Work with a running addict. Ran every marathon he could... had a heart attack with 75% blockage in all four main arteries. You can't eat cookies and ice cream every night after dinner no matter how lean and healthy you think you are.
@@jimgillert20 his father also had a heart attack in his 40's, and he previously smoked, I don't think there's compelling evidence that a runner/athlete who enjoys refined carbs if isocaloric and not insulin resistant or showing signs of metabolic disease is at increased risk of heart disease. I would like to see this evidence if you have any thoughts genuinely interested:)
well that makes sense too me, I've had three heart attacks over the years , and my blood sugar was high I stopped eating sugar corn potatoes rice its down from 11 to 5.4 .
@@billdublewhopper3064 It depends, i had cgm. i eat single food at a time to see what spikes my blood sugar. Avocado 87, meat only until 89-90. one apple 200, 2 small sizes bread 200+. one small chocolate 200+. The rise of glucose with avocado and meat (any type) is slow. But the rest shots rocket high like really fast in a short time.
I think cancer maybe caused by insulin resistance too. When everyone talks about causes of cancer they mention that the cancer cells are mutated cells/dna that can absorb 10x more sugar than a normal cell. What if cancer cells are created on purpose to lower blood sugar as a last ditch measure as when most of the cells are insulin resistant. It means they don't take in glucose, causing blood sugars to stay high. So the body generates cancer cells to absorb all the excess sugars/glucose otherwise the blood sugar would go too high and either kill us or the organ. The reason the cancer cells replicate uncontrollably maybe simply so they can quickly absorb more sugar to reduce the blood sugar levels. Cancer might simply be a defensive mechanism against high blood sugar when insulin insulance gets really bad. This may also explain how it spreads, spreading to other areas in the body with highly insulin restant cells that don't take sugar in. It seems commence sence to me. Its funny how there are hardly any studies on insulin resistance and cancer. Im betting once you rresolve the metabolic issues/insulin restance, cancer will dissapear.
I've seen a lot of anecdotal evidence of people saying they put their cancer in to remission using a very low/zero carb diet so this wouldn't surprise me.
This was known quite a while ago. There's a special coating in your blood vessels glycocaylx or something I don't remember the name. its what helps keep cholesterol and fat from sticking to your vessel walls and when you eat and spike your blood sugar it damages it and stuff starts sticking. Its also why heart disease and diabetes go hand in hand. Its usually not a matter of if, its when you'll get it.
Bottom line fast from anything that turns into glucose and follow a lifestyle that advances metabolic health. Resolve insulin resistance or try to get rid of or manage diabetes. Keep your ticker from being insulin resistant by doing the above.
I don't think that's necessarily the case. People have reversed insulin resistance on plant based diets too. The main thing is to lose fat by whatever means necessary
Not being fat is an excellent first step. However the 'don't be fat' message has been censored as 'fat-shaming' and may lead to blaming sick fat people for their own situation?! I don't think plant-based is the way to optimum health, but it can be tool to lose weight if one has a problem. I prefer animal-based diet myself, but I have already lost the weight and am now considering what is the best way to get superior muscle mass and lower body fat.💪💪💪
@@peterpan408 yeah I certainly don't agree with fat shaming/blaming. My view is that until someone has reached a healthy weight, the optimal diet is whatever helps them get there and maintain it! Be it balanced, plant or animal based. Love to hear that you've made great strides! Good luck with the muscle building 😎
@@dangallagher6176 The problem with plant based diets is that they can't heal the physical damage to the body. Plants can help you detox - but they cannot build your body back up. Muscle mass is very important to all aspects of health and it's effortless to build muscle eating a diet rich in animal products. It's very difficult to do using plants.
I like the way you put and demonstrate studies. I do not know why 90% of cardiologists ignore fasting insulin test, and focus moe on lipid panel. I did over 10 lipid test in one year, and my TG/HDL ratio is fine. Next time I will check my fasting insulin for the first time.
Glad to know about another infrared light company. Joovv really got on my bad side. I’ve had 2 of their units. I had to send the first one in for repairs within the first year, and the second one lasted a little less than 4 years and the way they handled it was really bad. Maybe the other companies are just as bad, but that seems ridiculous for units that cost as much as they do when regular lamps last decades.
There is a difference between insulin spikes and insulin resistance. Glucose consumption can cause insulin spikes, while fructose consumption causes insulin resistance
It makes intuitive sense, heart is a muscle after all, but great to see an actual study. I wonder how insulin resistance affects the function of muscles around and in organs, such as blood vessels, the stomach and the gut
There is a risk that this isn't actually the mechanics at work. It could just be that those with metabolic syndrome/diabetes just eat more poorly, high carb diets, and that it's all just caused by oxidative stress and glycation from a bad diet.
