How Cyanide Poisoning Works

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  • Опубликовано: 10 июн 2024
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    cited sources:
    en.wikipedia.org/wiki/Cyanide...
    history.com
    • Module 3B - Cyanide Ov...
    www.compoundchem.com/2016/07/...
    en.wikipedia.org/wiki/Cyanide
    books.google.com/books
    en.wikipedia.org/wiki/Mole_(unit)
    www.omnicalculator.com/chemis...
    www.calculatorsoup.com/calcul...
    en.wikipedia.org/wiki/Names_o...
    www.ncbi.nlm.nih.gov/pmc/arti...
    CrystaLean
    CFD 19
    Dastino

Комментарии • 984

  • @darkscienceyt
    @darkscienceyt  2 года назад +83

    🎉 Signup for your FREE trial to Wondrium here: ow.ly/zEAS30rZakG 🎉

    • @garyday2447
      @garyday2447 2 года назад +1

      So how do I reverse the damage

    • @richardbirks
      @richardbirks 2 года назад

      How Cyanide poisoning works for idiots:
      1. Ingest cyanide.
      2. You're poisoned.
      3. You die.
      Did I miss anything?

    • @Mistybrooks84
      @Mistybrooks84 Год назад

      They are signed into my account.
      The victim slows down to a coma... Blah blah blah.
      8th century.llk

    • @Westbankfireman
      @Westbankfireman Год назад +1

      nah

    • @AshtonDv
      @AshtonDv Год назад +1

      No.

  • @Xplayer007
    @Xplayer007 2 года назад +3559

    From biology I do remember that the mitochondria is the powerhouse of the cell.

  • @Dom_Maretti
    @Dom_Maretti 2 года назад +991

    I got stoned for the first time in university, and expecting "munchies" was surprised that I felt only mildly hungry. I had a 5 lb bag of raw almonds which I would grab a small handful of every day for a quick snack before my earliest class...and by the time I tried the pot, I was down to about 3 lbs. Before I realized it, I had eaten three full pounds of raw almonds in one sitting...then proceeded to have 2 full days of flu-like symptoms and increased propensity for asthma attacks. I thought I was just sensitive to pot, and decided against using again...until I described what I experienced to a med student on the campus, who basically immediately told me that I had suffered mild cyanide poisoning from the raw almonds...which contain small amounts of a chemical called amygdalin, which our body processes into HCN. Most people don't eat 3 lbs of raw sweet almonds in one sitting, so the trace amounts of amygdalin isn't deemed to be too much of an issue and isn't mentioned on the bag or anything. TL;DR: Don't eat multiple pounds of raw almonds in one sitting.

    • @jimvick8397
      @jimvick8397 2 года назад +173

      Since we are on the topic... Don't eat an entire 2lb bag of Costco dried Apricots all at once... I did a big hike on a cold rainy day, on the way home, I realized I had the bag of dried Apricots flopping around in my rear floorboard (apparently they slid off the top of my Costco load the day before). Anyways, I had a few and they were delicious, then I really laid into them and finished the bag in less than 10 minutes... I woke up the next day with a pressure in all of my bowels that was beyond anything I've ever experienced, and I was cramping from my chest to my butthole... I ran to the bathroom and threw my buttcheeks on the pot as the explosion happened...
      At this point force and pressure of the evacuation caused the chunks to shoot back up my butt crack, up the wall, and across the ceiling, as I stood up to relieve the pressure, there was a secondary explosion... From working out of the bathtub and using all of the towels, it took me 3 hours to clean and sanitize all the shit that had exploded all over the bathroom... If an MD can explain what happened, I would love to know...

    • @exan8825
      @exan8825 2 года назад +97

      @@jimvick8397 holy shit.

    • @LordBLB
      @LordBLB 2 года назад +52

      @@exan8825 Literally! lol

    • @girl-di3nn
      @girl-di3nn 2 года назад +19

      Also also don’t eat a bunch of donut holes in one sitting either you will get food poisoning and that is an experience all by itself

    • @AmericanPatriot-cw9xe
      @AmericanPatriot-cw9xe 2 года назад +38

      when I was trucking I kept smoked almonds with me at all times, I loved to snack on it and trail mix for a easy meal n energy, I started getting severe cramps after I left home n was on the road a few days, then I remembered somehow that almonds either has trace cyanide or resembles it, I stopped eating all together n my health issues got better, but i really loved almonds, but its crazy how something promoted as a healthy snack can hurt or kill you over time

  • @panitofisial2270
    @panitofisial2270 2 года назад +758

    I just finished my metabolism exam, and after learning that at school feels so good to know what's happening here. Also, you make everything so easy to understand and make it interesting to learn.

    • @heartcomedy5
      @heartcomedy5 2 года назад +4

      Same bro

    • @hubguy
      @hubguy 2 года назад +3

      Easy way to tell that someone understand what they’re talking about. When they can do it in a way that others can understand

    • @toserveman9265
      @toserveman9265 5 месяцев назад

      Are you more indoctrinated or educated?

