Countercurrent multiplication in the kidney | Renal system physiology | NCLEX-RN | Khan Academy

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  • Опубликовано: 8 апр 2014
  • Created by Raja Narayan.
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Комментарии • 246

  • @brandiigiibson
    @brandiigiibson 7 лет назад +290

    I do have to admit, I love your videos, but this needed to focus more on the counter-current. the balance.

  • @bandsux012
    @bandsux012 6 лет назад +6

    Med school student here who wanted to clarify some past comments. This is a solid, basic video to understand countercurrent MULTIPLICATION w/ your typical cortical nephron. Most of the negative comments coming from people who were probably looking for an explanation about countercurrent EXCHANGE which is a DIFFERENT passive process dealing with the vasa recta and juxtamedullary nephrons

    • @user-qw2qb7rk2m
      @user-qw2qb7rk2m 5 месяцев назад +1

      super late here, but bless this is the most helpful comment I've read in my history of RUclips

  • @mfl639
    @mfl639 9 лет назад +43

    It may sound corny but you also have a very pleasant voice as well as tone. So it makes it even better to listen to your very precise and well presented videos.
    thank you

    • @dianalozada8959
      @dianalozada8959 11 месяцев назад

      Does he not sound like Justin Long?!

  • @pierredeuj3593
    @pierredeuj3593 7 лет назад +42

    i have eargasm listening to this silky smooth voice

  • @vbuksa
    @vbuksa 9 лет назад +10

    i just want to say thank you, i had such a hard time in my anatomy class understanding the physiology of the nephron loop, you explained it well! thanks again

  • @kaykaysparents
    @kaykaysparents 10 лет назад +6

    i just spent the past couple hours watching all of the excretory/urinary system videos. so clear and detailed. just wanted to say thank you!! they are very helpful and just gave me such a more clear understanding of this system!! :)

  • @nicoleteufel6118
    @nicoleteufel6118 10 лет назад +2

    You're incredible- thank you! remembering the names is the hardest part, the repetition and explanation of why things get their names e.g. proximal convoluted tubule is so helpful! Thanks!!

  • @hwyable
    @hwyable 7 лет назад +444

    theres no actual explanation on countercurrent mechanism here at all......

    • @Goshujinsama01
      @Goshujinsama01 7 лет назад +35

      thank you for saving me some time

    • @jacobgarwin5616
      @jacobgarwin5616 7 лет назад +83

      the descending and ascending loops have different permeability. The ascending allows for solutes to move out into the the medulla space which, in turn pulls (through osmotic pressure) water from the descending tubule. This causes the filtrate to become more concentrated as is moves down the loop and less concentrated as it moves back up. This is all happening while the filtrate is moving so it has a multiplying effect. Hope this explains somewhat.

    • @venok8863
      @venok8863 7 лет назад +4

      sure was waiting for something like that.... thank you

    • @thejoelster5635
      @thejoelster5635 6 лет назад +2

      why does the concentration of filtrate decrease as it moves up the ascending limb of the loop of henle though?

    • @ArcLiew
      @ArcLiew 6 лет назад +16

      Joel V George, the concentration of the solute decreases as it moves up the ascending limb because solutes such as Na, Cl, K, are removed from the fltrate via active transport

  • @brittneymowrer8190
    @brittneymowrer8190 7 лет назад +1

    I've watched several of your videos and I am so impressed. I'm thankful for the simple explanations of what can be complex subjects. Fantastic teacher!

  • @Canishii
    @Canishii 9 лет назад +88

    I'm so attracted to your hand writing

    • @ccmmoopp45
      @ccmmoopp45 7 лет назад +9

      you should call it click writing

  • @stacyduncanson8966
    @stacyduncanson8966 10 лет назад +11

    Of all Khan's video lectures ... This guys are the very best!! To the guy who facilitated this video, Thanks for being so awesome at teaching.

  • @YukiOnnaNura
    @YukiOnnaNura 6 лет назад +11

    The title is a misconception. I was waiting for the countercurrent mechanism explanation

  • @Bettadenyou1
    @Bettadenyou1 8 лет назад +2

    This was an absolutely beautiful video. I have scoured the web looking for information about the urinary system and this was the absolute best! Thanks again.

  • @TomoMomoDomo
    @TomoMomoDomo 3 года назад +5

    TY for saving me from mild panic while I tried to make heads or tails of this thing for my exam.
    Saved me at least 5 minutes of internal sobbing

  • @soledaom8747
    @soledaom8747 4 года назад +7

    Genius, you managed to explain me what the profs at university couldn't. Big compliment for your work, I really appreciate it!

