Hormonal Therapy for Breast Cancer: We Teach You

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  • Опубликовано: 5 июл 2024
  • We teach you about hormonal therapy for breast cancer. Drugs such as tamoxifen and aromatase inhibitors are key treatment options for most breast cancers.
    VISIT THE BREAST CANCER SCHOOL FOR PATIENTS:
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    Questions for your Medical Oncologist:
    1. What type of hormonal therapy do you recommend?
    2. Will I also benefit from chemotherapy?
    3. What are the side effects of hormonal therapy?
    4. Will I need 5 or 10 years of these medications?
    5. Would the genomic assay Oncotype DX be helpful?
    6. What is Hormonal Therapy?
    Anti-estrogen (estrogen-blocking) medications, prescribed as pills, are incredibly effective at treating certain types of breast cancer. Hormonal therapy is given to about 70 to 80% of women with breast cancer. Chemotherapy, on the other hand, is a more intense cancer treatment that is generally administered intravenously. Most patients will not need chemotherapy. Many women that do need chemotherapy will also benefit from hormonal therapy. These treatment decisions are complex ones with your medical oncologist. You will make better choices when you are well informed before meeting with your medical oncologist.
    Do my “Receptors” suggest Hormonal Therapy?
    When the estrogen circulating in your blood stream interacts with a breast cancer that has “Estrogen Receptors” (ER) present on its surface, it tends to flip the ER switch to the “on” or “grow” position for ER Positive tumors. The same can be said to a lesser extent for the “Progesterone Receptor,” if your cancer is found to also be PR positive. Patients with ER+ breast cancers almost always benefit from the anti-estrogen effects of hormonal therapy. These medications can make cancer cells die, or slow down their growth. If a few cancer cells have already spread to other parts of the body, these medications are incredibly effective at preventing these cells from growing and threatening your life in the future. In other words, those who take hormonal therapy for ER+ tumors have a more successful chance at long-term survival when compared to those who do not.
    About 80% of all breast cancers are ER+. Even if your medical oncologist recommends chemotherapy for you, if your tumor is ER+ you will also benefit from up to 10 years of hormonal therapy after chemotherapy. Hormonal therapy is never given during chemotherapy nor during radiation therapy.
    What is “Tamoxifen?”
    Tamoxifen is an anti-estrogen medication (pills) that has been used with great success with ER+ cancers for three decades. It is now the primary hormonal therapy for younger, pre-menopausal women. It is also the primary drug for men with breast cancer. It is used for some post-menopausal women.
    What are “Aromatase Inhibitors?”
    Aromatase inhibitors (AIs) are a class of anti-estrogen medications (pills) that have proven to be slightly more effective than Tamoxifen for post-menopausal women. It is not recommended for younger, pre-menopausal women, except in certain circumstances. The three most common versions are Anastrozole (Arimidex), Letrozole (Femara), and Exemestane (Aromasin).
    What are the side effects of Hormonal Therapy?
    Side effects vary greatly from one person to the next for both types of hormonal medications. Some have no symptoms at all. Most have very tolerable side effects. Some patients will need to change hormonal therapy medications to find the best balance of cancer benefit versus side effects. Several side effects that are rather common for both tamoxifen and aromatase inhibitors are hot flashes, night sweats, joint pain, and vaginal dryness. Below, we list some of the other specific side effects for both drugs.
    Tamoxifen Side Effects:
    Increased risk of uterine (endometrial) cancer
    Increased risk of developing blood clots
    Slows normal bone loss in most women (a “good” side effect)
    Cannot be taken during pregnancy because of risk of birth defects or fetal death
    Can temporarily induce menopause in pre-menopausal women.
    Aromatase Inhibitor Side Effects:
    Can worsen bone loss (osteoporosis) in women
    Muscle and joint aches and pains
    Would an “Oncotype DX” assay help me?
    Patients who have a small, estrogen receptor positive, HER2 receptor negative tumor, and no evidence of cancer in their lymph nodes may benefit from an Oncotype DX genomic assay. This cutting-edge test looks deeper into your cancer cells to better identify people who may also benefit from chemotherapy with ER+ breast cancers. The decision to undergo chemotherapy, in addition to hormonal therapy, is a complicated one. Your medical oncologist uses many factors to help decide if you will benefit from chemotherapy. An Oncotype DX analysis of a portion of your breast cancer tissue can be instrumental in this decision.

Комментарии • 270

  • @sheebasebastian5874
    @sheebasebastian5874 4 года назад +152

    I dream for a complete cure for all type of Cancer . Prayers

    • @jennyaquino699
      @jennyaquino699 2 года назад +2

      Amen

    • @jennyaquino699
      @jennyaquino699 2 года назад +5

      Gumaling lahat ng may cancer in jesus name.amen

    • @mibrahim7212
      @mibrahim7212 2 года назад +1

      Ameen

    • @johnlees3696
      @johnlees3696 2 года назад

      Professor Thomas Seyfried look him up all Cancers are fermenters cut the food supply they all died All. Scientific papers ect. No Chemo .No Radiation no ongoing tablets. No wonder they don't want to know.

    • @anumandhanaayagan
      @anumandhanaayagan 2 года назад +3

      i too pray for the same

  • @pretreacheprice4567
    @pretreacheprice4567 2 года назад +20

    Thank you so very much Doctor for having a Breast Cancer School for patients. It means a lot me as well as to all of us that has been diagnose with Breast Cancer. I thank you, your caring for sharing also your knowledge and for educating and orienting me on it all. May God Be with you and us!

  • @kinky_Z
    @kinky_Z 10 месяцев назад +9

    What about keeping carbohydrates below 20g/day as described in Dr Seyfried's "Cancer as a Metabolic Disorder" instead of chemo, and radiation?

  • @artiemurillo47
    @artiemurillo47 3 года назад +14

    Thank you this video was so helpful in our journey through this, God is good, All the time, all the time God is good!!

  • @Moon0552
    @Moon0552 7 месяцев назад +9

    I will be taking letrozole pretty soon and I am soooo scared bc I’ve heard the side effects are horrible 😢I just want to feel good and be happy! I think I’ve suffered enough with this damn cancer!

