@@geolinotag9502 No, it is not a cure. It is a highly effective treatment and pre-exposure prevention measure. It will keep people from going to full blown AIDS and dying. Quality of life improvements, etc. I think that is what the OP was referring to. Nobody has this confused with an actual cure, if we manage to ever find one. The "cure" will be a vaccine, given at birth to everyone. Like what is done with Polio and used to be done with Small Pox.
@@chimdi_samuel The Trial was conducted in Gilead Science South Africa so there are the one who collected all the Data ofcourse with the help of Uganda
This is still in early development, in regard to its application as a PrEP medication. The current price at around 40000$ reflect the cost of its initial setup and clinical trials. Analysts expect that the consumer price will be around 40$ (with a margin of 30%) when they reach 10 million consumers annually. (Economics of scale is everything) Let’s be hopeful✨
I doubt it will happen. Any chemist in the pharma industry that looks at the API can tell that it would cost between $2,000 to $3,000 a kilogram to produce this molecule at scale: 10 to 20 t annually. If it really is a twice yearly injectable with a very low dose, under 50 mg, maybe $40 to $50 a year is achievable, but it’s more than likely going to be over $100. Gilead already grants licenses to generic manufacturers to produce HIV related drugs for emerging markets. The details aren’t published, but it’s widely known that the licensing is royalty free with the agreement not to ship or sell into Europe or North America. Pharmaceutical companies are for-profit entities, not charities, and it’s critical to keep this point in mind. The main, practical reason is not drugs that are currently on the market, but the research, ongoing research that will lead to cure. A cure is imminent. The mechanism of action of this drug, Lenacapavir, is really intriguing. There’s a rush of research right now into capsid inhibitors. Just like what happened for hepatitis C, more drugs will come to the market very soon. It’s critical not to discourage pharmaceutical companies from doing research into HIV. In fact, with the exception of Gilead, most major pharmaceutical companies have got out of the viral infection market! That is bad. Anyway, HIV will soon be a thing of the past. One passing thought, it behooves countries in Europe and North America to subsidize the distribution and the use of these drugs in developing economies. There are really practical reasons for getting rid of the scourge of HIV it to everyone’s advantage that this virus be relegated to the history books . Subsidizing means not only production of the drug, but the distribution and maybe even provision of financial incentives for people to use it. Compliance is probably the last and toughest barrier to breach.
We hear this and similar breakthrough all the time. We never hear of them again and they never hit the market. I will believe it when I see it in the market.
Ask African leaders to make it so that we have pharmaceutical companies that can discover such drugs. We can't blame a foreign business for wanting to make profit and not being able to work out favorable conditions to make profits here in Africa. Africa cannot take care of itself, always relying on foreigners to do so, and wonder why we are poor and worse off! A drug that costs $40,000 year will be difficult to be made cheap for Africa, unless they dash it out. Gilead is a business, not a non-profit organization. Africa likes good things but never willing to pay the price for it! Stop selling your votes! Not talking to you specifically, I'm just saying!
It’s already on the market in the USA. HIV+ people can get the shot twice a year. They even mentioned that in the report. It’s been available since 2022. What they are trying to do is get the shot more widely available for poor people in Africa
I've lost countless friends to HIV/AIDS, men and women from all backgrounds. Although medication exists, and there are many examples of people living with HIV still live today because of the medication, it still feels incredibly hard to persuade people to even take the test. I volunteered with a government HIV prevention program for two years, but eventually, I stopped because I could no longer bear seeing people die from HIV.
The company probably spent tens of millions of dollars to develop this drug, and hundreds of millions of dollars to develop a bunch of comparable drugs that failed. They can't just sell their successes at production cost and expect to stay in business to develop tomorrow's drugs. If this is going to be cheap and available then governments have to step in and fund it, like they did with COVID vaccines. That said, it sounds like the company is considering an equitable pricing structure: selling it cheap to countries that would never cover the development costs anyway, so there's nothing to gain by withholding it.
That company may have received research grants, government funding or grants from foundations to develop this drug. In that case its profits can’t be claimed to be their exclusive investment.
😂😂😂 It is be $100000 USD. American pharmaceutical industry will never give up patents or share with other countries. They'll first reap the profits for 20 to 30 years or until a competitor emerge with their own drug.
People need to take responsibility for their own lives. We’ve had oral PrEP for years now. You just need to take it every day. There is already solution which costs around $60 dollars per month (for the generic pill). $720 dollars per year to end hiv. Do people listen, do they take responsibility? Society is so infantilised. If you don’t take responsibility for your own life and actions, you get what you deserve, and society should not have to pay for it. $40000 per year. Ridiculous.
