Hey^^ (2:50) None of the literature I've come across describes oxypurinol as an allosteric inhibitor (non competitive inhibitor). From what I've gathered, most likely, the allopurinol is transformed to oxypurinol, which reduces the active site of the xanthine oxydase. The oxypurinol then reorients itself in the active site to form a very powerful non-covalent bond with the reduced molybdenum. Since oxypurinol still acts in the active site, I don't think it qualifies for non-competitive inhibition. This channel helps me a lot, thank you for the videos ! (-;
Hey^^
(2:50) None of the literature I've come across describes oxypurinol as an allosteric inhibitor (non competitive inhibitor). From what I've gathered, most likely, the allopurinol is transformed to oxypurinol, which reduces the active site of the xanthine oxydase. The oxypurinol then reorients itself in the active site to form a very powerful non-covalent bond with the reduced molybdenum. Since oxypurinol still acts in the active site, I don't think it qualifies for non-competitive inhibition.
This channel helps me a lot, thank you for the videos ! (-;
I love this channel so much. It help me to understand. I hope there is more video from this channel. ❤
Hi! You may sign up for a free trial account at osmosis.org to access more! :)
ThankYou Best Teacher .
You're welcome! 🥰❤️🙏🏼
You make life easier
Thank you! 🙏🏼
So so so much...... Nice 😊😊 , educational and interesting 🎉
Glad you enjoyed it 💕
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Probenecid increases the duration of action of penicillin
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It can Prevent by intake of more water to realise and decrease down of uric acid in body
Is this benifical For gout ????
🎉🎉🎉
👍🏻👍🏻👍🏻
ohhhhhhh
But why there is no medicine which can totally cure this ?
Just like arthritis, it can only be managed. I think due to the nature of the human joints
@@chukwudi_valentine is there any reasearch ongoing regarding this
@@black_shadow_295can't say. Really
Medicine can’t cure everything yet! Most diseases can only be managed and not cured!
It can be prevented by reducing the purine diet.