    • @jenmoore5571
      @jenmoore5571 4 месяца назад +2

      Hello, when i started taking them 3 yrs ago i took them in the evening and they made me feel a bit sick, so i spoke to my local Doctor and he suggested to change the time of taking, so now i take them every day at 12 mid day. I have an alarm on my phone to remind me also i purchased a seven day pill box as before that i could not remember if i had taken. I have got a few more aches in my body and have put on a little weight that is all i have noticed. You will get through this i rename my pills as my energy pills. 😊

    • @user-ck9ng8tp4l
      @user-ck9ng8tp4l 3 месяца назад

      Goodluck, I am on a forum a friend got pancreatic cancer on that and died. So many others same

    • @lauraarciga7783
      @lauraarciga7783 Месяц назад

      I’m on letrozole and so far so good.. I move my body a lot and drink tons of water..
      But most importantly I TRUST GOD

  • @Terege16
    @Terege16 Год назад +3

    I love this doctor and wish he would be my doctor . His videos are so informative and educational for those who have been diagnosed with breast cancer like me. He seems like a very professional, caring, knowledgeable doctor

  • @josierazon5971
    @josierazon5971 2 года назад +12

    Thanks a lot doc for a very enlightening discussion. Hopefully all of us recovered the soonest possible time. May God healed us all.

  • @le13579
    @le13579 3 месяца назад +5

    These videos were a huge benefit in preparing me for my cancer treatment. I watched them after surgery but before I met my oncologist.
    The videos became the basis of my research and armed me with the knowledge to ask heaps of targeted questions as well as gave me a strong understanding of the biopsy and surgery results.
    Timing was important for me. Once chemo started I didn't want to know about anything or do any further research.
    Thank you so much for the fantastic, calm content.

  • @1979hellcat
    @1979hellcat 5 лет назад +23

    I been diagnosed w HER2 triple positive breast cancer. I have 2 rounds of chemo left out of 6, many months of immunotherapy drugs to do, and I’ll b on hormone therapy for years. I’m also BRCA 1 & 2 negative (thank God), and I’m still trying to do a full hysterectomy and double mastectomy (not at the same time) - I’m also switching my eating habits a lot and switched to purified drinking water only. I’m going to do everything I can to not have a reoccurrence of cancer. ❤️

    • @BreastCancerSchoolforPatients
      @BreastCancerSchoolforPatients  5 лет назад

      Good luck. Thanks for supporting our educational outreach. Nice to know it has helped you. Make sure to visit our entire video based Breast Cancer School for Patients to learn more about your unique situation. www.breastcancercourse.org

    • @honeyb7631
      @honeyb7631 3 года назад

      How are you doing now? Hope all is well💕💕💕

    • @adl9260
      @adl9260 2 года назад

      Water has taste to it.
      Purified does not, please call me.

    • @shalommagalore783
      @shalommagalore783 2 года назад +3

      God keep you and heal you in Jesus name amen❤️

    • @SCLana
      @SCLana 2 года назад +4

      How are you today? I have a same diagnosis and I want to skip the chemotherapy. Thank you

  • @sheebasebastian5874
    @sheebasebastian5874 4 года назад +4

    Big salute doctor ! Love from India .

  • @nourbus
    @nourbus 4 года назад +3

    Great lecture John. Thanks

  • @ceciliakowalewski7775
    @ceciliakowalewski7775 4 месяца назад +1

    Thank you so much Dr. William. Your videos are very informative. You are wonderful, you explain everything very clearly with all the information. What state are you now Dr. William?

  • @pattidugger6885
    @pattidugger6885 Год назад +5

    So overwhelmed!

  • @rashafaraj8825
    @rashafaraj8825 2 года назад +3

    Great video. Thank you! Do you think hormonal therapy might benefit me in case of Er negative and Pr +ve (only 3%). I am already on hercipten and pergeta now after chemo+targeted are done. Grade 4 breast cancer.

  • @jazmindelacruz2912
    @jazmindelacruz2912 4 года назад +23

    Thank you so much Doctor. You are very knowledgeable and patient , I enjoy watching your videos and learning a lot, I'm starting my radiation next week, also oral endocrine. You are such an angel, God bless you.

    • @BreastCancerSchoolforPatients
      @BreastCancerSchoolforPatients  4 года назад +4

      You are too kind. Make sure to visit the Breast Cancer School for Patients for more information. www.breastcancercourse.org. Good luck.

    • @jilltrenholme5576
      @jilltrenholme5576 3 года назад +1

      Hope you are OK

    • @jazmindelacruz2912
      @jazmindelacruz2912 3 года назад +3

      @@jilltrenholme5576 I am :) , just had a mammogram last month and there is nothing bad :) .

    • @ashrav8526
      @ashrav8526 3 года назад +1

      My mom is taking chemotherapy now....Will she be fine???I'm tensed about her...

    • @ailenecaluttung1208
      @ailenecaluttung1208 Год назад +1

      Hi jasmin,how r u?how’s your radiation

  • @mayokloves7550
    @mayokloves7550 4 года назад +4

    Very Informative, many thanks Doc.

  • @nancymoore8363
    @nancymoore8363 2 года назад +3

    Hi, was recently diagnosed with a situ tumor which was removed. I am 69. 20yrs ago I had a right sided AVM bleed in my brainstem (peduncle). I am very blessed not to have needed surgery. Some side effects which are 90% gone.
    I have broken several bones after the age of 50.
    Wishing for guidance.

  • @bettycaparangca193
    @bettycaparangca193 3 года назад +2

    Thank you doctor ,for giving me info.I am stage 4

  • @seektruth983
    @seektruth983 2 года назад +6

    Would drastic lifestyle changes to control insulin levels (which influence estrogen based breast cancer) be a viable substitute for hormone therapy?

