Are PUFAs Toxic?

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  • Опубликовано: 13 апр 2021
  • Stephen Hazel asks on RUclips: "I thought we were supposed to stay the heck away from omega6 (and to a lesser extent omega3s) as they break down into toxins if you have any excess..."
    Disclaimer: I have a PhD in Nutritional Sciences but am not a medical doctor. None of this is medical advice.
    Condensed answer (see video for details): Yes, PUFA beyond what we need can be broken down into toxic byproducts, but minimizing this isn't just about PUFA restriction, but also about antioxidant nutrients such as vitamin E, vitamin C, riboflavin as FADH2, niacin as NADPH, glucose, the everything that supports the pentose phosphate pathway, manganese, magnesium, zinc, copper, iron seleneium, protein, glycine, magnesium, and all the B vitamins and other nutrients (copper, iron, and sulfur for example) that support ATP synthesis. What we need should be defined as the minimal target plus what we need to avoid deficiencies of other nutrients, plus anything needed to resolve deficiency signs and symptoms. So, the big picture is that we don't want excess PUFA, but PUFA restriction shouldn't come at the expense of any of the other components involved in their protection.
    Some relevant links I mentioned:
    www.westonaprice.org/health-t...
    chrismasterjohnphd.com/mwmpro...
    chrismasterjohnphd.com/podcas...
    • Vegetable Oils and Hea...
    And don't forget the Cliff Notes!
    chris-masterjohn-phd.myshopif...

Комментарии • 75

  • @TumbleSensei
    @TumbleSensei 3 года назад +43

    Please one day have Ray Peat on so we can get a great synthesis of his hormonal knowledge and your top notch nutritional information. 😍🙏🙏🙏

    • @petrichor100
      @petrichor100 Год назад

      i second this

    • @alanwakeup3344
      @alanwakeup3344 Год назад +4

      @@petrichor100 too late

    • @petrichor100
      @petrichor100 Год назад +2

      @@alanwakeup3344 yeah may he rest in peace! I'd still appreciate an engagement with his ideas though

  • @eddyyammine9136
    @eddyyammine9136 3 года назад +27

    Are pufas toxic?
    Short answer: yes
    Long answer: very toxic

  • @SteveHazel
    @SteveHazel 3 года назад +11

    well dang that was nice of ya! thanks very much for a full video reply, sir :) I am no nutritionist/organic chemistry guy. just a computer programmer getting old (turnin 56) and paying attention to nutrition finally. first I avoided sugar. didn't do much, but i still avoid it. then i avoided carbs. that helped a great deal. i still eat them pretty often now that I've lost weight (165 lb). then i heard Paul Saladino, MD talkin about linoleic acid and omega6 in general. This wasn't his original idea, but he thinks omega6 burning in the mitochondria of fat cells don't generate nearly the reactive oxygen species that saturated fat does. This is a signal to the fat cell to keep listening to insulin beyond what is necessary. This makes the fat cells grow and proliferate beyond what is necessary and also to send signals to all other cells in the body to stay sensitive to insulin beyond what is necessary. causing you to just get fat and not be sensitive to insulin. sugar is in everything. omega6 (seed oils) are in everything too. Mayo. Salad dressing, nuts, and anything processed, really. And since any unsaturated fat can be pretty easily broken down by oxygen, the resulting molecules are involved in many problems in the body. Ok. Too long. But I do follow you that you need some. And you don't want to give up other nutrition to stay away from them. It just seems to me that they're in meat and fish in good quantity. I'll stick with that and liver once or twice a week. Have mostly beef/lamb as they're ruminants that don't build up omega6 in their own fat like pigs, chicken. And have vegis to fill it out. and the occasional carb. Hoo. That got long. My apologies :) But thanks !

    • @relaxgood512
      @relaxgood512 3 года назад

      Paul Saladino LoL 😂 😂 😂

    • @SteveHazel
      @SteveHazel 3 года назад +1

      @@relaxgood512 his logic seems pretty sound to me. no whole food has more vitamins and minerals than offal meats like liver, heart, kidney. what do you find lol about the things he talks about?

