The David Sinclair $720,000,000 Train Wreck!

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  • Опубликовано: 27 сен 2024
  • This is the story of how Harvard professor David Sinclair's mistakes earned him $720 million, and is using the same strategy to do it again, today.
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    www.ncbi.nlm.n...
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    pubmed.ncbi.nl...
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    www.ncbi.nlm.n...
    www.ncbi.nlm.n...
    HTTPS://PUBMED.NCBI.NL...
    www.ncbi.nlm.n...
    www.frontiersi...
    pubmed.ncbi.nl...
    www.cochrane.o...
    www.ncbi.nlm.n...
    www.ncbi.nlm.n...
    pubmed.ncbi.nl...
    www.uptodate.c...
    www.regulation...
    www.newsweek.c...
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Комментарии • 1,6 тыс.

  • @DrBradStanfield
    @DrBradStanfield  6 месяцев назад +177

    What do you think about the statement from the former Dean of Harvard Medical School at the end of the video?
    📜 Roadmap - how to look young & feel strong: drstanfield.com/pages/roadmap

    • @jozefwoo8079
      @jozefwoo8079 6 месяцев назад +3

      Dr Stanfield, will you be distributing in Europe as well? Currently the customs and transport costs for MicroVitamin are insanely high.

    • @augurcybernaut4785
      @augurcybernaut4785 6 месяцев назад +13

      8:08 😖
      🤔 are we to understand that GSK bought WITHOUT evidence of efficacy? Without replicating ANY experiments? Wouldn’t that imply Sinclair wasn’t the only one “incompetent”?
      What about all those OTHERS advocating for resveratrol ?
      And no I didn’t take the 💉🦠
      🫣Wouldn’t GSK have sought the opinion of his colleagues before or even now to do a “claw back”?

    • @jodihammer
      @jodihammer 6 месяцев назад +21

      @@augurcybernaut4785 right. How can they afford to spend $720M without doing proper due diligence?

    • @srlm8215
      @srlm8215 6 месяцев назад +6

      you also have to have this point of view: if you have to spend thousands for each specific study, it would cost millions, it's not just the studies, I've been taking nmn for 4
      month, when I take it sublingually I immediately feel the effects, there is a boost, the effects are there, there is no denying it, do we have to spend thousands more to show the immediate effect that it provides ?

    • @danielmccarthyy
      @danielmccarthyy 6 месяцев назад +3

      Damning.

  • @lordjim3109
    @lordjim3109 6 месяцев назад +1452

    David Sinclair is by far the worst disappointment in the longevity community. He started as a great hope for so many, and ended up as the embodiment of all that is wrong with modern science: greed and corruption.

    • @loum.4377
      @loum.4377 6 месяцев назад +31

      money grab.

    • @mitkoogrozev
      @mitkoogrozev 6 месяцев назад +34

      That's not intrinsically a problem with science or people, but the fact that we live in a monetary based global society. Money has become a generalized reinforcer. That is, it can affect and control behavior for absolutely all aspects of life since it's been inserted in all of them , while naturally without money different aspects of life have distinct and varied reinforcers instead of a singular generalized one. As such, money has a stronger effect than all others, and/or at least it will always, as long as it exists, corrupt anything and everything it's involved in. And well, it's involved in...everything :D .
      And "corrupt'' is probably not even the right word, since what it does is just an intrinsic property of it's mechanisms. So it behaves as expected (at least by the people who know what to look for, and not be blinded by ideology of how they THINK it's supposed to work) . In other words, the system is not corrupted, it works exactly as designed. Any time you insert a token to replace intrinsic motivation (intrinsic motivation meaning doing a task simply because of it's results, or in other words because you enjoy it/believe that is important etc.) , you introduce a skew for the behavior to be done for the extrinsic motivator - the token instead. And we have just one singular token called money, that can be exchanged for anything and everything put into all areas in life. So naturally, everything will be skewed.

    • @Utoko
      @Utoko 6 месяцев назад +32

      Ye he is a great communicator. Got me interesting in the field with his book+ great interviews and at the same time makes me distrust now every single person in the field.
      Boundless greed is so sad.

    • @lordjim3109
      @lordjim3109 6 месяцев назад +8

      @@Utoko Exactly so.

    • @gugy68
      @gugy68 6 месяцев назад +15

      Sad indeed. I never spent any money on his stuff but was an avid follower of his information and the guy looked extremely credible.
      No wonder all institutions and most scientists in this case are so discredit and looked with skepticism. They dug that whole and honestly I don’t think they will ever regain the trust from the public again.

  • @danpictish5457
    @danpictish5457 6 месяцев назад +88

    Just being from Harvard shouldn't mean anything without evidence!

    • @No-Humans-Allowed
      @No-Humans-Allowed 6 месяцев назад

      Harvard is one of the biggest collaborators with big Pharma. They have published ‘peer reviewed’ fraud to suit their narrative and not to be regarded as a leading light in honesty and integrity.

    • @shellderp
      @shellderp 6 месяцев назад

      they are the ones who admitted to being funded by sugar industry to lie about results. They also recently came out with the hilarious article about red meat being linked to diabetes

    • @alexsmith-gn4tp
      @alexsmith-gn4tp 2 месяца назад +1

      😂❤

  • @mikecain6947
    @mikecain6947 6 месяцев назад +230

    You are very brave to do this video. Thank you and keep them coming.

  • @UsDiYoNa
    @UsDiYoNa 6 месяцев назад +312

    Harvard has really become a joke.