  • @wendyjones2332
    @wendyjones2332 10 лет назад +3

    One of the most helpful science videos that I've watched! My teacher will be asking about countercurrent multiplication today - now I'll be ready.

  • @keishlarodz6021
    @keishlarodz6021 6 лет назад +4

    The juxtaglomerular apparatus ( Macula densa) forms when the " thick portion of the ascending limb of Henle" passes through the vascular pore, not the distal convoluted tubule, because the distal comes actually after the macula densa.
    This video gives a nice overview of the nephron tubules, even when it doesnt really expalins the countercurrent multiplication.

  • @nerveblock
    @nerveblock 8 лет назад +39

    really need to include the vasa recta, which is where the actual "multiplication" comes from.

  • @bigdaddylee8019
    @bigdaddylee8019 8 лет назад +1

    only the best works at khan's academy. i have so much respect for mr khan for hiring only the very best.

  • @aniketmukhopadhyay8962
    @aniketmukhopadhyay8962 3 года назад +6

    I was having a hard time trying to understand the counter-current mechanism, but this video made it crystal clear. Thanks a lot!

  • @aMeRiCaNiDoLrOcKz997
    @aMeRiCaNiDoLrOcKz997 9 лет назад

    Thank you so much! I initially got confused with what you mean by reasorbed. Either you talk about being reasorbed by the tubules or the body. But, I get it now. So thank you so much!

  • @dennisy2599
    @dennisy2599 8 лет назад +1

    THIS WAS BEAUTIFULLY EXPLAINED. THANK YOU!!!!

  • @SlimTribe
    @SlimTribe 9 лет назад +24

    Taught this better than my teacher

    • @locomojoboy2
      @locomojoboy2 8 лет назад

      +Anchor BRO OR....he's just a bad teacher who isnt very good at teaching lesson so that it's easily understood *sigh*

    • @yarenot9878
      @yarenot9878 8 лет назад

      +SlimTribe Tell me about it. My teacher basically ends up confusing us more....tsk tsk.

  • @a1sauce81
    @a1sauce81 5 лет назад +1

    This is very well explained. Best I’ve seen on RUclips. By the way I teach A&P so I know what I’m talking about

  • @sonav5367
    @sonav5367 8 лет назад +1

    Thank you so much! You made learning for my test so much easy! :)

  • @TheHappyTears
    @TheHappyTears 8 лет назад +7

    My comparativ anatomy exam is tommorrow, and thanks to this video I finally get the freaking nephron! Yay, thank you!

  • @tonyaoesterling9673
    @tonyaoesterling9673 10 лет назад

    This helped more than any other video's i've found. THANKYOU :D

  • @LFindable
    @LFindable 9 лет назад

    subscribed: checked! So glad I found your channel, your explanations are extremely helpful and detailed!

  • @JeanClaudeKresse
    @JeanClaudeKresse 8 лет назад +1

    This is such a good video, thank you very much. I could listen to you all day bro.

  • @anomalyp8584
    @anomalyp8584 7 лет назад +4

    If only I had seen this earlier.... It's really well explained!!

  • @yarenot9878
    @yarenot9878 8 лет назад +2

    Thanks so much for helping me study for my bio IB exam!

  • @matuckyazpe828
    @matuckyazpe828 9 лет назад

    Thank you so much!!! your videos really help me to understand all concepts
    your explanation is amazing

  • @MsSusanGager
    @MsSusanGager 9 лет назад

    This is a great breakdown of how this works, thank you!

  • @khaledt6203
    @khaledt6203 9 лет назад +1

    great explanation, really like it, thanks a lot!

  • @shayanazimi899
    @shayanazimi899 10 лет назад

    That was the best explanation I found on youtube so far!!

  • @mandyads
    @mandyads 8 лет назад +3

    The only advice I would give on this video is to add the significant hormones that cause reabsorption in different parts of the nephron. That way, students can pull in the endocrine system and get a better understanding of how the renal, endocrine and cardiovascular system all connect. That would be more of MCAT style thinking... But great video.

    • @lizpiper6
      @lizpiper6 8 лет назад

      +Amanda Strong Yes, completely agree! Hormones are so heavily involved in maintaining homeostasis. Would be beneficial to hear about renin, aldosterone, etc.

  • @SG333_
    @SG333_ 2 года назад

    Such a fantastic and well explained video! THANK YOU!!!

