What is Baffling Researchers about Ozempic
![Dr. Boz [Annette Bosworth, MD]](http://yt3.ggpht.com/WfdlK4hAtLXN0pbNT1UGRBAe53Vw5hmmlAuyvVV_OUs2FctDCAR2Ot0byG4T8N5Ux04V8wgWZSk=s48-c-k-c0x00ffffff-no-rj)
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- Опубликовано: 9 май 2024
- Research suggests that Ozempic has some positive effects on the brain. But is it worth it?
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It is far better to not be on any pharmaceutical product long term. Only use as absolutely necessary.
Okay, so, I had a binge eating disorder. it was tied to stress and needing comfort. I went on Ozempic as treatment for daily migraines (yes, it helps some people with that), and the side effect was suddenly not thinking about food all the time (this was before the Ozempic craze).
I started losing weight. My insulin sensitivity improved and, as a result, my efforts to lose weight had an effect.
But I knew I couldn't stay on it. I knew I would need better coping mechanisms for the future. So I asked myself, well, if I couldn't eat, say I had surgery the next day and suddenly got stressed but I'd been told not to eat beforehand, what would I do to ease the stress instead?
And so while taking Ozempic, I used that time to deeply look into the reasons why I use for food comfort, what I can do instead, and develop strategies.
Now, a year after being off it, 30kg lighter, I have maintained my weight and my healthy lifestyle. I make a cup of tea when I feel stressed, or watch stand-up comedy. I still get stressed, because it's not possible not to, but I have better coping mechanisms now, and seek dopamine through things like reading, comedy, or seeking out hugs when I need one (and I am NOT a hugger).
It can be done but you have to allow the person time, and they need access to either therapy or some good RUclips videos or just self reflection, but they need to be aware of what causes the eating disorder and that they can and do have the power to live differently. But it absolutely can be done.
Ozempic changed my life because it allowed me the space in my mind to do that for myself.
Interesting! Smart that you were able to create a personal strategy, not to continue the use of ozempic. 👍🏽
What wisdom. Most people don't realize they're empowered to take control.
So u lost a 100lbs! Good job! Get back on it
Most people won’t be like you they will not do the inner work as they weren’t even able to lose the weight in their own. I see it as a ticking time bomb, you didn’t learn to control your mind, tongue and your stomach so it’s inevitable they will make you fall again
Thank you for sharing your process and insight that a pill is not always the solution. However, your experience begs the question, is it true that folks are not supposed to go off ozampic because their metabolism is no longer the same?
I lost 40 pounds on a liver detox based first over about 4 months. Went from 215 to 175. I’m 6’ tall, athletic build. I maintained that weight for 2 years until I began intermittent fasting, one meal at lunch with protein bars/drinks for other meals. Dropped down to 150 after fasting on/off for 3 months. Body fat percentage at around 10%. I also take multivitamin, probiotics, B12 and nitric oxide supplements. I am now going to the gym to rebuild to a healthier weight/physique through weights and a balanced diet. I’m 64 and feel great!
I was tired of bad news every 6 months for my metabolic checkup. Left the Doc’s office & decided if eating too much made me fat, the opposite had to be absolute. Toyed with intermittent fasting and chose Carnivore/one meal per day. Lost 60 lbs in 8 months and have maintained my weight at 205. I am very happy with that. No more diabetic med’s, now have a normal glucose level.
It definitely helped me enourmously with bulimia and the urge to binge has disappeared
That’s why I’m taking it! I need to stop binge eating. I don’t care if I loose weight I just want to stop binging
Natural is the way to go. Pills may help, but there's a cost. Nothing is free when it comes to a pill. The problem is we don't always know the true cost.
Since going carnivore I have lost all desire to drink alcohol. Last week I had a glass and a half of Red Wine with my brother in law ( 1st time in over a year) and I totally felt horrible afterwards, attitude and physical feeling, and firmly set my resolve to totally remove it from my life.