  • @desmondmurphy449
    @desmondmurphy449 2 года назад +355

    I'm a jeweler and I've worked with cyanide based plating solutions for years. I just don't drink it or mix it with acid. I remember my old boss telling me that the amount of cyanide you could pile on your little finger nail could kill you easily. I have a healthy respect for the stuff.

    • @emilyraymond8544
      @emilyraymond8544 Год назад +12

      glad you don’t drink it! lmao?

    • @brandonbrinegar5316
      @brandonbrinegar5316 11 месяцев назад +10

      There's sodium cyanide and potassium cyanide. Potassium cyanide is more poisonous whereas sodium cyanide is used to work with metals and the like,,,but still toxic.

    • @pluuvia1553
      @pluuvia1553 4 месяца назад

      ​@@brandonbrinegar5316i work in electroplating and we use a lot more potassium cyaniye than sodium cyanide. especially for silver plating solutions

  • @jagslab
    @jagslab 2 года назад +367

    More info about cyanide:
    As mentioned, amyl Nitrate (the cure mentioned in the video) converts hemoglobin into methemoglobin. Hemoglobin is made up of Ferrous (iron with a +2 positive charge), but methemoglobin is made up of Ferric (iron with a +3 positive charge). Cyanide does not bind to ferrous, but it does bind to ferric. Therefore, amyl nitrate will cause much of the cyanide to bind to your blood cells, which has a lot of iron. Each blood cell contains 300 million hemoglobin and each hemoglobin has 4 iron atoms. Therefore, a blood cel can bind to 1.2 billion molecules of cyanide. Interestingly, there is also a medical condition known as methemoglobinemia, in which people have an abnormally high amount of methemoglobin (this causes them to be more resistant to cyanide poisoning).
    Also, as mentioned above, ferric has a 3+ charge which makes it capable of binding to cyanide. Another treatment for cyanide poisoning is hydroxycobalamin-this molecule is basically a form of vitamin B12. What makes this molecule interesting is that it has a cobalt atom with a 3+ charge (just like ferric). So, this molecule is also given as a treatment for cyanide poisoning because cyanide can bind to this molecule just like it can bind to ferric in the methemoglobin of blood cell. When hydroxycobalamin binds to cyanide, it turns into cyanocobalamin. This is another form of Vitamin B12-completely harmless. It’ll get used by your body or it will be excreted through urination.

    • @Dantick09
      @Dantick09 2 года назад +12

      Very cool, so if the cyanide dose is too high the antidote is ineffective?

    • @SuperShakirawakawaka
      @SuperShakirawakawaka 2 года назад +17

      How did you learn all this?? is it part of your career?

    • @HuyNgouc-nl5tb
      @HuyNgouc-nl5tb 2 года назад +1

      @@Dantick09 when u have way too much poisons it’s basically lethal

    • @siblinguploads7326
      @siblinguploads7326 2 года назад +9

      @@HuyNgouc-nl5tb too much of anything is lethal

    • @SV33381
      @SV33381 2 года назад +4

      Has she stopped talking yet? 😴😴😴😴😴😴😴😴😴😴😴😴😴😴😴😴😴😴😴😴😴😴

  • @chrisalexthomas
    @chrisalexthomas 2 года назад +172

    This video singlehandedly explained a puzzle I was wondering about, how can such a tiny quantity of something kill you. It's because I didn't realise how many cells in the body there are and how many molecules go into a mole of something. Thanks for explaining! Now I understand why, it's such a staggeringly large number that even at such a low quantity, there is an overwhelmingly large quantity of the something that kills you.

  • @javier.a.vargas
    @javier.a.vargas 2 года назад +72

    i ve had various college chemistry courses including organic chemistry and yet i didn't knew how simple cyanide poisoning worked. this felt like it being spoon fed directly to my brain. Great content!

  • @emerychandler
    @emerychandler 2 года назад +33

    Had this guy from high school (we weren’t close but I knew him well) who committed suicide by creating and stealing hydrogen cyanide from his university chemistry laboratory. He was gifted and his death was very tragic. Low key it’s interesting to see how it works, wish it wasn’t a thing though.

    • @TonyDanza4Lyfe
      @TonyDanza4Lyfe 2 года назад +10

      I don't understand why someone with options would choose cyanide. It just seems like one of the worst ways to go

    • @emerychandler
      @emerychandler 2 года назад +9

      @@TonyDanza4Lyfe I vaguely recall him making a joke about it a time or two in high school. May have been psychological. We weren’t friends, but I’ve had a lot of respect for him. He was talented, smart, and funny.

    • @reynaldoflores4522
      @reynaldoflores4522 2 года назад

      Even in death he had to show-off by creating his own poison.
      Simpler and cheaper to just buy a few sleeping pills at the corner drugstore.

    • @seraphina985
      @seraphina985 Год назад +6

      @@TonyDanza4Lyfe To be fair most people could probably acquire arguably one of the better ones fairly easily with a little effort. Opioids are probably one of the gentlest method if one is that way inclined, initial effects of a lethal dose begin with a brief period of intense relaxation and euphoria followed by unconsciousness and death from respiratory suppression. But the patient loses consciousness prior to the effects of the respiratory depression kicking in so they just drift off never to awaken again. There is a reason why they are usually the drugs of choice for euthanasia by both veterinarians and doctors in jurisdictions where human euthanasia is legal. It is pretty much the gentlest way to accomplish the result with a single drug as it in effect happens to function as a relaxant and anaesthetic prior to actually doing the deed.