Yes, you are correct about the carb. diet being the culprit. Cut out the carbs. and you will not be hyper insulinemic. Eat meat and animal fats. It's called carnivore.
Are you saying that independently of insulin resistance and metabolic disease. If someone ate high carbs they are at risk of heart disease? Even if isocaloric/not gaining weight ? Interested to hear your thoughts and any evidence:)
@@conradcreate In a word: yes. You can still have oxidative stress and plaque buildup even if you're not insulin resistant, don't have metabolic disease, and aren't overweight. Though you're definitely on the way to insulin resistance and metabolic disease if your diet is such, even if you're not overweight. Thin type 2 diabetics are a thing. Heck, sugar isn't even the worst for this, seed oil is.. You could get this from eating processed food, it is the food industry's favorite ingredient, or especially from deep fried food. Fries anyone? Sugar is also quite bad though, but heck if you're a starving artist and you subside on ramen, beware that instant noodles spike bloodsugar more than table sugar. White bread is high up there too.
My understanding is that muscle cells do not need to use the insulin dependent GLUT4 receptor to absorb glucose. Muscle activation draws in glucose without insulin being required. I assume this bypass mechanism applies to the heart muscle? Why would insulin resistance prevent a heart muscle from absorbing through the alternative path?
I think the connection is the other way around. Arteriosklerose is the cause of the cardio problems. You need a high level of magnesium, potassium, d3 and K2 to take calcium out of the arteries into bones. Clean, flexible arteries can bring oxygen and nutrition to all cells including the heart. If the heart muscle isn't nutrition properly...well, its pretty obvious
Maybe when insulin increases but glucose still high, it signals the liver. Also I heard high insulin drives salt retention which drives high blood pressure which can cause stress to epithelial allowing abnormal interactions with LDL.
Another great video. Literally saving lives. More than most. More than the vast majority. Kills me that basic research is so far ahead of clinical practice. Kinda outrageous actually
I’m 61, I started lifting weights 5 months ago. My blood pressure was in the 140s+, it’s now typically 116/70. I have sleep apnea, and usually a wreck napping without the CPAP, but instead a nap is now restful. Weight lifting appears to solve a lot of problems, plus I like the increased muscle in the mirror 😊
What about something like TMG...also vitamin D and vitamin k you pull the calcium out of the blood stream...also all the things people should be doing daily
Hyperinsulinemia is a marker for increased dietary glucose load, and also cortisol-driven insulin resistance. As with the brain, the oxygen-delivery prioritised myocardium prefers lactate, ketones, fatty acids (long for heart, short for brain) and other substrates over glucose. I expect the hyperglycaemic hearts had no room in their cytoplasm for more glucose so little was seen to flow in. In a heart less bathed in hyperglycemic blood there could be more dips in other energy substrates and more of a positive concentration gradient to flow glucose into those cells. Those with hyperglycaemia usually also have hyperTriGlyceridemia, and insulin resistant adipocytes dump free fatty acids and glycerol into the circulation. The heart can take all the long FAs it wants and the liver joins surplus glycerine molecules into surplus glucose molecules.
This is such an excellent piece of the puzzle! Thanks for bringing it to your audience exclamation point thinking this through I discovered that just as Alzheimer's is now called type 3 diabetes, wouldn't it make sense to call heart disease type 4 diabetes I don't have any RUclips presents. But I would love to give you this phrase and you can run with it. Maybe it will go viral I think it should.
I will add that this works because as you pointed out call insulin resistant can't take center stage instead of the LDL hypothesis. This is revolutionary
Try it, however for myself in doing carnivore I observed that I maintain blood glucose in the 90s when being active and near 70s when sitting still. When I'm sleeping blood glucose can go very low, sometimes in the 40s
Eliminating carbs is more difficult than it seems.. They hide in several animal-based foods as sugars. I don't think we need worry about getting zero carbs, since it is practically impossible.
Depends on whether you exercise or not. Cool sculpting /lipo can only remove subcutaneous fat (fat just under the surface) and it can't remove the visceral fat which is the dangerous fat surrounding your organs. If you remove sub-Q fat you won't decrease insulin resistance caused by visceral fat. If you exercise you can lose visceral fat. Lipo won't do it.
Maybe I didn't get the study, but the results are negligible. A difference from top to bottom in blood glucose of only 2 mg? A difference in systolic blood pressure of only 1.2? CRP of only .01? Those are hardly significant differences. Insulin is the only one with any significant differences, and that just confirms that there is a difference in metabolic health, and the diabetes score confirms that. So the study just confirms that metabolic health is the cause of FDG uptake differences?