    • @ninefive8930
      @ninefive8930 6 месяцев назад +26

      All of modern academia really is a joke. Back to reading Plato and Aristotle.

    • @LoisoPondohva
      @LoisoPondohva 6 месяцев назад +11

      Harvard has been "not a joke" for a very brief period very long ago.
      People just associate it with being elite because 95% or our billionaires and politicians have graduated from there. But being elite is not the cause of that one, being corrupt is.

    • @oolala53
      @oolala53 6 месяцев назад +2

      @@LoisoPondohvainteresting statistic. Care to say where you found it?

    • @beardfootofficial
      @beardfootofficial 6 месяцев назад +1

      Truth

    • @justrecorded4u984
      @justrecorded4u984 6 месяцев назад +6

      Harvard is hype and doesn't have much contribution to science.

  • @wpmitra7251
    @wpmitra7251 6 месяцев назад +664

    Any time I see Sinclair associated with any supplement or treatment, I immediately stop paying attention to it. I wonder why Harvard doesn't severe ties with him already. Kudos to you

    • @kimberlybarrett5341
      @kimberlybarrett5341 6 месяцев назад +16

      Agreed

    • @googlespies
      @googlespies 6 месяцев назад

      Harvard is beyond corrupt themselves. This isn't the first time and it won't be the last time Harvard has been intwined in blatant science fraud. Search "50 Years Ago, Sugar Industry Quietly Paid Scientists To Point Blame At Fat"

    • @dominikh9526
      @dominikh9526 6 месяцев назад +53

      Same with Huberman.

    • @indiankid8601
      @indiankid8601 6 месяцев назад +21

      Because Money 💰 🤑

    • @slimturnpike
      @slimturnpike 6 месяцев назад

      Goes double for Huberman ​@@dominikh9526

  • @traderalex655
    @traderalex655 5 месяцев назад +34

    As a scientist myself, I'm very distressed about the lack of honesty and integrity in many areas of science. Harvard is a cesspool and an embarrassment to the scientific community. We need a national, independent oversight organization who reports to the public on people like Sinclair. Thank you for making this video.

    • @jimj2683
      @jimj2683 Месяц назад

      Do we? It seems like the fraudsters are being exposed due to the internet. And most people with a brain could tell David Sinclair was a fraud from the beginning.

  • @AncestralFuel
    @AncestralFuel 6 месяцев назад +357

    Finally someone has exposed this fraud. I have heard of bits and pieces of the Sinclair con over the years, but this is the first time I have seen it all tied-up in a single report. Great job Dr Brad!

    • @paulbarclay4114
      @paulbarclay4114 6 месяцев назад +1

      he has a long history of fraud, but the work he is currently doing is game changing

    • @AncestralFuel
      @AncestralFuel 6 месяцев назад

      @@paulbarclay4114 yeah that is what everyone was saying before

    • @peters616
      @peters616 6 месяцев назад +8

      fool me once...

    • @AncestralFuel
      @AncestralFuel 6 месяцев назад +3

      Yeah, I recently saw a study out of Britain illustrating in 65-80 age group they could raise their NAD levels to that of a twenty year old by having them simply walk 13,500 steps a day - Sinclair ain’t talking about this study. 4,000 steps nothing, 8,000 steps were an improvement, but 13,500 was the magic number.

    • @swimbait1
      @swimbait1 6 месяцев назад +1

      There’s hundreds of videos online calling out Sinclair.

  • @elgaen555
    @elgaen555 5 месяцев назад +18

    David Sinclair has talked so many times publicly about how disappointing resveratrol was in practical application. He admitted the failure and kept doing his work. Investors want no risk and all the reward it seems. You’re literally selling a vitamin.

  • @Vincent-fv1ch
    @Vincent-fv1ch 6 месяцев назад +284

    This video needs to go viral!

  • @SrNutritivo
    @SrNutritivo 6 месяцев назад +57

    This breaks my heart. I loved his book and literally re-started my life, took me out of a severe depression, and transformed my life in a positive ways. I totally bought his messianic vision about our future. Hurts so bad that looks like all that was based on a lie 😢

    • @jmonkey1111
      @jmonkey1111 6 месяцев назад +17

      Looks like some of his science checks out as he wasn't the first to research nmn and metformin. The resveritol is the no go it seems

    • @pgc6290
      @pgc6290 6 месяцев назад +1

      ​@@jmonkey1111have they verified the research that he is doing in harvard. He said age reversal pill might come in 10 years.

    • @erikhenze2339
      @erikhenze2339 6 месяцев назад +26

      Don’t be entirely discouraged. He may be somewhat of a snake oil salesman, but he is not only that. His information theory of aging is a very interesting insight and, while still nascent, there is some experimental evidence for it now. But only time (further experiments) will tell if it’s really a breakthrough theory.

    • @DerFlotteReiter
      @DerFlotteReiter 6 месяцев назад +16

      You have changed your life to the better. No one else. Even if the basis were a fraud or a lie: you changed it and you have done something good. I can understand your words better than most people. Believe me. But hold on to those positive changes you have made!

    • @davidogan
      @davidogan 6 месяцев назад +18

      It wasn’t him. It was you who changed your life. Maybe you used his “lie” as the starting point but you walked the road yourself. Even if it wasn’t a lie, and was the absolute truth, you’ll still have to walk the sometime lonely road to recovery on your own anyways. Congrats btw and good luck on your road to success!