  • @katelo8404
    @katelo8404 5 лет назад +6

    Thank u sooo much for sharing with us your knowledge🙏 I would like to have you as my doctor....bless you❤️

    • @BreastCancerSchoolforPatients
      @BreastCancerSchoolforPatients  4 года назад

      Thank you for the feedback. Make sure you visit the complete Breast Cancer School for Patients. Same video lessons, but organized in the order of topics you will experience them. www.breastcancercourse.org/

  • @monikaengel5515
    @monikaengel5515 5 лет назад +11

    What a great and positive videos thank you 🙏

    • @BreastCancerSchoolforPatients
      @BreastCancerSchoolforPatients  5 лет назад +1

      Make sure to visit our entire video based Breast Cancer School for Patients to learn more about your unique situation. www.breastcancercourse.org

  • @laureeniannucci4878
    @laureeniannucci4878 6 дней назад

    Very informative. Thank you for the info.

  • @aliceeckardt6727
    @aliceeckardt6727 4 года назад +24

    We already know about the joint pain, insomnia and weight gain but could you please address the cognitive impairment caused but these drugs.

    • @lindadrothwell237
      @lindadrothwell237 3 года назад +1

      About 4 years ago I was diagnosed of OVARIAN CANCER and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including OVARIAN CANCER , at first i doubted if it was real but decided to give it a try, when i contact this herbalist via his email and he prepared an OVARIAN CANCER herbal cure and sent it to me via UPS delivery company service,when i received this herbal cure, he gave me step by directions on how to apply it, when i applied it as instructed, i was totally cured of this deadly disease within 5 months of usage, I am now free from CANCER DISEASE ,all thanks to Dr Harvey Herbal World,you can also reach this great herbal doctor for help . He can help get rid of yours permanently.. Also specialize in treating all kinds of illness, HERPES VIRUS, HEPATITIS B, CANCER, BRAIN DISEASE, INFERTILITY, DIABETES AND MORE. .... I want to anyone suffering from Cancer to contact Dr Harvey via {Drhavrveyphytotheraphy@yahoo.com)
      Website link: Http://drharveyherbalworld.blogspot.com
      WhatsApp:C+1 475 522 1289) All thanks to him that I didn't give up on life.

    • @tigertoxins584
      @tigertoxins584 2 года назад

      thats a very broad definition of effects

    • @thewestcoastwizard1
      @thewestcoastwizard1 9 месяцев назад

      Wow amazing. My favorite..I love the grounded reality of this channel!!. Greetings,from Mr Axel Vasa.❤

  • @swalker1348
    @swalker1348 7 месяцев назад +2

    Thank you. I had been putting off the anastrozole since my mastectomy in July and I’ve decided to give it a try. I had er pr + her2- IDC. My mother had triple negative BC, so didn’t have this option. She is a survivor and I’m hoping I will be as well. I have that I have to see an oncologist for several years, or forever, but that’s my new normal.

    • @user-ck9ng8tp4l
      @user-ck9ng8tp4l 3 месяца назад

      Anastrozole became too debilitating after 16 months, month break put on Tamoxifen, 15 months and found a Pulmonary Embolism. It is BS him saying there’s hardly any side effects. I’ve just had a MRI my spine is stuffed

  • @indiancitizen8297
    @indiancitizen8297 2 года назад +9

    Please pray for me

    • @lizahennke9296
      @lizahennke9296 Месяц назад

      Sending prayers. Now you pray to our Lord as well. Your faith is amazing for healing, more than others praying for you❤❤❤ be blessed.

  • @SofiaAhmad-rp8sm
    @SofiaAhmad-rp8sm 8 месяцев назад

    Thanks for the informative video

  • @graceabuan-tiew1918
    @graceabuan-tiew1918 3 года назад +4

    If estrogen is positive HER2 is negative and Score 0..what is the best treatment for this

  • @DoesItReallyMatter25
    @DoesItReallyMatter25 7 месяцев назад +1

    Thanks for this information, Doctor. Any info for ES/PR+ HER2- breast cancer in a 35 yo pregnant woman? 😵‍💫😫

  • @sunlife6925
    @sunlife6925 2 года назад +1

    So easy to understand❤tnx a lot

  • @sabreena1khalick
    @sabreena1khalick 5 лет назад +33

    Thank you so much for your excellent videos. I've just been diagnosed with invasive ductal carcinoma. You are a Godsend. I'm better prepared for my cancer journey. God bless you.

    • @BreastCancerSchoolforPatients
      @BreastCancerSchoolforPatients  5 лет назад +6

      It is a tough road ahead, but know you will get to the other side one day.

    • @vals74
      @vals74 5 лет назад +2

      StarlightnDust - We seem to be on the same road...me too ☹️

    • @sabreena1khalick
      @sabreena1khalick 5 лет назад

      @@vals74 hi, good luck and good future health to you. I wish you the best of luck. We can beat this! 💪

    • @abigailpmm1182
      @abigailpmm1182 5 лет назад +5

      @@sabreena1khalick Two years ago, I got my diagnosis: stage one, grade two. Best Wishes to you all.

    • @kajalmatlani8240
      @kajalmatlani8240 4 года назад +2

      All the best to all

  • @deborahbalitang199
    @deborahbalitang199 6 месяцев назад

    I was diagnosed with Invasive Ductile Carcinoma, ER -, PR +, HER 2 -. I am postmenopausal. Do you recommend Hormone blocker in my case?

  • @knowfacts9214
    @knowfacts9214 2 года назад

    Doc, I need help. I was diagnosed BC stage 3. ER 8 (5+3) PR 4 (2+2) HER 2 negative. Neo adjuvant, chemotherapy not successful( 6 cycle ) tumor removed 10 x 11.3 x2.7 cm. Recommend Radiotherapy +Hormonal Therapy.. but I decided to do skip Radiotherapy and I choose directly to Hormonal therapy

  • @mutegabriel4812
    @mutegabriel4812 2 года назад +1

    Thank you Doc.🙏🙏🙏

  • @AnAM547
    @AnAM547 4 года назад +2

    Thank you 🙏.

  • @kristinernstsen7841
    @kristinernstsen7841 3 года назад +4

    And how is the psycological side effectes? Moods? Are many prescribed antidepressants?

  • @rababhassan5349
    @rababhassan5349 3 года назад +2

    Thanks 👍

  • @essentialdistribution4484
    @essentialdistribution4484 Год назад

    Thanks from Romania.