When insulin resistance is prediabete, wouldn't hyperinsulinimia that's the flipside to insulin resistance, also causes metabolic dysfunction of the heart?
Yes but of course that just makes it worse in long term. Tissues get insulin resistant because they were overdosed and damaged by sugars in past. More insulin can get sugars in tissue but than are other sources disabled(ketones). Imagine that you see a drunkard laying on the ground unable to drink anymore. And your solution to this situation is to take funnel (insulin) and pour even more whiskey into his body. Our body don't allow creation of ketones when is insulin in bloodstream. It's safety mechanism otherwise could ketoacidosis happen which is dangerous.(which is type one diabetes problem, these patients don't have any insulin) But if you eat carbs and you have some insulin resistant tissues they will starve themself into failure rather than take another sugar.
Injecting insulin is what a type 2 diabetic does in an attempt to lower blood glucose. Injecting insulin raises your insulin level there by increasing hyper insulinemia. This is why the current strategy of injecting insulin in type 2 diabetics does not fix the problem and it worsens the problem. Hyper insulinemia is fixed by eliminating carbohydrates from the diet and eating a meat and fat diet which is called Carnivore. I am a carnivore success story.
That's a new info to me: a heart can intake glucose. But, considering that a heart is muscle and muscles intake glucose and lower blood glucose level, it is not a surprising finding. Unhealthy muscles do not intake glucose. Exercise is the only way to make our muscles healthy and functional. "Insulin resistance" is not an appropriate wording. "Muscle dysfunction" is a better choice.
Except hearth is always exercising. Unhealthy muscles are just poisoned. You know that saying "the dose makes poison". Problem is that we as humans were able to make scarcity source (carbohydrates/sugar - thats why we from child age love sweet taste, because is coded in our brain and our genome as scarce source) that is in nature awailable only in short time and only in one season(mostly before winter comes or after raining season) awailable always in infinite amounts and we even created condensed versions of it. In a liter of coke is close to 110 grams of sugar which is close to seven medium sized apples. Can you imagine that you would go to Macdonald and to burger and fries you would get almost two and half pound of apples to eat? But we drink it like nothing. I don't remember that I would ever eat more than three apples through day but I had no problem to drink three liters of coke after I came from work. (21 apples) and of course I was eating too. I ended up with fatty liver disease because now I now that half of that carbs in coke is Fructose and only liver can neutralize it which ends up like fatty liver disease.
so instead of people bypassing the system and trying to go keto or carnivore by not "eating" carbs, people should better find out what is blocking their cells from properly using glucose as fuel...and then they ll find out that they dont need to go keto or carnivore.
One thing that could be "blocking" their cells is just a naturally lower insulin levels, I think that's behind the "hereditary type 2 diabetes". These people tend to be thinner too after all.
I appreciate your conclusion - don't eat processed foods - but "A new study finds Insulin fosters heart plaque build up" makes no sense.You mean insulin resistance - insulin is necessary to push nutrients like glucose into the cells. By the way, there are others who have scientific evidence that fat from all sources gums up the cellular membranes leading to insulin resistance. Look for experts in the whole food plant world like Dr. John McDougall, Dr. Esselstyn, Dr. Peter Rogers.
Dietary saturated fat consumption like those from animal products cause insulin resistance. The fat binds with enzymes in the muscle cells clogging them up leaving glucose unable to be deposited into the muscles. This causes blood glucose to stay elevated because it can't be properly stored in the muscle.
So the opposite conclusion of the high fat low carb crowd. Your analysis is apparently the conventional wisdom. Thanks for bringing it to my attention. I became health conscious during the Paleo fad of the early 2000's. So I've mostly studied the positive effects of low carb eating. Not saying that the hypothesis that saturated fat consumption causes insulin resistance is correct. My question has to be about triglycerides. If high triglycerides are indicative of high blood sugar and all inflammatory markers go up when triglycerides are high then how is saturated fat responsible for high blood sugar and the deleterious effects of that?
@@puggirl415 just what I said previously. Dietary saturated fat increases insulin resistance. We have known for decades that intramuscular fat increases insulin resistance.
@@billdublewhopper3064 You just lost credibility. I asked a specific question about triglycerides blood sugar and how saturated fat could be responsible for the inflammation that comes from high triglycerides. If you don't know the answer that's fine. I won't believe a stranger on the internet just stating shit as if it's a fact though. Prove your "facts" by answering questions or citing a recent study proving your narrative. Or don't. But no one, including me, will believe you on here if can't prove your assertions or answer specific questions. I don't take on second hand thoughts spouted by ignorant third parties.
@@puggirl415 triglycerides will not cause athersclerosis. A simple 2 second gge search of insulin resistance band saturated fat will explain to you what you are looking for.