  • @abc_cba
    @abc_cba 6 месяцев назад +545

    This man will be an international level threat to David Sinclair, calling him out, the only one who dares who do that!

    • @OperationAndrew.
      @OperationAndrew. 6 месяцев назад +14

      A risky call out to say that his intentions were to trick GSK though

    • @nephilimninjaofnibiru2907
      @nephilimninjaofnibiru2907 6 месяцев назад +11

      For someone who studies lifespan. This seems like a rookie mistake to shorten one's lifespan.

    • @zack_120
      @zack_120 6 месяцев назад +9

      ​@@OperationAndrew.No, he didn't. you got the logic messed up.

    • @davidjordan2011
      @davidjordan2011 6 месяцев назад +11

      In fact, he's not the only one. Marcel James, through his YT channel The Pulse, is doing similar, although he also criticizes the FDA.

    • @abc_cba
      @abc_cba 6 месяцев назад +13

      @@davidjordan2011 well, as for India, Stanfield is a popular name in the health community, so, I'm saying based on my geography and whereabouts and people I interact with.
      That's just why I used the term "international" level. 🤣😅
      RUclips has become a space for misinformation these days, especially fear mongering.
      There are two Aussies, Labmuffin (Michele) and Brad Stanfield who bust the myths and tell us not be scared which people like Gundry, Dave Asprey and a few others use to create furore amongst the "uneducated masses" who barely know any science but just follow fads to stay relevant in this age of Instagram.

  • @bornholm1588
    @bornholm1588 6 месяцев назад +86

    In Germany we also have a that time famous doctor who wrote books about "forever young" with great success in which he claimed he could expand lifespan with lifestyle and nutrition. Now he is almost 80, still alive, but looks just like all 80 year olds I know.

    • @cag1
      @cag1 6 месяцев назад +4

      who is that?

    • @davidogan
      @davidogan 6 месяцев назад +3

      Maybe that famous doctor meant it metaphorically? Like being “forever young” inside?

    • @rajeevshrivastava4488
      @rajeevshrivastava4488 6 месяцев назад +7

      Deepak Chopra is in the same category....

    • @AL_THOMAS_777
      @AL_THOMAS_777 5 месяцев назад

      @@cag1 Dr. Ulli STRUNZ !

    • @philosopher2king
      @philosopher2king 5 месяцев назад +2

      The only "Forever Young" out of Germany was that song from Alphaville and I love it 😁

  • @earx23
    @earx23 6 месяцев назад +142

    Thanks for exposing Sinclair's fraud. At some point I thought he was sketchy. All we needed was some solid proof. Thanks for this detailed review.

    • @earx23
      @earx23 6 месяцев назад +7

      @@fdsfaf132 Come on. Even in the last couple of years Sinclair claimed that his findings were going to lead to extended life span in humans, still hanging on to the supposedly beneficial effects of Resveratrol, which were disproved long ago. He doesn't even admit his mistakes.. just riding the wave to even more money.

    • @HkFinn83
      @HkFinn83 6 месяцев назад

      @@fdsfaf132 you’re not disagreeing you’re using the word legalistically, he’s using vernacular

    • @jacked_asian
      @jacked_asian 6 месяцев назад +2

      When he hyped up autophagy and low protein diets, I just felt very offput by him

  • @andrewtaylor9799
    @andrewtaylor9799 6 месяцев назад +11

    Thanks for publicizing this.

  • @djlouder
    @djlouder 6 месяцев назад +20

    Thank you for staying on top of this subject! I especially appreciate your take on B3. Since watching one of your past vids, I started to take B3. It has helped me immensely! Thanks for all you do!

  • @reuterss306
    @reuterss306 6 месяцев назад +53

    More people need to hear this. To me its mind-boggling how many people are still chugging down absurd amounts of overprized resveratrol. Didn't help that many people praised the studies and talked about it so much on podcasts. Like Dr. Rhonda Patrick on JRE.

    • @comatosebrose
      @comatosebrose 6 месяцев назад +5

      I think I've been conned uve spent thousands of both nmn and resveratrol.

    • @rg3412
      @rg3412 6 месяцев назад

      She knows it’s more lucrative to spit back positive results from one study than to deconstruct the many studies that inundate the papers and whose majority are not reproducible

    • @nichobee
      @nichobee 6 месяцев назад +1

      She annoys me too. I think she means a lot more well than Sinclair, but she also overstates the importance of many individual biochemicals, and in essence she overcomplicates the process of living a healthy and normal life

  • @grahamw453
    @grahamw453 6 месяцев назад +15

    Wow. Thanks Brad for this quality video. You are truly courageous for doing this. Thanks for getting the word out about Sinclairs history.

  • @just-7783
    @just-7783 6 месяцев назад +5

    I follow you since years and have huge respect for your courage!! Keep up your great work!

  • @richardgabbrielli3328
    @richardgabbrielli3328 6 месяцев назад +8

    Great video Brad, thanks for sharing this info as many are still not aware of what Sinclair's doing

  • @thegreaterconundrum
    @thegreaterconundrum 6 месяцев назад +3

    This video is so important! What gives misinformation such power is that scientists and thinkers choose to say nothing about it, wether because they think it's obvious or because they assume people already know. But I love that you're calling him out, and I'd love more videos going into bad research practice and calling out specific papers/individuals for this kind of shady misconduct. No one else is going to do it, and if no one does it it'll just get worse and worse!

