Wow !! I could listen to this for hours. Impressive how clear and logical the answers given by Dr. Svante Pääbo are. Especially impressed that such an eminent researcher and highly recognized scientist can be understood by common people like me who doesn't no knowing about all this. Thank you Dr Svante for your research, your precious time and the quality of your communications.
I am from Jerusalem, Israel. I was spellbound by you webinar, the clarity of the explanations, and the passion and fun that is clearly pushing you on. Also the questions relating to susceptibility to covid 19,and other ailments, and it's relation to old dna"that was worth while to keep ", and the liabilities it brought with it. Would love to hear more! Many thanks
I took part in the UK Biobank pain questionnaire. Happy to have played a very tiny part in Dr Paabo's research. Thank you for a fascinating lecture and making it available on this channel.
I keep rewatching Svante!!.. there’s a good number of lectures on YT.. but this one is RECENT 😱🥰🥰.. I just keep watching and watching!! SOOOOO interesting!!
Vaccum cleaning RUclips for these lectures and talks. Filling a playlist with them. Enjoying them so much. We need to encourage the youth to educate and go explore all these scientific fields, be it Geology, Anthropology, Archeology, Biology, Chemistry, Physics....... These fields of research will be the big thing in the 21. Century in trying to answer the many questions about the evolution of humans/animals/plants we have today. Scientists also need to have better funding. It's that important.
Very instructive presentation, thank you both very much. I also had a childhood fascination with archeology but life took me somewhere else (but still in biology). Fascinating in it,s deepest meaning; please keep us appraised.
It could be due to the different cranial morphology of the neanderthaal - it being more oval - that leads to birthing difficulties and so a premature birth when the skull is smaller would have been an evolutionary adaption to resolve this problem - but of course this would lead to another dilemma - having to cope with a premature baby. It could be that H. sapiens resolved these problems - by a mutation which altered the morphology of the skull - making it more 'vertical' in shape (by vaulting up of the braincase). This would be a successful gene variation as more babies would survive.
Fascinating. I have the urge to have my dna mapped and follow along marking each allele that has Neanderthal origins. I’ve wondered what this dna means to modern humans in terms of expression.
Thank you for this presentation. Have Dr Paabo's findings concerning COVID-19 and chromosome 3 been published in a scientific journal? If so, and if the journal is in English, could you please provide the citation?
Native Americans and Aboriginal people in Australia share genes that no one else has. How does that factor in here? Do Native Americans also have the desonivan DNA? I'm assuming some could have both ancient DNA? Also, how did the ancient viruses DNA become 8% of our own DNA? How does that work? I really like the presentation. Well explained in layman terms.
Please provide link that Native Americans & Australian Aborigines share genes that no one else has. If true, this would completely change the current consensus of human population spread.
Quite interested in relationship between Sapiens and Neanderthals, Dynosovians and other net yet recognized other humanoid species. Cheers, Jan. Lelijveld.
I’m thinking Head Size MUST have been a factor in regards to Homo-Sapiens giving Birth to Neanderthal &/or Denosovian births… where early birth could have been the body’s only chance at both Mother & child staying Alive.
I wonder if native Americans carry the risk on chromosome three I noticed that David Reich said that the yamnia split and went to Europe India and North America Perhaps you have the genome of that kid from over by lake baikal and could see if this gene occurred there Also David Reich could check to see if that gene made it here My granddaughter and her mother have Covid and our Indian health service clinic just told them to stay home and take tylonal I gave them my oxymeter And some of the nutrients of dr Paul Mario’s math plus protocol Do you have any idea if we could get the test for this gene I know because my family has myotonic dystrophy that our ihs clinic will send a blood sample for testing if an American physician recommends it and it is free or covered by Medicaid Thanks for a wonderful program and thank dr paabo for a great book and wish him another eight years riding the crest of the breaking wave of scientific discovery in the field he created
Excuse-me to interact with your comments and questioning. But I wanted to say that I do feel there is so much to be discovered from native american for the history of human kind and its various migrations. I have noticed for example that some of them do have European features.
David Reich has NEVER claimed that the Yamnaya went to North American. The Yamnaya only date from 3300 - 2600 BC while North America was settled atleast 15,000 years BEFORE the Yamnaya.
Neanderthals are often considered a different species than modern humans. I find this interesting. Interbreeding is key to the biological species concept, which defines a species as members of populations that can interbreed with each other to produce viable offspring. (To be considered “viable,” the offspring must themselves be able to reproduce.) The evidence is in Neanderthals breed with modern humans and the offspring were viable which we know becomes most humans have 2-4% Neanderthal DNA. Just as breeds of dogs, despite size and looks are the same species, biologically speaking by definition, Neanderthals are the same species as modern humans because we mated and produced viable offspring.
