The Student Who Ate 5-Day Old Pasta And His Liver Shut Down
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- Опубликовано: 17 апр 2022
- @chubbyemu video: • A Student Ate 5 Day Ol...
Audio only version: anchor.fm/chubbyemu/episodes/...
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A Student Ate 5 Day Old Pasta For Lunch. This Is How His Liver Shut Down.
References:
Fulminant Liver Failure in Association with the Emetic Toxin of Bacillus cereus. www.nejm.org/doi/full/10.1056...
Sudden Death of a Young Adult Associated with Bacillus cereus Food Poisoning. www.ncbi.nlm.nih.gov/pmc/arti...
Acute Liver Failure after Ingestion of Fried Rice Balls: A Case Series of Bacillus cereus Food Poisonings. doi.org/10.3390/ toxins14010012
Fatal Family Outbreak of Bacillus cereus-Associated Food Poisoning. www.ncbi.nlm.nih.gov/pmc/arti...
Bacillus cereus and its food poisoning toxins. pubmed.ncbi.nlm.nih.gov/9435100/
Liver Zonation - Revisiting Old Questions With New Technologies. www.frontiersin.org/articles/...
Bacillus cereus food poisoning. www.nejm.org/doi/full/10.1056...
Tox and Hound: D and Toxin-Induced Hepatic Microvesicular Steatosis toxandhound.com/toxhound/ff-m...
ENCEPHALOPATHY AND FATTY DEGENERATION OF THE VISCERA. A DISEASE ENTITY IN CHILDHOOD. pubmed.ncbi.nlm.nih.gov/14055...
Whatever happened to Reye’s syndrome? Did it ever really exist? pubmed.ncbi.nlm.nih.gov/10470...
Regulation of the structure and activity of pyruvate carboxylase by acetyl CoA. pubmed.ncbi.nlm.nih.gov/22120...
Prevalence of Alcoholic Fatty Liver Disease Among Adults in the United States, 2001-2016.
pubmed.ncbi.nlm.nih.gov/31063...
Goldfrank's Toxicologic Emergencies 11th ed. 
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I love how even though he is a literal doctor, he still had to hold back a chuckle while saying the mitochondria is the powerhouse of the cell
Glad you pointed out that crippling student loan debt was the original factor in AJ's death.
This is the most irrelevant point in the entire presentation. Wtf are you on about?
@@IIBr0KenII I dunno. Seems pretty relevant if crushing student loan debt is causing people to resort to taking a chance on spoiled food.
@@IIBr0KenII idk if youve never been to college or something, but if youre not going to community college youre likely taking out very hefty student loans that youll spend your life paying off. probably had a factor in why he ate 5 day old pasta
@@mtheory85 hopefully you’ll keep in mind lifestyle and diet choices are something that can aid in clinical studies, or help improve the outcome of the next case. It helps paint the bigger picture of the case: college student can afford pasta, pasta left out allowing B. Cereus to grow, and ingestion of the pasta leading to buildup of Cereulide causing the liver failure. It’s not the most irrelevant, just a factor that helps figure out what happened. Treatment-wise, the info isn’t gonna show up in time.
I get what you're saying. A diet EXTREMELY high in starches is all so many young people can afford.
I remember seeing a repost of this case on a facebook ‘weird facts’ page, with a lot of the important details left out, and a huge amount of people said he deserved to die for being stupid enough to eat spoiled food. We’re living in the worst timeline.
Worse than people bringing their children to a beheading for entertainment? I really disagree.
@@adisjamak5825 how...is that at all related to what they're talking about?
@@adisjamak5825 Point in time and timeline are 2 completely different things. We still exist in the timeline where people brought their kids to beheadings for entertainment.
some people don't think at all, they are so brutal with their comments. If it would happen to their family member, they'd have a completely different tone
I'm not justifying his death but 1 L of pepto bismol when the recommended dose is a couple spoons is dangerous even if we excuse the cultured pan (he didn't clean the pan he cooked on).
This video appeared as I was taking a study break for my ANPS exam (which is in an hour) on liver function. Great breather that still engaged me with the stuff I'm learning about, thanks for the great timing!!!
