Lipidologist Explains: What is Lipoprotein(a) & how does it affect heart health? | The Proof EP

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  • Опубликовано: 19 окт 2024

Комментарии • 16

  • @ÁzsiábaSzakadtam
    @ÁzsiábaSzakadtam 3 месяца назад +4

    This channel is grossly underrated. Amazing guests and topics.

  • @ÁzsiábaSzakadtam
    @ÁzsiábaSzakadtam 3 месяца назад +1

    Please review this article
    The LDL cumulative exposure hypothesis: evidence and practical applications
    Nature Reviews Cardiology

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  3 месяца назад +1

      On my list!

    • @ÁzsiábaSzakadtam
      @ÁzsiábaSzakadtam 3 месяца назад

      @@TheProofWithSimonHill can't wait 😎

    • @gales3899
      @gales3899 2 месяца назад

      I’m hoping the article says don’t worry about your Apo(a). I’m obsessing! Mine is high but I have no other risk factors. Well father dies young but I don’t smoke etc. WFPB VEGAN for 15 years. Run 20-30 miles per week and lift. All other markers look good. (Apo B etc) it would be interesting to see risk factors in a group like myself.

  • @danieljrgensen133
    @danieljrgensen133 3 месяца назад +1

    My shortest answer:
    It's simply a small LDL particle with an added "sticky" protein..... which makes it 600%(according to latest 2024 study) more likely to get stuck whee it shouldn't, compared to the other "regular" LDL's! 🙂
    I've already ordered the book Thomas recommended! 😁

    • @beepbeepnj2658
      @beepbeepnj2658 3 месяца назад

      Lipoprotein(a) is not a genetic disorder or a problem, it is your genetics for a reason to make you live a long healthy life. "Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio.
      "Nonetheless, the apo(a) size distribution in centenarians did not entirely explain the high Lp(a) levels observed in this population. Factors other than apo(a) size, and which may be either genetic or environmental in nature, appear to contribute to the elevated plasma Lp(a) levels of our centenarian population. We conclude therefore that high plasma Lp(a) levels are compatible with longevity." 1998 article by J Thillet

  • @victorcs_
    @victorcs_ Месяц назад

    What could explain a doubling increasing in someone Lp(a), with a LDL lesa than 60mg/dl and apob less than 50mg/dl ?

  • @nelsonhoffman5922
    @nelsonhoffman5922 3 месяца назад +1

    I like Dayspring, but he OVER EXPLAINS everything. THis is a simple concept that he makes overly complicated. It's not just this, it's all of his mechanistic explanations.

  • @stevemc2626
    @stevemc2626 3 месяца назад

    I’m still waiting for clarification on the long version as to whether dayspring has conflicts of interest with pharma. This man pushes statins like no other. I probably would too if I was paid to sell them.

    • @danieljrgensen133
      @danieljrgensen133 3 месяца назад

      @@stevemc2626 Well, all statins, except for Livalo(pitava statin), has been off patent for quite some time now, so the original pharma companies behind the statins, don't make money on them anymore(of any significance), as 99.99% of all patients use the much cheaper generic versions of the statins available today! 😉
      So I don't think Dayspring has any personal financial gain, by stating low LDL numbers should be a goal, if you care about maximizing your potential for living a long life free from sickness.
      How low the ideal LDL concentration in plasma should be, is perhaps still up for debate. But current data seems to suggest, you ideally want to be below 55 mg/dl.

    • @gregsilva7271
      @gregsilva7271 3 месяца назад

      And yet he states he doesn’t use statins, but rather, other cholesterol therapy…so your assertion may well be amiss

    • @stevemc2626
      @stevemc2626 3 месяца назад

      @@gregsilva7271 yeah maybe, but why won’t anyone involved with running this channel put it to bed with a statement that he doesn’t receive pharma money?