It’s not due to the carnivore diet, you’ve just changed in various ways. I decided to go vegetarian and I also lost my taste for alcohol. One doesn’t cause the other,
My 50-year, robust drinking habit vanished over five years of keto/IF regimen: no will-power required.
Very helpful video, thanks. I especially appreciate the shorter videos😊
I used ozempic for almost two years and lost almost two hundred lbs. when I stopped taking it, my carb cravings increased significantly and I gained 100 lbs in 6 months.
So now u can learn to eat so carb need goes away
No more drugs needed
And permanent fat loss
were you stressed? I mean why would you gain back weight, you did not want to be fat, right? You knew what you were doing, but why did you do it?
Makes no sense at all to get that fat twice..
Go back to your doctor.
You just didn’t eat a lot and then lost a fuck ton lean body mass. Ozempic fasting is the same as normal fasting.
I tried Ozempic for 6 months. I was sick as a dog for 6 months. I couldn’t get out of bed for 6 months. I never lost a pound. I stopped taking Ozempic.
Should have taken your body's Red Alerts more seriously. Been there, but took my body's warnings to heart , please take care. ❤
Why did it take you 6 months to realize that?
@@808BJJ_Black_Belt because the friends and family that I had who were taking it said that eventually that feeling went away for them. My Doctor said the same. So I stuck it out. I also paid a shit ton of money for it and I felt bad that I had to waste it. How does that work for you?
I went back to the Dr. and he mentioned the crazy cravings. We are working on it. Dr. Boz has helped me with the videos and my family has transitioned to Carnivore. Updates show be promising.
I lost my desire to drink! That's the only thing I could think of to tell people why I don't drink alcohol anymore, it's been 10 months now and still no desire. A 59 year old life long beer and booze enthusiast with a brewery in my garage just stopped. I lost 60lbs on Atkins, Keto, Ketovore, Carnivore. I'm thinking carnivore may have been the trigger for the loss of desire for alcohol.
I was a "foodie" and loved swinging down beer. There's more to life! I quit drinking and don't depend on food for entertainment.
Thanks Dr. Boz. Love this content 💕
Thank you dr Boz, interesting valuable knowledge
Very interesting. Thank you for sharing.
you have to change your habits. if you go back to what you were doing before, you're going to go back to where you were.
EXCELLENT information!
Good to know
Thanks sis
My sister is on this. She never tried Keto. To scared of doing any diet except for the ones the ones that the doctors recommend. I have tried to talk to her but she’s not willing to give up carbs. She has not lost a lot of weight on it.
Sounds like my sister. She is losing weight, but extremely slowly. Regardless, she's happy with it so far.
Very good thinking.
Zepbound killed all noise. I only needed to lose 10 pounds, but my binge eating disorder made it very hard to lose weight. Nothing has freed me like this drug. I am quitting this month, after three months Hoping the 10 pounds stay off and my already good habits remain and that the bingeing can be kept at bay.
Wow, how did you manage to keep your weight in check with BED? Any tips? 😂
@@Puglover130 during Covid my mother died and in 2022 my father died. I gained a lot of weight in 3 years. Lost 12, but the remaining weight just stayed on...the 3 months of Zepbound was enough to quiet the noise. I'm perimenopausel, so being very diligent and then binging proved unsuccessful. This drug is a blessing and my hope is to never need it again.
Oxempic can lead to severe depression and muscle loss.. possibly B12 deficiency!
We need to Find better solutions !
It also makes u lose bone mass
N when u gain back fat, it goes to weird places
The muscle loss is your body consuming itself because it lacks calories and protein. It happens on all diets with significant weight loss.
I took the low dose of ozempic for six weeks. Was nauseous most of the time, with indigestion some of the time. Then I started feeling sad and lethargic so I decided not to increase the dose and stopped it altogether. It did help me control hunger and cravings but I did not lose a single pound. I need something that really works.... without all these side effects.
Ozempic didn't work for me. I woke up ravenous at 4 am. I gained 6kg in 4 months, so I gave it up. The second week off the shot, I ended up in bed for 3 days with joint and muscle pain so severe that it was better if I didn't move.
