.. the narration is also very clear .. loved it..

  • @futuremedico3647
    @futuremedico3647 3 года назад +1

    This topic is a complex concept
    And by visualise i understand it better

  • @TurdFurgeson571
    @TurdFurgeson571 5 лет назад

    I'm gonna have to watch this again. I heard nothing the guy was saying the first time through because the animation was so good.

  • @032madhusmitamahakud5
    @032madhusmitamahakud5 4 года назад +2

    It's really amazing that these diverse biological mechanisms are taking place in our body

  • @hank561
    @hank561 Год назад +1

    Thanks, I have bio board exam two days from now. These animations are helping me a lot in revising all the concepts.
    I hope I do good in the exam😃!!

  • @polkastriped8842
    @polkastriped8842 6 лет назад +1

    Super helpful for studying miRNAs and RISC! thanks

  • @luciachp3519
    @luciachp3519 Год назад +1

    Perfect video
    I absolutely adored!

  • @reiniervanherk5649
    @reiniervanherk5649 Год назад +1

    Note. Contrary to a popular believe: Background music disrupts the ability to concentrate, store and remember information. It is esp. a hindrance for asperger personalities, naturally inclined to persue science studies.

  • @bosarama
    @bosarama 13 лет назад

    it's incredible how complex and yet beautifull the way genes acts with each other to answer the body neads. (with body i mean every leaving thing)

  • @lr4189
    @lr4189 8 лет назад +3

    If you got too distracted to understand by the animation try watching it again with your eyes closed and picture the process as she speaks.

  • @PoliticalJohn
    @PoliticalJohn 11 лет назад +1

    Brilliant visualization of the micro-processes inherent in most, if not all, eukaryotic cells. It can reach a lot more people to see spatially what occurs at a near molecular level inside the cell membranes. Bringing the abstract academic into the everyday experience.

  • @henrybserpachumbe6774
    @henrybserpachumbe6774 6 месяцев назад

    12 years ago. Like 12 years ago!!!! Just discovered this topic reading about Haemophilias treatment. Simply amazing

  • @zoyeb100
    @zoyeb100 5 лет назад +1

    Make a Netflix series with this animator ..... the world deserves it.

  • @arv1536
    @arv1536 3 года назад +1

    The animation, the music, the voice.....
    𝙀𝙫𝙚𝙧𝙮𝙩𝙝𝙞𝙣𝙜 𝙞𝙨 𝙟𝙪𝙨𝙩 𝙥𝙚𝙧𝙛𝙚𝙘𝙩.

  • @mohdrehan3256
    @mohdrehan3256 5 месяцев назад

    The animation is mind blowing

  • @yangsi3389
    @yangsi3389 3 года назад +1

    Amazing description.... Thank you soooo much.

  • @asmaahassan1802
    @asmaahassan1802 8 лет назад +2

    very professional and easy way to explain RNAi

  • @francestorreysirdevan4774
    @francestorreysirdevan4774 5 лет назад

    Animation and explanation (but animation OMG) were STUPENDOUS 👏👏👏

  • @amritasriv87
    @amritasriv87 6 лет назад +1

    learning has become fascinating...thanks to such videos

  • @smiley235
    @smiley235 11 лет назад

    I see videos like this and contemplate it with other thoughts such as neural networks and everything else resiliently working together which leaves me totally dumbfounded about how I cant even get close to grasping the complexity of living organisms. Mind blown!

  • @benblack742
    @benblack742 5 лет назад +5

    this music slaps, easily the best part of the video

  • @pridhichahal708
    @pridhichahal708 3 года назад +1

    One of the best things ....I have ever seen
    Thanks a lot !!!!!

  • @DD-rc7wi
    @DD-rc7wi 3 года назад +1

    dayum. whatte video. well done yall!

  • @martinbakht2214
    @martinbakht2214 10 лет назад +1

    The graphics are cool!