  • @Vickygarcia73
    @Vickygarcia73 3 года назад +10

    Got diagnosed with stage 2, grade 3 with invasive ductal carcinoma....going for left breast mastectomy on 08/25 🙏🏼

    • @rbayesey
      @rbayesey 3 года назад +1

      How did you go Vicki I am the same just had left breast mastectomy last week about to start chemo next week

    • @irenefaith7421
      @irenefaith7421 2 года назад

      @@rbayesey any update mam

    • @rbayesey
      @rbayesey 2 года назад +3

      @@irenefaith7421 still fighting , managed 4 A/C 12 weekly taxol , and rads still here ! 🎀🌱

    • @SofiaAhmad-rp8sm
      @SofiaAhmad-rp8sm 7 месяцев назад

      ​@@rbayeseyhello,how are you doing,I diagnosis breast cancer grade 3

  • @aarti3379
    @aarti3379 3 года назад +1

    Thank you so much 🙏

  • @Classyladyjazz86
    @Classyladyjazz86 2 года назад

    What if I'm positive for both estrogen and progesterone

  • @seektruth983
    @seektruth983 Год назад +9

    I wish there was a baseline recurrence risk tool, to know what your risk is without medication. But also that by now there would have been research showing that a smaller dose of hormonal therapy would benefit persons with a much smaller frame and BMI which could reduce the risk of unnecessary side effects.

    • @conniejohnsoncj8724
      @conniejohnsoncj8724 Год назад +6

      I agree! A one size approach to AIs yet there is so much talk about our unique tumor receptors, size, stage etc. maybe that’s the solution for less side effects? Has anyone studied that?

    • @kamashbrendah8228
      @kamashbrendah8228 Год назад +1

      Hey I have pained in breast

    • @CCClubSC3
      @CCClubSC3 8 месяцев назад +6

      I so agree with this. I called Oncotype and asked them what my score would be without a hormone blocker and the person said they don't test for that. They only give you a score if you take the drug. Makes me wonder if they get a kickback for pushing the drug? Also I read where a person asked her Doctor if they prescribe the same amount of hormone blocker for a 150 pound woman as a 300 pound woman and he said YES! Unbelievable!

    • @sheila7814
      @sheila7814 4 месяца назад +3

      @@CCClubSC3You are right in asking! Estrogen is made in the ovaries, adrenal glands and fat tissues. If someone is 300 pounds they will have quite a bit more estrogen than a person that is 110 pounds. Absolutely does not make sense on the dosage!

    • @user-ck9ng8tp4l
      @user-ck9ng8tp4l 3 месяца назад

      There is a Tool called Predict Breast, it’s from Cambridge University UK, they are currently working on version 3, I’ve been in contact with them as version 2 did not include radiation, 3 will. I’ve had a Professor email me keeping me updated. Type in to google Predict Breast and it’ll take you to the Tool to put your information in.

  • @bradandlesiacoats928
    @bradandlesiacoats928 4 года назад +2

    Thank you for these videos. My OC is good but it helps hearing this and knowing it is going correctly. IBC, IDC, cancer with 2lymph nodes involved. I will keep taking that sticking pill for my 10 yrs as I do not want this back

    • @bendmymind486
      @bendmymind486 3 года назад

      Larose Murphy Hi. Source please showing percentages of how many have cancer come back? I’m just trying to learn. Tks

    • @Katsem
      @Katsem Год назад +1

      I took it for 5 years, and offered to go for 7, but my oncologist didn’t think it was necessary. Maybe he balked because I had developed osteopenia. After I stopped the Anastrozole the osteopenia reversed. Well, the cancer came back. So I’ll be taking the aromatase inhibitor again for 5 years.

    • @user-ck9ng8tp4l
      @user-ck9ng8tp4l 3 месяца назад

      As my Radiation Oncologist said just the other week, there’s no guarantee with these drugs, I’ve stopped they’re debilitating and caused other problems. Your cancer recurrence would have anyway, the tablets don’t kill the cells, just delay

  • @charlotteruse158
    @charlotteruse158 3 года назад +14

    So hormone therapy for post menopausal women is going to cause more bone density loss than what is already occurring? Then we fall and break a hip and it's over, lol. Sorry. I have to laugh. All of these things to consider. Quality versus quantity. I don't know.

    • @sheila7814
      @sheila7814 4 месяца назад +1

      There are some things that can be done. My bone density has improved so far. I started walking (quite a few miles a day 6-8), I do strength training with weights, use a vibration plate, Jump and climb stairs, take vitamin D3, calcium and occasionally take vit K. I eat prunes (5-6 a day have been shown to improve bone density…. But be careful with prunes and nuts…. Your potassium can get too high because the anastrazole messes with adrenal hormones that control your salts.). I check my blood work more often than the doctors do and go to a lab like LabsNow. I cut out sugar, white bleached flour products, and processed foods. I feel wonderful now! I also feel like the pill is keeping me safer.❤

  • @delizzy107
    @delizzy107 5 месяцев назад +1

    Nettle root, grape seed extract, Calcium D-Glucarate , Chrysin, Indol 3 Carbonal for me

  • @wendyfield7708
    @wendyfield7708 Год назад

    Does the hormonal therapy reducing the oestrogen result in a hairy body, and isit worth it for an otherwise healthy but arthritic 89 yearold?

  • @vishyswa
    @vishyswa 4 года назад +18

    I switched to Tamoxifen after 6 weeks on Femara. Femara is an aromatase inhibitor and it nearly did me in with severe and painful side effects. It was much harder on me than chemo. Was on Tamoxifen for 5 years with no adverse effects other than the occasional hot flash.

    • @BreastCancerSchoolforPatients
      @BreastCancerSchoolforPatients  4 года назад

      Make sure to visit our entire video based Breast Cancer School for Patients to learn more about your unique situation. www.breastcancercourse.org

    • @sonalisrivastava4781
      @sonalisrivastava4781 2 года назад

      @vishyswa Maam, are you from India? Where have you got yout treatment?

    • @vishyswa
      @vishyswa 2 года назад +8

      @@BreastCancerSchoolforPatients My experience was in no way "unique". My oncology nurse told me that aromatase inhibitors had put some women in wheelchairs! She was just being honest. My oncologist kept revising to a higher percentage the patients who were negatively affected. Each successive visit he admitted to a 5% increase, seemingly with reluctance. The drug companies have some doctors in their back pockets..

