Medical School - Glycolysis Made Easy
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- Опубликовано: 6 сен 2024
- In today's video we discuss the steps of glycolysis. We take glycolysis step by step so you gain a true understanding and minimize the need for pure memorization. Remember to watch our other videos to help you understand important concepts that you will encounter in nursing school, medical school, and physician assistant school.
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iMedicalSchool is a channel dedicated to helping you understand complex medical topics in a simple manner. We want to make sure that you understand every topic presented. We are happy to answer questions and take suggestions. No matter if you are in medical school, nursing school or physician assistant school we are here to help you learn more.
At first I thought he was talking wayyy too slow, but then ... it allowed me to think about what he was talking about. OMG THIS VIDEO IS DA BOMB DOT COM PLS
I learned more from this video than 4 lectures at University that I'm paying thousands of bucks for.. thank you thank you thank you
Simple clue, ALL kinases involved in glycolysis involve ATP (Hexokinase/glucokinase, PFK-1, phosphoglycerate kinase, pyruvate kinase), and ALL dehydrogenases reduce/oxidize NAD+ to NADH (glyceraldehyde 3-P dehydrogenase, Lactate dehydrogenase for anaerobic).
1. ALL kinases in glycolysis use ATP
2. ALL dehydrogenases involve NAD
That is only good until pyruvate, once pyruvate enters the mitochondria, it gets slightly different (pyruvate carboxylase uses ATP) but it's a quick way to remember (hope it helps)
+Sean Chagani You are amazing, you just made this much easier to remember for me!
😊 good....
But ATP is also consumed when kinases act in some steps...right?
I mean ADP
Guys wish me luck tomorrow is my Carbohydrates biochemistry test!!!
Dave James Good luck bro!
good luck DJ!!!!
@@MrPridizzle lol
Gl Dave
i was so confused in class when my professor when over glycolysis which took all of 2 50min lectures this 11min video just created a new synapse and glycolysis will forever stay with me... thank you so much for providing this video... best video I've seen thus far!!!
I'm laughing in sadness because I don't know where this video was when I was studying for my last biochem exam where I literally did the ini-mini-myni-mo game. hahaha T---T
i feel ya....
That was just a well taught and presented video. It was the perfect video, at the level needed, to not have to study anything else but your video to cover the glycolysis portion of my test tomorrow. Great job. Hoping you have a Krebs video.
in 9th grade honors biology were learning cellular respiration. We don't go in depth into how or why everything happens to the atomic level, although that is the only way to truly understand it. Instead we are only taught the major things that happen, like Glucose takes 2 atp and becomes two pyruvate molecules, producing 4 Atp. This video helps to understand how everything happens.
in the US, it doesn't advance much, until you reach higher level college courses. I'm just now required to know each step. even in general biology, it was simplified to not much more than you mention.
Random Internet Profile Last year when I posted this comment I was in honors biology. I live in the US too.
I am taking biochemistry as an undergraduate summer course. My professor, while smart, seems to have spent too long researching and not enough time teaching. Confusing!
This video unraveled in 11 minutes what he spent a week running circles around me with. Perfect way to actually understand this material instead of base memorization.
Thank you so much for making it!
Great video, the only you might want to mention somewhere is that only 3 of the steps are irreversible:
-Glucose -> Glucose-6-Phosphate (rate limiting step)
-Fructose-6-Phosphate -> Fructse-1,6-Bisphosphate (most important step)
-Phosphyoenolpyruvate -> Pyruvate (substarte-level phosphorylation)
Great video and definitely worth the watch. Thanks!
I love you so much. I am taking cell biology and this was not broken down this well.
haha nice pun
This is possibly the best glycolysis video on RUclips!
In my opinion this is the best glycolysis video online.
I've been trying to understand glycolysis and the role of ATP for 3 years and just learned it in 11 minutes.... amazing video, thank you!!!!
thank you medical school it helps me to understand glycolysis cycle....because so many times i tried to by heart this cycle but i never remembered....but after watching your video it help me out....to understand this cycle....:)
Thank you so much sir. You are my invisible teacher, next to my parents.
I'm here because my professor failed to do his job... Thanks a million!
This was the BEST video that I found on glycolysis. I really appreciate the direct information of this video, and its step by step break-down.
This is exactly the level of depth necessary for me to study for my molecular bio exam next week. So glad I found this video, and thank you!
fantastic video, got a test tomorrow on this tomorrow and I didn't have a clue about anything on glycolysis but I have a good understanding after watching this.
