Pyruvate dehydrogenase complex

This is a short animated video on the function of Pyruvate dehydrogenase complex. Pyruvate dehydrogenase complex (PDC) is a complex having three enzymes that converts pyruvate into acetyl-CoA by the mechanism of decarboxylation reaction of pyruvate.

[@sevenselevens4951]

literally the cleanest explanation i've seen, great job

[@mohammedabid6438]

You explained 5 pages of my biochemistry textbook in 2 minutes

[@imamabraham]

yeah man

[@imamabraham]

i just waisted 29 minutes on a video for decarboxylation of pyruvate and didnt get anything, the greatest explanation in less then 3 minutes... the best.

[@DresdenDoll79]

Great animation. By far the best video I've found that explains this process. Thank you!

[@mojomonger]

finally! something that gets the main ideas down in a clear quick way.

[@santelmo5222]

This was a great visual, thank you!

[@bruhzone]

45 mins of class into 3 minutes may allah bless you and give you all your hearts desires. may you and your loved ones thrive in the earth and in the hereafter. amen

[@sheelamsrujan9683]

Really it made the concept very very very understanding and easy ....thank you ...❤️

[@mythstapes9830]

i've literally reseached on the topic for 2 hours straigh and didn't understand a thing; thanks to you i understood that it's a very stupid and basic reaction. thank you SO much

[@thaibinhnguyen6333]

A very depictable animation. Thank you^^

[@imenehk2048]

Wow 2minutes and it’s all clearly explained! Tnxx

[@khatirbehlol1449]

Ths wz tremendous job... For quick overview... N crucial days of preps... Thank uuu

[@bluejay2867]

This visual aid helped tremendously. Thank you so much!!

[@richanarayan5166]

This was So quick n easy to learn 👍👍

[@mustafaurfi6283]

Bro I absolutely love your videos. Thank you!!

[@yourmamazz]

great animation to get the basic understanding

[@theprantikdeka]

ome of the best explanation

[@yukine_it9483]

Thank you for this amazing video! :D

[@fellforfall9802]

very clear, thanks a lot!!

[@ZeeshanAhmad-yg8pk]

Wonderful work.

[@shahlaiqbal3635]

Fantastic explanation 🤗

[@medecin6248]

رائع 🌹 بارك الله فيك

[@keerthanakumar8832]

amazing explanation thank you

[@sumanpal8656]

Thank you for such a clear explanation

[@PLANTABYGIA]

Great short explanation

[@famyrahl1278]

this was so helpful!

[@prarthana2692]

What a smart explanation...

[@shinn-tyanwu4155]

Excellent presentation 😊

[@fatimahmakun3455]

Simple and Nice
Thanks a lot

[@selcukpolat2371]

Great video,thanks

[@susanzhou3866]

wow clear and quick!

[@shekinah6853]

great stuff!!!!

[@bublisoniyak6227]

Wonderful!!! ❤

[@nlnrao123]

Simple and superb

[@joshchronis3750]

Awesome video

[@jessicalv6442]

Jesus, this is amazing!!!!!!! Save my life!!!

[@NehaKhan-zf1nk]

Thank you 🤗🤗

[@Jatinmamgai]

Thank you so much

[@garimarathor2091]

How do you make acetic acid in the E2 complex?

[@lolitsme6]

thank you so much 💙

[@hakob2168]

best explanation

[@abdulazizalghanim6437]

thank u sir, you saved me

[@himanshitanwar7907]

very helpfull video

[@drsirisha2918]

Well explained

[@piyushakadekar5370]

Nice explained

[@ethanbaird5058]

this is great

[@georgette9203]

thank you

[@XxGameMaster999xX]

the music is so distracting

[@RudebwoyPmask]

Facts

[@ammarali1914]

Great job! Kuddos to creators

[@kindaalzouabi6845]

thank you❤❤❤❤❤❤❤❤

[@lauramarchisella9502]

great

[@jongelb9603]

At 1:48 I’m pretty sure that the oxidized product of E2 catalyzed process is not acetic acid but a thioester

[@sevenselevens4951]

yeah i think you are right

[@Winter_____]

👏👏👏

[@miloshalda2031]

cool

[@nandinithakur20]

Was this topic that easy? Man i read it for an hour and I didn't get a thing and u just took 2 mins.... Now even if i try I won't forget this😂

[@janvisharma2048]

😀😀❤️❤️

[@saaabji7083]

Can somebody explain why E1 is called dehydrogenase when it carries out the decarboxylation reaction?

[@parijat7526]

Because also catalyzes the oxidation/dehydrogenation of Hydroxymethyl group of Hydroxymethyl-TPP to Acetyl group

[@dontrock]

thaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaank uu

[@nishantthakur6896]

BRO please tell the mechanism too ..

[@arielleaiken]

i love the music

[@abdulbasitghauri8934]

Why pyruvate directly don't enter to Krebs cycle?

[@robinsondinh2412]

It has to be converted into acetyl coA so that it can combine with oxaloacetate and form citrate

[@-_-_-_-_-_-_-_-_-_-_-_-...]

vurrryyyyyy gud! (indian accent)

[@mbbslovers9572]

Nice explained but , I think E1 is pyruvate Decarboxylase not dehydrogenase .

[@sevenselevens4951]

no it's dehydrogenase

[@awanier786]

E1 is pyruvate decarboxylase + thymine pyrophosphate not pyruvate dehydrogenase

[@12deimos]

It is called p decarboxylase or p dehydrogenase, those are synonyms.

[@m0ony1]

Dr Majid Awan They’re synonyms so both are right pyruvate dehydrogenase (decarboxylase) complex

[@Sveccha93]

*thiamine

[@shahimtajulhaque9786]

All explanations are uulala, but don't mind why you try to change your accent 😟

[@user-kz4it1jx8c]

nice pronounciation

[@ashleymendoza4019]

good video but i hate the music

[@RedHeadSH0T]

Music is horrible

[@Botanophilist]

Thank you so much