  • @Mikolas649
    @Mikolas649 6 месяцев назад +3

    New respect for Dr. Brad, for bringing all the facts, and cutting the BS!

  • @GHFrankie
    @GHFrankie 6 месяцев назад +7

    Thank you for putting the word out! I tried Sinclair's nmn and resveratrol regiment after all that hype in podcasts a few years ago, and it felt pretty obvious to me in the first few days that this can't be good for the human body. This is not just a case of making bank from useless supplements, people can get seriously hurt by what Sinclair's peddling.

    • @diamond_s
      @diamond_s 6 месяцев назад

      Resveratrol has lengthened the lifespan of multiple species including fish mice bees. Studies show it rejuvenates human cells and lengthens telomeres. There is a lot of fake supplements online most of the stuff in amazon is fake. Gsk was mad cause the unpatentable free molecule was better than all the drugs in the market combined.

  • @curtasher9110
    @curtasher9110 6 месяцев назад +8

    Thank you for posting this, Brad

    • @TheMissAnthropy
      @TheMissAnthropy 18 дней назад

      Why does the guy in the video look like he's created with AI? Also the video doesn't look professional, it looks like fraud.

  • @jimmybaker4821
    @jimmybaker4821 6 месяцев назад +10

    Amazing video brad. Love when u focus on the facts and science

  • @buck8055
    @buck8055 6 месяцев назад +3

    Thank you Brad for having the guts to make this video. Hopefully, Sinclair and company won’t use some of their ill gotten gains to try and take you down. Keep up the good fight!

  • @SanctuaryGardenLiving
    @SanctuaryGardenLiving 6 месяцев назад +106

    Doctor Stanfield you are L E G E N D

    • @SilhSe
      @SilhSe 6 месяцев назад +6

      Doc Brad is L E G E N D 😁😁

    • @abc_cba
      @abc_cba 6 месяцев назад

      tu kaha se hain?

    • @SanctuaryGardenLiving
      @SanctuaryGardenLiving 6 месяцев назад

      Good people need other food people 💪🏽🙏🏻

  • @mohammadzaman4919
    @mohammadzaman4919 Месяц назад +1

    David doing deep research and you are promoting your supplements

  • @OdysseuesCotton
    @OdysseuesCotton 6 месяцев назад +367

    Dr. Standfield, I was being critical of your first video concerning David Sinclair, but in the meantime I feel informed well enough to understand better what Sinclair is actually doing. I apologize to you. This video is great and sheds a light on Sinclaire's misdoings. Thanks a lot for that + greetings from Germany

    • @Chaotic313
      @Chaotic313 6 месяцев назад +21

      I was right there with you! I was upset at him throwing shade on a product I was so invested in taking. He stuck to the science and not the hype to the benefit of us all.

    • @LauraPazzaglia
      @LauraPazzaglia 6 месяцев назад +15

      Yes, me too. I feel he has held steadfast and become a better communicator. The early days of defensive tweets and such are gone - I now realize he was very passionate about the topic and took it personally. Now he's letting the facts speak for themselves. Again, good job Dr. Brad!

    • @Vgallo
      @Vgallo 6 месяцев назад +6

      @@Chaotic313 no no you’ve got it wrong, the first accusations were not enough to discredit Sinclair- who after all is the one that came up with the information theory of aging and is a legitimate scientist cited in academic journals all the time, this one accusation was enough to throw shade but not totally discredit the man, especially when you haven’t got the other side of the story, so it wouldn’t of been rational to join the cynical bandwagon at that point, not just based on Stanfield evidence anyway, perhaps if you yourself had insider info, but if you didn’t, then it would of been overly cynical and irrational to join in Stanfield chorus.
      Fast forward to now, with all the water under the bridge and these new accusations and Stanfield initial position seems far more plausible, but only after this added data, not before, so don’t trick yourself into thinking it was any kind of misguided loyalty to a product- I mean did the product work? Surely if anything the efficacy of the product played a larger role on your rationale, or at least I would hope so.
      Regardless, Sinclair is still the creator of the information theory of aging, something the whole longevity field uses, so even if he is a dodgy businessman and a liar, it doesn’t preclude him from being able to contribute valid scientific findings, I mean look at the guy that was part of creating the mRNA vaccine who went around telling everyone it was a massive con when Covid hit, to make money for himself, then when he got Covid and got really sick himself he begged drs to give it to him, does that mean he didn’t do important work that contributed to the amazing mRNA vaccines? Of course it doesn’t.
      Don’t confuse ethics and intelligence. Something Stanfield does consistently.
      Also Stanfield is totally wrong about nad boosters, the fda is studying nad boosters to see if it can be made into an affordable medicine for everyone, they did a similar thing with nac, Stanfield was deliberately vague on all this, all he said was “ Sinclair lobbied the fda” and “ now he’s doing the same thing again”, didn’t explain why the fda is studying nad boosters and when he covered nad boosters on his channel, he excluded all the high quality studies that showed real efficacy of nad boosters.

    • @grellis6483
      @grellis6483 6 месяцев назад +4

      ​@@Vgallo I have a bridge in the desert I think you'd be interested in buying.

    • @Vgallo
      @Vgallo 6 месяцев назад +1

      @@grellis6483 cynicism isn’t clever or rational.

  • @percocetzh
    @percocetzh 6 месяцев назад +3

    Good stuff on calling stuff like this out!Appreciate you Dr. Stanfield keep up all of your amazing work

  • @dcope88
    @dcope88 6 месяцев назад +12

    Great video Dr. Brad. I've always gotten bad vibes when I've seen Sinclair. I am glad to know that my instincts were correct.