  • @asmitameshram5537
    @asmitameshram5537 10 лет назад +1

    This video is great! Thank you so much! made it super easy to understand! ^.^

  • @Arham1716
    @Arham1716 9 месяцев назад

    I must respect Khan Academy ....They explain detailed topics In such a simple manner and I thought tht these Topics were too Hard to grasp it😢..I would donate to khan academy

  • @venok8863
    @venok8863 7 лет назад +1

    thank you very much Khan Academy..... what is being explained here is just what our lecturer teaches us, I am starting to think that maybe our lecturer watches your videos before they come to teach us.

  • @kissesfrme
    @kissesfrme 10 лет назад

    You're great!!!! Thanks for sharing your knowledge!!!!

  • @shivanichhabra1166
    @shivanichhabra1166 Год назад

    this video is so impressive. my friend's father is suffering from kidney failure. He also took dialysis. I told him about Dr. Vikram Chauhan. He took treatment from DR. Vikram now his health is much better.

  • @sydneysoleil837
    @sydneysoleil837 10 лет назад +1

    Such a great video with what I need to know for my final. Thank you!

  • @mano7591
    @mano7591 5 лет назад +5

    Wow these videos are well explained and are super clear!! Thank you KHAN ACADEMY 🙏💕

  • @poulamichakraborty1163
    @poulamichakraborty1163 6 лет назад

    Amazing and very well explained videos .
    Extremely helpfull for students

  • @parinithamaben4141
    @parinithamaben4141 9 лет назад +1

    Great explanation! It really helped! Thanks Khan Academy ..

  • @brenyboy26
    @brenyboy26 9 лет назад

    fantastic video, great programme and so interactive. Brilliant teaching method and delivery with your speech. HD.
    Thank you!!

  • @khalkhan3548
    @khalkhan3548 9 лет назад +2

    I can't even tell you how much your video's have helped me. Thank you, thank you, thank you. :'(

  • @cherry.25
    @cherry.25 9 лет назад

    I finally understand all of it! Thank you!

  • @TadanoCandy
    @TadanoCandy 10 лет назад +1

    Your handwriting is beautiful :)
    Thank you for your videos as well :P

  • @jasryanbirk8102
    @jasryanbirk8102 10 лет назад +1

    Good overview. My understanding of the vascular support of the nephron is different however. I understood that the afferent arteriole split into 2 vessels, the peritubular capillary and the vasa recta. The peritubular capillaries are localised to the cortex, where they take up solutes and water reabsorbed by the PCT and DCT. Most of renal plasma flow passes through these vessels. However a small proportion of the blood from the afferent arteriole is sent to the medulla in vessels known as vasa recta, in order to take up the solute and water reabsorbed by the loop of Henle. This is important as the generalized vascular support structure illustrated in the video above would quickly dilute the medullary interstitium (as the salty interstitium would draw water out of these vessels). Hence blood supply to the medulla is necessarily poor.

  • @etonefelix
    @etonefelix 6 месяцев назад

    Wow beautiful explanation. Thank You Sir.

  • @leenakhan96
    @leenakhan96 9 лет назад

    this is great thank you so much! which is the second video you mentioned which talks more about the juxtaglomerulus apparatus? i cant seem to find it :(

  • @minatachkanlouei6238
    @minatachkanlouei6238 7 лет назад

    Thank you so much, your explanation was great.

  • @avinashmurthy7657
    @avinashmurthy7657 9 лет назад

    Amazingly helpful!

  • @sanazbehnia
    @sanazbehnia 6 лет назад

    I loved this video, thank you!

  • @anuragS117
    @anuragS117 10 лет назад

    Really Helpful!! Thank You

  • @MrGovindsah
    @MrGovindsah 8 лет назад

    Excellent video, Conceptually very clear...

  • @JustYourAverageToes
    @JustYourAverageToes Год назад

    I love watching English-spoken videos with only knowing the body parts in my native language

  • @ashlengibbs8494
    @ashlengibbs8494 8 лет назад +1

    Very helpful!

  • @JackieMasso
    @JackieMasso 9 лет назад

    Thanks for that great information!!!

  • @bavithrabose2238
    @bavithrabose2238 6 лет назад

    awesome explanation sir...thank you

  • @monikajuneja1384
    @monikajuneja1384 6 лет назад

    oh god I was like trying to understand it from 2 days from my textbook but it just took 10 mins to understand all this stuff thanks a lot

  • @twothirdsostrich
    @twothirdsostrich 8 лет назад +14

    Are you Enrique Iglesias? Because you're my hero.

