Metabolism | Regulation of Gluconeogenesis

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  • Опубликовано: 12 июн 2017
  • Official Ninja Nerd Website: ninjanerd.org
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be continuing our discussion on gluconeogenesis, where we go into more detail on the regulation of gluconeogenesis as well as the enzymes involved in this process. We hope you enjoy this lecture and be sure to support us below!
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    #ninjanerd #GluconeogenesisRegulation #Metabolism

Комментарии • 264

  • @renivp3208
    @renivp3208 Год назад +59

    This man is single-handedly saving the grades of students taking biochem

  • @shayamorre2882
    @shayamorre2882 5 лет назад +280

    Who are you!? And why are you just so amazing? Please continue. I’m shouting you out at graduation!! Thank you for being a magical deliverer of the teachings of this once evil subject which is actually fun now.

  • @nero91
    @nero91 6 лет назад +91

    "one mor thing, to finish off" - Half the video left.
    JK'ing my friend, love your videos. Biochem exam in 2 days and you give me confidence.

  • @monarch3507
    @monarch3507 Год назад +55

    People don't realise how important public speaking skills are for a teacher... I have tried to watch the same topic elsewhere but fell asleep in the middle of the video... You just are amazing Prof...

  • @piyushsumera9076
    @piyushsumera9076 6 лет назад +192

    No matter ho much technology advances,The best way to study is by Classroom method and anyday the Erase board explanation will have edge over those fancy presentations..Because teacher can never get involved with the teaching by that premade presentations and You prove that again and again.
    You dont have an idea How many videos and sites I have browsed to go through this Tandem enzyme regulation..And You explained it ridiculously easily. Thanks a ton man !!!

    • @lailashoukat714
      @lailashoukat714 2 года назад +1

      the best way is teaching on board and then showing gross pics through slides.

    • @signalrod2213
      @signalrod2213 2 года назад +7

      but also only because of advanced technology this method works for many, the key difference is that you have the ability to pause or rewind, which you can't do irl in class

    • @praisehart7737
      @praisehart7737 Год назад

      @@signalrod2213 if more professors allowed students to take them back without making them feel bad that'll be the case in real life too

    • @signalrod2213
      @signalrod2213 Год назад

      @@praisehart7737 it's not exactly like that: putting myself in professors skin, how is it professors fault that I zoned out for 15 mins, and I don't feel like studying rn, I rather do it in 40 mins. You can't just listening to a lecture when you are tired of it and don't feel like you are accepting all the information, you can't just stop and look up some other topic, which you missed, and spend like 30 mins learning that first and then coming back to this one

    • @signalrod2213
      @signalrod2213 Год назад +1

      @@praisehart7737 it's subjective, but personally for me studying in class is 15 times less productive than on my own in front of a screen

  • @frajwggg1568
    @frajwggg1568 6 лет назад +84

    Man those videos should have a millions views

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  6 лет назад +18

      +Frajw Ggg Hopefully someday soon! Thank you so much!

    • @Outono937
      @Outono937 6 лет назад +5

      I strongly agree with you!!

  • @SilentEagle2029
    @SilentEagle2029 4 года назад +121

    Biochem exam is in 36 hours, you have saved my life! Thank you!

    • @mehmetalitaspinar9938
      @mehmetalitaspinar9938 4 года назад +2

      Mines too

    • @studybiology9673
      @studybiology9673 2 года назад

      How was it?

    • @SilentEagle2029
      @SilentEagle2029 2 года назад +14

      @@studybiology9673 This was 2 years ago, I am graduated now and passed Biochem with an A, but from what I remember, that exam went terribly lmao. But it would've been even worse without this video, so my original point still stands, this man is a life saver!

    • @studybiology9673
      @studybiology9673 2 года назад +1

      @@SilentEagle2029 👍👍👍

    • @zzoldd
      @zzoldd Год назад +1

      @@SilentEagle2029 ooo congrats

  • @miriamwilliams9603
    @miriamwilliams9603 4 года назад +49

    Dude, what's your day job? are you a doctor? professor? The One? Thank you for everything!!!