Sounds like people with serious heart disease should be taking exogenous ketones until they can change their diet and correct the issues. Won't hurt the brain either...
Theres no doubt that diabetes and coronary heart disease go hand in hand. Being diabetic is a risk factor to developing atherosclerosis. However, you cannot deny that there are still non diabetics who develop coronary artery disease. People with normal Hba1c, non diabetics, can still develop atherosclerosis.
Most type 2's don't know they have diabetes because they don't get fasting insulin tested or don't do an OGTT with insulin. If they did I can assure you that the vast majority of people with cardiovascular disease wouldn't be in a good metabolic health.
They have pre diabetes. Or fatty liver disease. Fatty liver dissease is from high amounts of fructose. Fructose is neutralized in liver but this proces is creating uric acid which is heightening blood pressure. High blood presure is weakening coronary vessels. Such vessels are than prone to develop atherosclerosis which can end up in plaque development especially if are oxidized fatty acids present. First option (pre diabetes) ends up similar. High amounts of insulin are secreted by pankreas to cram sugar into insulin resistant tissues to keep sugar levels in bloodstream close to normal . But high Insulin present in bloodstream make kidneys stop filtering out redundant water and salt which ends up in high blood pressure. And from there it is the same story.
Instead of putting statins in the drinking water like doctors were proposing in the early 2000s, maybe start putting metformin in the drinking water? 💦
All have sinned (Romans 3:23 KJV). The Lord Jesus Christ died for our sins, was buried and rose again the third day (1 Corinthians 15:1-4 KJV). Jesus shed His blood for our sins (Ephesians 1:7 KJV). Getting water baptized DOESN'T save us (1 Corinthians 1:17 KJV). We are saved by grace through faith, not our works (Ephesians 2:8-9 KJV). Only Jesus saves from hell
And follow Jesus' commands because we love Him and follow His example. In the context of this video, fast like Jesus. If you're able like Jesus, for up to 40 days. We know based on todays science, fasting will lower insulin resistance and help treat metabolic syndrome in our body, including our heart. Our body is the Temple of the Holy Spirit. Let us respect and love our body like Jesus does because He is one with the Holy Spirit.
@@domega7392 that is what the Bible says. But i know you catholics don't read it or not enough to realize that the catholic Institution is mystery babylon of Revelation 17
Dr. Joseph Kraft (father of insulin assay) once said, "those with cardiovascular disease not identified with diabetes are simply undiagnosed."
Blaming cholesterol for heart disease is like blaming cars for drunk driving accidents.
Work with a running addict. Ran every marathon he could... had a heart attack with 75% blockage in all four main arteries. You can't eat cookies and ice cream every night after dinner no matter how lean and healthy you think you are.
And he probably didn't fit the population in this trial who had metabolic syndrome traits
This is the James R. Fixx syndrome. He was into doughnuts and fast food.
@@jimgillert20 his father also had a heart attack in his 40's, and he previously smoked, I don't think there's compelling evidence that a runner/athlete who enjoys refined carbs if isocaloric and not insulin resistant or showing signs of metabolic disease is at increased risk of heart disease. I would like to see this evidence if you have any thoughts genuinely interested:)
My cousin did an autopsy on a marathon runner and told me the same.
@@DataGeek903 oh your cousin well now I'm sold ignore my request for any evidence
well that makes sense too me, I've had three heart attacks over the years , and my blood sugar was high I stopped eating sugar corn potatoes rice its down from 11 to 5.4 .
congrats
It's no the carbohydrates. I is the fatyoue eaten with the carbohydrate
@@billdublewhopper3064
It depends, i had cgm. i eat single food at a time to see what spikes my blood sugar. Avocado 87, meat only until 89-90. one apple 200, 2 small sizes bread 200+. one small chocolate 200+. The rise of glucose with avocado and meat (any type) is slow. But the rest shots rocket high like really fast in a short time.
I think cancer maybe caused by insulin resistance too. When everyone talks about causes of cancer they mention that the cancer cells are mutated cells/dna that can absorb 10x more sugar than a normal cell. What if cancer cells are created on purpose to lower blood sugar as a last ditch measure as when most of the cells are insulin resistant. It means they don't take in glucose, causing blood sugars to stay high. So the body generates cancer cells to absorb all the excess sugars/glucose otherwise the blood sugar would go too high and either kill us or the organ. The reason the cancer cells replicate uncontrollably maybe simply so they can quickly absorb more sugar to reduce the blood sugar levels. Cancer might simply be a defensive mechanism against high blood sugar when insulin insulance gets really bad. This may also explain how it spreads, spreading to other areas in the body with highly insulin restant cells that don't take sugar in. It seems commence sence to me. Its funny how there are hardly any studies on insulin resistance and cancer. Im betting once you rresolve the metabolic issues/insulin restance, cancer will dissapear.