Best of luck! Remember to stay hydrated prior to the exam, and keep as calm as ya can!
How did it go?
@@csp.9203 Pretty sure I aced it, thanks! :D
@@nattata9273 Nice work! I hope you continue to kick ass, Nat. Make yourself proud of yourself.
Good luck, but I am sure you did well
What I had understood from the original video is that although the cereulide might have been sufficient to cause liver failure, the addition of the salicylate overdose significantly hastened the timetable of the failure. I think the cognitive bias there is that we can all see ourselves in the situation of eating the bad pasta, but not see ourselves consuming an entire bottle of Pepto; since the latter is something we believe we can control, we optimistically attribute more blame to this latter factor and less to the former.
My thoughts exactly. We all feel a sense of loss of control knowing that something we might do or have done in the past could be our downfall. it's scary at worst, humbling at best.
@@KarmatheCorgi It's really the reminder though, isn't it? Speaking as an American, there are mass shootings nearly daily and car accident definitely daily. Being at the wrong place, time, eating the wrong thing in the place, time, anything can be your downfall at any moment. Cell phone batteries and charger malfunctions kill people and they're very regular to most people now a days.
The regularity of death should be scary and humbling, because that's your way of remembering your time is deeply limited and you shouldn't live in fear, but in reverence for your opportunity to live at all. 30,000 isn't a big number if you think of it in terms of money made in a year's time, but 30,000 days is over 82 years of life lived. Perspective shifts happen when you need them to. 20 year olds are not infallible, and it's great to teach them that without sugar coating it.
I agree. My dad's partner had stomach inflammation and she said the pain was unbearable, and the only thing keeping her from screaming in pain was pepto bismol. She told me once that she went through a whole bottle in a day.
This comment is the key to the entire lecture
Great comment. The bacteria alone can cause liver failure. People really latched onto the medicine aspect when in reality the bacteria alone, and poor food safety that leads to its growth, were enough to be deadly on its own.
I’m just a regular guy and am just smart enough to follow this. Medical students and staff must love this stuff. Another great presentation Doc. God Bless.
We do x this is my pre-work listening ;)
Hypo- meaning low
It’s far more about knowledge (memory) than intellect, unfortunately. If it primarily relied on being “smart”, as in approaching or exceeding genius, the result would be a significant shortage of medical doctors.
@@anhedonianepiphany5588 maybe I should have been a doctor. IQ around 135. Oh yeah, that’s right, I’m poor. Lol.
@@anhedonianepiphany5588 while very true, I find it unfortunate that the highly logical, methodical problem solving strategies aren't more elevated in the medical professions. Perhaps it is instead because of what you pointed out, but it is always frustrating to encounter a doctor who does not "empty their cup" before engaging in medicine (which I find all too often)
You know I went to school for IT network administrator . I don't understand half the words that are said, but it's so well spoken and so thought through, that I watch for the way the information is delivered. I always know more after than I started off with. Love the main channel, but enjoy the second just as much. Be well doctor.
That little smirk at 6:25 is all I need to tell that you enjoy writing these so much. You inspire me, Dr. Bernard.
Exceptionally detailed, yet expertly organized, clearly explained, engagingly presented. Entire setting has a good look (seated and talking hands work well). Thx, Dr Bernard!
It feels like office hours with Dr. Bernard after asking him why you failed the question on his exam. I really enjoyed it.
💖💖💖🎵☝️!!
@@jaymzx0 If I only had teachers like him at med school, my mental health and self confidence would have done better !
An instant click. What a treat. Thank you!
agreeddd
as a long time chubbyemu enjoyer, it’s a real treat to have this second channel to enjoy as well. thank you dr bernard!
People raged because they thought you besmirched the good name of pasta? I can imagine these people walking up to you in the street, slapping you with a glove, yelling "I demand satisfaction, sir! Pistols... 10 paces at dawn!”
No but seriously, how could they miss the cereulide part. Unfortunately I think this reflects a lot of people's thinking generally though, on a lot of topics. People prefer binary thinking ....yes or no .....black or white .... it's easier and you have to think less when you pretend everything's not complicated.
I went to school for broadcasting and I can barely remember basic first aid, but I'm grateful for Chubbyemu Medical School!