How much government funding or grants from foundations have helped this manufacturer to invent this drug? If this is true then profits need to reflect that.
2 jabs per year is the best solution for AID protection but generic drug must be necessary in this case because original cost of this med is so EXPENSIVE.
If I look at the price and the fact that this is just for prevention(of which there are pills) why won't I think these pharma companies are just after our monies. If it was a cure at that price, why not? But prevention? When there are already pills for that ?
PreExposure prophylaxis is already given commonly to people who are at risk (spouse, sex worker, etc) But it's given as pill and must be taken everyday It's effective if given at least 2 weeks before and 2 weeks after risky activities
If you listened carefully to the report, the issue is that people don’t take pills consistently and thus the virus continues to spread. Scientists are hoping that a long lasting shot can essentially work like a vaccine…to prevent infections
Ask African leaders to make it so that we have pharmaceutical companies that can discover such drugs. We can't blame a foreign business for wanting to make profit and not being able to work out favorable conditions to make profits here in Africa. Africa cannot take care of itself, always relying on foreigners to do so, and wonder why we are poor and worse off! A drug that costs $40,000 year will be difficult to be made cheap for Africa, unless they dash it out. Gilead is a business, not a non-profit organization. Africa likes good things but never willing to pay the price for it! Stop selling your votes during elections! Why do we always beg? Disappoint and depressing! 😢😢😢
Those who want it now will pay top dollar. As with all things, the price will go down eventually for the majority in due time. And or a cheaper version will hit the market.
Like everything, it will come down. If not now, then down the line. In the meantime medication patents in India are breached always (I think even by law) so they will probably make cheap versions for the 3rd world.
Bro…did you listen to the report ? There’s a huge difference between a daily pill that people skip too frequently and a shot that only needs to be given 2x per year
@@kingmaafa120Sub Sahara has the highest rates in the world, therefore test it in the population that is most likely to be exposed, Mbeki made it so much worse not to mention government lack of free condoms
@@cyantwo936They do - just read the instructions with any drug you are prescribed. You can also use the reporting system to tell them of your experience.
Thank you for replying to this comment. So God created it and decided to kill it now, and yaayyyy thank God??? You should review your religious mentality. If it makes sense or not. It's also nice to review the history of it.
@@ericosa7002The price is rediculous first an foremost and secondly this means a person would spend $40,000 for 2 shots, thirdly this isnt even a cure for such a price they could have made a cure rather or made this affordable since it isnt a cure.
can you put someone with neutral accent to read news, so that we all can understand please? i dont understand his accent. do not put someone just because of color, greetings from latam, thx
Bacterial STDs like syphillis can be cured with a shot. You can even diminish your chances of catching bacterial STDs by using DoxyPrep, not to mention the usual things like condoms, etc
I have lost friends in the early 2000s in the Philippines due to HIV. I wish they lived to see this happen.
I am sorry for your losses.
It is a preventive drugs not cure dude
@@geolinotag9502 No, it is not a cure. It is a highly effective treatment and pre-exposure prevention measure. It will keep people from going to full blown AIDS and dying. Quality of life improvements, etc. I think that is what the OP was referring to. Nobody has this confused with an actual cure, if we manage to ever find one. The "cure" will be a vaccine, given at birth to everyone. Like what is done with Polio and used to be done with Small Pox.
Our South African scientists 👏🏾👏🏾👏🏾🇿🇦
What did they do?
The drug is made by Gilead in the USA😂😂😂😂😂😂
@@justinmagagani8835 do you know Gilead Science have Branches outside USA?, Gilead Science South Africa is one of them.
@@chimdi_samuel The Trial was conducted in Gilead Science South Africa so there are the one who collected all the Data ofcourse with the help of Uganda
This is still in early development, in regard to its application as a PrEP medication. The current price at around 40000$ reflect the cost of its initial setup and clinical trials.
Analysts expect that the consumer price will be around 40$ (with a margin of 30%) when they reach 10 million consumers annually.
(Economics of scale is everything)
Let’s be hopeful✨
I doubt it will happen. Any chemist in the pharma industry that looks at the API can tell that it would cost between $2,000 to $3,000 a kilogram to produce this molecule at scale: 10 to 20 t annually. If it really is a twice yearly injectable with a very low dose, under 50 mg, maybe $40 to $50 a year is achievable, but it’s more than likely going to be over $100.