    • @relaxgood512
      @relaxgood512 3 года назад

      @@SteveHazel everyone is entitled to believe in data free information.

  • @nadernayo
    @nadernayo 3 года назад +3

    Amazing review of PUFA's thanks... so impressive how you memorize all the metabolic pathways..

  • @jeremiahmcpadden4386
    @jeremiahmcpadden4386 3 года назад +16

    I eat 4 egg yolks a day, with liver 1-2 a week. I also eat almonds-mostly for riboflavin.
    Best advice is to just cut out fast food and stick with Whole Foods.

    • @markaguilera493
      @markaguilera493 3 года назад

      Hi, how long have you been eating 4 eggs a day? Is that amount of pufas tolerable?

    • @jeremiahmcpadden4386
      @jeremiahmcpadden4386 3 года назад +2

      ​@@markaguilera493 So for context: I do skip a day maybe once a week, I use pasture-raised (grass fed) eggs so there's more vitamin E and more DHA, and I also do powerlifting.
      I eat 4 eggs for other reasons as well: choline, selenium, protein, etc. etc. I've not noticed any new inflammatory problems occur since starting, and I've seen a reduction in inflammatory problems (psoriasis) since beginning this habit some 4-6 months ago.

    • @markaguilera493
      @markaguilera493 3 года назад +1

      @@jeremiahmcpadden4386 Right, so presumably all the good things in the eggs outweigh the potential harm of the arachidonic acid? Thanks for the answer.

    • @jeremiahmcpadden4386
      @jeremiahmcpadden4386 3 года назад

      @@markaguilera493 I would presume so. Same thing with liver as well.

    • @Bigax99
      @Bigax99 3 года назад +2

      Ive been on 7-8 whole eggs a day for about 4 years now ( pasture-raised grass fed) . Im 39 and do weight training 4-5 days a week. I have not noticed any negative effects. My Doctor told me my blood work was really good as well. Only issue with blood work was high creatine levels, but I do take 5 grams on creatine monohydrate a day.

  • @thehylander266
    @thehylander266 3 года назад +11

    The way I look at it is, most of the foods that are high in PUFA but also other nutrients can easily be replaced by other foods that are equal or higher in those nutrients but lower in PUFA. So that’s who I structure my diet. If I can get away with eating foods that give more nutrition for less total PUFA, then I think that works best for me.
    So for example, why eat almonds when I can eat macadamia nuts. Or why eat a ton of egg yolks for biotin when I can eat chicken liver which is far higher in biotin (and other nutrients) and has less PUFA.
    With the exception of lower PUFA nuts like macadamia, I don’t eat nuts because other foods can give me the same or better nutrition profile for less PUFA. I mean, if I want magnesium, I’ll easily get a ton of them with dark chocolate and tropical fruits and strong dark coffee. And with chicken and veal liver I eat every day (just enough for my Vitamin A and bitcoin needs, so I don’t overdo the Vitamin A), in conjunction with lean red meat and cod, I get more than enough choline and omega 3’s without going overboard.
    I honestly can’t think of a single high PUFA food that is so nutrient dense that I can’t trace with a lower PUFA food that has equal or more of those nutrients.

    • @nynzxoxo
      @nynzxoxo 2 года назад +2

      Could you tell us what meals/foods you eat most for balanced nutrition?

    • @KevinZJR
      @KevinZJR Год назад

      What do you think of (natural) cod liver oil? Does the vitamin A in it outweight its PUFA disadvantage?

  • @pabloqueiroz7230
    @pabloqueiroz7230 4 месяца назад +1

    For one year, I followed the Ray Peat scheme religiously, which antagonizes PUFA and supports thyroid. I also adhered to the teachings of Danny Roddy and Haidut (from the Ray Peat Forum). After 01 year I developed Sjögren Syndrome, hyperthyroidism, hair thinning, oily skin, seborrheic dermatitis, stable angina, dysphoric mood, migraines, periodontal disease and kidney stones. The advantages that I noted were good sleep, good energy levels and good libido.
    After reintroduction of normal doses of omega-3 and omega-6, all conditions rapidly resolved, except for hair thinning, seborrheic dermatitis, periodontal disease and angina. Energy levels and libido didn't deteriorated after PUFA and are still satisfactory.
    I don't know if there is a causal link between the conditions I developed while following the Ray Peat scheme and PUFA restriction. But the reintroduction coincided with the clearance of the ailments...