    • @vishyswa
      @vishyswa 2 года назад +5

      @@sonalisrivastava4781 No, I am from Seattle USA and got my treatment at Swedish Cancer Institute, one of the best. Btw, I didn't ASK my oncologist if I could switch to Tamoxifen -- I TOLD him.

    • @sonalisrivastava4781
      @sonalisrivastava4781 2 года назад +1

      @@vishyswa Thankyou for your kind reply. My mother completed her treatment in Jan this year, and was taking letrozole, but after two months of treatment she developed a hard area at the site of operation, after biopsy they are saying that it's local recurrence, change her medicine to tamaxifen and said she may require cdk4 after surgery. We are actually very much disturbed, how can recurrence occur in one year even while taking letrozole, Maam, have you heard any such case and the treatment protocol for it? I researched on internet that letrozole is good for er +ve, her -ve post menopausal BC. Your reply would be precious for us.. Praying for your good health🙏

  • @wendyfield7708
    @wendyfield7708 Год назад

    Thank you.

  • @marionraine3703
    @marionraine3703 10 месяцев назад +1

    Doctor I'm oestrogen positive on a 7 mm breast lump
    Had fulverstrant injection 3 years .. horrific night sweats,no sleep
    On Equisin tabs now fwew months but incredibly painful joints hads bcannot get up from a sitting position..know I have to continue for 10 years
    I'm 68 and bones degenerative plus oesteoporis spine..so as far as I know there is no remedy for bones⁉️what now?
    Kindly M

  • @Fun_shorts708
    @Fun_shorts708 2 года назад

    Are Tnbc patient need any hormonal or anti hormonal therapy after surgery chemo and radiation therapy ????

  • @sunlife6925
    @sunlife6925 2 года назад +1

    Thank you so much😘

  • @amyvillalobos1863
    @amyvillalobos1863 Год назад +1

    What about ER-/PR+?

  • @kaypierce8593
    @kaypierce8593 2 года назад +1

    But if your miserable taking them is it really worth it. If I have hotflashes and weight gain again I probably won’t do it’.

  • @sidneysoon2745
    @sidneysoon2745 Год назад

    When to start treatment after stage 2 breast cancer been diagnosed?

  • @juaquiene7726
    @juaquiene7726 Год назад +5

    Was in hopes of hearing from someone who had serious side effects from Anastrozole.
    So many of these drugs have similar side effects. What choices do I have if I can't tolerate the side effects?

    • @bosslady5163
      @bosslady5163 Год назад +5

      I’m on my third year of taking Anastrozole and so far no noticeable side effects. Work with your oncologist if side effects are bothersome. Stay strong.

    • @Jane-xd3nw
      @Jane-xd3nw Год назад +2

      Year three on Anastrozole and just now having many side effects but hangin in there for the 5 yr mark.

  • @raianamahjabin9529
    @raianamahjabin9529 5 лет назад +9

    Does hormonal therapy effective on metastatic breast cancer?

  • @kemjelavenir3643
    @kemjelavenir3643 4 месяца назад

    I am diagnoised of liminal A breast cancer. Done 3 rounds of chemotherapy but feel reallong weak. Will have to start a homonal therapy. A little bit worried caused of the pains i feel now. Dont know how to go through all this

  • @sheila7814
    @sheila7814 4 месяца назад +1

    I bet this doctor does not rush you in and rush you out when you are at his doctor’s office. I was still asking questions as mine was walking out the door. Not a good feeling and not enough in my city to find another unless I traveled and then….. insurance would say “Out of Network”

  • @MegInCa
    @MegInCa 4 года назад +16

    I appreciate the video. I have to say, I’m not sold on it at all. Reducing recurrence by half with all the establishes side effects, paired with the unknown both short and long term. I think there are better gambles out there.

    • @BreastCancerSchoolforPatients
      @BreastCancerSchoolforPatients  4 года назад

      Take a look at this page and video www.breastcancercourse.org/patient-driven-health-care/ . Whatever decisions you make when you are well informed is the correct decision for you.

    • @andredarin8966
      @andredarin8966 4 года назад +12

      Margaret. The difference between 20% and 10% is not 50%, it's 10%. This is a common misinterpretation of data that suggests a modality is more efficacious than it actually is. If you want a real eyeopener, check out the online tool "Predict" (breast.predict.nhs.uk/tool)
      You'll be required to know 10 variables of your breast cancer. I used this tool--considered very accurate by clinicians to predict survival--for a woman I know. To cut to the chase, after having a segmented mastectomy and passing on Tamoxifen, this tool predicted a 1% advantage of survival taking Tamoxifen at five years, a similar advantage at 10 years, and a 2% advantage at 15 years! I found this shocking. I researched articles reviewing the accuracy of Predict and found it was likely to OVERESTIMATE mortality.
      I have seen this sort of statistical legerdemain more times than I would have liked to. The 50% advantage is the result of simple math: (20%-10%)/20%. However, if you look at it like this, you see something quite different:
      .20
      -.10
      _______
      .10
      That's 10%, not 50%.
      Add to this problem that 40% of women will not respond to Tamoxifen (currently there is no way of knowing which patients will), and the cancer patient has effectively entered a high-stakes lottery.
      I might also suggest that according to the journal "Cancer", approximately 22% of women stop taking Tamoxifen the first year due to side effects and 35% after 3 1/2 years. When you consider side effects include those that mimic menopausal symptoms and are prevalent among some patients , but not all women who take the drug, including hot flashes, vaginal discharge, irregular menstruation, headaches, fatigue, nausea, vaginal itching and rashing, there's an important issue that must be addressed.
      Oxana Palesh, Ph.D., a research assistant and professor of Radiation Oncology and Psychiatry at the James P. Wilmot Cancer Center at the University of Rochester Medical Center stated,
      “Extended periods of stress and trauma and its resulting cortisol production may interfere with the body’s ability to fight off cancer progression. When there is consistent, long-term stress in the body, the elevated cortisol level may can change the body’s normal rhythms and potentially reduce resistance to tumor growth.”
      I'm assuming interrupted sleep from hot flashes and nausea that interferes with obtaining the nutrition the cancer patient needs are highly stressful--as are the other side effects-- and one would think, immunosuppressive.
      This is a tough call for women, no doubt. While data is not information, the numbers crunched from tools like Predict and the 40% failure rate of Tamoxifen must mean something.
      Like you, were I a patient with this diagnosis, I would not find the case for adjuvant hormonal therapy persuasive or compelling. I'd turn over every rock looking for a different
      option.