Gilead already grants licenses to generic manufacturers to produce HIV related drugs for emerging markets. The details aren’t published, but it’s widely known that the licensing is royalty free with the agreement not to ship or sell into Europe or North America.
Pharmaceutical companies are for-profit entities, not charities, and it’s critical to keep this point in mind. The main, practical reason is not drugs that are currently on the market, but the research, ongoing research that will lead to cure. A cure is imminent. The mechanism of action of this drug, Lenacapavir, is really intriguing. There’s a rush of research right now into capsid inhibitors. Just like what happened for hepatitis C, more drugs will come to the market very soon. It’s critical not to discourage pharmaceutical companies from doing research into HIV. In fact, with the exception of Gilead, most major pharmaceutical companies have got out of the viral infection market! That is bad. Anyway, HIV will soon be a thing of the past.
One passing thought, it behooves countries in Europe and North America to subsidize the distribution and the use of these drugs in developing economies. There are really practical reasons for getting rid of the scourge of HIV it to everyone’s advantage that this virus be relegated to the history books . Subsidizing means not only production of the drug, but the distribution and maybe even provision of financial incentives for people to use it. Compliance is probably the last and toughest barrier to breach.
I never thought I would live to see HIV treatment. Kudos to medical sciences!
Well Done Research Team! GG
I wish I have enough money to buy it for many poor people for free
I was hopeful until I heard the price
We hear this and similar breakthrough all the time. We never hear of them again and they never hit the market. I will believe it when I see it in the market.
Ask African leaders to make it so that we have pharmaceutical companies that can discover such drugs. We can't blame a foreign business for wanting to make profit and not being able to work out favorable conditions to make profits here in Africa. Africa cannot take care of itself, always relying on foreigners to do so, and wonder why we are poor and worse off! A drug that costs $40,000 year will be difficult to be made cheap for Africa, unless they dash it out. Gilead is a business, not a non-profit organization. Africa likes good things but never willing to pay the price for it! Stop selling your votes! Not talking to you specifically, I'm just saying!
It’s already on the market in the USA. HIV+ people can get the shot twice a year. They even mentioned that in the report. It’s been available since 2022. What they are trying to do is get the shot more widely available for poor people in Africa
I've lost countless friends to HIV/AIDS, men and women from all backgrounds. Although medication exists, and there are many examples of people living with HIV still live today because of the medication, it still feels incredibly hard to persuade people to even take the test. I volunteered with a government HIV prevention program for two years, but eventually, I stopped because I could no longer bear seeing people die from HIV.
20,000 a shot??? Why are we even talking about this
The company probably spent tens of millions of dollars to develop this drug, and hundreds of millions of dollars to develop a bunch of comparable drugs that failed. They can't just sell their successes at production cost and expect to stay in business to develop tomorrow's drugs. If this is going to be cheap and available then governments have to step in and fund it, like they did with COVID vaccines.
That said, it sounds like the company is considering an equitable pricing structure: selling it cheap to countries that would never cover the development costs anyway, so there's nothing to gain by withholding it.
That company may have received research grants, government funding or grants from foundations to develop this drug. In that case its profits can’t be claimed to be their exclusive investment.
That is a legitimate issue but some company will develop a generic version of it sooner and make it widely available.
@@cleanupkenya3915 Surely there is a patent which lasts for years before other companies can make a generic drug?
@@cleanupkenya3915not unless WHO intervenes , generics take twenty years to come into market due to patent issues
@@harperwelch5147 research grants for a lab virus..
$40 000 for two shots yearly is really indecent
So basically, one shot of this drug is like buying 25 iPhones every 6 months..
Is this injection made for those who are infected with this virus aswell ?
@@aakashthapa23946 Yeah that's the idea it seems....also may be used as a preventative drug....it's not a cure for HIV though!
Congratulations to South Africa and all world 🌍
Watch Gilead stock price skyrocket.
Well done South Africa.
What did ZA do?
40.000 a year just to prevent? Too expensive
How much do condoms cost?
$20,000 per shot!? LOL Why are we even discussing it?
😂😂😂😂
They have finally treament for this labvirus... be happy
Same as pills....
So millionaires will know
With my plan, it insurance reports paying circa $4500/month x12 = $54,000. That's more than $40,000.
Give it to India They can manufacture it cheaper
Yes we do 😁😉
They need to respect all those Doctors by showing their medical credentials (MD). This is totally disrepectful !!!
