David Ludwig, MD, PhD -- Which Comes First: Overeating or Obesity?
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- Опубликовано: 9 фев 2025
- David Ludwig, MD, PhD
Professor of Pediatrics: Harvard Medical School
Professor of Nutrition: Harvard School of Public Health
David Ludwig, M.D., Ph.D. David S. Ludwig, MD, PhD is a practicing endocrinologist and researcher at Boston Children’s Hospital. He holds the rank of Professor of Pediatrics at Harvard Medical School and Professor of Nutrition at Harvard School of Public Health. Dr Ludwig is Founding Director of the Optimal Weight for Life (OWL) program at Children’s Hospital, one of the country’s oldest and largest multidisciplinary clinics for the care of overweight children. He also directs the New Balance Foundation Obesity Prevention Center. His research focuses on the effects of diet on hormones, metabolism and body weight. In particular, he developed a novel “low glycemic load” diet (i.e., one that decreases the surge in blood sugar after meals) for the treatment of obesity and prevention of type 2 diabetes and heart disease. Dr. Ludwig is Principal Investigator on numerous grants from the National Institutes of Health, has published over 150 scientific articles, and presently serves as Contributing Writer for JAMA. He is author of the forthcoming book, Always, Hungry? Conquer Cravings, Retrain your Fat Cells, and Lose Weight Permanently (Grand Central Publishing, January 2016).
I'm not so sure that Dr. Lustig would necessarily "go through the roof," as Dr. Ludwig anticipates. Dr. Lustig is on record as saying that fructose in whole fruits is okay, because the fiber in the fruits slows down the absorption of the fructose to a rate the liver can handle. Also, as he points out, it is _extremely_ difficult to eat as many apples, for example, as it would take to get the same amount of fructose contained in two sodas.
this is one of the best broad explanation yet on RUclips detailing not only the issue of carbs/sugar/storage but also the "Next Bit Thing" which is our bodies, our cells, are indeed in starvation mode while eating a High Carb diet
I can't thank you enough David Ludwig!!!
Brilliant ! I will surely review this lecture. Thanks from Germany.
Thank you for designing your study methodology like an actual researcher! Great information.
Starting at 20:00, a mind boggling description of carb addiction works, and doesn't work. Amazing to know. Really.
@Daniel Pincus
Only the fast-acting (high glycemic index) milk-shake lit up the nucleus accumbens. The sweetness was the same for both shakes.
Once again, the palatability hypothesis is revealed to have no there, there.. (When is Stephan Guyenet going to give up on that nonsense?). ???
I watched this about a year ago, or more. I'm back in here with some different perspectives. I'm now blown away that fast-food can cause addiction (hijacks the nucleus accumbens), not because it tastes good, but because of the metabolic impact of the food itself. That's now a "whoa!?" moment for me. (see around 20 minutes in).
BTW, David Ludwig bought me a nice, quality meal at a restaurant in Charlottesville, VA. Thanks David, I still owe you.
Wish the slides were shown for longer
You could have stopped the computer.
the world should watch all those videos, to start with for all MD's and those on med school it should be compulsary
Very informative presentation! Thank you!
An absolutely awesome lecture!
Very interesting indeed. Thank you.
We are not a closed system
A great talk, but spoiled (like so many talks which appear on RUclips) by not being able to hear the questions clearly. If the questioners were using a microphone, then it was not adequate, but I suspect they were not using one.
Another point: although I'm sure Dr Ludwig is fully aware, the casual listener might go away with the impression that the sugar in fruit is only fructose. This is far from the case: most fruits contain a variable mixture of fructose and glucose, and some sucrose. Fructose is rarely (if ever) found alone in nature (so any study that uses infusions of pure fructose is not imitating nature and may be flawed (depending on exactly what it is trying to show)).
that videographer is lousy--this should mainly be SLIDES and not pics of Dr Ludwig. This person clearly has no clue about how to film an academic conference. it's the SLIDES we want to see mainly, not dr Ludwig! geez!
i thought his presentation was quite good. I'm no doctor but I don't understand why everyone seemed to be so against him when they were asking questions.
they don't like change. they are followers not leaders and they know what will happen if they go back to their colleagues and tell them about these insights. a huge swath of the medical industry apparently has little time for actual science
Most of them are fellow researchers on the low-carb, high-fat bandwagon, so they may be challenging or clarifying certain points, but they are in basic agreement. I recognized Eric Westman, Jeff Volek, and Sarah Hallberg in particular, and there are probably others I didn't catch. So never fear, the majority of the audience was not hostile, even if they were insistent on certain points of difference. It's just normal scientific debate.
I think Dr. Ludwig answered the question "Which Comes First: Overeating or Obesity?" with "The Obesity comes first." Am I right or wrong? It wasn't really clear to me..
I wonder if this approach would be feasible for the 600-lb. life sufferers.
yes for sure
Sugar is the new Tabaco, maybe even worse.
When you say'diabetes'do you mean Type 2 Diabetes or Type 1 Diabetes? When you don't make this clear it can be very confusing