Straight up this content is so easy to follow and actually really compelling. Always the perfect length too!
I really appreciate how you break down the thought process of both deducing what is going on, as well as the thought process in how you explain the information to the public. Thank you for taking the time to make this video and share it.
I am absolutely loving your videos. I am a Paramedic and love studying medicine. I love how you go more in depth on this channel. Keep up the good work. I hope to learn much more from you.
I LOVE these videos! I'm not a medical professional, and only understand abt 60% but these really make me work my brain. These are what RUclips is made for. Thank you! More please...
The break down on how you make videos consumable by the general population is invaluable for anyone trying to communicate highly technical concepts to others without the base knowledge.
As a side note, I think it may help to stress that if the body is expelling good do to food poisoning, medications should not be used without the guidance of a medical professional that understands how dangerous the interactions can be. My Grandfather was a DO and he always said to never suppress vomiting until you know the cause. Never block a fever unless it is dangerously high etc. Always go to the hospital for vomiting that lasts more than a day. For good reason.
Who needs medical school? I've learned everything I know from Wikipedia, Googling the strange words on my medication notices, Dr House and Chubbyemu. Where do I sign up for a degree?
I am consistently amazed at your talent as an educational speaker.
I have never had any formal medical education however I am endlessly interested and have always done what research I could on my own; and yet you manage to never lose me due to the care you put into explaining any technical term.
Great video! Listening to you present your process and reasoning is enlightening. I'm thankful to have another supplementary video! Thanks!
love this setup dr!! i feel like I’m getting lectured and your diagrams and explanations are super thorough
I live in the midwest. Specifically somewhere between California and Texas, or in any of the four states along that region. There was a house in my family that was built by my grandfather. He bought some land in a tiny little lake-bordering village then hauled a house frame he found abandoned to the land. Though it is in a town it is still technically quite remote. The town is longer than it is wide and so the tourist section is far from the residential section. This is important because the 'residential' section sees very few actual residents. Either you are like my family and have a vacation home there and only visit despite being a part of the community, or you're quite elderly and retired there. Either way the residential side of this tiny town sees far less human activity, and so wild life is as much a part of the land as the houses built there.
Deer and mountain lions will manifest in your yard. I even once had a bear wander onto my property to eat a watermelon I left out for the deer. More importantly, a lot of hostile insects like to share your home with you. The spiders are fine, they've been coexisting with humans for thousands of years and know well enough to hide in the shadows where they can benefit from our shelter while eating our pests without the danger of us killing them. But scorpions? Different story.
My middle uncle on my mother's side used this house most often. Either he was using grandpa's old house as a home during hunting season, his favored hobby. Or he was staying there while working a friend's ranch in the summer months. Either way he would often spend months there with no visitors, only the people he might speak too at the local church on Sunday. The nearest neighbors have houses in eyesight but that's barely a comfort when they're elderly or only visiting during summer to swim in the lake.
It so happens my uncle isn't a particularly... clean man. He's every man in how he keeps a house. Responsible enough to clean before leaving but slobby enough to leave clothes out and about on the floor. Like I just said the wildlife isn't afraid of human homes in this quiet little village. Since my grandpa built this house from nothing but a frame insects can very easily get in. Normally they don't when a human is in the home, but scorpions aren't particularly bright and will come in regardless of danger. You find them once in a while under a carpet or in a corner dead. My uncle got unlucky and found a living one in a shirt he left on the ground. He never saw it, only felt it sting him... a lot. He lost count of the stings he received before he could throw the shirt off.
In seconds his vision went black. It sticks with me that his first instinct was to struggle through the house to the door so he could sit outside. My uncle knew if he died in the house it could be days or weeks before he was found, and then only because of the smell of his corpse rotting into the floor. He didn't want that, so he found his way to a bench outside the house hoping someone would see his corpse before he could rot. He didn't die. By some fucking miracle he survived a large number of stings from a particularly terrified scorpion.
I love how your explanation encompasses every level, from the sociopolitical to the atomic.
Thank you for your intelligence and motivation
I can’t imagine how many times you reviewed this for the sake of thoroughness and accuracy, though it certainly paid off.