😂😂😂 It is be $100000 USD. American pharmaceutical industry will never give up patents or share with other countries. They'll first reap the profits for 20 to 30 years or until a competitor emerge with their own drug.
People need to take responsibility for their own lives. We’ve had oral PrEP for years now. You just need to take it every day. There is already solution which costs around $60 dollars per month (for the generic pill). $720 dollars per year to end hiv. Do people listen, do they take responsibility? Society is so infantilised. If you don’t take responsibility for your own life and actions, you get what you deserve, and society should not have to pay for it. $40000 per year. Ridiculous.
Cute is better than prep. People need a cure
1:34 what a lovely way to describe my laziness and procrastination when people ask me how I forget to take my own prescriptions haha
Well done! Huge round of applause to the researchers/scientists!
They want to create a product to consume not to cure.
Today I learned my face is more effective at preventing HIV infections than a $20,000 drug.
What do you mean ?
BEST COMMENT
We need the use of IAs specialized in health in order to avoid big companies getting monopoly of meds
Good one
The really wicked part is the price.
They've developed a drug to cure HIV/AIDS and they add an obsurd price tag, or any.
You do realize the amount that goes into research of a product is high
When will it be available?
It will come down for sure, but you mist protect your body for s meantime until it is accessible for mass population
How much government funding or grants from foundations have helped this manufacturer to invent this drug? If this is true then profits need to reflect that.
wow this is amazing
2 jabs per year is the best solution for AID protection but generic drug must be necessary in this case because original cost of this med is so EXPENSIVE.
If I look at the price and the fact that this is just for prevention(of which there are pills) why won't I think these pharma companies are just after our monies. If it was a cure at that price, why not?
But prevention? When there are already pills for that ?
Science Rocks! 🤘🏻🤘🏻
Yer right
Science introduced it then science attacked it
@@enosenos185 Correct, Science creates diseases...👍🏻👍🏻
@@enosenos185 Correct...
Science creates diseases...
👍👍
🙄
Not much more expensive than Cabenuva. Cabenuva lasts two months and costs about $6,000.
PreExposure prophylaxis is already given commonly to people who are at risk (spouse, sex worker, etc)
But it's given as pill and must be taken everyday
It's effective if given at least 2 weeks before and 2 weeks after risky activities
Let UNAIDS work with Gilead to bring this drug tomorrow. every week thousands of New HIV positive people are registered
The doctors making this drug can’t afford it
Its a game changer
@rockefeller1787 it's not, just extra marketing on things that already exist
The most amazing incredible patient intelligent kind inspiring person I've ever known has HIV & if I could I'd give my life for him to be free
PEP/PrEP is nothing new
Arv therapy scheduling is a new spin on the profit tho. Remember covid?😂
If you listened carefully to the report, the issue is that people don’t take pills consistently and thus the virus continues to spread. Scientists are hoping that a long lasting shot can essentially work like a vaccine…to prevent infections
Right nothing new because Gilead has been leading the world in research for decades!
Wow, I hope they can manage to lower the cost and really get it to purple who need it the most! Gilead likes big profit 😢
Sex education need to be taught as well for woman and men, gay and straight.
Good News
This guy being interviewed drives me crazy with the “ ahh “ ahh “ ahh mumbling
As long this isnt any cure people shouldnt gamble themselves into this scammers.
Ask African leaders to make it so that we have pharmaceutical companies that can discover such drugs. We can't blame a foreign business for wanting to make profit and not being able to work out favorable conditions to make profits here in Africa. Africa cannot take care of itself, always relying on foreigners to do so, and wonder why we are poor and worse off! A drug that costs $40,000 year will be difficult to be made cheap for Africa, unless they dash it out. Gilead is a business, not a non-profit organization. Africa likes good things but never willing to pay the price for it! Stop selling your votes during elections! Why do we always beg? Disappoint and depressing! 😢😢😢
Those who want it now will pay top dollar.
As with all things, the price will go down eventually for the majority in due time. And or a cheaper version will hit the market.
Medical science FTW 😊
It's available in india for only 799 US dollars per injection for Indians only
😂
Vaccines should be for free. The amount of billions that was donated for research
Lenacapavir is a major improvement but it's not a cure. Metformin and other drugs show great promise, more research and investment are needed.
Go South Africa 🇿🇦 🇿🇦🇿🇦🇿🇦🇿🇦
African solutions to African problems.. hats off to them 👏👏
So man will get ?
