Use the first formula if you have been taught that 1NADH produces 2.5ATP and 1FADH2 produces 1.5ATP when connected to the electron transport chain. Use the second formula if you have been taught that 1NADH produces 3ATP and 1FADH2 produces 2ATP when connected to the electron transport chain. Hope this helps clarify which formula to use. Regards, Wonders of Chemistry
@@wondersofchemistry Yes Thankyou So Much For Your Reply But Can You Clarify My One more Doubt Can i use this formula to calculate how many atp formed from ketogenesis(I.e From molecule Of Acetyl CoA)?
The formula(s) are designed only to calculate the total yeild of ATP for saturated even numbered fatty acids. So just to clarify, you want to calculate how many ATPs a ketone such as acetoacetate could yield during ketogenesis... is that correct?
ok ... So lets assume each of the two acetyl coAs that made up acetoacetate where liberated and used within the citic acid cycle of mitcondria within the peripheral tissues including that of the brain (recall the liver cannot metabolise ketones) ... each acetyl coA would generate 1GTP = 1ATP, 3NADH = 3 X 2.5ATP = 7.5ATP and 1FADH2 = 1X1.5ATP = 1.5ATP. Adding all these up gives 10 ATP per acetyl coA. However, acetacetate breaks down to give 2 Acetyl coA's. Therefore acetoacetate can generate a total of 20ATP. I hope this helps abswer your question. Note my calculations are based the following assumptions 1GTP will give 1ATP, 1NADH will give 2.5ATP and 1FADH2 will give 1.5ATP.
Hi Adrian,Thanks for the comment. If you refer to my following youtube video it will give you a comprehensive understanding as to how I arrived at this formula including the number 6 you are referring to. Hope this helps.
Hi Camille, apologies for the late reply to your question. Please click the following link to my youtube video which explains how the numbers for each of the two algorithms are derived. Be a little patient and watch the whole video as this will really help with your understanding. ruclips.net/video/Erfr7i04WgM/видео.html
The first formula assumes that for every NADH produced this will translate into 2.5ATP and for every FADH2 this will translate into 1.5ATP. The second formula assumes rounded up figures 3ATP and 2ATP respectively. Older text books tend to use the rounded up figures.
Oh my gosh this is amazing. Such a clear and easy to understand video. I feel like I just discovered the biggest trick! Thank you so much.
Glad it was helpful!
But did you notice that it is useful only if we are faced with fatty acids with double number of carbon.
@@fethiennourtennah2968 I mean, it is in the title. So yes, definitely noticed. Lol :D
You made it crystal clear
That was really amazing and useful
But what is the short trick for calculating ATP for odd number of fatty acid
Please do reply 🥺
God bless you. This made it so simple!
Thanks for the formula, don’t forget -1,5 for every double bonds
It was super amazing
But can there be a way for odd carbon numbered fatty acids too
Pls what is the relationship between complete metabolism of one molecule of glucose an beta oxidation of palmitic acid, in terms of ATP production
In status of odd number what can i do???
Ohh God bless you soo thankfull to you....
Thanks a tonn.... Best u are
Mind-blowing Sir
Thankyou very much
Thanks
I was stucked on that point but you made it really fantastic
again thankyou
Thankew so much for this ❤
Sir Can You Please Tell me
When we to use 1 formula or 2nd formula?
Use the first formula if you have been taught that 1NADH produces 2.5ATP and 1FADH2 produces 1.5ATP when connected to the electron transport chain. Use the second formula if you have been taught that 1NADH produces 3ATP and 1FADH2 produces 2ATP when connected to the electron transport chain. Hope this helps clarify which formula to use. Regards, Wonders of Chemistry
@@wondersofchemistry Yes Thankyou So Much For Your Reply
But Can You Clarify My One more Doubt
Can i use this formula to calculate how many atp formed from ketogenesis(I.e From molecule Of Acetyl CoA)?
The formula(s) are designed only to calculate the total yeild of ATP for saturated even numbered fatty acids. So just to clarify, you want to calculate how many ATPs a ketone such as acetoacetate could yield during ketogenesis... is that correct?
@@wondersofchemistry Yes
ok ... So lets assume each of the two acetyl coAs that made up acetoacetate where liberated and used within the citic acid cycle of mitcondria within the peripheral tissues including that of the brain (recall the liver cannot metabolise ketones) ... each acetyl coA would generate 1GTP = 1ATP, 3NADH = 3 X 2.5ATP = 7.5ATP and 1FADH2 = 1X1.5ATP = 1.5ATP. Adding all these up gives 10 ATP per acetyl coA. However, acetacetate breaks down to give 2 Acetyl coA's. Therefore acetoacetate can generate a total of 20ATP. I hope this helps abswer your question. Note my calculations are based the following assumptions 1GTP will give 1ATP, 1NADH will give 2.5ATP and 1FADH2 will give 1.5ATP.
thats amazing.whats about odd no. of carbon?tell please
Hi, thanks for the positive comments. I will endeavour to work on an algorithm that does exactly that in the future. Regards, Wonders of Chemistry
Please make video on Protein Metabolism and it's energy budget
Is there any trick for unsaturated fatty acids
Really nice, thanks. In the formula 7 is for 7 cycles of oxidation-hydration-oxidation-thiolysis (I imagine), but why is the minus 6?
Hi Adrian,Thanks for the comment. If you refer to my following youtube video it will give you a comprehensive understanding as to how I arrived at this formula including the number 6 you are referring to. Hope this helps.
sorry here is the link ruclips.net/video/Erfr7i04WgM/видео.html
Excellent
thanks :-)
LIFE SAVER
where did number 7 come from? Is it a standard number?
Thank you I love you
What about unsaturated
There are 145 molecules of water produced during the Palmitic acid complete oxidation. How?? Kindly, reply.
Great man
So helpful!!
Glad it was helpful!
Good one
Thanks
Thanks
Nice
thanks for the comment
Thanks man
Thank you
You're welcome
Where did the 8.5 came from?
Hi Camille, apologies for the late reply to your question. Please click the following link to my youtube video which explains how the numbers for each of the two algorithms are derived. Be a little patient and watch the whole video as this will really help with your understanding. ruclips.net/video/Erfr7i04WgM/видео.html
First formula-odd number of carbons , second formula-even number of carbons.....am I wright or wrong???
The first formula assumes that for every NADH produced this will translate into 2.5ATP and for every FADH2 this will translate into 1.5ATP. The second formula assumes rounded up figures 3ATP and 2ATP respectively. Older text books tend to use the rounded up figures.
For odd number fatty acids??
Sorry Michael, I have only developed algorithms for even numbered saturated fatty acids. Maybe in the not too distant future.
Use (7*n)-19
Maybe textbooks shouldn't lie to simplify.
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