I ended up with fibromyalgia diagnosis after several weeks of seeing the doctor and tests. Got Duloxetine as a medication to help with the nerve pain. Fun and games, sigh!😢
Yeah
This is not a med to be on
I completely lost my desire to drink on Ozempic. Without going into my history, I've come to believe that alcoholism is in its largest parts a metabolic disorder.
Of course there is a somatic element to cancer and a behavioral component to alcoholism, but I think the mitochondria rule the school with both.
The problem is your brain is made of many fats, and if you reduce that you might reduce brain volume. Why not just restrict calories, fast, and exercise, .. it works. I especially recommend don’t eat anything between dinner and breakfast… works wonders.
I take Ozempic for 1 year now - my Wife says my memory is really terrible .
Brilliant.
It made me not want to drink alcohol or overeat for a while, but now that I have been on a whole year, it doesn't have much of any effect at all on my appetite or desire to drink. It's not that it makes you sick to think about food or liquor. It's more like it makes you not care one way or another. Like I said, it worked great on me for about 3-4 months. I still take it hoping it's doing some good for my insulin and blood sugar, but I haven't lost any weight in a long time after losing 30 lbs in 3-4 months.
Ty
That’s exactly right.
I lost the desire to drink but I'm not on Ozempic and I'm not heavy by any means. I do work hard to maintain my physical health
Excellent vid! That graph of cocaine and GLP-1 is very telling. Less perceived reward from what previously provided rewards. Interesting!
Fortunately Keto worked for me. Lost 40 pounds in 11 weeks.
Does not Ozempic and similar also damp down dopamine response to healthy reward seeking?
Dr. Boz, I have read Metformin increases GLP-1 Secretion similar to Ozempic, Trulicity and Wegovy and others. Do you have any thoughts on this? Thank you.
@drboz
That diagram is really cool, demonstrative and informative, much obliged!! Guess that's why Dr. Chopra studied Endo... but does this mean, if I take Ozempic, I can never catch a buzz?????????????
Took it for 2 months for recent diagnosis of Type 2 diabetes and lost 20 pounds, but the side effects were horrible. Diarrhea and gas at both ends that was just unbearable. Couldn’t hardly go out in public because of the odor, and as a pastor that’s not doable.
You should be wary of anything from the pharmaceutical industry aside from antibiotics and natural opiates.
Ummmm….why weren’t woodworking and fishing listed among the pleasures our brain seeks? I’m a tad concerned. 😂
Just started Ozempic, and am doing great getting back on track with ketosis. I had great DBR last fall in the 21DMK, but, of course life happened and my hijacked brain straight back to its old ways. Haven’t been able to get back there as much as I have tried. Felt defeated, like maybe I didn’t want to try again. I saw your video about your DC friend and I felt like it was you giving me permission to try out Ozempic. Thank you!! Can’t wait for some inflammation to be gone!
the easy way is never the best way, do Keto and be strong, you can do it!
I’ve been on Mounjaro for 2.5 months. I’m a big believer in Keto. It’s been my go to since it was Atkins. So naturally I thought this would be a great way to do Keto. The weight slowed greatly after the second week to a crawl. I found some research on how eating carbs is not only essential on these drugs, but also going too low carb on it can do long term damage. I added a little carbs like Japanese sweet, a little fruit daily, beans and lentils and the my weight loss kicked up greatly. Food for thought!! Good luck to you. I’m down nearly 40 lbs!
@@jimbeaver27 I’ve been working keto for about 5 years, but the carb addiction is way strong. The battle in the brain has not let me make it to the 6 month point without a fall. I’m hopeful that the Ozempic will help me with the “food noise” so that I can gain success and some brain healing. Once I get some brain healing, I’m hopeful to get off the Ozempic. If you don’t understand severe addiction, you won’t understand me. Addiction can be managed with abstinence in many cases, but 40 years of addiction is pretty severe. I didn’t understand it as addiction until 5 years ago. When it’s this severe, the battle in the brain is relentless. It’s no longer just about willpower.