    • @vice.nor.virtue
      @vice.nor.virtue 11 месяцев назад +1

      @@seraphina985 Right?! If I had to choose between these two ways of exiting life I know which one I would choose.

  • @JJones-cl4dm
    @JJones-cl4dm 2 года назад +55

    you broke it down way more than I expected and I appreciate that. good content

    • @darkscienceyt
      @darkscienceyt  2 года назад +5

      no problem, thanks!

    • @dororo2597
      @dororo2597 11 месяцев назад

      @@darkscienceyt hey pals, your videos are good with nifty explication and coherent with graphics you offer
      But if you put any hecking music, i'll forsaken you, discern this, that'll perturb the Knowledge you want to convey

  • @Jayderzomb
    @Jayderzomb 2 года назад +48

    It’s just mind blowing to me that such a cool and informative video gets views so slowly, seriously this stuff is too interesting to me

    • @peterzimmerman1114
      @peterzimmerman1114 2 года назад +5

      Because it's kind of a sensitive subject and most people don't want to touch it, or show interest, I figured it might be a good idea to know more about possible health hazards.

    • @johndean4727
      @johndean4727 Год назад +1

      @@peterzimmerman1114 im obsessesd with it.

  • @wildsmooth9201
    @wildsmooth9201 2 года назад +31

    My friends grandfather was a trapper that would use Cyanide in traps to kill coyotes going after his livestock. My friend and I watched his dog die after getting in one of the cyanide traps while walking in the woods. That dog died in about 1 minute.

    • @elultimo102
      @elultimo102 2 года назад +11

      I wanted to make some cyanide-based rat poison. I don't want them to suffer, just expire quickly. (A company employee told me they deliberately make it "slow kill," in the event your child or pet ingests it; this allows time to get to medical help before it's too late).

    • @krislarsen6546
      @krislarsen6546 2 года назад +2

      @@elultimo102 Makes sense..... Imagine if someone got a hold of that chemical and it wasn't slowed down but nearly instant or the minute instant anyways it could be used as a terrorist weapon...... Very good move on that company's part

  • @JAOResnik
    @JAOResnik 2 года назад +25

    I like how the antidote for cyanide is itself a poison

    • @KuraSourTakanHour
      @KuraSourTakanHour 2 года назад +2

      We poison the poison, its the only way 😂

    • @MrErichonda30
      @MrErichonda30 Год назад +1

      Think it's popular in the gay community

    • @ravenID429
      @ravenID429 5 месяцев назад +2

      @@MrErichonda30Cyanide???

    • @pluuvia1553
      @pluuvia1553 4 месяца назад

      ​@@ravenID429no i think what he meant was that you weren't allowed to give the antidote to a gay person, because if they have remains of a drug that is or used to be very popular in gay clubs in their blood, the antidote will kill them. at least someone i work with told me that and i work in electroplating, where we use a lot of cyanide for solutions. but idk it might be wrong

    • @larnacaLCA
      @larnacaLCA 4 месяца назад

      @@ravenID429 nope, not the Cyanide, the antidote is commonly sold in Sex shops or online it's street name it's Poppers as it gives a short lived rush as inhaled. Truly interesting that while injected it could save your life if poisoned as in Agata Cristies book
      📙😎💅

  • @gregoryross.303
    @gregoryross.303 2 года назад +35

    As a professional opossum hunter for many years in New Zealand, I was licensed to use potassium cyanide paste as a rodent-control poison. Virtually all opossum hunters in New Zealand still use this paste, and as part of the legal requirements for an operator using cyanide, you must always carry a few amyl nitrite-filled glass capsules in your pocket in case you accidentally ingest or inhale some cyanide. You were to break open the glass capsule and deeply inhale the amyl nitrite fumes from the liquid. Fortunately I never had to do that during my years of wandering through remote alpine forest while laying out lines of cyanide baits for opossums. One bait the size of an pea, can kill several opossums, and finding four dead opossums around one bait is common. The poison kills virtually instantly and the opossum does not get much chance to wander away from the bait. Cyanide is a very efficient and inexpensive way to control the millions of non-native opossums (these are actually Australian brush-tailed opossums from Australia) which were liberated in New Zealand in the 1800s in the days when conservation was not heard of. These opossums now live in New Zealand in large numbers and do much damage to native species and forests there. There is, from time to time, also a lucrative market for opossum furs from New Zealand. I appreciate this video, thank you, as it has refreshed my knowledge of cyanide, which I have not used since 1981.

    • @alexstrauss5264
      @alexstrauss5264 2 года назад +6

      what an interesting profession.