  • @adamroth438
    @adamroth438 10 лет назад +1

    Great animation!

  • @Teghead
    @Teghead 13 лет назад +2

    I love the way it zooma out as though leaving a little solar system (music helps),

  • @shreyasichandra7563
    @shreyasichandra7563 3 года назад +1

    What an amazing video... I can watch it again and again 😍

  • @franer3428
    @franer3428 4 года назад

    couldnt understand the concept but I loved it

  • @KrishnamKumawat
    @KrishnamKumawat 9 лет назад +14

    Oh. My. God! Love this animation!!

  • @zangetsu6638
    @zangetsu6638 6 лет назад +54

    please slow down. it takes time to digest all this.

    • @Biocreator
      @Biocreator 3 года назад

      you can slow your playback speed

  • @marianamurphy3118
    @marianamurphy3118 10 лет назад +1

    Animation helped out immensely !! Finally, It makes sense!

  • @nadeemahmed4029
    @nadeemahmed4029 4 года назад

    Best animation ever seen💖💖💖💖

  • @ShakespeareCafe
    @ShakespeareCafe 6 лет назад +1

    Stunning graphics. I'm currently reading Molecular Biology of the Gene 7 Ed chapter on Regulatory RNAs. Fascinating stuff.

  • @Nufsin22
    @Nufsin22 11 лет назад +2

    This is an amazingly structured and educational video. None of the other sites I visited made it easier for me to understand than this. However, one thing to consider is to show the complicated technical terms in text when used. That way, it's easier to look words up if you don't understand them. Oh and by the way, I liked the background music. It soothed me.

  • @carbonbased7291
    @carbonbased7291 13 лет назад +1

    Great animations and explaining!

  • @abdullahijamiu8617
    @abdullahijamiu8617 5 лет назад

    Nice animation and presentation

  • @abhinavkumar3026
    @abhinavkumar3026 6 лет назад

    its the best video to understand rnai mechanism

  • @hemakabir8736
    @hemakabir8736 3 года назад

    Thank you Pranav Pundarik Sir

  • @hendmakky5664
    @hendmakky5664 4 года назад +1

    loved this. finally RNA Interference mechanism is going to settle in my mind.

  • @futuremedico3647
    @futuremedico3647 3 года назад +1

    Thank you for wonderful explanation

  • @snehanjalimohanty5030
    @snehanjalimohanty5030 5 лет назад

    So nice video ..cleared many confusions.

  • @Ta73PT
    @Ta73PT 3 года назад +1

    Thank you very much for creating this animation and making this video available for free. I love it ♥️

  • @simranjoharle4220
    @simranjoharle4220 7 лет назад

    The animation is so indulging.......love it....really helped.

  • @AA-gl1dr
    @AA-gl1dr 3 года назад +1

    Amazing

  • @varshavidya5693
    @varshavidya5693 Год назад

    It is such a sweet and beautiful explanation. Thank you ☺

  • @aashimapopli1505
    @aashimapopli1505 5 лет назад

    My professor was unable to explain this even in 2 hours which you told in just 5 minutes.thank you

  • @aeneas116116
    @aeneas116116 10 лет назад +9

    Very interesting, it appears to have the same plot as that popular tv show LOST

  • @Dr.shaziya_khan
    @Dr.shaziya_khan 5 лет назад

    i have no words to descibe it ......amezing....

  • @terezakrivankova4687
    @terezakrivankova4687 5 лет назад

    So great animation - simple and educative. People who try to learn this from books don’t memorise it so good than from this video animation. Thanks for that, great job! 🙏

  • @808Chrissy808
    @808Chrissy808 12 лет назад +2

    What a fine piece of animation :D

  • @ConcealRise
    @ConcealRise 13 лет назад

    @there4able The "walking" molecule is called kinesin. It's transporting a vesicle of some sort along a microtubule, which is that brown thread.