  • @JohnSnow-vg4tz
    @JohnSnow-vg4tz Год назад +2

    This was so intense, but it was worth watching. I watched it twice and understood the concept. Thank you, Zack!!!

  • @eggs8352
    @eggs8352 5 лет назад +20

    If I discovered your channel during my biochem class maybe I understood the subject better. I'm just here because I felt the need to review these pathways because this is heavily related to the subjects I have trouble understanding with :(
    Thank you sir for making such efforts to help students understand these complex subjects. Keep the passion burning. Salute to your team!

  • @sarapamintuan1879
    @sarapamintuan1879 2 года назад +13

    i have been seeing many of your videos and i just want to say thank you! you´re so so so good at explaining!!!

  • @okodioscar7518
    @okodioscar7518 2 года назад +2

    This man is very good in teaching because he made work simple by adding jokes that makes fun in lectures. Is so amazing and I look for his channel first before others

  • @NastroArzurro
    @NastroArzurro 5 лет назад +6

    You simply make the best biochemistry-videos!!! Thanks so much man!

  • @sandraschmelzer9961
    @sandraschmelzer9961 Год назад +1

    I am eternally grateful for your videos. I've watched a few of them several times and I have your diagrams in my head which help me remember what is going on during all these metabolism pathways and cycles :-)

  • @nourhaedar1618
    @nourhaedar1618 3 года назад +2

    You've saved my education! Thank you from the bottom of my heart.
    -from a pharmacy student in Syria.

  • @Uds_Baduge
    @Uds_Baduge 5 лет назад +38

    You have no idea how much I love biochemistry now thanks to you!!! I used to HATE it with a passion before I found your videos!!!!! Thank you so much!!!!!!!!!!

    • @karinsedlakova6316
      @karinsedlakova6316 5 лет назад

      same here :D

    • @Antoniooo1206
      @Antoniooo1206 4 года назад

      @@karinsedlakova6316 Same here. Started to love it because of him. It's fascinating how our body deals with everything, really asthonishing.

    • @solomonyokim6762
      @solomonyokim6762 2 года назад

      Same too.

  • @hanamostafa5268
    @hanamostafa5268 2 года назад +3

    Thanks so much!! You man is a true legend, and your videos is so valuable, you make a very complicated and long topic that I hated in Uni into a story with smiley enzymes and simple metabolism :) Thanks for being there and always trying to make your best and for the tonnes of efforts that is placed in these videos, Looking forward for more videos Ninja Nerd!!

  • @osielcecenas7669
    @osielcecenas7669 4 года назад +11

    restudying gluconeogenesis for my MCAT & I can say this is probably the best source I have had for information. Better than khan academy and Kaplan MCAT test prep

  • @paulinaleon6029
    @paulinaleon6029 4 года назад +3

    What a beautiful way to explain biochemistry, I entIrely love your channel!

  • @Luna-xl7dv
    @Luna-xl7dv Год назад +1

    It was absolutely fun and enjoyable, thanks for being there, you're a miracle that happened in my life ❤❤

  • @32-gokilavanis95
    @32-gokilavanis95 4 года назад +5

    Really amazing lecture.... Now I am interested to study biochemistry.. Thanks a lot for giving me hope ❤❤❤

  • @rajhellskitchen3658
    @rajhellskitchen3658 2 года назад

    We are grateful for ppl like you. Thank you bro

  • @janbazkhan4222
    @janbazkhan4222 6 лет назад +1

    hii sir ur lectures are really fruitfull the way u explain the things is very esay to understand ..i mostly follow ur lectures for my MACs exam preparations.bravo and praiseworthy...