    • @JasonOwensYT
      @JasonOwensYT 4 месяца назад +2

      Omega 3s are not PUFAs. You can be high OM3 and low PUFA. I see you leaving this comment everywhere. So hopefully you read this. Im glad you fixed your problem.

    • @pabloqueiroz7230
      @pabloqueiroz7230 4 месяца назад

      @@JasonOwensYT 😂😂😂

  • @KKing55
    @KKing55 3 года назад +2

    I Owe You so Much~! You have helped me to understand how to feel better where No other Dr ever could. Thank You for the bottom of my Heart~! 💙💞💙💞

  • @Michael-ei3vy
    @Michael-ei3vy 3 года назад +11

    Have ray peat on!

    • @wellnesspathforme6236
      @wellnesspathforme6236 3 года назад +4

      Where is Ray Peat's research that shows all-cause mortality is reduced by avoiding the 1% highest quality Omega 3's that were used to help Dara Torres win silver in the Olympics as a 41-year old mother (missed gold by 1/100th of a second), used to help Randall McCloy miraculously recover from multiple organ failure as the lone Sago mine disaster survivor, and used to help power Dean Karnazes to avoid inflammatory injuries as he's doing his ultra-ultra running events?
      I have to ask -- what is the highest level athlete applying Peat's principles?
      Dr. Barry Sears is nonpareil in producing anti-inflammatory athletes, as in the best ever to exist across multiple sports, and the highest quality fish oil is a pillar in his program.
      This has to be explained by Peat, not ignored.
      Also, iron overload and bio-copper depletion play key roles that tend to get lost in Peat's PUFA claims. Sewer of the sea oils and almost all seed oils are toxic -- that's a given, and NOT what Dr. Barry Sears and I am talking about.
      Note -- of course, the omega-3's and 6's are best balanced, as taught by Dr. Sears. One does best to achieve a 1.5 AA/EPA ratio. (AA -- arachidonic acid; EPA -- eicosapentaenoic acid).

    • @wellnesspathforme6236
      @wellnesspathforme6236 3 года назад +1

      @@moneymanusa7 Detoxing iron and renutrifying magnesium, retinol (plus sun exposure = retinoic acid), and organic copper are a prime objective. I was born pretty toxic as evidenced by my poor energy production in my youth. I've had a fair amount of stress 8n my life, too, which depletes magnesium and bio-copper. 8n addition, I took zinc supplements for too long and depleted my copper before I knew about its importance.
      I eat a variety of organic veggies, I eat organic grassfed/finished liver (both lamb and beef),
      lamb heart (tasty!), sardines, minimally processed organic whole cream, berries, organic pSteured eggs, sprouted organic bread free of iron filings, and occasional organic hot cereals with cream and a minimal amount of organic maple syrup. I eat raw organic carrots and celery. I eat various nuts and butters. I supplement with refrigerated IFOS 5-Star fish oil, but do believe it is a hack that minimizes iron related inflammation (fix the iron issue and food should be fine). I also supplement with Udo's Oil that I keep vacuum sealed and refrigerated inside its box. I also supplement with bee pollen, kelp, and magnesium supplements.. I only use Morton's Canning and Pickling Salt based on Dr. Hal Huggins clinical results and the principlenthat inorganic minerals are toxic (organic minerals being the goal).. I am a recovering dairy addict (blood-tyoe B), so I do drink minimally processed organic milk from time to time, Sometimes, I buy raw milk and cream, but they are expensive. I lightly fry with clarified butter or ani.al fats. I use my glass coffee pot to make organic soups and to somewhat cook some veggies while eliminating the cooking pot heavy metals and/or coating toxins. I eat gouda cheese for the K2 value. I really like hot Yerba mate and green tea with lots of whole cream and maple syrup, but I'm taking a hiatus for now. I will add a little honey from time to time, too. I used to eat a lot of organic hamburger, but I'm transition to more organic chicken to minimize dietary iron and force my body to pull from its iron stores.
      I want to start making broccoli sprouts to juice again. I'm ramping my rice bran supplementation as well. I also eat apples and oranges, and I try to follow Zone Diet micronutrients principles to keep insulin and glucagon in their therapeutic zone.