    • @lidamooini2064
      @lidamooini2064 4 года назад

      Exactly!

    • @andredarin8966
      @andredarin8966 4 года назад +3

      ​@Sarah Moul You are to be commended for doing a deep dive into the numbers. M

    • @natureandhappiness3846
      @natureandhappiness3846 3 года назад +4

      Cow milk increases breast cancer risk by 80%. Avoid dairy products.

  • @ginaherdlcswranxietyclass9213
    @ginaherdlcswranxietyclass9213 4 года назад +7

    You did not discuss post vs pre menopausal women and the sexual side effects for both.

  • @tanyajackson372
    @tanyajackson372 8 месяцев назад

    I get breast pain but this month is been very painful...pms...im going to get another test....i hope its not breast cancer

  • @Vatche-O
    @Vatche-O 2 года назад +4

    Thank you so much for this great lesson.
    I have a question.what if someone is ER+ /HER2- and chooses hormonal therapy for 5-10 years,but the cancer comes back.what will be the approach then?

    • @biancacalabria
      @biancacalabria 2 года назад +3

      I could be mistaken, however, I would assume that person would need a mastectomy as well as more aggressive form chemotherapy.

  • @nooreaman5003
    @nooreaman5003 Год назад +2

    Thank you for lovely explanation Dr. "Your words are very important to me and I try hard to understand them, but the sound of your music doesn't allow me to focus and takes my senses away. Please, for your future videos, if you don't include music, I will be able to understand your words better."

  • @luzdobens9788
    @luzdobens9788 2 года назад +4

    is a scientific evidence show there is more the side effects then benefits.

  • @ashimabehera1669
    @ashimabehera1669 2 года назад

    How many chemotherapy in 2 stage breast cancer patains

  • @suzanneturley4433
    @suzanneturley4433 2 года назад +5

    I’ve been diagnosed with Invasive Ductal Carcinoma and it’s HER2 negative. My Consultant said I would have a lumpectomy with a removal on the inner side as I have two types of cancer in the one breast. This would be followed eventually by Radiology and Ten years of Hormonal Treatment. I’m considering a right side mastectomy as the ongoing worry, sleepless nights, etc has been the worst I have ever known. I would welcome your knowledgeable thoughts about this. I see my Consultant in 5 days time to give her my final decision. HELP

    • @XXX-cq9uj
      @XXX-cq9uj Год назад +4

      I'm in same boat right now. Surgery on Tuesday. I'm scared

    • @thankfulblessed3774
      @thankfulblessed3774 Год назад +2

      This is exactly a type of cancer I have I have recently been diagnosed two weeks ago with invasive ductal carcinoma ER/PR + HER2 -...I just went to see my surgeon today literally three hours ago and they’re telling me that I need to have an MRI done and also that I will definitely be taking hormones for a long time they’re also telling me that I have to have my nipple completely removed with Lumpectomy. but I’m wanting to also choose the mastectomy. From what I have researched the invasive estrogen positive top breast cancer is one that can come back very easily, and I have seen several other women on RUclips sharing their breast cancer stories stating how they had lumpectomy’s only later to have to have a mastectomy anyway so I’m figuring let’s just go ahead and get it over with to reduce as much risk as possible possible!! I’m also wondering if any of you women I’ve had severe arm pain in my right arm that is where my breast lump is and also the mass under my arm also I’ve had pain in my side feels like small nodules or mini cysts, It hurts severely to the point that I can’t even go anywhere now hardly at all without pain medication all day?? They haven’t even tell me what stage my cancer is in yet

    • @bosslady5163
      @bosslady5163 Год назад +1

      @@thankfulblessed3774Hello, I hope you’re doing well. Stay strong.

    • @suzanneturley4433
      @suzanneturley4433 11 месяцев назад +3

      Hi all, well I went back to my Consultant complete with a list of questions which basically required Yes or No answers bar one which was explained fully by my Consultant. She then said ‘So are we all ready for Friday’? To which I replied ‘I am, on one condition. In 8 months time I will be 69 years old and I have no time for vanity; therefore, I think that the best thing for me would be to have a right side mastectomy….which the Consultant was more than happy to do. I saw her again about six weeks later, and her first words to me was ‘You don’t know what a brilliant decision you made. As I explained to you that I would be removing a lymph node for testing and on your first lymph node was a microscopic amount of cancer, but lymph node 2 & 3 were clear’. Also, due to medication that I have to take daily for a different condition, Chemotherapy and or Radiotherapy was out of the question so it was straight onto an aromatase called Anastrozole, one tablet daily for five years. I have been extremely lucky in that I have not had any side affects from this medication; however, my thoughts and prayers are with you all if you are going through this same ‘walk’ in our lives. ❤

    • @marives8
      @marives8 3 месяца назад

      ⁠@@suzanneturley4433hope you are doing well & no side effects from hormone therapy🎉

  • @SCLana
    @SCLana 2 года назад +1

    Our doctors prescribed everything same for most patients:(

  • @shahwarhamdani9781
    @shahwarhamdani9781 Год назад

    You are talking about these treatment after Surgery.

  • @monikaengel5515
    @monikaengel5515 4 года назад +5

    I just start 3 months ago zoladex and anastrazole hate side effects:hit flashes,fatigue, change moods, sleep problems but need to learn to live with that keep cancer away.

    • @natureandhappiness3846
      @natureandhappiness3846 3 года назад +1

      Cow milk increases breast cancer risk by 80%. Avoid diary products to keep cancer away.