    • @AmericanPatriot-cw9xe
      @AmericanPatriot-cw9xe 2 года назад +2

      Be careful here in the USA I had a very large opossum that had rabies most likely charge at me full speed as it came up over a small rise I was deep in the woods of west virginia n hunting a old hollowed out Beech tree for squirrel one evening, that creature saw me sitting there and came running at me full speed snapping his teeth and was a running full speed fast towards me I had a spilt second to realise it was coming for me, and had to shoot it right as itt got almost to me feet, the dang thing weighed close to 4o lbs, I was just 13 i took it home to show my dad what happened, n he was so pissed i shot something i wasn't going to eat, he told me if i ever shot another n brought it home I would have to eat it, man dad was old school, n thats the way to be, but not when one charges u like that! I doubt dad believed me, i shot everyone of them in the woods i ran across after that, it was fun to hunt in front of the house n fish the river behind us, those 3 yrs were the funnest times with some of the best salt of the earth people you would ever hope to meet, it took me a couple yrs to be fully accepted there, but once they know u n can trust you, its the best place to grow up

    • @marc-andreservant201
      @marc-andreservant201 2 года назад +1

      Nowadays the preferred antidote is hydroxocobalamin, which is entirely non-toxic but unfortunately has to be given by injection. It reacts with cyanide to form water and vitamin B12, which you pee out. The cobalt atom in vitamin B12 holds on to cyanide more strongly than the enzymes in your mitochondria.

    • @gregoryross.303
      @gregoryross.303 2 года назад +1

      @@marc-andreservant201 Interesting. I wonder if New Zealand's large number of cyanide-using rodent-controllers have been upgraded to this new antidote, and now carry the antidote and a syringe with them, instead of the glass amyl nitrate capsules. You would have to act VERY quickly to get the injection into you if you ingested cyanide, as it acts so quickly. I passed my poisons exams in New Zealand in 1970, and then was entitled to buy and use cyanide. I have not used it since 1981, my final season of poisoning rodents with cyanide. My cyanide license has probably long-ago become invalid, but, when I passed the exams in 1970 it was supposedly good for life. In 1983/84 I worked for the New Zealand Forest Service poisoning possums in Westland, but that was all done with 1080 poison and is still the case today.

    • @plaguedoctorowl
      @plaguedoctorowl 2 года назад +3

      @@AmericanPatriot-cw9xe That's interesting since opossums are mostly immune to rabies

  • @janeanet
    @janeanet 2 года назад +41

    had to do a case study over the Tylenol poisoning for my anatomy class, this helped a lot thank you!

    • @aloo_ka_paratha
      @aloo_ka_paratha 11 месяцев назад

      Hi ! I want to contact you how can i?

  • @jimcrawford297
    @jimcrawford297 2 года назад +12

    I always find it nuts how life is just chemical machinery. I mean, I know it's obvious but at the same time the chain of events is mindblowingly simple.

  • @allanrichardson9081
    @allanrichardson9081 Год назад +11

    Another antidote is the reducing agent sodium thiosulfate (known to film photographers as “hypo”), and also used in hair salons to break the disulfide bonds between amino acid chains in hair so that the hair can be curled or straightened, then another compound rebuilds the bonds.
    Also, there are certain species of mammals that are immune to cyanide. How do they accomplish this?

  • @jc_da_killa7132
    @jc_da_killa7132 2 года назад +12

    Never been to this channel before. I’m really impressed with how in-depth he’s explanation went. Really interesting stuff.

  • @monkeybusiness673
    @monkeybusiness673 2 года назад +10

    That is hands-down the coolest science video I've seen in years. Thank you, and keep up the great work.

  • @shikasan3337
    @shikasan3337 5 месяцев назад +5

    nothing like starting off an 8 minute video with a minute long ad read

  • @YukonDemon
    @YukonDemon 2 года назад +7

    All the interesting science and learning stuff aside, watching Joffrey Baratheon take his last wretched miserable breaths was one of the most satisfying moments to ever grace my television screen.

  • @apantisit
    @apantisit 2 года назад +9

    I love your way of teaching very much! Very precise and straight to the point.

  • @matiaskuperman2890
    @matiaskuperman2890 2 года назад +4

    i completely LOVE your videos, please please please don't make them stop

  • @hiimgamerspruzzino5804
    @hiimgamerspruzzino5804 2 года назад +5

    Wow, you explained everything in such a simple and easy way, i usually hate chemistry because i always had trouble to understand it, but this video was so clear. Good job

  • @tommunyon2874
    @tommunyon2874 2 года назад +7

    This is so enlightening. I was given an entirely, non- biochemistry, different explanation in undergraduate inorganic chemistry decades ago. I was told that the CN was a powerful ligand that bonded to the hemoglobin and caused suffocation.

    • @yousefhaidar885
      @yousefhaidar885 2 года назад

      I was actually surprised that there was another explanation. Always thought cyanide would bind to to hemoglobin kinda like carbon monoxide. Like both can form pi back bonding to iron(II)

  • @r_ramendump9681
    @r_ramendump9681 Год назад +7

    I stopped studying chemistry at 16 and moved onto engineering in polytechnic and I must say, the guy that figured out the antidote to cyanide must be smart as hell

  • @Cloro_Sodio
    @Cloro_Sodio 11 месяцев назад +1

    This is a really good explanation, not only you made the tossic mechanism clear, but you also brought the point of view from a number perspective thet I wouldn't consider, you've really done a good job with this video 👍

  • @tc-3
    @tc-3 2 года назад +81

    I really enjoy your videos. Super interesting topics presented in easily comprehensible way. Keep up the great work!