I've seen a lot of anecdotal evidence of people saying they put their cancer in to remission using a very low/zero carb diet so this wouldn't surprise me.
Not exactly. Read up on the Warburg effect.
Thomas Seyfried explains how poor insulin function results in many cancers.
There are studies.
It’s fascinating stuff.
Definitely something to think about
It should certainly be studied but I think cancer is more complex than that. The absolute truth is that it's a DNA mutation
Thank you for talking swiftly. Makes it easier.
This was known quite a while ago. There's a special coating in your blood vessels glycocaylx or something I don't remember the name. its what helps keep cholesterol and fat from sticking to your vessel walls and when you eat and spike your blood sugar it damages it and stuff starts sticking.
Its also why heart disease and diabetes go hand in hand. Its usually not a matter of if, its when you'll get it.
This is the 3rd high quality video ive seen from you in like a week. Subbed ❤
Thanks for sharing, Mike!
Thanks!
Bottom line fast from anything that turns into glucose and follow a lifestyle that advances metabolic health. Resolve insulin resistance or try to get rid of or manage diabetes. Keep your ticker from being insulin resistant by doing the above.
I don't think that's necessarily the case. People have reversed insulin resistance on plant based diets too. The main thing is to lose fat by whatever means necessary
Not being fat is an excellent first step.
However the 'don't be fat' message has been censored as 'fat-shaming' and may lead to blaming sick fat people for their own situation?!
I don't think plant-based is the way to optimum health, but it can be tool to lose weight if one has a problem.
I prefer animal-based diet myself, but I have already lost the weight and am now considering what is the best way to get superior muscle mass and lower body fat.💪💪💪
@@peterpan408 yeah I certainly don't agree with fat shaming/blaming. My view is that until someone has reached a healthy weight, the optimal diet is whatever helps them get there and maintain it! Be it balanced, plant or animal based.
Love to hear that you've made great strides! Good luck with the muscle building 😎
@@dangallagher6176 The problem with plant based diets is that they can't heal the physical damage to the body. Plants can help you detox - but they cannot build your body back up. Muscle mass is very important to all aspects of health and it's effortless to build muscle eating a diet rich in animal products. It's very difficult to do using plants.
Berberine
I like the way you put and demonstrate studies. I do not know why 90% of cardiologists ignore fasting insulin test, and focus moe on lipid panel. I did over 10 lipid test in one year, and my TG/HDL ratio is fine. Next time I will check my fasting insulin for the first time.
Glad to know about another infrared light company. Joovv really got on my bad side. I’ve had 2 of their units. I had to send the first one in for repairs within the first year, and the second one lasted a little less than 4 years and the way they handled it was really bad. Maybe the other companies are just as bad, but that seems ridiculous for units that cost as much as they do when regular lamps last decades.
There is a difference between insulin spikes and insulin resistance. Glucose consumption can cause insulin spikes, while fructose consumption causes insulin resistance
You nailed it, Mike! Excellent advice 👍🏻
Great information!
Don't change a thing with the videos, your speaking speed is fine.
Insulin resistance = Elevated Insulin
This is why the standard of medical care in the US does not have it measured …
#Science
That is not always true. You can have high insulin and sensitive insulin at the same time.
THANK YOU!
Makes perfect sense! OK. Now question: I think you said berberine shrinks arterial plaque. Does it shrink existing plaque or prevent it, or both?
And seed oils are one of the main causes of IR…but some falks continue to claim animal fat is harmful 😂
Actually, fructose is the main cause of insulin resistance
@@ClassicJukeboxBand in what context? If you mean from HFCS maybe…if you mean from fruit - no.
I mean extracted fructose. Richard Johnson proves this
Thanks for sharing this, Mike 👍🏻
can you please start linking the studies?
Excellent and thanks for sharing
It makes intuitive sense, heart is a muscle after all, but great to see an actual study. I wonder how insulin resistance affects the function of muscles around and in organs, such as blood vessels, the stomach and the gut
This makes so much sense!! Thank you for sharing
Cancer I think thrives on this as well! Sugar is a devil
There is a risk that this isn't actually the mechanics at work. It could just be that those with metabolic syndrome/diabetes just eat more poorly, high carb diets, and that it's all just caused by oxidative stress and glycation from a bad diet.
Yes, you are correct about the carb. diet being the culprit. Cut out the carbs. and you will not be hyper insulinemic. Eat meat and animal fats. It's called carnivore.
@@vermeea1 I am on carnivore already.
Would metformin help?
