Regulation of Glomerular filtration rate | Tubuloglomerular feedback | Renal system physiology

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  • Опубликовано: 7 фев 2025
  • Physiology lecture on renal physiology details regulation of glomerular filtration rate (GFR) including myogenic mechanism and tubuloglomerular feedback
    Learn how myogenic mechanism causes changes in the diameter of afferent arteriole and renin angiotensin system in tubuloglomerular feedback causes changes in afferent as well as efferent arteriole
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Комментарии • 37

  • @khushbuchoudhary8496
    @khushbuchoudhary8496 3 года назад +3

    Mam found ur explanation to be very concept clearing....thank you mam .....i cant figure out why it not shared much

    • @PhysiologyOpen
      @PhysiologyOpen  3 года назад +2

      Thanks Khushbu. Glad you liked it. It’s ok. I just make the videos for as much help as I can. Hope you share it to more students so they may benefit. Thanks again

  • @mysterious3348
    @mysterious3348 3 года назад +5

    Mam , u really give us a crystal clear information about the topics ,, I really regret that ,, u should have started this channel when I was first year ,,, 😎😎,, thank u mam

  • @youtubeqwe495
    @youtubeqwe495 3 года назад +2

    Ma'am your videos are helpful for 1st year BVSc students also...... Thank you for these Awesome videos .. It cleared many doubts which I encountered while reading other texts

  • @bublisoniyak6227
    @bublisoniyak6227 3 года назад +2

    Thank you so much ma'am!! 🙏🙏🙏
    Flowcharts are extremely helpful ma'am 🙌🙌🙌

    • @PhysiologyOpen
      @PhysiologyOpen  3 года назад

      Exclusively by me for all the inquisitive learner’s...😊

  • @dharshandharshan4541
    @dharshandharshan4541 Год назад +1

    Really Clear vedio with nice flowcharts mam.....good teaching

  • @pdcbamabama1890
    @pdcbamabama1890 2 года назад +1

    mam awesome explanation ..Helped me a ton.

  • @ashwinabraham9799
    @ashwinabraham9799 2 года назад +1

    Awesome video

  • @vinaygundalli2104
    @vinaygundalli2104 Год назад +1

    Tq mam ❤️

  • @zqr444
    @zqr444 11 месяцев назад +1

    Mam can u tell which book u refer for physio and which is best book for physio that helped u pls.,

    • @PhysiologyOpen
      @PhysiologyOpen  11 месяцев назад

      Guyton , ganong …if not able to read them then understanding medical physiology by Bijlani

  • @brahmamg1885
    @brahmamg1885 3 года назад +1

    Mam will there not be increase in resistance of systemic vessels if mean arterial blood pressure increases thus causing renal plasma flow to decrease

    • @PhysiologyOpen
      @PhysiologyOpen  3 года назад

      It depends on how BP is being caused. In case of renal artery stenosis that may be the case but otherwise whenever BP increases , it will cause increase in RPF , since BP is the driving for e for flow. Also see this increase in RPF and then of GFR causes decreased activation of angiotensin via tubuloglomerular feedback. This in turn will decrease BP

    • @brahmamg1885
      @brahmamg1885 3 года назад +1

      @@PhysiologyOpen Thank you mam

    • @PhysiologyOpen
      @PhysiologyOpen  3 года назад

      Most welcome

  • @brahmamg1885
    @brahmamg1885 3 года назад

    Mam acc to graph between arteriolar resistance and RBF it means that if resistance decreases RBF should increase .But if Mean arteriolar BP decrease due to arteriolar dilatation(decrease in resistance) then RBF should decrease ?

    • @PhysiologyOpen
      @PhysiologyOpen  3 года назад

      Graph represents experimental conditions in what effects what...cause and effect in single direction...these graphs represent if there is change in arteriolar resistance (x axis) what will be the effect on RBF and GFR ...that’s all

    • @brahmamg1885
      @brahmamg1885 3 года назад

      @@PhysiologyOpen Thank you mam

    • @PhysiologyOpen
      @PhysiologyOpen  3 года назад

      Welcome

  • @aftabrayyan6524
    @aftabrayyan6524 Год назад

    Mam is it fron Guyton mam?

  • @newlynursingwithsneha_2002
    @newlynursingwithsneha_2002 3 года назад +2

    🥳🥳🤩🥰😘😘😘😘😘😘😘😘😘😘😘😘😘🌷🌷🌷🤩🤩🤩thank you mam for removing my frustration

  • @That-physiology-guy
    @That-physiology-guy 26 дней назад

    Ohk let me explain..
    When the map goes high.. From normal upto 200 mmhg.. The renal arterial pressure goes high.. Thus rbf increase.. And thus gfr increase b.. Thus increase in filtration and thus increasing in nacl I'm the short segment of thick asending limb of loop of henle lined by macula densa.. Then the na cl move into the macula densa cell(mcd)via nkcc2.. And increase in na and cl cause Osmosis and increase in water indise the cell.. Thus activate the volume sensitive anion channel Or maxi anion channel.. Thus cl efllux via those anionn channel and the cell got depolarize and that depolarization activate Penexxin channel.. Thus ato moves out at the basolateral side via penexxin and also maxi anion channel.. Then at the ECM present of ecto atpase that convert atp to adp to adenosine finally.. Then those adenosine act on a1r via gi pathway inhibit jg cell to release renin, adenosine act on affernet arteriole by a2b receptor via Gq pathway and also act a1 receptor to conduct gi pathway to reduce the camp and pka to prevent the pka mediated inactivation of MLCK.. Thus promote affernet arteriole vasoconstriction.. And that adp act on p2y receptor via Gq and adenosine act on a2b via Gq contraction of extra and intraglomerular cell to compress the vessel and reduce the lumen size thus reducing capillary surface area thus reducing the GFR.. That reduction of gfr when bp goes high prevent excess electrolyte and water exceetion and prevent electrolyte imbalance and also prevent Vessel injury in renal circulation 😎also high amount of cl inside the MCD ultimately move out so no cl inside..this no activation of NOS (3) thus no NO release by MCD cell and prevent affernet arteriole vasodilation via NO❤

    • @PhysiologyOpen
      @PhysiologyOpen  26 дней назад

      Great...do you want the job of writing my script

    • @That-physiology-guy
      @That-physiology-guy 26 дней назад

      @PhysiologyOpen I would love to.. How can i contact you.. I have lot of things to share with you about physiology.. Excited!
      Nd need a job 🥲

    • @That-physiology-guy
      @That-physiology-guy 26 дней назад

      @PhysiologyOpen I would love to❤.. How can I contact you..I have lot things to share with you about physiology..nd need a job also