  • @Mr.Boyo13
    @Mr.Boyo13 2 года назад +8

    New video? YES I need to feed my cravings for new informational videos

  • @HenrikMyrhaug
    @HenrikMyrhaug 2 года назад +4

    That Chevy Corvette part was hillarious!

  • @sagarshrestha5800
    @sagarshrestha5800 2 года назад +1

    Lastly giving a short revision is really helpful.Thank you for that.

  • @likklej8
    @likklej8 2 года назад +16

    In the 70s I worked in an automobile component plant. Chemicals used in metal hardening produced Hydrogen Cyanide myself and a work colleague were exposed. I spent a day in hospital.

  • @cascadesouthernmodeltrains7547
    @cascadesouthernmodeltrains7547 2 года назад +3

    I am a former autobody painter. There is a chemical in the paints that is called isocyanates which will have the same effect on the human body as cyanide does. The chemical is a very close relative to cyanide. The molecule promotes adhesion and is found also in things like Super glue, and high quality chip resistant nail polish. Few people are sensitive to this chemical, actually we are exposed to it all the time but most will never feel it. I on the other hand, and people who are sensitive to it will get tremors, difficulty breathing and a few other issues that depend on the person.

  • @peterb4926
    @peterb4926 2 года назад +5

    This is well done with the exception of the treatment section which is not correct by today’s standard. Today the ambulance paramedics and emergency room physicians use intravenous hydroxycobalamin or cobinamide. Amyl nitrite, sodium thiosulfate and sodium nitrite are only used in very rare scenarios.

  • @GummyBearWA
    @GummyBearWA 2 года назад +4

    Who would have thought "poppers" could be an antidote for Cyanide.

  • @Nathaniel64
    @Nathaniel64 20 дней назад +1

    I was working on a paper while eating cherrys. I tend to chew on things when I am stressed. I ended chewing on the pits. I completely blacked out soon and I could not move any part of my body. I woke up two days later and my lungs felt like sandbags. I immediately opened a window thinking it was co2. The sense of doom scared me in ways I don’t think even think I can completely understand. Thankfully I got help. I definitely don’t like cherries now.

  • @itzedric
    @itzedric 2 года назад +5

    I’m back here after 2 years, when your videos got sued and I commented, my life has been much much more busier now so yeah, still love the vids, I can understand how much time it takes for one vid but keep it up, this is very understandable and clearer :)

    • @darkscienceyt
      @darkscienceyt  2 года назад +6

      Hey, thanks for sticking around and understanding! That was a very dark time for me, and I was close to giving up. I'm thankful for viewers/subs like you!

    • @itzedric
      @itzedric 2 года назад +3

      @@darkscienceyt thanks, keep up the hard work 👍

  • @Bigvs.Dickvs
    @Bigvs.Dickvs 2 года назад +10

    Now you made me remember one of my favorite drinks, bitter almond liquor with a bit of a lemon squeeze.
    Bitter almonds contain Cyanide, I believe less than 20 really bitter ones can poison you with a letal dose. But that's safe on that liquor.
    How didn't I remember this during lockdowns?
    Well, I guess I now have a drink for the winter. Thanks!!

    • @andy-the-gardener
      @andy-the-gardener 2 года назад

      sounds like 160 billion bitter almonds could solve the planets problem in one fell swoop. hmm

  • @donaldhoot7741
    @donaldhoot7741 2 года назад +6

    Great, now if me wife passes away "they" are going to see I watched a cyanide video! lol

    • @2msvalkyrie529
      @2msvalkyrie529 2 года назад +2

      As long as you don't Google : How to dispose of a dead body .? "
      As some idiots have done . ( Unsurprisingly they are now incarcerated ! )

  • @RPJSciencehistorymathematics
    @RPJSciencehistorymathematics 3 месяца назад +1

    Not only lactic acid is created during anaerobic metabolism. Even alcohol and carbon dioxide. But in muscles during heavy exercise, lactic acid is created and accumulates to cause cramping. Even Co2 is generated when we use small amounts of oxygen

  • @JAYZ999
    @JAYZ999 2 года назад +4

    The COX enzyme in the electron transport chain is also commonly called complex IV (4). Just thought I should add this given that I’ve studied it today lol.

  • @evelyntromp789
    @evelyntromp789 2 года назад +5

    You are a really good teacher. Thank you for the video!

  • @somaday2595
    @somaday2595 2 года назад +1

    @1:57 - Minor point - The acrylo in acryloitrile is pronounced uh - krillo (short i) - nitrile (long i)
    Et cetera - Cytochrome P450, sodium thiosulfate, vitamin B12

  • @coreinnu
    @coreinnu 2 года назад +11

    Lessons at school would be much more interesting to enhance if teachers let students dive into facts from this channel.