I'm on Ozempic for 10 months and it has worked wonders in controlling my blood sugar going from an A1C of 8 to 6.4. I lost no weight the first 6 months but once I started the 1MG dosage in January 2024, I lost 25 pounds as of May 2024. I did count calories and portions but the medication reduced my appetite a little to make it easier to diet. No I've stopped losing so my Dr is going to raise me to max dosage 2MG during the summer.
Will you come back on here when severe damage has occurred and you exclaim you "don't know why?"🙃
@colbyrulesmydoggie4839 such negativity. My endocrinologist has been using Semiglutide on patients for 20years with great success. Ozempic did not exist then but they had been in use in smaller dosages it's not new...
@@edgaracevedo9658I’m glad to hear it’s helping you! The drug has other benefits such as reducing the risk of dementia, etc. However, please be aware it can lead to significant muscle loss in addition to the desired fat loss. This can be minimized by ensuring appropriate protein intake, resistance training and taking a supplement called Creatinine. It’s well tolerated and has an excellent safety profile. Please speak to your doctor about this issue and before taking any supplements. I wish you the best of health.
Dr. Boz, I have a question. If dopamine is down-regulated on GLP1 meds, is there a chance that natural dopamine responses to pleasurable activities could be muted as well?
I'm wondering if it's only in the teenage years, or if their are other factors. I had a normal weight till my forties, but then the over eating began Using a combination of traditional diets and fasting, I was twice able to lose the extra pounds - about 50 each time.. They stayed of for 2-3 years before creeping back. Now I'm easing into Keto.
What lies ahead after these drugs, are there long term issues that are not yet apparent?
Very interesting, see dr Gabor mate. Past trauma and brain reaction system is not enough investigated. The guy microbiome has my interest too.
I take OXcarbazepine as a mood stabilizer because I'm most likely Type 1 Bipolar. I wasn't really trying to stop taking drugs(both kinds), drinking, or smoking cigarettes but that's what happened when I started taking it. Two years in I realized I needed to get into therapy and "do the work". These drugs that deal with executive function are a black box. I'm still on mine but six years in I regret not taking things like talk therapy more seriously ten years ago. I might not have ever needed a mood stabilizer. All the benzos were probably not for the best. SSRIs probably aren't good for most people but they accelerated my cycle and changed my life permanently.
Dr. Boz's Allulose Ice Cream question: Is Coconut milk in the recipe from a can (mostly fat) or from a carton (mostly water)?
You mentioned we recycle our neurotransmitters. I have a problem with repletion not being about to keep up with depletion. How do I mitigate this issue?
I also have pan ulcerative colitis and pan hypo pituitary. I have a GLp1 deficiency along with an endorphin deficiency due to chronic pain secondary to hypermobility type ehlers danlos syndrome.
I work out/do therapy 5 hours/day. I don’t sleep much due to pain and eating and working out are the only two places I get pleasure. When I was 12, I was sexually abused by my mom’s brother and I became anorexic and learned to binge eat as a coping mechanism. This video explains why food is still my go to comfort drug. I am dairy free carnivore for 5 years now and I still struggle with the addiction to the behavior of eating. Any suggestions?
That smile though.
It seems to reduce their digestion, thus they cant really eat more, it just makes them sick. Maybe the signal blocks the increase productions of digestion?
Any disclosures Dr?
Very expensive.
Many side effects.
Long term side effects unknown .
When I stopped the Ozempic, I became very anxious.
I’ve used it for 2 years for my diabetes. It has done nothing for my weight. It did get my A1C down
On Saxenda I did not want alcohol at all.
And no mention of the thumbnail, what about diet pop?
Could it cause Parkinson's disease in the long term? due to strenuous production of dopamine until exhaustion of reserves in the brain nuclei???
