Видео

How soon will they possibly be available for patients? Some of us need it now and by then it may be too late. 😢

This is great! All my unanswered questions answered!

We’re doomed, basically. I had a heart attack in 2019 at age 46, family history. Finally had the lp (a) test and mine is very high, 308 nmol/L. It was probably high my entire life, but I’ll never know. I did find out that the level increases after a heart attack. It may have something to do with the wound healing intrinsic property of the lipo protein.

Thank you for so much information

If you measure it “at least once” you will not notice how wildly Lp(a) actually fluctuates…

The more I know about the Lp(a), the more I think it’s a B.S. - they did not even standardize how it’s measured and depending what antibodies are used to test it can give you higher or lower value… this comes across when the same individual measures it multiple times and you find that it actually fluctuates wildly - like, for example, 118 nmol/l to 190 nmol/l - and this is for something that supposed to be genetically determined and that’s argued that it’s “the same number” your entire life… very suspect!

I have normal LPa 48 but high ApoB 134. Which one would help my heart or kill me?

Once again, an oversimplification of LDL. There is ZERO evidence that high LDL-C is CAUSAL of heart disease. It is the sub-particle examination which is necessary. Meanwhile, statins are CAUSAL if insulin resistance, pre-diabetes, and Type 2 diabetes. These are CAUSAL factors of heart disease.

Thanks for sharing, Brian. Could you tell us what was the LDL goal (number) your cardiologists have now set for you?

Jennifer....your story is so inspiring. Very glad I got to know you!

Thank you for this. I have had 4 different LP(a) readings over 2 years. All high and fluctuating between 135 and 199 nmol/L. Took a PCSK9 for a year and my LP(a) actually increased while on the drug. So much we still do not understand. Hope the new drug treatments come soon and can be effective. In the meantime, control every other risk factor best you can.

Why did you not consider showing data results in mg/dl as well? Since this is the most common way of reporting in the U.S..

I wish the camera had a better focus and lineup with the chart data.

Dr. Baum, could you please cite ANY research/data that actually PROVES ANY CAUSE AND EFFECT between elevated Lp(a) and atherosclerosis. I don't seem to be able to find ANY literature on this topic, other than a bunch of very flawed associational stuff.

Why don't you respond to Nick Norwitz PhD? You are one of the most self-obsessed, arrogant, supercilious physicians I have ever seen. William Cromwell MD and Nick Norwitz will put you to shame. The biggest risk factor for developing coronary artery disease is Insulin Resistance / Hyperinsulinemia. LDL is largely irrelevant if one has a high HDL and Low Triglycerides with the ratio preferably being greater than one. How many shares of Big Pharma stock do you own? I am a retired physician.

Genes 😢

Check with the doctor? You have good sense of humour

how much aspirin was taken, how much per week ?

Marcus Flores from MALTA

Why would you say have LP(a) tested only once & it is stable throughout life when what I understand is that many factors raise and lower it?

Would a natto kinase supplement be recommended?

Do your research on statins , you’ll be very surprised when you dig deep into the adverse effects and misleading statistics on the outcome for health and longevity

I’m confused because I have lower numbers of apo (a) but elevated Lpa

I can't reach my LDL goals on statins and I want to get my hands on PCSK9 inhibitors. It's unfortunately hard to get that covered for primary prevention here..

Do people in Minnesota have lower LDL? That State has the lowest death rates from heart disease. What about LDL in Oklahoma which currently has the highest death rates?

If PCSK9 inhibitors are not FDA approved for LP(a) reduction, does that mean a physician cannot prescribe it off label? And will the pharmacy plan be less likely to pay for this more expensive drug being it is not FDA approved for that usage?

Thanks for posting these videos. It is a very helpful alternative for those of who were unable to attend but are keenly interested in FH Foundation's important work.

I would have preferred to see a recommended level of LDL cholesterol rather than vague generalities.

Care navigation. Another icky, Orwellian medical term.

Genes.

Re patient compliance: I am prescribed Repatha and am looking forward to discussing discontinuing it with my Cardiologist next week. Untreated avg LDL 170, with Repatha avg LDL 60. Repatha causes PVCs, so taking beta blocker fixes that. These are recent adds, already was on calcium channel blocker, diuretic and ace inhibitor for long term high bp. It has been too long, I don’t remember what my untreated bp was. No statins (tried 5) as they increase frequency of epileptic seizures. 68 yrs old male, 155 lbs. Avg treated bp 112/72, resting hr 56. (No cardio exercise, since adding Repatha and beta blocker I can no longer muster up the energy to get on my treadmill) Since adding the Repatha and beta blocker I have constant headache, brain fog, lethargy, and spend most of my days sleeping. I have a list of books on my reading list but concentrating enough to read is now too much of an effort. I want my life back, even if it is shorter than it could be, that will be much better than existing a few extra years as a zombie. Risks understood, rewards not worth it IMHO.

I find that lipidologists do not give PCSK9 inhibitors enough credit for lowering LP(a) levels. 20 to 30% is nothing to sneeze at. And although no definitive proof of the efficacy of such a reduction, it is reasonable to assume it helps some.

It's also not a disease. The average lifespan of people with FH is actually higher than those without. Cholesterol is good for you - that's why your body makes lots of it.

It’s past March but curious. I have an LPa of 102 Nmole/liter. It makes sense to me to help lower by either donated whole blood every 2 months or donating double platelets/plasma could help. Thoughts and reasons why/why not it would not work. Thank you!

FH is a buzz term: its a fabrication, and its nonsense. You MUST act, and the act you must undertake is in the immediate dismissal of that incompetent GP. Eat a species appropriate diet to satiety

Per Linus Pauling and Mathias Rath, LP(a) is a marker for scurvy (vitamin c deficiency) in the arteries. I reduced my LP(a) almost in half with high dose ascorbic Acid.

If you have high LPa and you are metabolic healthy (low carb) and you do not smoke then you enjoy the highest protection from living to a very old age BUT IF YOU NOT HEALTHY AND YOU ARE INSULINE RESISTENT AND YOU SMOKE THEN YOU HAVE THE HIGHEST RISK TO DIE EARLY

Yes!!! Fh in the family. But also alcoholaddicted. 😅

I have a calcium score of 900 - High level of Lp(a) 180 - and Coronary artery disease in 5 arteries including the LAD. I've been told that I will probably need a stent or bypass in the next few years (if I make it that far). LPa alone is not a major issue If you can reduce other risk factors. I am healthy weight, 56M, walk an hour a day and am on the Esselstyn diet. My LDL is down from 3.5 to 0.8 - I am working with what I can, I'm trying not to stress & that's all I can do, and I hope that you do the same.

Thank you for this valuable information.

A case study in the confusion of correlation versus causation

Probably black Americans and Hispanics

I can confirm that I have an LP(a) value of 109 nmol/L without a statin and LP(a) of 192 nmol/L on 40 mg Rosuvastatin. Same units!

Thank you.appreciate all the information

I am 22 years old. I am diagnosed with LDL of 329. So i have started taking high intensity statins and my ldl reduced to 170 in 15 days. So is it possible to predict that what type of FH i have? I have hearts tests done and they were normal

My doctors refused to test.

I didn't realise this was a bullshit cholesterol lie!

Is the heart foundation looking into the effect of covid vaccine? If not then it's shameful!

Excellent presentation. Very informative.

I have reversed my LPa with Magnesium Glycinate and Liposomal Vitamin C at 10 grams