  • @aj-pf5yt
    @aj-pf5yt 2 года назад +1

    Chris, in exploring how the establishment made war on cholesterol, unscientifically , we could add that this is when they thrust puffas, in the way of vegetable oils on the population.

  • @wellnesspathforme6236
    @wellnesspathforme6236 3 года назад +1

    Dr. Carolyn Dean has stated that taking magnesium with fat blocks/limits magnesium supplement absorption. Is this animal fat only? Does it take include fats in seeds?
    What are your thoughts on this given the criticality of absorbing magnesium in our magnesium deficient world?
    I also understand it is best to take magnesium supplements away from significant calcium ingestion.

  • @David-kd5mf
    @David-kd5mf 3 года назад

    Can you explain if pufa in corn is neutralized in nixtamalization process? Also isn't vitamin e content in fresh ground wheat flour high but gone within 24 hours?

  • @jeromedebeaurivage389
    @jeromedebeaurivage389 Год назад

    really interesting

  • @saneb5955
    @saneb5955 2 года назад +1

    Almost every food source has some pufa in it. I think the ultimate point here is to limit the amount of pufa. Meaning foods that are extremely high in pufa that don’t have enough nutrients in it to be worth consuming. An example is oysters. 2 servings a week of oysters can supply you with an entire weeks worth of minerals and some important vitamins/hormones. It also is high in pufa, particularly omega 3. Most anti-pufa advocates say to consume oysters, including ray peat twice a week. I think the message is good, and there is just bad communication between everybody when it comes down to the core concept. It almost appears that everyone agrees with one another but are looking at it from a different angle. Almost like drawing the number 6 and standing on opposite sides. One person sees a 9 the other a 6. You all agree but from a different light.

  • @irvpaton8626
    @irvpaton8626 2 года назад

    I wonder if we should "Stay the heck away from" manufactured seed oils that are in all our manufactured foods. I'm guessing there is not a lot of good reason to fill up on the junk food that gets its fat from the seed oils. I'know you are discussing this at the higher level, but the practical issues of junk food are relevant in my family, so I tend to push the issue to avoid these foods, and I got my first hints that a lot of seed oils are bad from a presentation you did a long time ago about the studies done in some institutions in Europe on the oils. (and you mentioned that at the end of this video).

  • @supimsatan
    @supimsatan 3 года назад

    Question: I eat canned cod liver once per week (About 75 grams of liver). It contains 7500 MCG Vit A + 5,4 grams omega 3. I know to much vitamin A from Animals can be harmfull. Can i eat it all at once or should i spread it across the week?
    Thanks!

  • @igaluitchannel6644
    @igaluitchannel6644 2 года назад +1

    We already get PUFAS even if we try very hard to minimize them.

  • @joshux3210
    @joshux3210 2 года назад

    What iabout avoiding pufa and take higher dose of essential nutrient supplements?

  • @josephinemiller68
    @josephinemiller68 3 года назад

    Hello, I know this is a bit off topic but why are Supplement companies adding vitamin a to K2 and D3 combinations?
    Should I take them all three separately or together? Why the vitamin a? I know about the K2 and D3 benefits with calcium transport.

  • @aj-pf5yt
    @aj-pf5yt 2 года назад

    As you optimize the metabolic rate.......cholesterol is lowered, as a fast metabolism will convert more cholesterol to progesterone and pregnenalone and all other hormones.

  • @jameskantor0459
    @jameskantor0459 3 года назад +1

    @Master John, I thought polyunsaturated Omega 3 are in fish and thus healthy. Please explain. I do rake fish oil, what am I looking for in fish oil.