  • @carma23
    @carma23 6 месяцев назад +18

    I don’t know if NMN activates sirtuin 1 or not, but there’s no doubt it’s helping me with my chronic fatigue. I would strongly recommend that you don’t paint things black and white

    • @annhughes9912
      @annhughes9912 6 месяцев назад +1

      Yes, my husband and I have noticed a distinct improvement in energy levels on NMN

  • @bigbear7567
    @bigbear7567 6 месяцев назад +21

    Thank you for informing us.

  • @ChickenDinner13
    @ChickenDinner13 6 месяцев назад +9

    This is the best video you’ve ever created… Thank you so much for putting all of this together

  • @ericoshea9382
    @ericoshea9382 6 месяцев назад +7

    Outstanding analysis and extremely well-timed! Hopefully it will inform consumers as they consider “longevity” supplements such as NMN.

  • @jamesleadley7872
    @jamesleadley7872 6 месяцев назад +34

    Hard to believe Harvard isn't investigating this and looking to revoke his position. I know it's a long hard process but it's got to start.

    • @annwilliams6438
      @annwilliams6438 6 месяцев назад +1

      Unfortunately Harvard seems to be having a problem with ethics lately.

  • @andymilkowski7682
    @andymilkowski7682 6 месяцев назад +10

    Thank you for this thorough review.

  • @viveviveka2651
    @viveviveka2651 6 месяцев назад +34

    Thank you for covering this.
    I fell for Sinclair's NMN recommendations. It is the one supplement that really made me nauseated. So I lost a few days to the nausea, and wasted some money.
    Shame on Sinclair, and shame on Harvard. Lesson learned.

  • @mystikrebel1089
    @mystikrebel1089 6 месяцев назад +9

    I see this all as positive in long run because by questioning and critquing everything will eventually will help the /de-aging science longevity science to move forward

    • @bringbackthefiretv495
      @bringbackthefiretv495 6 месяцев назад

      Yes but we hurt in the mean time when people can find something good and buy rights. There were great NMN products but R&D has been stopped by anyone but him because he owns it. It slows things down or stops them when one person can buy and claim rights in a supplement. Same happens with other products like Stevia which used to be healthy and now has additives and you can't find it in its pure form.

  • @wusnheilus
    @wusnheilus 6 месяцев назад +5

    Thank you @DrBradStanfield! Such information is rare on YT.

  • @alfredhammerer3902
    @alfredhammerer3902 6 месяцев назад +4

    Great research and on point ! I had done my own little research on this guy and came to the exact same conclusions. Bravo also for the courage to stand up against this guy !

  • @helge666
    @helge666 6 месяцев назад +78

    Personally, I've been getting a Snakeoil vibe from Sinclair for years. Didn't even finish reading his "Lifespan" book, because something feels off with it, too. Can't even put my finger on it. I've talked to others about it, but nobody seems to agree with me. However, I trust my own BS detector, and it's buzzing when I see the good Professor talk.

    • @zozzrc
      @zozzrc 6 месяцев назад +16

      Yes, this.
      Sinclair does not talk like a scientist. He often speaks in absolutes and seldom qualifies his statements with the key phrases of "needs more study", "we need to be careful not to extrapolate etc.'" He almost never cites other studies and often relies on antidotes . After listening to thousands of hours of longevity podcasts one begins to sense when someone is interested in science vs someone who is interested in marketing. People who are imprecise in their language are usually imprecise in their work. I love youtube , but I try always to keep in mind this Feynman quote "The first principle is that you must not fool yourself and you are the easiest person to fool."

    • @larsnystrom6698
      @larsnystrom6698 6 месяцев назад +4

      That book was too much fiction for me. Ideas put forward as if it were science, but very little scientific support for them.
      Much like he nowadays claim that cells has a epigenetic "backup copy".
      It's not easy for real researchers to debunk the claims of a charlatan with too much media support.
      Harvard seems to like that kind though.

    • @Crowgirl22
      @Crowgirl22 6 месяцев назад +3

      Me too, I always got a bad vibe from him, yet everyone always touted his work

    • @catb4918
      @catb4918 6 месяцев назад

      I agree! I never liked him & thought it was all B.S.

    • @ronjon777
      @ronjon777 6 месяцев назад

      I felt the same way and stopped following him after a while.

  • @scififantasygirl
    @scififantasygirl 6 месяцев назад +1

    Now I’m even more grateful for your channel.

  • @nicksutton2964
    @nicksutton2964 6 месяцев назад +102

    Slippery Sinclair and his Sirtuin

  • @LauraPazzaglia
    @LauraPazzaglia 6 месяцев назад +2

    Well done, Dr. Brad. I have watched you from the beginning and you have finely crafted and refined your way to communicate key issues, as well as taking a stand and not just talking the talk but walking the walk (with your supplement). I appreciate your sharing your expertise in such a concise fact-base manner . Thanks to your videos I have lowered my Vitamin B complex supplement from one that contains 1000%'s of the daily values to a more reasonable amount. Ciao from Italy, L

  • @attila_kosa
    @attila_kosa 6 месяцев назад +95

    Many of us have known for years that David is one of the most incompetent and unethical people in the longevity space. He really should be arrested and charged for what he has done to companies and their innocent investors, and for placing so many lives at risk.