I like this. Informative. And useful as a refresher for the knowledge the medical professionals sometimes forget.
I really enjoyed how you explained the concept of interwoven factors and not just assuming that one factor is responsible- food for thought!
Thanks for the detailed overview Dr. Bernard!
I’ve been watching your chubbyemu videos for around 2 years now and it’s a shame that I only discovered this channel today! As an ap biology student I surprisingly understand quite a lot and those things that I’ve only briefly heard of sofar are explained amazingly, thanks a lot for spreading knowledge, it’s just awesome!
Aweome video. I really love these more in-depth looks at the cases. This was particularly good with the parts discussing the reception of the video, and the more in-depth background on the many possible questionmarks when a patient like this arrives! Great job!
Studying much of this in med lab tech school atm and it's really cool to synthesize my micro, hematology, histology, etc... courses together in this way. kept thinking of the b. cereus i cultured last week, the common clinical presentations, my liver slides in histo and much more. thank you Dr.!
Amazing work Dr Bernard!
Lovely, I'm a med student and your in depth videos are great for brushing up on my knowledge.
Thank you Bernard, good stuff as always. Very entertaining as well
Fascinating, informative, and well thought out video as usual. Thank you Dr. Bernard!
these graphics are so well done
Thanks for the more in-depth review of this case. I think it makes more sense to me now!
Man this channel is Gold and so is your other channel! Thank you a ton ! And hope all is well ! 🙏
I wish I had these videos when I was in nursing school. They are so clear and break medical terms and processes down into a way that is so clear.
if any of you college student are ever looking to choose a carb of choice thats cheap, easy to prepare, store and reheat, your best bet would be potatoes or rice. These 2 complex carbs can be frozen and reheated quick, while pasta will lose its texture usually after being reheated and it cant be frozen or else it would turn to mush.
i want to thank you for your videos. my son is 10 & he loves watching your other channel he just started watching this channel & he is hooked. i appreciate that you explain things in a way that is not only interesting but informative he’s learning things that normally he never would any other way. so i wanted to say thank you for you videos.
Dr. Bernard, I'd like to thank you for your through presentation, it is always a joy to behold.
I love to watch both the simplified version for general public and this review with straight-forward vocabulary for us med students.
This video is still simplified, more for MS1. Not nearly at the level of residents or MS3s
The info in this is fantastic! So good.
Thanks for making things easy to understand!!! You mentioned that the pasta sat out all day? So the issue wasn't necessarily the age of the pasta but improper holding?
THANK YOU. Please keep doing these.
To expand on that - this is the first video I have seen of you just talking as yourself, and I enjoyed it. Not all of us are going to follow every detail, but we have google.
Thanks for this! I am learning how to create soci(et)al impact with my research, and the way you explained your process really helped.
I love you for this intro on college debt
as a biochemist, i really liked the video and understood everything. thanks for the in depth info!
Excellent review.
he is gonna get barf of those hoodie strings which is unacceptable
I'm glad I wasn't the only one thinking that
I love this new approach to your videos, its really engaging.
I have a path/histo exam on the liver this week! This was a great video and good review!
its really cool to get a breakdown of the reasoning of the process
This video was awesome. Thanks.
Interesting to see the heme review of this story from the main channel. Like the format and the use of the original video. Great job as always, thanks for sharing!
Thank you, Doctor, for educating us. Real life is indeed complicated.
Great explanation, I can follow this on the surface level with very little prior knowledge. Yet the information was throughout enough that there were no “black boxes” - I’m somewhat confident that I can identify at least the most major aspects that I didn’t properly understand, and study them myself.
Love heme review thanks Mr Emu
Awesome, love these more in-depth vids!
ChubbyEmu is the reason I threw out 4 cream cheese packages yesterday. They'd been out for 8 hours. While thinking I could still use them, I started hearing chubbyemu background music and said, "NOPE!" 🚮
LS is a __ year old woman *presenting to the emergency room* ☝️
Unopened would likely have been fine because of the acidity and sanitized setting of the original packaging. But better safe than sorry if you aren't familiar with the details.
They almost certainly would have been fine. Certainly no risk of bacillus cereus anyway, as it is only present in grains.
