From Janeway’s Immunobiology: CXCR4 does not bind CXCL13 (as you suggest). It binds the chemokine CXCL12, which is produced by the stromal cells of the dark zone, which actually retains the centroblasts in this area for further growth and increased expression of surface Ig. When CXCR4 is downregulated then migration to light zone via CXCR5 and CXCL13 occurs.
Today I watched all your videos about immunology and I feel so smart now. A BIG THANK YOU! This is priceless. Also, a lot of my schoolmates are studying with the help of those videos:) And could you PLEASE upload the next video? I have an exam on Tuesday, pleeeeease!:(
Dunno if anyone gives a damn but if you're stoned like me atm you can stream all the latest movies and series on InstaFlixxer. I've been binge watching with my gf for the last few months =)
I Think you will become a great teacher one day, I hope you will continue to make this video in immuno but also in medical physiology ! If one day you want to visit French medecine faculty, I will be glad to greet you ! Thanks a lot !
Identifty the key molecule and effector cells in humoral immune response? A. Antibody B. Cytotoxic T cell C. Dendritic cells D. T helper cells E. Plasma cells
Where can I buy all your posters? xD Thank you SO much! Studying went extremely slowly, but thanks to you, I finnaly see some structure. Very thankful!!
So is "somatic hypermutation" the reason for there is one specific B cell for every antigen? If not, what is the aim of somatic h.mutation? Can somebody help please
From Janeway’s Immunobiology: CXCR4 does not bind CXCL13 (as you suggest). It binds the chemokine CXCL12, which is produced by the stromal cells of the dark zone, which actually retains the centroblasts in this area for further growth and increased expression of surface Ig. When CXCR4 is downregulated then migration to light zone via CXCR5 and CXCL13 occurs.
Today I watched all your videos about immunology and I feel so smart now. A BIG THANK YOU! This is priceless. Also, a lot of my schoolmates are studying with the help of those videos:)
And could you PLEASE upload the next video? I have an exam on Tuesday, pleeeeease!:(
respect Mr. Armando, i don't what could i do with out your videos
true
Your method's and sketchs are perfect. I learn so much from you
thank you!
Its up now, ill add it to the playlist~
is there a way I can purchase this whole picture?
Dunno if anyone gives a damn but if you're stoned like me atm you can stream all the latest movies and series on InstaFlixxer. I've been binge watching with my gf for the last few months =)
@Devon Lewis Yea, been using instaflixxer for since december myself =)
@Devon Lewis yup, I've been watching on InstaFlixxer for since december myself :)
Your drawings help me understand microbiology better than any PowerPoint presentation - hands down! Thanks
Thank you very much Armando, your videos are very helpful and systematic :)
You were correct the first time: B-cells undergo affinity maturation, not mutation. Brilliant video - thank you :)
I Think you will become a great teacher one day, I hope you will continue to make this video in immuno but also in medical physiology !
If one day you want to visit French medecine faculty, I will be glad to greet you !
Thanks a lot !
You are best. I have learned so much from you. Love from India.
So basically you described all but the interaction and binding with the TCell for activation, which is what I came here for
6:50 real important clip. thanks :)
Identifty the key molecule and effector cells in humoral immune response?
A. Antibody
B. Cytotoxic T cell
C. Dendritic cells
D. T helper cells
E. Plasma cells
E
thank you for these videos! Much respect. you're the reason I'm passing my exams!
Thank You ! makes my studying a lot less painful.
If you were in my class i would steal all your notes... so helpful!
Where can I buy all your posters? xD Thank you SO much! Studying went extremely slowly, but thanks to you, I finnaly see some structure. Very thankful!!
Great video, as always! But at 5:50, affinity maturation actually was correct.
fantastic videos... but they are scattered. i have to look for the next.
Pls share the image of the lecture map in google docs as u have done for complement system. They are of great value for revision.
it helped a lot :)
Perfect!!
Thank you!
this is very good! thanks:)
Thanks bro
So is "somatic hypermutation" the reason for there is one specific B cell for every antigen? If not, what is the aim of somatic h.mutation? Can somebody help please
Thank you :)))
i think i can be an immunologist now.
👌
wowowowowow