  • @LekkerRandom
    @LekkerRandom Год назад +4

    Wow, didn’t even knew it back then, but I’ve probably had a cyanide poisoning in Thailand bc of cassava…

  • @tomasallende9583
    @tomasallende9583 2 года назад +3

    Now hydroxocobalamin is more commonly used as an antidote since it directly reacts with cyanide to form cyanocobalamin and it's far less toxic than amyl nitrite.

  • @andrejspecht8217
    @andrejspecht8217 2 года назад +5

    Here's a question: When you print ABS on a FDM 3D printer - you heat up the ABS filament. I know the burning ABS releases hydrogen cyanide gas.
    But will it happen as well, when you heat it up to 200 degrees Celsius? (392 Fahrenheit)
    Also, RIP Geoffrey, he didn't activated Windows.

  • @UltimaJC
    @UltimaJC Год назад +1

    Bless you for putting Joffrey's death scene in there. I needed something funny today.

  • @211inprogress
    @211inprogress 2 года назад +6

    Thanks, just Reminded me to arrange that dinner party. 🍽️💀

  • @TwinFlyDSW
    @TwinFlyDSW 2 года назад +3

    Just a thought. Seeing how Cyanide stops the production of ATP, is it not possible to synthesize ATP artificially or a substitute that could be administered along with Amyl Nitrite?

  • @kirlyuu
    @kirlyuu Год назад +2

    Can 50mg cyanide be lethal if medical treatment isnt received at all?

  • @Morlev44
    @Morlev44 Год назад +1

    I can't believe mole made it to SI unit system. It would fit right into imperial system from what I can see about it.

  • @tomielectro8235
    @tomielectro8235 2 года назад +4

    At 7:10 there is air in the syringe? I mean that wouldnt kill someone?

  • @cprendon3
    @cprendon3 2 года назад +57

    It would have been nice to include the timeline of how a lethal dose of cyanide oral route effects the body and when death occurs.

    • @mityaboy4639
      @mityaboy4639 2 года назад +5

      exactly- because there are these (mis) conceptions that you just crack open the cyanide pill and 2 seconds later you are dead… (used in many movies) … yes we know movies are not the real thing but there isnt just any counter information available as readily as it should be.
      (for example if there is a cure and can be administered into the bloodstream then surely the ‘you have two seconds to live’ is not the case)
      but still would be good to know what are the timescales to get help) :)
      good video otherwise:)

    • @somaday2595
      @somaday2595 2 года назад +3

      @@mityaboy4639 Inhalation - ~ 2 minutes.

    • @julybailey2326
      @julybailey2326 Год назад +2

      @@mityaboy4639
      Cyanide pill orally 2-5 minutes.

    • @Keicarlover69
      @Keicarlover69 10 месяцев назад +1

      @@julybailey2326what about two or more pills ? Does it fasten the process or just make the effects worse

    • @swarajkar3086
      @swarajkar3086 4 месяца назад

      100mg ingestion will kill you in an hour.

  • @SV7-2100
    @SV7-2100 2 года назад +1

    I'm happy to see a video blow up your channel is very underrated

  • @ivanvalverde7018
    @ivanvalverde7018 2 года назад +2

    Thank you! Corvette example was amazing!

  • @chapiit08
    @chapiit08 2 года назад +8

    Ingested in the right amount it can render a person permanently blind almost instantly. I know of a case where the victim inadvertently drank a glass of cyanide solution in the belief that it was drinking water at a jewelry manufacturing workshop and went completely blind in no time.

  • @sayncevizoglu1057
    @sayncevizoglu1057 2 года назад +5

    Im not a sadistic person but Joffrey's death satisfied me like nothing else did .

  • @sciencenerd7639
    @sciencenerd7639 Год назад +2

    At 2:57 he said that cytochrome c oxidase is also called the cox enzyme, however the cox enzyme is actually cyclooxygenase, which makes prostaglandins and has nothing to do with electron transport.
    Still a fantastic video in any case!

  • @AdamB12
    @AdamB12 2 года назад +1

    The fire at The Station club in Rhode Island..there was soundproofing foam where the drummer sits on the stage. When it burned it produced hydrogen cyanide gas in the smoke, many patrons that night lost their lives to the inhalation of that toxic gas.

  • @Andro-_
    @Andro-_ 2 года назад +3

    Wow this is the first time I understood something without ever questioning

  • @ahlalkubur
    @ahlalkubur 2 года назад +4

    "Mitochondria is the powerhouse of the cell"
    Cyanide Poisoning: "Say SIKE !!!"

  • @untilifeelnothing_
    @untilifeelnothing_ 2 года назад +2

    great video and your explanation of how it works was really helpful and easy to understand.
    how long does a person have after ingesting cyanide to get the antidote? it seems to take effect very quickly.