Awesome mix of information, explanation and education, from someone who obviously researches every aspect of the medical dilemma, and consults reliable experts. Dr Bernard has everything that makes a world class educator. And this channel has 2 to 3 times the information of the related chubbyemu videos.
I wish All doctors were as knowledgeable and caring as you!!
Too many these days are just looking for the $$$$
We just covered these metabolic pathways in biochem and I found this video fascinating. It’s really cool to see how relevant understanding metabolism is to human health
Haven't seen a single podcast update since August last year. I thought it was down to Dr Bernard being so busy.
Half an hour after posting this the podcasts have started to pop up anew. This is great stuff.
Me: *feels clever for watching chubby emu*
Heme review: it took me over a week just to dumb it down enough for you to understand it
As an academic, I loved the first part-- shots fired at the student loan-crippling debt industry. (no sarcasm). The science was good too. 😘 Keep it up!
while I understand the reason to simplify the content for a general audience on main channel, this level of detail is much more comfy. it makes more sense. & helps put together bigger pictures of body function. I feel like this level of detail should be main content. That is just me tho. i don't want to direct what your course is or what you do.
It is sooooo cool that u still take the time to make the indepth content ! Shows that u didn't sell out.
Much appreciated & respected.
Thnx for all u do
This was super informative as someone who's interested but not in the field.
The human body is amazing in its ability to do whatever it takes to survive. What an educational video!
Omg I was obsessed with Cubby emo because I love learning I can tell I’m gonna love these videos I get high on knowledge thanks for fueling my brain and teaching me something I love it 😻
0:30 - damn well said treatise on upward mobility and crippling student loan debt, you just get it
5:25 I think my record for the longest a box of pasta has lasted me is about 11 days. My fridge does get pretty cold, but that is a long time. The pasta was exactly the same, as far as I could tell, as it was on day 1, and I didn't experience any problems with it. It was 2700 calories and I was withdrawing 238 calories per day.
I love your videos on your main channel and think I'm going to love this one even more. These days I'm a rabbi but my first degree was in Biochemistry and Chemistry, so the little extra depth makes them even more fun. Not sure fun is the right word.
There is never just one problem. It has to be a combination. Otherwise I would wonder how am I alive in my 33.
the case of this guy sounds like an avoidable meme scenario a dumb kid eating trashy food causing food poisoning but when you look at the case indepth its extremely rare and he got the absolute worst of it
@@Ninja1Ninja2 Well, in our cuisine there are foods you cook and let the "do their job" in dark cold place (fridge is too cold) for 3 days before reheating it and eating.
Some foods are expected to be eaten that day, but are also recommended to be eaten after one or two days after if you have hangover.
And especially with soups, few kinds of cake-like foods and spreads it is expected those will last few days, so you keep them in a fridge and you have about a week to eat it (no preservatives used).
This is an exceptional video. Thank you for your great work.
thank god a longer form channel. I can't deal with the tiktokification of knowledge
A very interesting video. I look forward to all your new videos plus sometimes watching old ones.
I got the idea from the original video that it wasn't just the cereulide poisoning, that the addition of the bismuth subsalicylate made the liver failure far worse. But it's good to recognise that the addition may not have helped.
A 5 day old pasta ate liver and his student broke down.
...or a 5 day old student broke down after eating his liver with pasta.
Bjarne Stroustrup. That's awesome you took a shot of the C++ book.
Hi, would you like to make an episode on Reye's syndrome? I guess it fits this channel's regural content, plus there are still guys who happen (sometimes due to lack of education and ignorance, sometimes as a reslut of doctor/pharmacist mistake) to give aspirin to their children.
He mentioned it in the essential oils video I think. Toddler basically drank pure liquid aspirin. I’d have to go back and watch it to see how in depth he went.
I love to watch these videos... leaving a comment here to remember to watch this
That video you uploaded long ago made me never eat food past a day or two. Thank you for a new fear but it's better to be safe
So this is nothing to do with the video persay, but I love the boom arm you have there for your mic. Where did you get it?
I like this format
Lol I love the way you describe college in the beginning. So true!
Dr. Bernard droppin' knowledge.
Wow that sentence about student-loans is so beautiful!