What do you think about the “Ozempic babies” Dr Boz?
i cannot go carnivore as I love vegetables too much. My happiest meals are a big spread of Indian homecooked vegetables and dal. The idea of eating only meat makes me feel unwell. i tried fasting but it took too much headspace. I was constantly thinking about food and eating, it was really getting obsessive. But I'm in my mid fifties and getting heavier and i need a solution.
People in India have the highest rate of diabetes than anywhere else in the world. No red meat and lots of veggies
I used it 4 to yrs and had to be put on special med for bms stop taking it and started going regular again almost everyday I was taking it for diabetes didn't loose that much weight
I use zepbound. Lost 35lbs in under 5 months.
My ADHD is gone. I enjoy friendships and life.
THE FOOD NOISE IS GONE. ZERO. I have my life back. I don't care if I have to take this forever and take out a loan to use it! I clearly have a brain imbalance that needs bolstering. I feel normal now.
I enjoy small amounts of all types of food now. If I have to take this forever, fine. I suffer without it, even on keto. The food noise is insanity.
Ozempic makes sticking to a low carb / high protein (keto, carnivore) diet much easier.
I have been on a very low carb diet for 2 years - I feel great, never drink, never crave sugars and love all the bacon!
What does it do to someone struggling with ADD? I’m not really ADHD but I get a little crazy now and then but concentration is a real problem and motivation to do anything I really don’t want to do. I tried keto and lost 40 kgs but have fallen off the wagon and put it all back on plus a bit. Anyone got any experience?
Day 10 back on keto!
Depression! Dark thoughts
A big red flag is that Ozempic is not approved for sale in Europe even though it is made by the most profitable company in Europe. Our FDA is easily bribed.
Where have we seen that before?
Another crazy conspiracy.....🇺🇲
This is 100% false. Ozempic has been approved in the EU since 2018
However SOME countries in the EU have temporarily banned Oz for weight loss reasons, due to the shortage.
My buddy's been on ozempic for her diabetes ~ a year. She's lost 60 pounds and is now too slim, I think. She's a fabulous cook, but doesn't even feel like being in the kitchen. The real difference is, she's stopped drinking. I'm on a ketovore, very low carb diet and have lost 25 pounds in 10 weeks. I've stopped drinking also. It appears to me that by dropping carbs, over a very short time the unhealthy habits fall away.
I've been taken Ozympic for diabetes for 3 years and lost 5 pounds. Crude😬😬
It will probably throw me into mania...I'll see...ibuprofen does...ikr...
Dr.Boz, I am keto on and off for a few years. My wife keeps insisting to eat fruit and forget about being in Ketosis all the time. Like yourself. She told me it will mess with my hormones. Have you tested your hormones? Can you talk show there is no impact. I want to show my wife she has no idea what she is talking about.
Hi Dr Boz , it's the first time I heard you say quote ("seems their brain is hijacked to do the wrong things") unquote now what is the best way to undo this hijacking of the brain? Thank you from Johannesburg South Africa 🇿🇦🌹
Mushrooms 🍄
One place = Food
Sugar acts like alcohol
And no one is talking about concentrated glutamate or msg. B6 is needed to convert glutamate to GABA. I've noticed the RDA for B6 increase the last few years. Max recommended was 100 mg, now its 200mg. Id like to know how many mg of B6 does it take to convert 1 mg of glutamate to 1 mg of GABA. And then how much glutamate is in the concentrated version msg. How much is in a Chik-fil-a sandwich?? Super addictive. What are the effects of a B6 deficiency?
MSG also clogs up the liver. Its the hfcs of glutamate and should be banned, in all its names.
Theres food, whole food.
Then there's food drugs. Get off the food drugs.
And research rat park. Its what she's talking about.
Excellent video. She restores my faith in doctors, some doctors.
Modern food production contains endocrine disruptors. Hormonal balance matters. Just soy alone is unhealthy and its various foods. No surprise people feel less healthy.
Gila Monster venom injection. Lizards don't need much water
Just like Wellbutrin.
It’s kind of funny to compare carbs to cocaine but after thinking about it they’re similar in a lot of ways.