    • @eddyyammine9136
      @eddyyammine9136 3 года назад +4

      Yes stay away from fish oil suppliments

    • @rbaddict2947
      @rbaddict2947 3 года назад +2

      Fish oil is horrible for you. You only need a tiny bit of DHA which you can get by eating fish once a mont

  • @carnifex8
    @carnifex8 2 года назад

    Ok, i suppose ill have to quit using pumpkin seed oil. Any ideas if i already did alot of damage? Used it for about 2-3months 1 tablespoon/day. Also took fish oil for quite some time, doctor told me to do so... To "boost" immunity. It's weird when doctors tell you that all these oils are very good but then u realise u were taking toxins.. Well hopefully a few months of those didn't do permanent damage.

  • @kellyclover5953
    @kellyclover5953 3 года назад

    I eat walnuts all the time. They are mostly fat and especially polyunsaturated fats. That raises the question of whether I should be wary of eating walnuts.

    • @StriderGTS
      @StriderGTS 3 года назад

      Walnuts have one of the best omega 6/3 ratios. Low in 6 and higher in 3. Peanuts are one of the worst, 5000-1 omega ratio.
      We need to be minimizing omega 6.

  • @nameremoved4010
    @nameremoved4010 3 года назад

    I avoid refined PUFAs. I get PUFAs from mostly unroasted or freshly home roasted nuts and seeds. I cook meat and eggs using coconuts fat. I do use warm butter and olive oil on salads. I eat too much canned fish but it is better than some alternatives.

  • @ElieZ
    @ElieZ 3 года назад +2

    5:17 missed a good pun there pal.

  • @RBimas37
    @RBimas37 3 года назад

    Is there a way to accelerate the process of getting PUFA's out of one's body??

    • @LulaJake
      @LulaJake 2 года назад

      Yes but don't. I took an aggressive path to the keto diet and made myself ill from the amount of toxic pufa my body was processing. It took us many years to accumulate this body fat, it will take a few more to get rid of it.

    • @RBimas37
      @RBimas37 2 года назад

      @@LulaJake Speak for your self. It took 2 months. 1 sugar only - 3 weeks of water fast and 1 week of dryfast.

    • @LulaJake
      @LulaJake 2 года назад

      @@RBimas37 a week without water? lol

    • @RBimas37
      @RBimas37 2 года назад

      @@LulaJake Yes

  • @bob-ss4wx
    @bob-ss4wx 3 года назад +2

    Great information and way too long

  • @demilov7791
    @demilov7791 Год назад

    How do you cook for a whole family ? Different ages and gender. I guess peanut butter and jelly is no longer suitable for kids lunches. I love all this info but we need a practical approach for homemakers… they have the power to educate and can make a difference in American health and prosperity.❤

    • @evelynda5235
      @evelynda5235 6 месяцев назад

      Cook with simple flavors for everyone. I just make my kids what I eat. If I am making something more fancy i make a version without sauce or sauce on the side just in case.

  • @AceKinG2024
    @AceKinG2024 3 года назад +1

    Unfortunately chris got into a car accident. Dont know his actual health status

  • @williehasenbos4899
    @williehasenbos4899 3 года назад

    don't the plants produce these as a defence ? ...against being eaten ?!!!

    • @jeremiahmcpadden4386
      @jeremiahmcpadden4386 3 года назад +1

      Maybe as a mechanism for repair but not to ward off bugs? I’m no botanist, I just don’t see how pufa would be related to plant defense.

    • @GoetzimRegen
      @GoetzimRegen 3 года назад

      Antifreezing agent

  • @user-er9vp1mf1z
    @user-er9vp1mf1z 3 года назад +4

    Save your hair!!

  • @forest989
    @forest989 2 года назад

    Eat beef, lamb and occasionally seafood. Limit or avoid nuts due to high linoleic acid. Take a multivitamin to get adequate vitamins and minerals.

  • @aj-pf5yt
    @aj-pf5yt 2 года назад

    If you slow your metabolism with puffas.....you will be loosing your magnesium. Far better to optimize your metabolic rate, good metabolic rate will maintain magnesium in cell function.

  • @strategyknight4820
    @strategyknight4820 3 года назад +2

    Not sure if he has touch on it but I think a video talking about zoochemicals would be interesting.