  • @user-hw9bh9ro3t
    @user-hw9bh9ro3t 5 лет назад +9

    teacher who I never have like him , thanks from all my heart

  • @alih6953
    @alih6953 3 года назад +1

    Your videos are amazing. They deserve a million. Some silly youtubers buy a t-shirt and get 1 million that I don't agree with You deserve everything

  • @mehrzikamel7123
    @mehrzikamel7123 3 года назад +2

    You are amazing man my appreciation to you, biochimistry is so cool with your explanation and encourage student to love the whole medicine big thks dude)

  • @dr.varsharajan3153
    @dr.varsharajan3153 2 года назад

    Seriously dude ...such a wonderful explanation .. thankyou for making me understand this concept

  • @laluna5548
    @laluna5548 5 лет назад +1

    If you ever go out of your mind and decide to visit a shitty town of Belgrade, Serbia-you have a place to stay free of charge. I am not even kidding. You are my hero! Thank you so much. I am bad at memorizing, but understand logic-and that is what you use. Simply amazing :)

  • @jacquelinelabovitz4613
    @jacquelinelabovitz4613 6 лет назад +1

    best teacher out there!

  • @saraa.h3787
    @saraa.h3787 4 года назад +1

    this channel deserves 1 million subscribers and moooreee

  • @gattac900
    @gattac900 5 лет назад +2

    Best bio-chem vids in the RUclips.

  • @umerbinshabir6561
    @umerbinshabir6561 5 лет назад +2

    How beautiful it was.....thank you sir❤️

  • @888167
    @888167 5 лет назад +37

    At 7.48 you probably meant "in the muscle" not "in the liver". Otherwise it would be Glucokinase not Hexokinase
    Great video as always mate you guys are a blessing

    • @erwinbla1401
      @erwinbla1401 4 года назад +5

      Gucokinase is just one specific isoform of Hexokinases -> Glucokinase = Hexokinase4

    • @seren1104
      @seren1104 3 года назад +1

      yeah, it should be glucokinase cause we're in muscle

  • @rizwanilyas4289
    @rizwanilyas4289 2 года назад

    No one can compete such a great legend 🙂

  • @dondamishitha468
    @dondamishitha468 4 года назад

    Your like osm sir
    Really your videos boosting me confidence in biochemistry
    Our teachers just read ppt, rather they explain nothing, u r saving me in building up my subject in biochemistry
    Thank u very much😊

  • @whatev3857
    @whatev3857 3 года назад

    Zach, thank you so much, I finally understood it thanks to you💓💓💓

  • @mujtabaalizafar5680
    @mujtabaalizafar5680 4 года назад +1

    the last two minutes of this video >>>> literally everything

  • @AIZIKOVICHLARA
    @AIZIKOVICHLARA 4 года назад +3

    Great explanations! Thanks a lot ! (:

  • @marbeliscopello7153
    @marbeliscopello7153 Год назад

    Muchas gracias, muy bonito la interrelación entre el músculo, hígado y sangre en la gluconeogenesis.

  • @potatowithlimbs1335
    @potatowithlimbs1335 3 года назад

    u the best dude .... seriously u saved my life !!

  • @ughsirius
    @ughsirius 3 года назад

    THANK YOU SOOOO MUCH!! YOU'RE A LIFE SAVER ❤

  • @montaserhattab6152
    @montaserhattab6152 5 лет назад +58

    19:50 absolutely nooothing lamo

  • @Sadaf0711
    @Sadaf0711 2 года назад

    Thanks a lot for clearing the whole concept

  • @SalmaAhmed-kt2nu
    @SalmaAhmed-kt2nu 5 лет назад

    thank you for everything that you do

  • @motivationpilldaily
    @motivationpilldaily 2 года назад

    Thank you so much! This was amazing.

  • @manulanimsara
    @manulanimsara 3 года назад

    You are the best thing that i found on youtube brother❤️😍

  • @MuhammadTanveer-vt4xu
    @MuhammadTanveer-vt4xu Месяц назад

    Amazing explanation.Thanks Sir

  • @saimsiddiqui9893
    @saimsiddiqui9893 Год назад

    Man you make it so easy, thanks alot

  • @pierpaolotofani3929
    @pierpaolotofani3929 5 лет назад +2

    Great video. You are very talented !