Are you saying that independently of insulin resistance and metabolic disease. If someone ate high carbs they are at risk of heart disease? Even if isocaloric/not gaining weight ? Interested to hear your thoughts and any evidence:)
@@conradcreate In a word: yes. You can still have oxidative stress and plaque buildup even if you're not insulin resistant, don't have metabolic disease, and aren't overweight. Though you're definitely on the way to insulin resistance and metabolic disease if your diet is such, even if you're not overweight. Thin type 2 diabetics are a thing. Heck, sugar isn't even the worst for this, seed oil is.. You could get this from eating processed food, it is the food industry's favorite ingredient, or especially from deep fried food. Fries anyone? Sugar is also quite bad though, but heck if you're a starving artist and you subside on ramen, beware that instant noodles spike bloodsugar more than table sugar. White bread is high up there too.
Oh my!
What is your opinion on the news about that healthy people shouldn’t take fish oil because it increases risk for stroke and heart problems?
My understanding is that muscle cells do not need to use the insulin dependent GLUT4 receptor to absorb glucose. Muscle activation draws in glucose without insulin being required.
I assume this bypass mechanism applies to the heart muscle?
Why would insulin resistance prevent a heart muscle from absorbing through the alternative path?
The role of insulin is very curious. The resistance to insulin uptake is bad for most cells, so when is too much, too much
Thanks Mike. And let me guess, statins don't do anything for insulin resistance right?
And what about Berberine to help with the high sugar and insulin spikes
I think the connection is the other way around. Arteriosklerose is the cause of the cardio problems. You need a high level of magnesium, potassium, d3 and K2 to take calcium out of the arteries into bones. Clean, flexible arteries can bring oxygen and nutrition to all cells including the heart. If the heart muscle isn't nutrition properly...well, its pretty obvious
To calculate your Homa-IR score, multiply your fasting insulin by your fasting glucose, then divide by 405.
It sounds like when glucose wasn't available for the heart the liver kicked it up and created more LDL like the lipid energy model hypothesis states.
Maybe when insulin increases but glucose still high, it signals the liver. Also I heard high insulin drives salt retention which drives high blood pressure which can cause stress to epithelial allowing abnormal interactions with LDL.
Another great video. Literally saving lives. More than most. More than the vast majority. Kills me that basic research is so far ahead of clinical practice. Kinda outrageous actually
How does your heart feel? I started lifting and my heart feels better over all.
I’m 61, I started lifting weights 5 months ago. My blood pressure was in the 140s+, it’s now typically 116/70. I have sleep apnea, and usually a wreck napping without the CPAP, but instead a nap is now restful. Weight lifting appears to solve a lot of problems, plus I like the increased muscle in the mirror 😊
What about something like TMG...also vitamin D and vitamin k you pull the calcium out of the blood stream...also all the things people should be doing daily
Hyperinsulinemia is a marker for increased dietary glucose load, and also cortisol-driven insulin resistance.
As with the brain, the oxygen-delivery prioritised myocardium prefers lactate, ketones, fatty acids (long for heart, short for brain) and other substrates over glucose. I expect the hyperglycaemic hearts had no room in their cytoplasm for more glucose so little was seen to flow in. In a heart less bathed in hyperglycemic blood there could be more dips in other energy substrates and more of a positive concentration gradient to flow glucose into those cells.
Those with hyperglycaemia usually also have hyperTriGlyceridemia, and insulin resistant adipocytes dump free fatty acids and glycerol into the circulation. The heart can take all the long FAs it wants and the liver joins surplus glycerine molecules into surplus glucose molecules.
This is such an excellent piece of the puzzle! Thanks for bringing it to your audience exclamation point thinking this through I discovered that just as Alzheimer's is now called type 3 diabetes, wouldn't it make sense to call heart disease type 4 diabetes I don't have any RUclips presents. But I would love to give you this phrase and you can run with it. Maybe it will go viral I think it should.
I will add that this works because as you pointed out call insulin resistant can't take center stage instead of the LDL hypothesis. This is revolutionary
A lot of people are developing this issue.
Since fewer people stopped smoking..unless they're vaping
I wonder how people who predominantly use ketones or fatty acids for energy to power the heart muscle fare? For example those on Keto or Carnivore.
Try it, however for myself in doing carnivore I observed that I maintain blood glucose in the 90s when being active and near 70s when sitting still. When I'm sleeping blood glucose can go very low, sometimes in the 40s
I'm carnivore.
CAC scan reveals zero arterial plaque in my body.
Full carnivore for 9 months and I am 57.
Eliminating carbs is more difficult than it seems..
They hide in several animal-based foods as sugars.
I don't think we need worry about getting zero carbs, since it is practically impossible.
@@peterpan408… meat has carbohydrates in it ????