    • @Drgluee
      @Drgluee 6 месяцев назад +3

      I agree. Many of the big investment firms that provide retirement plans invest in pharmaceutical companies.

    • @attila_kosa
      @attila_kosa 6 месяцев назад

      @@Drgluee Exactly, it seems David doesn't care about the poor victims and their retirement plans seeing they had invested into the companies that David tricked.

    • @JoeRogansForehead
      @JoeRogansForehead 6 месяцев назад +7

      “Innocent investors”😂

    • @attila_kosa
      @attila_kosa 6 месяцев назад

      @@JoeRogansForehead Yes, there were a lot of innocent investors into GlaxoSmithShine who lost a LOT :(

    • @TheDavidlloydjones
      @TheDavidlloydjones 6 месяцев назад

      @@Drgluee
      That doesn't make any sense at all, clueless Gluee. Life extension is the last thing people who "the big investment firms that provide retirement plans " want.
      If I were them, I'd be investing in driverless busses. Glider clubs for over-40's. Radical new forms of Scuba gear.
      And especially the famous balsawood fire escape. "Avoid the clanging sound of peole running out of your building." "Rustless protection!" "Even faster from the upper storeys!!!"

  • @SharonPitman
    @SharonPitman 6 месяцев назад +1

    I applaud you for putting yourself out there 👏🏻 Without people like you, we are none the wiser. After I came across your videos a while ago, I immediately stopped taking many of the hyped longevity supplements and saved myself a lot of money. I love simplicity, I love common sense and your videos just resonated with me. Thank you, again, Brad. You are making a real difference by creating some clarity to such complex topics and oftentimes ambiguous data. You’re awesome 🙌🏻

  • @mac2658
    @mac2658 6 месяцев назад +40

    Four years ago Sinclair with his scientific credentials and his father's wonderful story of second youth convinced me to buy alot of nmn, metformin and resveratrol, I took it for a couple of weeks and gave me headaches, I threw it all in the garbage can. Eat well, exercise, manage your social and mental health, that's it.

    • @HkFinn83
      @HkFinn83 6 месяцев назад +4

      Maybe that’s the best you can do now, but hopefully there will someday be a supplement that really does work. If not there isn’t much hope for the longevity field, none of the diets seem to do much beyond what just being moderately lean do and exercise, while good, is difficult to link with any real profound results

    • @dencentbeatz794
      @dencentbeatz794 6 месяцев назад +1

      @@HkFinn83living that healthy lifestyle is proven to really help you live longer and healthier.

    • @HkFinn83
      @HkFinn83 6 месяцев назад

      @@dencentbeatz794 yes I know obviously. In the longevity space we are looking and hoping for something more significant than the marginal life expectancy impacts that have been demonstrated by certain diets/calorie restriction and vo2max training etc. and of course a molecule that actually works is our main hope.

    • @HkFinn83
      @HkFinn83 6 месяцев назад +1

      @@dencentbeatz794 yes obviously, and those us who practice calorie restriction and try to increase our vo2max etc and are hoping for something more significant and that has actual profound longevity impacts, a molecule that actually works is our main hope.

    • @paulharrisonadventuregearm5457
      @paulharrisonadventuregearm5457 6 месяцев назад +3

      Not quite as simple as that I'm afraid. Sinclair wasn't even the person who discovered the longevity health benefits of all those. There is other totally independent research that backs up the benefits that have nothing to do with Sinclair.

  • @tracyau9122
    @tracyau9122 6 месяцев назад +2

    Wow. I wondered when someone would comprehensively put it all together. Thankyou - great piece!

  • @brendant3979
    @brendant3979 6 месяцев назад +17

    Great informaion, thank you

  • @rosey_josh
    @rosey_josh 6 месяцев назад +3

    I used to read and follow Sinclair until I discovered Dr Brad Stanfield. 😊

  • @marcjames3487
    @marcjames3487 6 месяцев назад +61

    Hopefully all the other influencers will stop giving him space to aggrandize himself. One thing I've learned in business over many decades is never deal with people who lack integrity. I spotted that fatal flaw in David Sinclair from the beginning. Kudos to the academics calling him out.

    • @olddouchebag
      @olddouchebag 6 месяцев назад +7

      Influencers thrive on having all these health grifters on their podcasts.

    • @kathleen9456
      @kathleen9456 6 месяцев назад +4

      The Pulse has basically made his entire channel around NMN 🙄

    • @Livelovelaugh684
      @Livelovelaugh684 6 месяцев назад

      @thepulsechannel is piggy backing his 15 minutes of fame around the hype of nmn. He can’t back down now. He feels relevant with the attention he’s getting. He disappears otherwise.
      For the record. I mix in nmn with other supplements. But I’m realistic about its use. It simply cannot and doesn’t do everything he claims it does on his channel. His anectodal claims are out of control.

    • @pcaul8156
      @pcaul8156 6 месяцев назад

      He's just one more grifter in a circle-jerk sea of narcissistic podcasters who pick a niche and try to bleed it dry of cash

    • @upstar21t
      @upstar21t 6 месяцев назад +1

      How'd you spot it?

  • @JosePerez-pn3ke
    @JosePerez-pn3ke 6 месяцев назад +1

    Thanks for ur steadfast commitment to protect ur audience!!