  • @karinakapoor4501
    @karinakapoor4501 3 года назад

    couldnt focus. on what she was saying because the video was so satisfying

  • @crocketmeow
    @crocketmeow 7 лет назад

    I really like the video graphic animations, but white text with the key terms such as DROSHA/DRGC8/DICER/AGO/RISC/ETC would have been quite helpful.

  • @jhelumchaubal396
    @jhelumchaubal396 5 лет назад

    Amazing video/animation.

  • @matrixcodebreak
    @matrixcodebreak 11 лет назад

    what a video...Mind blowing

  • @toughsuga2
    @toughsuga2 13 лет назад

    Great animation.

  • @unnatisingh6140
    @unnatisingh6140 6 лет назад

    Beautifully presented and magnificently explained

  • @ms.artemis9959
    @ms.artemis9959 7 лет назад +2

    Instead of reading, this video make my comprehension better... Thank you Nature :)

  • @adayahisrael7224
    @adayahisrael7224 2 года назад +1

    So this is what is happening to our food? I read an article talking about this very thing. It is used in place of pesticides. My question is what are the long term effects this will have on the human body?

  • @eantonio5939
    @eantonio5939 10 лет назад +3

    Very well done video! This video displays many other accurate cell functions and gives a great explanation. Great job!

  • @alugaddasudhavani3884
    @alugaddasudhavani3884 6 лет назад

    The animation is very good

  • @rajsadhukhan5076
    @rajsadhukhan5076 4 года назад

    Awsome way of explaining... thanks...

  • @karthikraghavendran9643
    @karthikraghavendran9643 9 лет назад

    the video is simply incredible..RNAi has a major role to play in curing of many diseases but what are the technical difficulties in introducing RNAi into the cells?Can anyone help me with this question?

  • @ArizonaBob
    @ArizonaBob 13 лет назад +1

    Wow! Excellent video!!! Thumbs up!

  • @Lurker404
    @Lurker404 10 лет назад +20

    Holy shit body can you not be so complicated? You're making my exams a real bitch

  • @dina5115
    @dina5115 4 года назад

    Beautiful explanation and video!!

  • @AJ-kw1op
    @AJ-kw1op 2 года назад +1

    Pwoliyeeeee..... ❤️

  • @peacockanus
    @peacockanus 11 лет назад

    Kinesins are so fun to watch! They're mechanistically cool too ofc.

  • @MusicCrazyLover23
    @MusicCrazyLover23 8 лет назад +11

    This is the best animation on the topic :p

  • @SalSabila-le3vo
    @SalSabila-le3vo Год назад

    Wow this made my concept super clear. thank you so much

    • @souha3233
      @souha3233 Год назад

      Just a Q
      Does the RISC cut the RNA? So that it stops translation? Or it prevents ribosomes from moving to continue the production of the protein

  • @RahulMPrathap
    @RahulMPrathap 5 лет назад +1

    The animation is well made. It looks spooky at first, t helped me understand easily.

  • @hemanirjeshverma3606
    @hemanirjeshverma3606 2 года назад

    Amazing accurate animation... kudos.. plz bring more such videos on CRISPR , and other emerging tech

  • @FaisalAhmedMoinuddin
    @FaisalAhmedMoinuddin 11 лет назад +1

    Brilliantly animated.
    Keep up the awesome work.

  • @indirasrinivas2511
    @indirasrinivas2511 5 лет назад

    Wow awesome video thank you

  • @vuhienanh3787
    @vuhienanh3787 6 лет назад

    Oh such a beautiful video!

  • @kiplimosimon1429
    @kiplimosimon1429 Год назад

    Good work. Very informative.

  • @sabbaninarsaiah6855
    @sabbaninarsaiah6855 4 года назад +1

    Kiirrrrakkkkkkk🥰🥰🥰😘
    Superb mam tq so much

  • @Bramble451
    @Bramble451 10 лет назад +14

    Great graphics. I'm sure someone more knowledgeable than me can make sense of it. :(