  • @sandemichael7242
    @sandemichael7242 Год назад +1

    I love your lecturers sir just keep it up 🙏🙏

  • @technooooooooooful
    @technooooooooooful 6 лет назад

    you are simply great, students from Serbia support you!!

  • @sachinilakshika2213
    @sachinilakshika2213 5 лет назад +1

    perfect explanation!

  • @alirezaahmadi1777
    @alirezaahmadi1777 2 года назад

    Perfect teaching process ❤❤😍

  • @macebunny5516
    @macebunny5516 5 лет назад +1

    Amazing ... thank you!!!

  • @zaharramaearucan6479
    @zaharramaearucan6479 2 года назад

    Thank you so much! Im a huge fan here from the Philippines. I am currently taking my 3rd year in college.

  • @Aresearcher
    @Aresearcher 3 года назад

    Thank you for amazing lectures

  • @minatonamikaze3193
    @minatonamikaze3193 4 года назад +1

    Great video, Thank you

  • @IRENESAKAYA
    @IRENESAKAYA Год назад

    It's awesome , u deserve the very best Mr😇💯

  • @drlight7547
    @drlight7547 3 года назад

    very helpful 😍 THANK YOU!

  • @MegaCheerleader1999
    @MegaCheerleader1999 Год назад

    Thank you so much!!! So useful!

  • @factsinshortslm
    @factsinshortslm Год назад

    From now on, I should pay the tuition for you. Btw, you're videos are not boring at all, I enjoy watching them . Biochemistry is fun with YOU and ONLY YOU.

  • @sarrahkhanrahim2917
    @sarrahkhanrahim2917 7 месяцев назад

    You are seriously a life saver!Ive read few comments and totally can relate with them you truly are very good at your work.I see you erasing your mistakes with your fingers pls use a finger cap or something as those ink molecules can be harmful or even carcinogenic.Your safety is very important to your students and your family!
    one of your students from India❤️

  • @AishaGama-sl7ll
    @AishaGama-sl7ll 7 месяцев назад

    This is an amazing explanation

  • @mazinesam7183
    @mazinesam7183 6 лет назад +11

    thank you for making this difficult topics easier to us
    You are even better than khan academy 💀for real.thank you❤

    • @IWAC2013
      @IWAC2013 4 года назад

      way better, its not even close tbh

  • @ughsirius
    @ughsirius 3 года назад +3

    I have a question: why does a higher ADP/ATP ratio (as in a low energy state within the cell) inhibit Pyruvate Carboxylase and Fructose 1,6 Bisphosphatase? Don't we need more energy in a low energy state? And so shouldn't gluconeogenesis increase when the cell has low energy, so more glucose is made and can be broken down for energy?

  • @J3ug
    @J3ug 2 года назад +1

    Also Glucagon phosphorylates Pyruvate Kinase and therefore inhibits conversion of PEP back into Pyruvate.
    This has the effect of diverting PEP to the synthesis of glucose!

  • @eduardob.r.2087
    @eduardob.r.2087 6 лет назад

    Muito obrigado!!!!! You're amazing, dude!!

  • @lina_dader
    @lina_dader 5 месяцев назад

    amazing man! god bless you! thank you so much !

  • @zns2871
    @zns2871 5 месяцев назад

    Thank you for this great inspiration

  • @virtuesbernadettecadile6869
    @virtuesbernadettecadile6869 3 года назад +1

    Thank you so much!!

  • @shambhavigupta4263
    @shambhavigupta4263 4 года назад +2

    shoutout to this man for making me pass biochem

  • @user-qq7ww4ub6k
    @user-qq7ww4ub6k 4 месяца назад

    Thankuu so much...your teaching method outstanding

  • @sabelomanqobatembe9760
    @sabelomanqobatembe9760 5 лет назад

    videos are cool make it easy for many people to understand and i would to see more videos such as malonyl coA pathway ,fatty acid biosynthesis and many more other than that you the best.