  • @wardibald
    @wardibald 2 года назад +2

    More people are getting awed by how big the universe really is, thanks to spectacular new astronomic discoveries. And that's great, but not yet enough realise the universe's scaling goes the other way too, into smaller quantities. And the orders of magnitude involved are even more awe inspiring of you think about it.
    E.g. there are more molecules in a glass of water than the current estimate of the number of stars in the known universe.
    Videos like this one are a great way of improving the visibility of this. You have no idea how interesting chemistry is until you really start studying it.

  • @marcelmircus8087
    @marcelmircus8087 2 года назад +3

    Awesome video and very interesting. Also, you make it really easy to understand it's just perfect. Thanks and keep it up!

  • @ormarion552
    @ormarion552 2 года назад +3

    Might be good to precise amyl nitrite also act as a vasodilatator, this conter the vein contraction effect that cyanide produce when ingested. I personally have been pretty badly cyanide poisoned once while doing chemistry. I can relate to the asphyxiation effect, and more especially to the muscles spasms. I suffered of uncontrolled spasms in arms and neck for the next 4 to 5 month, but it seem like it ended up wearing off

  • @gangadharr3524
    @gangadharr3524 Год назад +2

    It's amazing to know how chemistry and biology together works in body

  • @LFTRnow
    @LFTRnow 2 года назад +1

    Sodium Thiosulfate (known originally as Hypo) will also react with cyanide though it is normally given along with other therapies because it has poor absorption and slow onset.

  • @SimonSozzi7258
    @SimonSozzi7258 2 года назад +4

    What happens when you inhale poppers? And is the injection a different solution? I'm assuming!

  • @srremus9781
    @srremus9781 2 года назад +3

    cyanide also bonds very strong to the iron atoms in the blood hemoglobin to inhibit the transport oxygen.

  • @jr0588
    @jr0588 Год назад +2

    I too remember that the mitochondria is the powerhouse of the cell.

  • @TNTboom-ji5zi
    @TNTboom-ji5zi 2 года назад +2

    Trying an experiment! Cracked open several cherry pits and collected the seeds i wonder if it’ll have an effect

  • @pbjracing14yearsago49
    @pbjracing14yearsago49 2 года назад +3

    Do a video on thallium next! Super obscure poison, almost no unusual symptoms.

    • @darkscienceyt
      @darkscienceyt  2 года назад +4

      I never heard it before, so it really must be obscure! Thanks for the idea!

  • @nabetzeleira
    @nabetzeleira 2 года назад +4

    This looks familiar but diferent at the same time, like a wierd dejavu.

  • @loki76
    @loki76 2 года назад +2

    How can it kill so quickly? Yes there are a lot of "units" but how does it spread to every cell in the body in mere seconds or minutes to make you die?

  • @RodrigoRamirez-eq6gj
    @RodrigoRamirez-eq6gj 2 года назад +2

    Correction. The affinity of the cyanide anion for iron in hemoglobin is orders of magnitude higher than that of oxygen, effectively blocking the uptake of oxygen and the removal of CO2. Certainly some cyanide will make it inside cells and wreak havoc there, but the most important mechanism of asfixia is the blocking of hemoglobin.
    Iron-cyanide complexes are so stable that they once were used as pigments. The most popular is Prussian blue.

  • @WardenWolf
    @WardenWolf 2 года назад +3

    I previously thought it just shut down your respiratory system like so many other things do, but oh no, it's FAR worse. That's freaking evil.

  • @TheMikouu
    @TheMikouu 2 года назад +8

    As I recall from the book, poison that killed Joffrey was causing larynx swolling so severe that made breathing impossible, but video very interesting still.

  • @stevenborgens1390
    @stevenborgens1390 2 года назад +2

    You can also dilute cyanide with Cobalamin aka Vitamin B12. So, if in the situation many walmarts sell liquid B12 in the Vitamin aisle. Liquids would be your best bet in a strenuous situation, well actually gaseous is might be the quickest but inhaling acid is also probably a bad idea, just like cyanide.

  • @hushmypuppy
    @hushmypuppy 4 месяца назад

    THIS IS THE MOST UNDERRATED RUclips CHANNEL

  • @davidci
    @davidci 2 года назад +6

    While we're on this topic, how about a video on chloroform? Recently watched a video that showed misconceptions and one of them is that chloroform use in movies are very inaccurate and actually should take way longer.

    • @darkscienceyt
      @darkscienceyt  2 года назад +1

      Hey thanks for the idea! I'll run it by my patrons

  • @pandi7978
    @pandi7978 2 года назад +3

    imagine dying from getting coxblocked

  • @Mak10z
    @Mak10z 2 года назад +1

    A lot of good info in this video :) thanks!

  • @Arthurschkil
    @Arthurschkil 2 года назад +1

    Thanks for all the helpful content

  • @SirLightfire
    @SirLightfire 2 года назад +3

    I'm curious,
    Couldn't ATP be supplemented as an IV to extend the time a patient has to recover?

    • @marcos11vinicius16
      @marcos11vinicius16 2 года назад +5

      I think ATP doesnt last that long before breaking down

    • @loicdelcourte9423
      @loicdelcourte9423 2 года назад

      You would need a tremendous amount and a constant flow of it in order to keep someone alive.