  • @manopriya3538
    @manopriya3538 7 лет назад

    Easy to understand the concept.good

  • @xJMT
    @xJMT 9 лет назад

    Thank you, really helps :)

  • @shantharamasharma8809
    @shantharamasharma8809 5 лет назад

    helped me a lot . thanks

  • @himangshusharma258
    @himangshusharma258 4 года назад

    Awesome man.

  • @ordinarymind1804
    @ordinarymind1804 9 лет назад

    So helpful. Thanks a lot.

  • @alikazmi5012
    @alikazmi5012 8 лет назад

    Thnk God finally I have counter current mechanism

  • @abhayanand9585
    @abhayanand9585 Год назад

    Wonderful explanation!

  • @sohrabzandi396
    @sohrabzandi396 3 года назад

    I can't never understand like this thank you sooooooooomuch really thanks

  • @DevilentAngel
    @DevilentAngel 10 лет назад

    LOL to be peed away. Thanks for this video it helped a lot!

  • @MeCassie95
    @MeCassie95 8 лет назад

    I LOVE YOU FOR THIS VIDEO!

  • @lcdp9459
    @lcdp9459 Год назад

    I absolutely adore your handwriting!
    Excellente video and thank you!! 💚

  • @msldt9675
    @msldt9675 7 лет назад

    Thank you so much for the explanation. 😁

  • @akbar_3li
    @akbar_3li 4 месяца назад

    Amazing!!!!

  • @IronEducation
    @IronEducation 4 года назад

    Khan academy coming in clutch 🙏

  • @MsLozeh
    @MsLozeh 8 лет назад

    The loop of Henle is now called the Nephron loop. at least thats what they are teaching in universities now. But this is a brilliant video I finally got my head around this system

  • @melodylin4924
    @melodylin4924 10 лет назад

    thank you. i am taking my ap bio test in 2 days. the book doesn't make sense to me but this video saved me. THANK YOU

  • @anishashoka2646
    @anishashoka2646 9 лет назад

    nice video .helped me a lot

  • @5MinuteSchool
    @5MinuteSchool 10 лет назад

    The Afferent Arterioles branch off from the Interlobular Arteries not directly from the Renal Artery

  • @vivekdalal6788
    @vivekdalal6788 9 лет назад

    Thanks a lot, really nice video...

  • @sobster123
    @sobster123 8 лет назад +26

    I want to share a scientific kiss with this man

  • @alikazmi5012
    @alikazmi5012 8 лет назад

    thanks its very useful

  • @wdeltor2
    @wdeltor2 10 лет назад

    Very good stuff man

  • @tuvu6560
    @tuvu6560 11 месяцев назад

    Thank you so much!

  • @johnnyappleseed5476
    @johnnyappleseed5476 9 лет назад +1

    WOOO NEPHRONS

  • @ferminadelson7093
    @ferminadelson7093 9 лет назад

    helps me a lot

  • @jcup8387
    @jcup8387 9 лет назад

    Great handwriting and explanation!

  • @aminamostafa100
    @aminamostafa100 9 лет назад

    Great really thanks 😄

  • @wishwish78
    @wishwish78 3 года назад

    Great jobb!!

  • @luzsennysantos233
    @luzsennysantos233 9 лет назад

    thank you sir !!

  • @k.s.hkeemoo5949
    @k.s.hkeemoo5949 4 года назад

    Fantastic ..♡

  • @HafizahHoshni
    @HafizahHoshni 8 лет назад

    thank you!

  • @parthpatel7258
    @parthpatel7258 6 лет назад

    The reabsorption arrows for Na and Cl ions are confusing in ascending limb. Besides that it's a good explanation. Thank you.

  • @kakankrakau
    @kakankrakau 8 лет назад

    Nicely done! However i read in Junquiera's Basic Histology that 65 % of the water is reabsorbed in the proximal tubule. Almost 100 % of the glucose, the vitamins, the small proteins and the aminoacids get reabsorbed. About 85 % of the ions as well.

  • @leefangi365
    @leefangi365 6 лет назад

    The thin segment of ascending limb should be facilitated diffusion while the thick segment of ascending limb carried out active transport

  • @msuzaid7103
    @msuzaid7103 9 лет назад

    good explanation skills. (y)

  • @subhanaabidatus3866
    @subhanaabidatus3866 6 лет назад

    Nicely described❤