  • @shreeshchakraborty3121
    @shreeshchakraborty3121 4 года назад +1

    Sir, You are amazing ❤️

  • @AshwaniKumar-gk9ng
    @AshwaniKumar-gk9ng 4 года назад +2

    Love from India
    Thank you so much sir

  • @iloveu136
    @iloveu136 2 года назад

    thank you for everything💞

  • @andreiasousa9688
    @andreiasousa9688 6 лет назад +30

    Thanks again for all the videos! Just a random question/suggestion: would it be possible for you to put a final picture of the board in the end? Sometimes it would be really helpful to check a little detail instead of watching the whole video again! But anyways, I'd really like to thank you for all the content. Y'all are just amazing

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  6 лет назад +36

      This is something we have recently started to do in all of our videos. Thanks for the suggestion!

    • @andreiasousa9688
      @andreiasousa9688 6 лет назад +3

      Ninja Nerd Science wow thanks! That's just great. Can you please check my previous comment on the gluconeogenesis video? :)

    • @farisabbas7897
      @farisabbas7897 6 лет назад +1

      Andreia Filipa Lopes Sousa +1

  • @lalith23
    @lalith23 3 года назад +1

    Thank you so much ❤❤

  • @minaltariq1191
    @minaltariq1191 4 года назад +6

    Thank u so much .... 👌✨
    It's awesome ....
    MashAllah ....
    May ALLAH ♥️ bless u with endless blessings ✨😊

  • @anuachu2146
    @anuachu2146 5 лет назад +1

    Awsome sir,we love you more.....

  • @popitandrelax
    @popitandrelax 4 года назад

    explained
    AMAZİNG!!!
    !!رائع الشرح
    Açıklama şahane!!!

  • @romagebreyesus1590
    @romagebreyesus1590 4 года назад

    l enjoyed all your explanations.

  • @muhammadhuzefa3568
    @muhammadhuzefa3568 3 года назад +1

    You are KING ❤️

  • @BRAVE_AGAINST_MYSELF
    @BRAVE_AGAINST_MYSELF 4 года назад +1

    Thank you so much

  • @janhvi521
    @janhvi521 2 года назад

    Nice work!!

  • @andahuzaifa5081
    @andahuzaifa5081 5 лет назад

    Brother.... very helpful video...👍👍👏👏

  • @sahibwahab4867
    @sahibwahab4867 Год назад

    Thanks sir today I clear my biochemistry only because of you

  • @udarachandrathilaka5200
    @udarachandrathilaka5200 2 года назад

    Thank you very much.😍🤗

  • @abbasnasir8832
    @abbasnasir8832 3 года назад +3

    Biochem exam is in 15 hrs and he's gonna save me❣️

  • @user-sq3ls6sj7i
    @user-sq3ls6sj7i Год назад

    dude. THANK YOU

  • @hungrysamurai9785
    @hungrysamurai9785 3 года назад

    you are a hero

  • @sonykaviarasan4152
    @sonykaviarasan4152 7 месяцев назад +1

    Super u are clearly understand

  • @drghada-pe4um
    @drghada-pe4um 6 лет назад +1

    So helpful
    Thank you ❤️

  • @Kesenschaf
    @Kesenschaf Год назад

    Thank you !!!

  • @desmondlarteylaryea4637
    @desmondlarteylaryea4637 3 года назад

    It was really helpful
    Thanks 🥺🥺🥺

  • @alialiraqi2762
    @alialiraqi2762 2 года назад

    Amazing
    Thanks

  • @fazliddinabdiraimov6261
    @fazliddinabdiraimov6261 3 года назад

    Thank you very much

  • @user-lj1zx5kt7k
    @user-lj1zx5kt7k 4 года назад

    I AM very thankful to you

  • @sruthisaravanan1342
    @sruthisaravanan1342 3 года назад

    Thank you ☺️

  • @kinzaasif7241
    @kinzaasif7241 3 года назад

    justt cannot thankyouu enough !!!