    • @epistax4
      @epistax4 2 года назад

      ATP is needed where and when it's made (or tried to be made). If I recall correctly, the cells actually spend ATP to allow particular molecules to cross their cell membranes, so you might have a chicken-and-egg issue if you need to spend ATP to allow ATP to flow.

  • @gunkcancerr
    @gunkcancerr 2 года назад +3

    MITOCHONDRIA IS THE POWERHOUSE OF THE CELL YEAAA BABYYYY 💪

  • @iroshanaravishan1388
    @iroshanaravishan1388 2 года назад +2

    Thanks for sharing the knowledge....

  • @rashequddinahmed9511
    @rashequddinahmed9511 2 месяца назад +1

    I don't get it, potassium reacts violently with water, so can potassium cyanide be mixed coffee, tea, juice, milk or any drink. Or it'll react violently

  • @dasdough
    @dasdough 2 года назад +3

    I love science and your videos but I never understand the maths part of it as I have dyscalculia. Are you able to make it more simplified?

    • @darkscienceyt
      @darkscienceyt  2 года назад +2

      Hey there! The math part isn't really necessary to understand, so don't sweat it. It's just a way of showing how I arrived at the number 180 million. What's important to know is that when you take a lethal dose of cyanide (for a 175 lb adult), there's 180 million cyanide molecules for every 1 cell in your body. This explains why such a small pill (size of a tictac) is able to kill you so quickly.

    • @dasdough
      @dasdough 2 года назад

      @@darkscienceyt thank you, I appreciate your response.

  • @moistmike4150
    @moistmike4150 2 года назад +6

    You mention that the antidote to cyanide is amyl nitrite because it converts hemoglobin into magnets for cyanide molecules. Hemoglobin carries oxygen, but when hemoglobin binds with amyl nitrite, it can no longer carry oxygen to your cells. You forgot to point out why you can't convert > 30% of a body's hemoglobin using amyl nitrite. It's because once the body loses > 30% of it's hemoglobin's capacity to carry oxygen molecules, you basically don't have enough hemoglobin left in your body to carry enough oxygen to sustain life. So if your dose of cyanide is > than what you'd be able to bind with amyl nitrite to at most 30% of your total hemoglobin, you'll die anyway, no matter how much antidote you're given.

    • @Aironaught1
      @Aironaught1 2 года назад

      Surely at this point you start blood transfusions?

  • @HazardSJ
    @HazardSJ 2 года назад +1

    From personal experience, you can also feel a burning sensation as well, it's a very unpleasant and desperate feeling and you suddenly feel heavier.

  • @Lerebel301
    @Lerebel301 2 года назад +2

    It's nearly the same thing with some lacrymal gaz (like the CS Gaz : chlorobenzylidene malonitrile) who have cyanide group (CN) in their composition, isn't it ? Metabolisation of the molecule that's in CS gaz, free the cyanide, affect the metabolism of the cell, and cause incapacitation of the subject. Have I well understood how it works ?

    • @horsthorstmann2480
      @horsthorstmann2480 2 года назад

      I’m not an expert, but I think in first place CS is working by reacting with the moisture in u eyes and lungs and create HCL. U are right, that it is metabolized to cyanide, but I think that’s only relevant if u ingest a lot of it.
      Many lacrymators working by creating HCL and if cyanide poisoning would be a thing when used as an aerosol teargas, they would probably not used it for that purpose by the police or even allowing normal ppl. to own this for self defense over here in Germany.

  • @ronisugianto4416
    @ronisugianto4416 2 года назад +3

    I will take cyanide when i cant deal with my severe depression anymore. Life still really sucks.

  • @assassin4rent
    @assassin4rent 2 года назад +3

    Cyanide literally is made up of sad face emoji. That’s how you know it’s bad

  • @mdiciaccio87
    @mdiciaccio87 9 месяцев назад

    Thanks for the practical advice.

  • @Sutterjack
    @Sutterjack 2 года назад +2

    Fascinating but you didn't say how rapidly the Amyl Nitrate has to be administered to counteract the effects of cyanide poisoning.

  • @user-rp5or1ik5l
    @user-rp5or1ik5l 2 года назад +8

    If schools got topics as interesting as these, I wouldn't skip a minute of it.

    • @ghostarmor87
      @ghostarmor87 2 года назад +1

      No you will learn that there are 150 different genders and men can give birth… and you will like it.. no need to learn this useless cyanide crap

    • @woodrowwant6216
      @woodrowwant6216 2 года назад +4

      They do you just don’t pay attention

  • @paulmicheldenverco1
    @paulmicheldenverco1 2 года назад +3

    I just had a bad feeling that Cody took a larger dose than what was safe. I hope this is not the case because I haven't seen the end of the segment.

  • @zaneo3
    @zaneo3 Год назад +2

    I was in the shower and was like “huh I wonder how poison works” this is the first video that pops up and I was like “yeah how does cynide do that” thank you

  • @johns1625
    @johns1625 2 года назад +1

    I need to know exactly to the letter why it is that every person remembers Mitochondria as the powerhouse of the cell but basically none of the other organelles.