Seems obvious now, seemed unfathomable last week.
Isn’t that called prep?
Prep pill still the most used
$40k a year for the shot? Did I hear that right?
Like everything, it will come down. If not now, then down the line. In the meantime medication patents in India are breached always (I think even by law) so they will probably make cheap versions for the 3rd world.
@@snoomtreb I only wanted to be sure if I heard the amount right
No you did not. This product is not on the market. That price quoted was for the pills.
Do patients have to be knocked out in order to get theie injections.
As a Nigerian I'm so proud of these beautiful people🇿🇦🎉 🥰
Is it only business or promotion or in favour for humans because this is price is so higher than reasonable price
Didn't CRISPR DO THIS LIKE 5 YEARS?
I’d check that company 👍 🤐
Why is everyone pretending Truvada doesn't exist?
Bro…did you listen to the report ? There’s a huge difference between a daily pill that people skip too frequently and a shot that only needs to be given 2x per year
@@junsu21 why are YOU pretending Truvada doesn't exist?
It is a complete cure?
So who’s this really for 😮
Republican congressmen and donors
Wonderfool news !
Make a medicine that have to take once in a year. It would be more than enough.
A drug that works 100% and is FREE can someone tell me the answer..............
Yes the drug is called good decisions
Abstinence
for goodness sake just cure it already if u can prevent it you can cure it.
Under his eye
We need this for Covid next.
Research should done by AI like Russia so they could finish it quickly
It was tested on africans
How was it spread in Africa? Only southern and east Africans susceptible to HIV? Or they have very loose morals compared to others
Yep
Should have been tested in dem European bath houses and rave parties
@@kingmaafa120Sub Sahara has the highest rates in the world, therefore test it in the population that is most likely to be exposed, Mbeki made it so much worse not to mention government lack of free condoms
Why would you test that on countries that doesn't have HIV problem?
🤦🏻♂️… PreP pill is the easiest
Prayers failed for 100 yrs 😂😂😂
You sound like a weird dude. Next time, watch the video first, and then leave a comment.
The people who need it most would rather get the money this shot costs.
Damn science !! You are scary......👏
Ignorance is scarier.
99.99??
❤❤❤
Pre-exposure/post-exposure prophylaxis, this is nothing new
6 month injection is new
@willymuga1457 the side effects aren't, but they don't tell you about those
@@cyantwo936Says the School dropout 😂
@ratnamani8228 I do r&d for medical devices, I know too much about HIV specifically 🫣. Try projecting less
@@cyantwo936They do - just read the instructions with any drug you are prescribed. You can also use the reporting system to tell them of your experience.
40k yearly. Mf😅
China can make a cheaper one.
There's still hope for humanity. Thank God Almighty
Not god, thank the researchers and the investors.
Thank you for replying to this comment. So God created it and decided to kill it now, and yaayyyy thank God??? You should review your religious mentality. If it makes sense or not. It's also nice to review the history of it.
Way to ignore and erase the effort the researchers did
Big if true
Whoever created this disease made it v tricky to cure or... 🤔
What a poorly scripted interview with the last person sounding like a "spin" doctor whose words are lacking in efficacy itself!!!
I came to comment the same that ahh ahh ah mumbling had me crazy
These drug companies are evil.
Why do these companies evil ,give us an explanation
@@ericosa7002The price is rediculous first an foremost and secondly this means a person would spend $40,000 for 2 shots, thirdly this isnt even a cure for such a price they could have made a cure rather or made this affordable since it isnt a cure.
Science beach! 😂
The biggest joke is them pretending they only JUST discovered the cure 🤣
can you put someone with neutral accent to read news, so that we all can understand please? i dont understand his accent. do not put someone just because of color, greetings from latam, thx
Their are other stds like syphilis
Bacterial STDs like syphillis can be cured with a shot. You can even diminish your chances of catching bacterial STDs by using DoxyPrep, not to mention the usual things like condoms, etc
syphilis has a cure if caught early. Reminds me of that office episode where Michael raises money for a cure for rabies.
didn't know there that many flavors of men
I don't even understand what he meant there😅
I think this is who they’re 🎯
Everything about hiv prevention drugs is always in speculation never comes through
Facts
When aids cure will be come
I'm not convinced, interview someone who is HIV+ and is receiving tx.
You can Google and find stories of people using this treatment man
Side effects : Raccoon city 🧟♂️
Don't trust this channel
just say men and women🤣already
Alright. Now force the african countries to pay.