    • @monikaengel5515
      @monikaengel5515 3 года назад +7

      @@natureandhappiness3846 I never drink dairy and get breast cancer it's also stress cause it cortisol and estrogen raise up during chronic stress and food.I never drink, smoke ,always fit exercise 6 days a week no family history

  • @tonygasperson4952
    @tonygasperson4952 2 года назад +1

    What happens after 10 years is up

  • @truman3004
    @truman3004 2 года назад +2

    Having no estrogen SUCKS!!! Horrible hot flashes and anxiety!!!

  • @vals74
    @vals74 5 лет назад +4

    I would just like to thank you for providing this information to newly diagnosed cancer patients.
    It is very complex, and the treatment options can be overwhelming. Your expertise is crucial to patients in making their own decisions. Thank you.

    • @BreastCancerSchoolforPatients
      @BreastCancerSchoolforPatients  5 лет назад +4

      Thank you for the kind comments. Your experience is the exact reason we created the Breast Cancer School for Patients. It is the first video-based platform for cancer that teaches all the complex concepts that patients face. Make sure to visit www.breastcancercourse.org if you have not already. The RUclips videos are all organized in the sequence you will experience them on the website. It is all free and created for everyone.

  • @patriciajump9511
    @patriciajump9511 8 месяцев назад +5

    I don't like this. There is vested interest at work here. Starts out "pro-hormonal therapy," touts and sensationalizes breast cancer spread, and hardly ever gets around to commenting on sentinel lymph node biopsy, which shows if breast cancer cells have spread out of the breast. The side effects are terrible of aromatase inhibitors. Horrible. Side effects are NOT rare. Yes, genomic testing is indispensable. Helps guide treatment. Again, I do not like this talk. He talks like he works for a drug company.

  • @honeyb7631
    @honeyb7631 3 года назад +4

    Well what happens when you have to come off the drugs?

    • @blessingasmawomomoh8501
      @blessingasmawomomoh8501 2 года назад

      I Have All Of These Symptoms But Currently Waiting On My Appointments So I Can Be Diagnosed I'm Having A Hard Time Accepting The Conceiving Part Because I Really Want A Baby but with the help of DR RORPOPOR HERBAL on RUclips medications am Cured from hormones- PCOS🌱🌱🌱 ruclips.net/channel/UCkZwKW6qES4dXDWzb0YQErA

  • @giancarlobazzano8088
    @giancarlobazzano8088 5 лет назад +2

    IDC 2cm in size. ER+ PR+ HER2- .Can mastectomy or any kind of surgery be avoided and just do light chemo or hormone therapy? Thank you so much for your helpful videos

    • @abigailpmm1182
      @abigailpmm1182 5 лет назад +3

      It's best to have it taken out. I was really glad about my surgery.

    • @melatnigatu1984
      @melatnigatu1984 Год назад

      @@abigailpmm1182 I hope u doing well❤️

    • @jasminarcenas4681
      @jasminarcenas4681 Год назад

      I was also diagnosed with IDC stage 2B .. had mastectomy @ my left breast and started having 1st cycle of chemotherapy last april 20, but suddenly wasn't able to continue my 2nd cycle of chemotherapy yesterday because after recieving my pre op meds, my heart palpitates .. my pulse rate was high and my Doctor decided to temporary hold my chemo.. i was wondering if anyone here also experienced mine? I am from Philippines

  • @marlenehadden8896
    @marlenehadden8896 Год назад

    How serous is stage 3 cancer

  • @rinapaul8936
    @rinapaul8936 2 года назад

    can I take tamoxifen before surgery?

    • @blessingasmawomomoh8501
      @blessingasmawomomoh8501 2 года назад

      I Have All Of These Symptoms But Currently Waiting On My Appointments So I Can Be Diagnosed I'm Having A Hard Time Accepting The Conceiving Part Because I Really Want A Baby but with the help of DR RORPOPOR HERBAL on RUclips medications am Cured from hormones- PCOS🌱🌱🌱 ruclips.net/channel/UCkZwKW6qES4dXDWzb0YQErA

  • @rababhassan5349
    @rababhassan5349 3 года назад

    My tumor receptor is o&p positive

  • @billierpaxton9260
    @billierpaxton9260 2 года назад

    Double mastectomy 7/9/21
    Invasive micropapillary carcinoma
    ER +, PR +, HER -, Ki - 67 +20%
    66 1/2 yrs old

  • @parijame5807
    @parijame5807 11 месяцев назад

    Hi thank you for being every body doctor.
    I am 67 yer old in Jan 23 I was diagnosed grade 2 invasive ductal carcinoma,whit tumour ER8,PR7 HER2 NEGETIVE and normalaxilla
    Inapril I had lumpectomy and 2 lymph node removed .tumour was bigger than 2cm and 2lymph nods was cancerous.
    I had mastectomy in May 14 lymph node was removed, which was clear. Just 2mm cancer cells found in pathology.
    I,m going to have 5 radiotrapy next week.is 4 weeks I have started taking tamoxifen.
    Can I have cod liver oil or fish oil supplement?
    Thank you .

    • @parijame5807
      @parijame5807 11 месяцев назад

      Surrey for my poor English

  • @mon2863Hamilton
    @mon2863Hamilton 2 года назад +6

    It’s amazing how these doctors present chemotherapy, radiation therapy and hormonal therapy as if they are the only and best solutions regardless of the horrific and potential damaging side effects!!! Not to mention the cost (charges) and money made by these doctors. It’s Al funny not funny how you will not have access to these so called “Therapy” if you do not have insurance and tons of money for your insurance deductible!!! 😤

    • @lilianaarredondo7531
      @lilianaarredondo7531 Год назад +1

      Absolutely true, my doctor told me about the hormone therapy but he doesn’t mentioned any side effects, then I was able to investigate and we talked about the dangerous side effects and possibly ways to prevent or protect my body 😢

    • @patriciajump9511
      @patriciajump9511 8 месяцев назад +2

      He says "everybody" needs hormonal therapy for ten years. Well, sometimes you do, but sometimes you don't. He is too pushy, too one-sided, does not give a complete and balanced talk about hormonal therapy. I don't like this talk. He is smarmy. Talk it over with YOUR doctor.