They are promoting here in NZ as a cure-all, but it's only available for type 2s diabetes. Go figure.
Keto diets and carnivore diets are top talk here due to chronic obesity in Polynesians, so they're trying to push for it to be over the counter.
Had to watch it twice, then waited until my brain woke up. Got it. Will the ice cream work the same way or can a titrate schedule be designed? So many questions 😂
The Keto diet is perfect for O blood types and not so much for the others. O blood type is the Hunter Gathers!
This medicine nearly killed me
Oh, no. What happened to you?
Dr. Booze
If endorphins are the issue, why can't one just supplement with endorphins?
No me vas a convencer, qué manía todos los influencers en contra de lo único que realmente funciona.
Stick to diet changes
Meds are never good newd
Do an N=1 and see if it works for you
No es la unica cosa que funciona
when i lost my mind and realized all of the truth in the world added up to one big lie i began to drink. alcohol would make me feel high but it wouldn't make it go away. if there existed a drug that could give me a decade of amnesia I'd buy it. "the world is so mercifully free from the ravages of intelligence" " ignorance is bliss "
Ketamine
My cousin is on it an is having crazy anger outbursts! She says it's not it but she is so different on this stuff. You can do it. Start with self control.
She is pushing ozempic 😢😢😢😢
My physician mentioned Wegovy. I thought of my family history of colorectal cancer and how GLP-1 meds slows down gastric emptying. The answer after a few weeks of thinking about it, and a potential hit to my budget is a definite no. Quick fixes short term up front are appealing, however, there is too much uncertainty on the backend of this drug.
After the lies and disaster of the pharmaceutical “jabs”. Of the last few years why on earth would anyone take their toxic garbage? I don’t get it. People always looking for an easy way out of situations that they put themselves in. Where’s the self respect and discipline?
Gawd you're cute.
I've lost almost 70 lbs. on this medication. It's an absolute miracle! I was pre-diabetic, I have a history of stroke and heart attacks in my family, and I was a chronic dieter with no success. I'm 51 and premenopausal. There is no way I could have gotten these results taking supplements or just exercising. I do not think about food. It's goes beyond appetite suppression. I no longer obsess about food, and I eat when I'm hungry, just much smaller amounts. Eliminating food groups, like carbs, is not sustainable and sets people up to binge. Keto is not sustainable long-term. My relationship with food is completely different, and that is what has changed.
I'd like to know how your doing after stopping it? As that's where the problem starts the craving more an bigger.
@@cherriethomas9538 I am not on maintenance yet as I have 10 -15 more pounds I'd like to lose. I will not stop taking it, I will just not take it as often. For someone that has struggled most of my life with a food addiction, this has been an absolute game changer. I eat whatever I want, just very small amounts. I do not drink or even crave alcohol. I also just don't have any of the carb cravings like I use to, so I'm not tempted to eat sweets or things like French fries. If I do feel like having something more decadent, I'm good with a bite or two, I do not feel the urge to eat the entire thing. It's truly changed my life and I feel great.
She is lecturing as if she’s talking to a medical class using some termanology that I have no clue what she’s talking about, then at the very end comparing Ozempic to Atofagy.?
for serious data people
just google the terms you dont get
Keep listening
Learn
Watch other ppl too
Keep watching them too
Learn
Autophagy is what happens when u water fast - body cleans itself up during this time. It’s very powerful for healing.
This is not a rocket science- everything simply explained.
You don’t have to be a doctor to understand this
I would find the videos tedious and boring if she re-explained concepts she's explained in many other videos. Luckily we can educate ourselves with the hundreds of other free videos she has posted.
You could just eat mainstream science nutrition
Doc , neurology isn't you strong spot
HOW DO SCIENTISTS LEGALLY GET COCAINE???
No one really understands the biochemistry behind it.
the dopaminergic hypothesis in relation to pleasure would appear to be dubious at best. why then repeat it when the characterization remains in question? I don't get it.
I dumped mine into a body of water.
😂 😂