My cac score was 909 at 52 at 56 it is 1245 I passed a stress test and the doctor said I did not have heart disease. past three years carnivore.
My fasting insulin is 17 and fasting sugar is 86. How could I bring my insulin down to 3?
What if we manually get rid of belly fat via cool sculpting or liposuction? Does that decrease insulin resistance, since fat cells decrease?
Depends on whether you exercise or not. Cool sculpting /lipo can only remove subcutaneous fat (fat just under the surface) and it can't remove the visceral fat which is the dangerous fat surrounding your organs. If you remove sub-Q fat you won't decrease insulin resistance caused by visceral fat. If you exercise you can lose visceral fat. Lipo won't do it.
@@puggirl415 I just learned something. I didn't realize it was only subQ fat. Thanks for that! 😊
Maybe I didn't get the study, but the results are negligible. A difference from top to bottom in blood glucose of only 2 mg? A difference in systolic blood pressure of only 1.2? CRP of only .01? Those are hardly significant differences. Insulin is the only one with any significant differences, and that just confirms that there is a difference in metabolic health, and the diabetes score confirms that. So the study just confirms that metabolic health is the cause of FDG uptake differences?
When insulin resistance is prediabete, wouldn't hyperinsulinimia that's the flipside to insulin resistance, also causes metabolic dysfunction of the heart?
Now need to understand, does injecting insulin allow heart and muscle more access to glucose then
Yes but of course that just makes it worse in long term. Tissues get insulin resistant because they were overdosed and damaged by sugars in past. More insulin can get sugars in tissue but than are other sources disabled(ketones). Imagine that you see a drunkard laying on the ground unable to drink anymore. And your solution to this situation is to take funnel (insulin) and pour even more whiskey into his body. Our body don't allow creation of ketones when is insulin in bloodstream. It's safety mechanism otherwise could ketoacidosis happen which is dangerous.(which is type one diabetes problem, these patients don't have any insulin) But if you eat carbs and you have some insulin resistant tissues they will starve themself into failure rather than take another sugar.
Injecting insulin is what a type 2 diabetic does in an attempt to lower blood glucose. Injecting insulin raises your insulin level there by increasing hyper insulinemia. This is why the current strategy of injecting insulin in type 2 diabetics does not fix the problem and it worsens the problem. Hyper insulinemia is fixed by eliminating carbohydrates from the diet and eating a meat and fat diet which is called Carnivore. I am a carnivore success story.
Define insulin resistance.
That's a new info to me: a heart can intake glucose. But, considering that a heart is muscle and muscles intake glucose and lower blood glucose level, it is not a surprising finding. Unhealthy muscles do not intake glucose. Exercise is the only way to make our muscles healthy and functional. "Insulin resistance" is not an appropriate wording. "Muscle dysfunction" is a better choice.
Hearts prefer fat
Except hearth is always exercising. Unhealthy muscles are just poisoned. You know that saying "the dose makes poison". Problem is that we as humans were able to make scarcity source (carbohydrates/sugar - thats why we from child age love sweet taste, because is coded in our brain and our genome as scarce source) that is in nature awailable only in short time and only in one season(mostly before winter comes or after raining season) awailable always in infinite amounts and we even created condensed versions of it. In a liter of coke is close to 110 grams of sugar which is close to seven medium sized apples. Can you imagine that you would go to Macdonald and to burger and fries you would get almost two and half pound of apples to eat? But we drink it like nothing. I don't remember that I would ever eat more than three apples through day but I had no problem to drink three liters of coke after I came from work. (21 apples) and of course I was eating too. I ended up with fatty liver disease because now I now that half of that carbs in coke is Fructose and only liver can neutralize it which ends up like fatty liver disease.
Who would've thought, eh.
💚🏜️💚 great information
You mean, it is like the problem is not a statin deficiency?
Bro how many shots of espresso this morning lol.
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Follow the evidence son. Apob drives ASCVD primarily. IR smoking high BP are all secondary factors but no Apob no ASCVD progression
so instead of people bypassing the system and trying to go keto or carnivore by not "eating" carbs, people should better find out what is blocking their cells from properly using glucose as fuel...and then they ll find out that they dont need to go keto or carnivore.
One thing that could be "blocking" their cells is just a naturally lower insulin levels, I think that's behind the "hereditary type 2 diabetes". These people tend to be thinner too after all.
I appreciate your conclusion - don't eat processed foods - but "A new study finds Insulin fosters heart plaque build up" makes no sense.You mean insulin resistance - insulin is necessary to push nutrients like glucose into the cells. By the way, there are others who have scientific evidence that fat from all sources gums up the cellular membranes leading to insulin resistance. Look for experts in the whole food plant world like Dr. John McDougall, Dr. Esselstyn, Dr. Peter Rogers.
