When I was studying biology 40 years ago, I just knew there was more to the story! I couldn't believe convergent evolution evolution would happen randomly! There had to be a mechanism for environmental influence
Click that CC button to see what he is saying. Definite fuel for disaster movie. "Existential risk" may not be an exaggeration. There is evidence that people had much better memories in the past. Possibly diminished by some change to the epigenome? Though, I suspect, they did a lot more rhymes with toddlers, and young kids. Rote memory is practically a dirty word, today. But just because you do rote memory exercises does not mean you can't teach reasoning and creativity as well. I have drifted off-topic. I suspect lead and many other exposures have harmed us. Is it truly permanent? Can we do something to reset it? Is there even a default state? If reset, would we lose a lot of important adjustments that have been with us for eons? What about those Yamanaka factors? Or maybe there is another one or set that does do a reset. So many questions. I read about this nearly 20 years ago. Though I had no idea, it was effectively permanent. I figured it would fade fairly quickly. It makes one wonder about what the impacts on children are from a father who did all sorts of drugs, and then quit, settled down and had a family. That describes vast numbers of people who grew up in the 1980s and 1990s. I was the oddball, never smoked, drank, or used at all, but obviously I wasn't very popular either. I always wanted to live a long time. Most men smoked back in the late 1940s until the early 1980s. Mostly it shot up during WW2, when they put cigarettes in every soldier's gear. So many toxins. Our farmland is covered with lead from the top-selling pesticide in the early 1950s, lead arsenate and auto exhaust. And, even today, from crop dusting aircraft virtually all of which still used leaded aviation fuel, and from bone meal fertilizer. For countless generations, humanity was besieged by smallpox. For at least 3,500 years in the old world, 1/3 of all children died of smallpox, and everyone else was scared all over, and some left blind. Many did not even name their children until they had smallpox and survived. In the early 1800s, large numbers started to get inoculated, but there was still a significant risk of death. It was not until vaccination, that you had a very low chance of death. And now no one dies of smallpox because we eradicated it. Probably the single greatest accomplishment of humanity after agriculture. I have got to think that epigenic effects from smallpox must be present. Probably from plague, polio and leprosy as well. Almost certainly we can develop tools to edit epigenetics...if not a blanket reset...targeted repairs. Though, Congress is paranoid and outlaws so much stuff that can make large positive changes in our lives. I wonder if being routinely electrocuted affects the epigenome. I grew up in a house where it was always wet in the laundry, and to load or empty the washer or dryer meant being continuously electrocuted when you touch either appliance or anything wet in them. You get used to it. But, it is still unpleasant, and requires effort to move your arms where you intend. I am sure it would kill anyone with a weak heart. Must have been that way at least a decade.
Correct..that is because his life’s work and energy is directed in other disciplines, which includes finding out how many generations back the stick was methylated up your arse. If you have skills to improve someone else’s process, find a solution not derail the entire purpose of this talk, which was both coherent and a point far more memorable than the audio.
Thank you for the feedback! If you'd like to view the transcript, you can see it on my website here - everythingepigenetics.com/episode/dr-michael-skinner-epigenetic-transgenerational-inheritence/
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Yes ..audio was very poor , but the information worth the work .I'm subscribed
When I was studying biology 40 years ago, I just knew there was more to the story! I couldn't believe convergent evolution evolution would happen randomly! There had to be a mechanism for environmental influence
This seems great but the audio and volume is off. Seems like such legitimate and detailed info but I couldn’t hear everything! It got annoying
Thanks for the feedback! One man band over here and currently getting help with this :) You can check out the transcript if you're interested.
❤thank you so much. This Intel is fascinating!😃 I'm using earphones so my audio quality is good😊
You're welcome :)
Delicious...
Click that CC button to see what he is saying. Definite fuel for disaster movie. "Existential risk" may not be an exaggeration. There is evidence that people had much better memories in the past. Possibly diminished by some change to the epigenome? Though, I suspect, they did a lot more rhymes with toddlers, and young kids. Rote memory is practically a dirty word, today. But just because you do rote memory exercises does not mean you can't teach reasoning and creativity as well. I have drifted off-topic. I suspect lead and many other exposures have harmed us. Is it truly permanent? Can we do something to reset it? Is there even a default state? If reset, would we lose a lot of important adjustments that have been with us for eons? What about those Yamanaka factors? Or maybe there is another one or set that does do a reset. So many questions.
I read about this nearly 20 years ago. Though I had no idea, it was effectively permanent. I figured it would fade fairly quickly.
It makes one wonder about what the impacts on children are from a father who did all sorts of drugs, and then quit, settled down and had a family. That describes vast numbers of people who grew up in the 1980s and 1990s. I was the oddball, never smoked, drank, or used at all, but obviously I wasn't very popular either. I always wanted to live a long time. Most men smoked back in the late 1940s until the early 1980s. Mostly it shot up during WW2, when they put cigarettes in every soldier's gear.
So many toxins. Our farmland is covered with lead from the top-selling pesticide in the early 1950s, lead arsenate and auto exhaust. And, even today, from crop dusting aircraft virtually all of which still used leaded aviation fuel, and from bone meal fertilizer.
For countless generations, humanity was besieged by smallpox. For at least 3,500 years in the old world, 1/3 of all children died of smallpox, and everyone else was scared all over, and some left blind. Many did not even name their children until they had smallpox and survived. In the early 1800s, large numbers started to get inoculated, but there was still a significant risk of death. It was not until vaccination, that you had a very low chance of death. And now no one dies of smallpox because we eradicated it. Probably the single greatest accomplishment of humanity after agriculture. I have got to think that epigenic effects from smallpox must be present. Probably from plague, polio and leprosy as well.
Almost certainly we can develop tools to edit epigenetics...if not a blanket reset...targeted repairs. Though, Congress is paranoid and outlaws so much stuff that can make large positive changes in our lives.
I wonder if being routinely electrocuted affects the epigenome. I grew up in a house where it was always wet in the laundry, and to load or empty the washer or dryer meant being continuously electrocuted when you touch either appliance or anything wet in them. You get used to it. But, it is still unpleasant, and requires effort to move your arms where you intend. I am sure it would kill anyone with a weak heart. Must have been that way at least a decade.
Defenitely did not get his Phd in sound engeneering.... why upload such bad sound
Thanks for the feedback, Eric! I'm working on getting better at this.
Correct..that is because his life’s work and energy is directed in other disciplines, which includes finding out how many generations back the stick was methylated up your arse.
If you have skills to improve someone else’s process, find a solution not derail the entire purpose of this talk, which was both coherent and a point far more memorable than the audio.
@@angelinaderpina6210 Thank you!! ^^^
Audio is totally fucked...
Thank you for the feedback! If you'd like to view the transcript, you can see it on my website here - everythingepigenetics.com/episode/dr-michael-skinner-epigenetic-transgenerational-inheritence/