What. the. hell. ...I refuse to let this deter me away from my dream job though!!!
OMG THANK YOU SO MUCH FOR THIS VIDEO. My bio midterm is tomorrow and I have to write about the enzymes of glycolysis. You're a life saver.
Ummm.... If this is to be taught in medical school why is this in my 11 th grade bio portions ?
hii
You will not need to know it in the same level of detail
Actually we did ... Hi Anil ! ;)
This a dumb down version of glycolysis. In medical school you will learn all the pathologies involved.
Glycolysis is taught in high school but in medical school you discuss glycolysis in terms of diseases and how defects in the cycle relate. Thanks for watching!
Thank you so much my teachers are terrible at explaining my lecture to be honest you saved me a lot if time.
This is by far the best video I have seen and I plan to watch it a hundred times. Thank you for the help!
I was studying for a test and this really helped me better understand glycolysis. This was actually the essay question and now after watching this video, I feel I am more prepared for my test. Thank you! :)
Only request: Could you show the whole cycle in one picture after pyruvate is formed? This helped a lot thank you!
Thank you very much, studying for a test about gycolysis and citric acid cycle. This really helped. Now to see if there's a good CAcycle video
Hi I'm a 1st yr med student in Craiova/Romania and I gotta say YOU ARE AWESOME
and i am a ex student of constanta howis in romania now?
well it's pretty good .When did you graduate?I'm in the English section.I heard Constata is a good uni but the city is a little expensive coz its near the sea ,esp. in summer.
Great video, current MS 1, works really well if you draw along with the video and follow with your own notes from lecture
Brain just fucking exploded.
This is so awesome! It is my first year in medschool and I needed simple explanations SO BADLY! And then I watched your videos. Funny thing is,even though I'm in college in France (so I guess our systems are quite different from each other), they are still very helpful! so THANK YOU! Really!
How is medical school so far? I'm in my last year of high school and I'm considering becoming a physician but I'm horrible at biology. What degree did you get because you started medical school?
+sydney yendys if the school doesn't offer premed then usually biological science or similar majors will be fine. Just make sure to take all the required classes.
Really like the way glycolysis was explained in a words that helped me understand this process a lot better. Can't wait to see all the other videos you produce/are producing on the various metabolic processes.
Many thanks. I might actually pass my Chem exam next Tuesday!
Viv :-)
Words cannot express how greatly this video has saved my Grade 10 Biology mark.
Just kidding I got a B- on the exam anyways *cries*
Now I've downgraded to AP and this video is going to save me again
after 3 days i have cabohydrate metabolism test....nd thnk GOD i got this video...
This is the best video of glycolysis I've seen on the net!!!!
Thank u....tmrw my bio chem exam... it is usefull completed in 10 mins...... thank u
Thank you so much for making this video. A valuable resource for nursing students as well.
This makes more sense than the lecture does!!! Love it man... Keep them coming!!!
Thanks for the video. I'm taking physiology and this video is super helpful for understanding the basic steps of glycolysis.
Love the explanation, great speed and very understandable...makes much more sense.
The best video about glycolysis I’ve ever seen
I guess a lot of people already thank you for that but Man!! I'm in the first year of med school (in France, even tho how program might be completely different we still have the same basis) also and this helped me a lot just to see how does it works, what each molecules require to work. Thanks :)
I aint gonna forget it: a Kinase enzymes infers the moving of an inorganic phosphate. :)
+Ritchy Emboulé our*
This is so helpful. Way better than the breezy metaphors my prof tried to use. Thank you!!
it is really helpful. i've been studying glycolysis from the past 3 months. but didnt had clear idea, but this video helped me a lot especially in remebering the enzymes and their concerned step. :)
The 6th carbon on the glucose-6-phosphate is missing an oxygen. It should be "CH2OPO3^2-" instead of "CH2PO3^2-". Great video, though!
+Shane Cronin Thank you, I was wondering why the number of Oxygens was changing when it was isomerized to F-6-P
You are the shit :D I don't get why lecturers make it unnecessarily complicated. This video is amazing. Thanks :)
This is the best explanation I have seen so far.
The first release of water isn’t in the enolase step. Note that in the aldolase step, an acid in the active site and a free-flowing H+ ion interact with the carbonyl to produce a water. While it is quickly recycled and used to convert DHAP to G3P under a majority of physiologic conditions, a water is still synthesized, potentially remaining as such until Le Chatelier’s principle necessitates the isomerization.
Beyond that, the rest of the video is great!