This is new?
No, just yhe meyhod. It confirms what has been said for many years.
Dietary saturated fat consumption like those from animal products cause insulin resistance. The fat binds with enzymes in the muscle cells clogging them up leaving glucose unable to be deposited into the muscles. This causes blood glucose to stay elevated because it can't be properly stored in the muscle.
So the opposite conclusion of the high fat low carb crowd. Your analysis is apparently the conventional wisdom. Thanks for bringing it to my attention. I became health conscious during the Paleo fad of the early 2000's. So I've mostly studied the positive effects of low carb eating. Not saying that the hypothesis that saturated fat consumption causes insulin resistance is correct. My question has to be about triglycerides. If high triglycerides are indicative of high blood sugar and all inflammatory markers go up when triglycerides are high then how is saturated fat responsible for high blood sugar and the deleterious effects of that?
@@puggirl415 just what I said previously. Dietary saturated fat increases insulin resistance. We have known for decades that intramuscular fat increases insulin resistance.
@@billdublewhopper3064 You just lost credibility. I asked a specific question about triglycerides blood sugar and how saturated fat could be responsible for the inflammation that comes from high triglycerides.
If you don't know the answer that's fine. I won't believe a stranger on the internet just stating shit as if it's a fact though.
Prove your "facts" by answering questions or citing a recent study proving your narrative. Or don't. But no one, including me, will believe you on here if can't prove your assertions or answer specific questions. I don't take on second hand thoughts spouted by ignorant third parties.
@@puggirl415 triglycerides will not cause athersclerosis. A simple 2 second gge search of insulin resistance band saturated fat will explain to you what you are looking for.
Sounds like people with serious heart disease should be taking exogenous ketones until they can change their diet and correct the issues. Won't hurt the brain either...
I guess you don't know what summarizing means. ?
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VACKSSSSSSSSS SEENSSSSSSSSSSS
MOOOOROOOON
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Theres no doubt that diabetes and coronary heart disease go hand in hand. Being diabetic is a risk factor to developing atherosclerosis. However, you cannot deny that there are still non diabetics who develop coronary artery disease. People with normal Hba1c, non diabetics, can still develop atherosclerosis.
They have high insulin levels. Go watch Dr. Ben Bikman for more info
Most type 2's don't know they have diabetes because they don't get fasting insulin tested or don't do an OGTT with insulin. If they did I can assure you that the vast majority of people with cardiovascular disease wouldn't be in a good metabolic health.
They have pre diabetes. Or fatty liver disease. Fatty liver dissease is from high amounts of fructose. Fructose is neutralized in liver but this proces is creating uric acid which is heightening blood pressure. High blood presure is weakening coronary vessels. Such vessels are than prone to develop atherosclerosis which can end up in plaque development especially if are oxidized fatty acids present. First option (pre diabetes) ends up similar. High amounts of insulin are secreted by pankreas to cram sugar into insulin resistant tissues to keep sugar levels in bloodstream close to normal . But high Insulin present in bloodstream make kidneys stop filtering out redundant water and salt which ends up in high blood pressure. And from there it is the same story.
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Please try to talk little slower
Options -> Playback Speed
@@delxinogaming6046 it sounds really weird tried already. Doesnt sound natural. A bit annoying.
It’s a common issue nowadays, people talking faster and not annunciating properly.
You should speak in a way that ordinary people will understand.its usesless,your not explaining,your just showing
Instead of putting statins in the drinking water like doctors were proposing in the early 2000s, maybe start putting metformin in the drinking water? 💦
All have sinned (Romans 3:23 KJV). The Lord Jesus Christ died for our sins, was buried and rose again the third day (1 Corinthians 15:1-4 KJV). Jesus shed His blood for our sins (Ephesians 1:7 KJV). Getting water baptized DOESN'T save us (1 Corinthians 1:17 KJV). We are saved by grace through faith, not our works (Ephesians 2:8-9 KJV). Only Jesus saves from hell
I like turtles
And follow Jesus' commands because we love Him and follow His example. In the context of this video, fast like Jesus. If you're able like Jesus, for up to 40 days. We know based on todays science, fasting will lower insulin resistance and help treat metabolic syndrome in our body, including our heart. Our body is the Temple of the Holy Spirit. Let us respect and love our body like Jesus does because He is one with the Holy Spirit.
Protestant interpretation
@@domega7392 that is what the Bible says. But i know you catholics don't read it or not enough to realize that the catholic Institution is mystery babylon of Revelation 17
1:23 ad nausem. Distinguished phrase
There is no such a thing as “insulin resistance”. So, you are wrong with whatever you were saying. On the basis of a false premise.