  • @shahwarhamdani9781
    @shahwarhamdani9781 Год назад

    Her,2 receptor negative and Estrogen and progesterone strongly positive

    • @shahwarhamdani9781
      @shahwarhamdani9781 Год назад

      What is the prognosis after mastectomy and with hormonal replacement therapy.

  • @michellemorin644
    @michellemorin644 4 года назад +6

    Why isnt any one adressing the Anxiety?

    • @andredarin8966
      @andredarin8966 4 года назад +4

      The simple answer? The longer-term psychological impact of cancer and its treatment has received comparatively little research. Researchers are far more interested in a drug's efficacy (or lack of it) and its side effects. Evidence Based Medicine has become an almost compulsory practice to harvest data from large numbers of patients and dial it down to the individual but without considering the emotional side of the equation.

  • @yenovaboulgarian6793
    @yenovaboulgarian6793 4 года назад +1

    I’m very sorry but after chimo and hormonal therapy my cancer is back right after 1,5 year ... my doctor told me ...”well it didn’t work for you and we should stop hormonal therapy” ... chimo didn’t as well but why they still want me to do chimo again since none of therapies didn’t work for me ? First place my cancer was because of my hormones ....

    • @kristinernstsen7841
      @kristinernstsen7841 3 года назад

      would love to hear more about your jounrney, i just started

    • @anushak3890
      @anushak3890 6 месяцев назад

      Hi very sad to hear I would like to know more about your journey

  • @Optimization_Coach
    @Optimization_Coach 3 года назад +2

    Losing the rhythms of your natural cycle sets many women up for breast cancer. That cycle is protective at the cell signaling level and when you LOSE or STOP that rhythm odds increase for these diagnoses exponentially. Women experience the greatest risk of Breast Cancer between the ages of 45-65 folks..? What happens in these times? Hormone dysregulation and deficiencies. Keep the rhythm! Replace the lost hormones to include, THYROID, Testosterone, E2 and Pg. Be well....

    • @charlotteruse158
      @charlotteruse158 3 года назад +1

      Ya.....but there are a lot of risks in taking hormone replacements too. Strokes, blood clots, heart disease, heart attacks, breast cancer. I'm not saying it's all bad. I have been considering it myself.

    • @Optimization_Coach
      @Optimization_Coach 3 года назад +1

      @@charlotteruse158 a few books to read would be ESTROGEN MATTERS, SEX LIES AND MENOPAUSE. Remember that all the studies such as WHI use synthetic estrogen and progesterone and not identical hormones.

    • @charlotteruse158
      @charlotteruse158 3 года назад

      @@Optimization_Coach Thank you I will look for those. I do remember asking my physician about estrogen supplements and she said all it does is alleviate the symptoms or prolong the inevitable and that I should just get it done and over with. None of us want to be grumpy, walk around in a brain fog, lose our waistline and put on weight in places we never ever would have imagined. I have to laugh. Then voila you're diagnosed with breast cancer. Thank you for the suggestions. I read a lot and right now this is the area that I am focusing on.

  • @scgraves98
    @scgraves98 3 месяца назад

    😭😭 I don’t want the hot flashes

  • @nenitapis-an6869
    @nenitapis-an6869 5 лет назад +1

    HELP ME ALSO,I"VE DIAGNOSE DUCTAL CARCINOMA,ALSO I DONT HAVE MONEY FOR THE PAYMMMMMMMENT OF THHE DOCTOR,PLS HELP ME

  • @katherineharris2080
    @katherineharris2080 8 месяцев назад +1

    I took anastrozole i have severe arthritis and in a lot of pain it has caused me so much more pain. Night sweats. Day sweats walk around half naked. Turned into a,raving bitch.and feel horrible all the time. I am 77 they wanted me to do accupuncturr and take more drugs my a1c went up a point lost 56 pounds not losing now and my belly got so big i hate this therapy. My onco 30 they wont do chemo or radiation i am so upset

  • @homolix
    @homolix 7 месяцев назад +1

    i´m afraid this trending of considering cancer as a genetic disease is not valid anymore. see the studies by michael levin in regard to bioelectrical networks and cancer, where genes are not decisive in this dysfunction.

  • @rachelrae7835
    @rachelrae7835 4 года назад

    Im er pr + and her2 negative,
    What it means?

  • @susieque2190
    @susieque2190 2 года назад +1

    I have ER and PR positive
    her,2 neg.., invasivje. Not foing chemo. 😂

    • @susieque2190
      @susieque2190 2 года назад

      Sorry I can't
      Text . Little nervous

    • @accidentsafe
      @accidentsafe 2 года назад

      I just got the call I have this too.

    • @susieque2190
      @susieque2190 2 года назад +1

      @@accidentsafe I'm so sorry. Surgery doesn't bother me too much but chemo hair falls out and boob scars radiation. I'm a nervous wreck

    • @accidentsafe
      @accidentsafe 2 года назад

      @@susieque2190 Do you know if a double masc will work without chemo and radiation, just hormone therapy? I literally found out 3 hours ago.

    • @accidentsafe
      @accidentsafe 2 года назад

      @@susieque2190 Also I think they can replace boobs with other body fat.

  • @joannechisholm4501
    @joannechisholm4501 5 лет назад +7

    I dont want to be a woman any more (((((

  • @annettuhirirwe1583
    @annettuhirirwe1583 4 года назад +4

    Why the back ground music cant hear properly

  • @tigertoxins584
    @tigertoxins584 2 года назад

    I’m sorry I know this is for a good cause and someone close to me has bc but this guy legit looks like a deep fake

    • @blessingasmawomomoh8501
      @blessingasmawomomoh8501 2 года назад

      I Have All Of These Symptoms But Currently Waiting On My Appointments So I Can Be Diagnosed I'm Having A Hard Time Accepting The Conceiving Part Because I Really Want A Baby but with the help of DR RORPOPOR HERBAL on RUclips medications am Cured from hormones- PCOS🌱🌱🌱 ruclips.net/channel/UCkZwKW6qES4dXDWzb0YQErA

  • @tlspurlen6442
    @tlspurlen6442 5 месяцев назад

    Another pathological liar

  • @lauretaduraj1484
    @lauretaduraj1484 3 года назад

    Thank you doctor 👏❣️