  • @Sjs9000
    @Sjs9000 6 месяцев назад +104

    GSK getting hoodwinked for $720 million is pretty funny

    • @wx2999
      @wx2999 6 месяцев назад +14

      Not really when that money could have gone to curing cancer or something

    • @Sjs9000
      @Sjs9000 6 месяцев назад +27

      @@wx2999or more likely in the pockets of execs, don’t be naive.

    • @frysebox1
      @frysebox1 6 месяцев назад

      @@wx2999 big pharma getting scammed is ALWAYS funny
      why the fuck would they want to cure cancer? none of the money would've gone towards that for obvious reasons

    • @Al-Storm
      @Al-Storm 6 месяцев назад +2

      And the average people that bought into it, desperate for sleeping that worked.

    • @Coromi1
      @Coromi1 6 месяцев назад +11

      Pharmaceutical corporations don't spent theironey on curing cancer. Their profits are high and progress in helping cancer patients is very low. They spent their money on corruption, marketing and buying small companies who own a cash cow.

  • @bradd5961
    @bradd5961 6 месяцев назад +2

    It's super important to get the word out about this. No doubt he'll keep enough for himself while everyone else is excluded.

  • @russeldeakin8792
    @russeldeakin8792 6 месяцев назад +7

    Great job, I typically complain about your take on nmn and intermittent fasting because I feel like I have benefited from both. I do want to appreciate your strictly scientifically proven approach to health, I hope some of more the anecdotal science can expressed in a more formal way so we can get good advice with a lot less cost and more samples to learn from. Thanks for your take on David Sinclair, he is a real snake.

  • @rolfschuttenhelm3462
    @rolfschuttenhelm3462 12 дней назад

    Absolutely fantastic piece of science communication and service to society. Hats off to you Brad, for this video. (And what a world we live in - from the marketing reach of all these lifestyle influencers to the depth of academic rot at Harvard.)

  • @sallypilcher6761
    @sallypilcher6761 6 месяцев назад +50

    Looks like Elizabeth Holmes transitioned and is calling herself David Sinclair!

    • @canesugar911
      @canesugar911 6 месяцев назад +4

      David has been running this scam since lizzy was in highschool

    • @astar1147
      @astar1147 6 месяцев назад +2

      lmao

    • @pgc6290
      @pgc6290 6 месяцев назад +1

      But as soon as someone makes unreal claims, shouldnt they be most highly scrutinized. He has been in public eye since yearrrrrrssssss.

  • @karldean2
    @karldean2 6 месяцев назад +1

    Thank you for keeping it real. You are my go-to doctor for health advice.

  • @mjs28s
    @mjs28s 6 месяцев назад +4

    What is amazing to me is that with a buyout that large they didn't require them to prove their testing with another test done with the company that was wanting to buy them out.
    Non-disclosure and the patents would protect Sinclair's scam from being ripped off.

    • @JohnnyMagorish
      @JohnnyMagorish 6 месяцев назад

      Probably blinded by the Harvard name, but yeah with such a price you’d expect more due-diligence

  • @brendafosmire6519
    @brendafosmire6519 6 месяцев назад

    Thank you!!!! Much needed telling of this ‘story’.
    Those researchers who rush science to their own profit so often get later shown to have over simplified their finding.
    And the pharmaceutical profit hunters don’t care about outcomes, they only care about what will sell.
    THANK YOU! Your summary is excellent with detailed flow of events with references.

  • @Physionic
    @Physionic 6 месяцев назад +12

    What a story - thanks for sharing.

  • @robsherwood5065
    @robsherwood5065 6 месяцев назад +1

    I have spent thousands of dollars based on sinclair's recommendations. Doctor Brad.I truly appreciate you exposing this.

  • @deel2435
    @deel2435 6 месяцев назад

    Don't let the haters get you down Dr Brad! Keep up the great work.

  • @sverkermansson1744
    @sverkermansson1744 6 месяцев назад +7

    Thanks for your research 🔬 🎉

  • @gospelofthomas77thpearl22
    @gospelofthomas77thpearl22 6 месяцев назад +2

    Thanks for your honesty. Much appreciated 👍🏼

  • @LidiYaFilms
    @LidiYaFilms 6 месяцев назад +7

    thank you for your great work

  • @christianer7802
    @christianer7802 5 месяцев назад +2

    Very informative. Can you do a deep dive into the NMN world? It's hard to know what or who to believe.

  • @danielmccarthyy
    @danielmccarthyy 6 месяцев назад +5

    Although I disagree with Brad on statins, I applaud this excellent video.

  • @carlabarber8944
    @carlabarber8944 6 месяцев назад

    You’ve just reminded me to add Sinclair’s book to the bin going to the street tomorrow. Thanks for how you’ve laid this all out for us!

    • @schrittmacher1787
      @schrittmacher1787 6 месяцев назад

      Can you send it to me instead? I'll refund you the shipping costs.

  • @chefty88
    @chefty88 6 месяцев назад +1

    Love your content Dr. Brad, keep up the good fight and don’t be deterred by the machine. Stay independent and realistic.

  • @Mom_Luvs_Tech
    @Mom_Luvs_Tech 6 месяцев назад +5

    Thank you so much for this.

  • @gryphonschnitzel7140
    @gryphonschnitzel7140 6 месяцев назад

    Thanks for your videos and effort, you truly are doing humanity a great service by doing what you do. S tier youtube channel.