I've always thought of your videos as click baby and water down for the public, buzz what I'm seeing here is I really get to see your depth of knowledge and your skill at researching, and it's not only that, but you're very good at presenting it in a way that is both complex enough to be interesting but also easily accessible by beginner's. You're very good at this.
Honestly. It's a wonder I survived undergrad. My diet was fucked. Eating peanuts and peanut butter for dinner for a semester, heating rice in the microwave, taking caffeine pills every day for studying sometimes on an empty stomach, eating ramen everyday... Dodged a bullet bruh.
You can keep food safe for considerably longer than two or three days, regardless of the type of food, as long as you have an understanding of food safety. I regularly do this myself, cooking a weeks worth of food at a time. I'm not home often, and eating all my meals at restaurants is expensive and unhealthy. But I would stress that it's a process that has to be followed, or you very well could get sick.
Bless us with some knowledge
Just put it in the freezer. It will stay good for weeks if you keep it frozen.
@@alexstromberg7696 what do i do when i wanna eat it?
@@sergiootero5904 you microwave it?
@@alexstromberg7696 Some cooked foods can't be successfully frozen in the home, though.
This probably going to sound like a stupid question, but does the quantity of the spoiled food consumed play a huge role in this? Say the guy ate a bite or two and decided that something wasn't right and tossed the rest. Would that have been toxic enough to send him to the hospital or kill him? How about if it was just in his mouth and he spat it out?
I would love if Dr Bernard answered this
It certainly does! I'm a radiopharmacist (so Emergency medicine isn't my specialty) but based on the available literature, eating more of the spoiled food is riskier.
This is because with each additional bite, you are increasing your chances of ingesting harmful bacteria. The best analogy would be pregnancy: having more sex increases your chance of getting pregnant. However, even if you only have sex once, you can still end up pregnant.
Eating one bite could end up with you getting sick. Eating a larger quantity increases those chances even further.
Sorry this is sorta long lol
@@ylvavarynkottir2265 a great answer!
I think so too. It’s like the amount of bacteria your immunity would have to fight and win. Even a spoonful which you spit out has a potential to ingest billions of that virus/ bacteria and at what concentration. Also that should be the kind of virus/ bacteria that your body can fight and win. If it’s metal poisoning or some meds overdose, definitely weight matters. I’m also thinking about snake venom, amount matters. If your question was specifically about cereulide, I don’t know.
@@ylvavarynkottir2265 thank you!
I love your videos! Without a medical background oftentimes I don't understand half of what's going on. Here's a quick summary of what I've learned from whatching your videos so far:
don't consume anything that smells funny, don't consume too much of anything (water, candy, vitamins, spice...), the dosage makes the poison - don't use more than the reccomended dose of medicine. Don't eat or drink non food items. Ethanol prevents the breakdown of methanol so it can be excreted without being broken down. Brown urin is really bad and an emergency. ALLWAYS tell doctors the truth and everything that could possibly be usefull. Alcohol is a depressant, meaning that the brain needs to send stronger signals to get a message across. Water will flow towards salt and sugar. Words with -ase mean enzymes. Stresshormones relase sugar from the cells into the blood. Hyper = high, hypo = low, emia = presence in blood. Just a few things I could think of right now :D
👏👏
Said it before, I’ll say it again. I wish I could pay Dr. Bernard to follow me everywhere in life. My anxiety would disappear.
I learned today that you should buy your child chicken nuggets from Mc Donalds if they're hungry and don't want vegetables. 😂
One thing I love about this channel is that the comments are way better lol
Dr. Bernard: "This is what you learned multiple times in school." Me: "Huh?"
Just out of curiosity; define “shutdown?” Is liver shutdown the same as liver failure, or are there specific differences? Thanks in advance!
Why didnt the stomach acid neutralise the bacteria? Why did the immune system kick in and prevent multiplication of bacterium and subsequent poisoning?
Thank you
I stg I have a biochem midterm in half an hour on these exact mechanisms lmao perfect timing
Lower fridge temperature (turn dial to higher number) to make food last longer before spoil, lower temperature preserves for longer, hence why we freeze food, don't want frozen? refrigerate