Lipoprotein(a): Who's Most at Risk
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- Опубликовано: 29 сен 2024
- Stanford Univerisity's Dr. Khandelwal and Family Heart Chief Medical Officer Dr. Mary McGowan outline who should have their Lp(a) tested and what to do with those results. #KnowLpa
Lp(a) is a risk factor, not an absolute sentence to cardiovascular disease. My doctor says "80% of CVD is environmental." So, as the video says, don't smoke, avoid obesity and diabetes, don't eat junk food, exercise, etc. Plenty of people with high Lp(a) values (which supposedly is inherited in a co-dominant fashion) never develop CVD nor have their parents and other close relatives.
Are you busy
What's the evidence for this statement: "Plenty of people with high Lp(a) values (which supposedly is inherited in a co-dominant fashion) never develop CVD nor have their parents and other close relatives."
Plenty? Quantify that description, please.
@@JaySeitzPhD "Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio.
As someone with High Lp(a), this was the best source of info on the topic I have seen. Thank you for a great presentation
If PCSK9 inhibitors are not FDA approved for LP(a) reduction, does that mean a physician cannot prescribe it off label? And will the pharmacy plan be less likely to pay for this more expensive drug being it is not FDA approved for that usage?
I was to be in a trial to reduce LPa (mine was in the 245 range). The followup prior to be in the trial my LPa was at 150 which was to low to be in trial. The only thing that changed was I was put on Repatha maybe 3 weeks before the followup. 150 is still high but it's been in that 240..250 range for about 10 years.
HI, are your numbers in mgs/dl or in nmols/liter?
After six weeks of 2000 mg per day Niacin treatment my Lp a dropped from 147 nmol/l to 45. I begun another six week 1000 mg Niacin treatment.
How you feel yourself using 2000 niacin?
Little sweat at night, somethimes
@@inaratolocko5723 very well. I should have new blood test results this week. I highly recommend Niacin, inexpensive and very effective
And again after six weeks of 2000mg Niacin per day result: 48 nmol/L
My new result is 48nmoll/l. Ecellent!
Thank you for the webinar. I shared it in my lpa/ heart attack Facebook groups
Yes, statins increase lip (a) significantly for people with genetic abnormalities, for example - family hipercholesterinemy
I have high LP(a) for many years. I'm 64 and my CAC is 32. I keep low carb/sugar, intermittent fasting paleo/keto eating lifestyle. Low inflammation and healthy blood pressure is the key.
@@Tendertroll1 LDL is 221 and Triglycerides is 101. HDL is 103.
Dr. Khandelwal, are you familiar with the Lp(a) work done by interventional cardiologist, Dr. Nadir Ali, from Webster, Texas? Dr. Nadir Ali not only opines that Lp(a) has NOTHING/ZERO to do with CAUSING atherosclerotic diesase (CAD, CVD), but he describes Lp(a) as a very important molecule in the repair process of damaged tissue. Dr. Ali describes some elderly patients, with lifelong high Lp(a) levels, who he has performed coronary angiograms on, and these patients have absolutely NO plaque whatsoever.
My father,his 3 sisters and a brother all passed away av a kind of fast and powerful heart attack at their late 50s. All their children have extremely elevated LPa. Mine alon is 469 nmol/l. So, your Doctor probably has done his research on wrong people.
Das wäre großartig. Ich habe im April Herz Ct mit Kontrastmittel. Ich bete,dass ich keinen Plaque habe 🙏🙏Danke für das Video
My LPa is 114, and I was told by BHF that in there opinion up to 300 is not considered extremely high and enough to impact on coronary health.
But over 300 should be managed by lowering LDL to help stop the LPa being able to stop it travelling round the body.
If its so important why isn't this test being carried out on everyone who has the cholesterol test.
@@quality6823hi
the overwhelming data shows he is wrong then. High levels of LPa can be easily tracked to a higher percentage of CVD and mortality.
I'm guessing he is one of these populist YT doctors who encourage you to stuff your face with red meat.
If you have high LPa and you are metabolic healthy (low carb) and you do not smoke then you enjoy the highest protection from living to a very old age BUT IF YOU NOT HEALTHY AND YOU ARE INSULINE RESISTENT AND YOU SMOKE THEN YOU HAVE THE HIGHEST RISK TO DIE EARLY
Per Linus Pauling and Mathias Rath, LP(a) is a marker for scurvy (vitamin c deficiency) in the arteries. I reduced my LP(a) almost in half with high dose ascorbic Acid.
@jeffm.8134! Thank -- you -- which high dosage, please?
@@ukispargitus970 I was taking 20g per day. I mixed it in my water and sip throughout the day. Linus Pauling was taking 18g. I now take 25 - 30g daily. Apparently I need a lot. Research vitamin dosage up to bowel tolerance.
My doctors refused to test.
Crazy. My GP tested without me asking/knowing what it was 🤷
Find another doctor.
After rosuvastatin I have lip (a) 517. I will try PCSK9 inhib.
I just found out mine is 486nmol/L after 4 years on a statin and then went off of it. I wish I had measured it before the statin
Hi
There are some old studies showing that androgens (testosterone, anabolic steroid) lower lp(a) by 60-80%. People who take testosterone replacement or anabolic steroids could be benefiting from it. Has anyone studied this?
I can tell you it didn't lower mine..I've been on TRT for a year and LPa is about the same.
I have it -- it is over 1500 so I am doomed sadly - live life
How much ldl
How much ldl
How much ldl
Hello how are you
Thanks for your presentation. As far as LP(a) levels it seem that the measured levels can differ when considering either mg/dl or nmol/L, they appear not to be interchangeable although 2.5 is being used as a converting number. Any comment on that? Thanks again
If the mean mw of two specimens is substantially different then the ratio would be different.
Excellent presentation. Very informative.
What role does ethnicity play in disease risk? Are elevated LP(a) levels as relevant for African Americans, as the Caucasian population?
Sadly, it is higher for Africans. Go to 10:26.
Can it cause pulmonary embolism in lungs?
Best treatment for atherosclerosis: Vitamin C
Why do only coronary arteries clog with cholesterol and not veins or small capillaries?
Scurvy = No vitamin C in your diet.
Symptom: Your blood vessels break and you bleed to death. Think of the sailor of the past.
Scurvy of the heart = Just enough vitamin C from food.
Symptom: Arteries around the heart are not strong enough to resist high blood pressure. Damage is repaired with cholesterol LP(a) to prevent worse. After years of repair, your arteries become clogged.
Enough vitamin C supplement of at least 3000 mg. per day gives strong and flexible arteries. Cholesterol is not needed as a repair agent. Cholesterol in your coronary arteries is broken down and burned in your liver.
Source RUclips: Cardiovascular disease and vitamin C (Dr. Rath Foundation)
or
Breakthrough Towards The Natural Control Of Cardiovascular Disease - Dr. Rath's 2018 Cyprus Lecture
Wrong Vitamin C oxidizes
A case study in the confusion of correlation versus causation