  • @Pixel-junkies
    @Pixel-junkies 6 месяцев назад +5

    When I saw Matt Kaeberlein resign my thought was 'gosh guys finally'. It took awhile but finally a few people are speaking out who are around him doing similar work. I am glad to see some movement, but at the same time it sure did take awhile. Still part of me just wants to think Sinclair is plain old incompetent because it upsets me more to think someone would intentionally mislead people to this level. Anyhow about time....

  • @ili626
    @ili626 Месяц назад +1

    Universities should end tenure status. I had a professor at UVA who was tenured, and he was awful. He was held accountable for academic bullying, but all the university could do was place him on indefinite leave.. so he still received a salary for not working. Tenure is just unchecked power

  • @patriciastark7292
    @patriciastark7292 6 месяцев назад +2

    Thank you for your courageous post!

  • @LjudmilaLevy-ml8dh
    @LjudmilaLevy-ml8dh 5 месяцев назад

    Thank you for your research, Dr Brad; people need to hear this information.

  • @jonathanantoine4962
    @jonathanantoine4962 6 месяцев назад +1

    Thank you for your courage and ethic

  • @BCIQW
    @BCIQW 6 месяцев назад +2

    Thank you for making this video!

  • @texastexas4541
    @texastexas4541 4 месяца назад +1

    Sinclair is actually getting younger as we speak. A year ago, he said his body and brain were around 13 years old according to his metabolomics and other tests on sirtuins and MTOR levels. Now I think he is like a toddler inside but with a larger body that weighs around 100 pounds because he eats only once a day (no meat).

  • @DavidMM255
    @DavidMM255 6 месяцев назад +9

    This comment is for raising the awareness on the information brought by this video

  • @lorainisrael
    @lorainisrael Месяц назад

    Thanks for summarising.

  • @serge747b
    @serge747b 6 месяцев назад +5

    Harvard is the gift that keep on giving....

  • @jamiesaari
    @jamiesaari 6 месяцев назад

    You have soooo much courage and are appreciated more than you know. Thank you 🙏

  • @miltonmartins8217
    @miltonmartins8217 6 месяцев назад +6

    very informative!! great video!!!

  • @rayfalciola6163
    @rayfalciola6163 6 месяцев назад +2

    "...Wall of Incompetence..." 🤣🤣🤣 I think you've stumbled into the paradigm of the future.

  • @Number1TravelGuru
    @Number1TravelGuru 6 месяцев назад

    Thank you very much for this video. It has been needed for far too long. Too many people have placed blind faith in this charlatan. His bona fides come from the fact that he is a tenured Harvard professor. I haven't heard a direct attack on Dr. Sinclair's work previously, certainly not from anybody with credibility like yours. I appreciate the work you do!

  • @ConstanzeC
    @ConstanzeC 6 месяцев назад +15

    There is no shame in being wrong in science, it means gaining knowledge. But it is a shame not to respond to critical questions like yours and to simply dismiss them as "horse shit"!
    The fact that people accuse you of falling for Sinclair when the whole world has fallen for him means nothing but a lack of overview.

    • @jonathanantoine4962
      @jonathanantoine4962 6 месяцев назад

      Dude wrote a book couple years ago to say NMN gives period back to an old woman, he is complete fraud, this is not about being wrong in science

  • @kellicardaras2805
    @kellicardaras2805 6 месяцев назад +1

    Excellent and important video! Thank you!

  • @sorenostergaard
    @sorenostergaard 6 месяцев назад +10

    Thank you Brad. This is an absolutely essential video you have made. It is very very problematic that a Harvard professor is essentially driven by money and fame and serious science. But we live in an age where the smart and dishonest people laugh all the way to the bank.

  • @brianremer3248
    @brianremer3248 3 месяца назад +1

    Thx for telling this story

  • @davidbelanger2717
    @davidbelanger2717 6 месяцев назад +4

    Thank you ❤

  • @ilevitatecs2
    @ilevitatecs2 6 месяцев назад +2

    oh boy. this is going to blow up.

  • @LAMPSSSSSSSSSSSS
    @LAMPSSSSSSSSSSSS 6 месяцев назад +8

    Thank you, Mr. Stanfield!

  • @jcgmba98
    @jcgmba98 6 месяцев назад

    “Walls of incompetence “….outstanding!

  • @emileimilheitor3456
    @emileimilheitor3456 4 месяца назад

    The frustration from people unwilling to do what it takes is actually amusing

  • @loum.4377
    @loum.4377 6 месяцев назад +6

    Thank you for taking this on and calling out bs!

  • @machampioninvestments4242
    @machampioninvestments4242 6 месяцев назад +1

    Nice work. A lot of us once trusted Sinclair.

  • @martinzubero9526
    @martinzubero9526 6 месяцев назад +4

    How about that…a pharmaceutical company got bamboozled?😂 Good job Sinclair 👏🏽

    • @muhammadalieesaa3379
      @muhammadalieesaa3379 6 месяцев назад

      I agree, I think they tried to attack Sinclair because he's a threat to big pharma. I read a review of someone who ordered NMN supplements & since taking them he recovered from his C vaccine injury, if that's the case it's no wonder that the pharmaceuticals don't like it. The Gates Foundation have their hands on GSK.

  • @jamesoommen
    @jamesoommen 6 месяцев назад +4

    May be a PR job by GSK. Am I to believe that all the other products (vaccines and drugs) by this company went through the same risk/ benefit analysis?

    • @muhammadalieesaa3379
      @muhammadalieesaa3379 6 месяцев назад +3

      I didn't take the vaccine myself but I do know a lot of people who did & regretted it afterwards because they didn't feel the same since.