This is beautiful. You saved my life. God bless.
That was absolutely extraordinary presentation about Glycolysis . Much Much appreciated.
Thanks for the great video! This is much better explained than the hideous diagram by my textbook lol.
This is great!! But there are 10 steps and you have 9. You combined steps 4&5 into step 4 so it kind of throws some things off. Step 5 is where DHAP gets acted on by triose phosphate isomerase to produce glyceraldehyde-3-phosphate. Steps 6-10 are supposed to be energy producing steps that double their products. That was a little unclear here. But this is pretty great. Thank you!
That's so much easier to understand how my lecturer just described it! Thank you :)
soooo helpful! Followed my textbook as you spoke and you didn't miss a thing! Thanks a lot!
Thank you. I finally understand glycolysis properly.
It would be great if you could zoom out so we could see the whole diagram and all the steps next to each other. But great video!!
Amazing video. Keep it up and thank you. Very good for refreshing your memory.
Regards, 2nd year MD.
This video is amazing!! You explain it so simply and clearly. Thank you!
You guys had my subscription as soon as the first song started lol.
Not a bad presentation. It's pretty clean, and I'm sure it has helped a ton of people with the concepts.
I think it would have been nice to see a mention of the glycogen phosphorylase step that occurs when the source is coming directly from glycogen instead of free glucose. This step bypasses the hexokinase step and as such skips the first ATP investment.
Under higher intensity scenarios, phosphorylase activity increases, and I would argue that more glycolysis is resulting from a glycogen source instead of free glucose. That said, all of the steps afterward are explained rather well, and I don't want to take away from that. Please continue the good work :)
[My Background -- Exercise Physiology grad student and metabolism junkie]
Clear, concise video that helped me understand Glycolysis.
Simple and straight forward explanation..thanks Doc.
This is better than my lecture section
This is great! The layout of your videos is awesome - a more detailed description followed by a brief synopsis with the important points highlighted. Thank you thank you!
Biochem test tomorrow. This helps a ton!!!
Pedagogy at its finest - bravo.
Thank you so much, it helps me alot to understand. and that key points were really nice.
YOU SAVED MY EXISTENCE!
This is the most helpful glycolysis video out there. Thanks!
you are a savior....Thanks alot, you just made my life better.
I think there was a small error at 9:09 - The oxygen that is single bonded to the second carbon on pyruvate should sport a negative charge.
Other than that, I think this a wonderful video for Glycolysis. It's clean-cut, organized, and really breaks it down!
I was talking about NADH formed during glycolysis. Like how these reduced molecules are important. Pyruvate is the main product but he should also say NADH's job too. It'll be easy to follow.
you are seriously the best! thank you! :D and thank you RUclips! :D
Great video!! I'm about to start medical school and this helps a lot. THANKS!!!
this is one heck of an amazing video! my gosh thank you so much. solves much of my problems. keep uploading. God bless. thanks, mann!
I love this!!!!!! keep it up; really broke it down for me and made me understand! :)
i really loved this one .......clear and precise
BEST GLYCOLYSIS VIDEO EVER
Wow perfect explanation!!!👍🏻👏
You have no idea how much you have helped me!
this was so simple and easy to understand. amazing, thank you!
thank you for explaining sooo well... im getting a head start for my metabolism class.. this video sure helped :)
Thankyou this was so helpful for my Clinical life science Biochemistry !!
This was EXTREMELY helpful! Thank you!
i would be dead without you
awesome , hope i will remember it in my test next saturday
Excellent video! This is going to help me so much on my exam lol. Thanks a million!
Thank you so much! You're much better than my prof.
A lot of info but super easy to follow!
Best video ever. Thanks a lot!
This video is a life saver!! The material is well explained and presented, thank you so much;-)
OH MY GOD!!! THANK YOU (subbed)
IVE BEEN SEARCHING FOR SOMETHIMG LIKE THIS FOR LIKE 2 HOURS
TEST TOMORROW 😥😥😥😥😥😥
Really interesting n educative video, dis really makes glycolysis easier to commit to memory.
Thanks so much
The two G3P compounds only have 5 H, right? Then how is it that 2NADH and 2 H+ come from the production of 1,3BPG, which each have 4 H???
Thank you so much! This was incredibly easy to follow and extremely helpful!
This video was extremely helpful.
I thought khan was the best, until now! Thanks for making bio chemistry relaxing =) Keep it up man!!!!
THANKYOU SO MUCH THIS HAS SAVED ME
This is amazing way to teach. Thank you for your work