Kittens Henderson. Until recently it was believed Sub-Saharan didn’t have any Neanderthal DNA. Now we know that a previous attempt out of Africa (before the one 70K ago - believed to be ~100K) meet neanderthals and then returned to Africa. This EARLY Neanderthal mixture is very obscure and wasn’t detected until recently and is only about 0.3 - 0.5%. That being when the non sub-Saharans left Africa -70k ago they met Neanderthals again and have 1-4% of the genes from them
Oof. The scientific name for Neanderthal is Homo Neandertalis. Modern humans are Homo sapiens. There were many other Homo species that went extinct. This has been settled for quite a while. Homo species are more akin to wolves, coyotes, and dogs than dog breeds. Modern dogs are all canis lupus familiaris. Foxes are in the same family but not the same species and can rarely, if ever, breed with the above.
@@joltjolt5060 It's a common misconception that different species can't interbreed. You just pointed out that polar and grizzlies interbreed. Polar, grizzly, and black bears are all new world bears. Species is a human construct based on nature, and get redefined often. As the evidence stands currently if species are in the same family, evolved in the same geography (where they'd have contact) , and have the same number of chromosomes there's a high likelihood they can have fertile offspring. This explains why polar and grizzly bears or coyotes and wolves have hybridized so well. Meanwhile, all cats have 38 chromosomes but captive big cat hybrids are usually unhealthy and sterile. Tigers, lions, and panthers evolved on different continents and never hybridize in the wild.
I had heard there was a Neanderthal variant that affected the COVID protein shell weakening it enough to help prevent it from infecting cells with its RNA. Is this true?
Have no idea but I've had a few people comment on how well i handle the cold (I'm Canadian). I don't think it's anything remarkable though and find people's reactions kind of amusing.
In fact, we are them. Their genes remain in us. It is a fraction, yes, but we recognized them as human enough to have children with them. The children concidered human.
Everyone just wants to know how the neanertal and denisovan genes exist today effect us today also 2nd would be more about them which is the same thing really - them in relation to us now. a psychiatrist was telling us about this genome that they have got into now. so he found it interesting. it is interesting. they foun d things out with this stuff. and found out about groups that were there that are blended in now with others. We have the rare georgraphic tongue. And we have relation to mongolia some 1/4 so that's more influenced by neanderthal. red hair the one grandmother had red hair when she was young we were told. so that's neandertal trait but then they said that the red hair now isn't neandertal. This one man's wife wanted to marry him because he was big and looked different. So one of their kids had red hair and her 2 girls had double crowns- cromagnon. He's big, too which they say happens when they interbreed too much. Their kids all looked different some more indian than others. The red hair and light skin's different. The boy had dark hair. The man was white and a big forehead or whatever and that's what happens or something with too much inbreeding. Then some of the men couldn't have kids in neandertals.
About that gene from the Neanderthals in the 3rd chromosome and the sensitivity to covid. If you take the point of view of China, it is very convenient that the people of european descent and the Indians are more sensitive to the covid because many of them carry the gene and that the Chineses (and the Japaneses and the Coreans) are much less sensitive to Covid because they don't carry that gene. Just thinking...
No one talks about how much Neanderthal DNA the Modern Humans already had when they left Africa. You had Neanderthals living in Israel. Israel is not far from Africa
Poor quality video, couldn’t read the charts , and the audio would have been better if the speaker would talk directly into mic, but an interesting subject..
I still don’t think it’s logical ..not to think humans developed alone on other land masses ...rather than Africa ....surely Asia ....Australia ...pacific islands ...surely the roots cannot just be from the African continent ......I think it’s to easy to think humans did not originate from different places ...understandably evidence is necessary ..... up why not alternative thesis in relation to the traveling of early mankind .....
@@Lioness1499 ....well science is showing otherwise ... .not that it really makes much diference ...but scuence is fact based conversation not argument ..
@@rosrebel Science is mankind BS. It has nothing do with Truth. Scientists are mere men trying to figure out creation. So saved the propaganda. It is based on a opinion.
I keep rewatching Svante!!.. there’s a good number of lectures on YT.. but this one is RECENT 😱🥰🥰.. I just keep watching and watching!! SOOOOO interesting!!
Wow !! I could listen to this for hours. Impressive how clear and logical the answers given by Dr. Svante Pääbo are. Especially impressed that such an eminent researcher and highly recognized scientist can be understood by common people like me who doesn't no knowing about all this. Thank you Dr Svante for your research, your precious time and the quality of your communications.
congratulation Dr. Svante Pääbo !!!
I am from Jerusalem, Israel. I was spellbound by you webinar, the clarity of the explanations, and the passion and fun that is clearly pushing you on. Also the questions relating to susceptibility to covid 19,and other ailments, and it's relation to old dna"that was worth while to keep ", and the liabilities it brought with it. Would love to hear more!
Many thanks
I took part in the UK Biobank pain questionnaire. Happy to have played a very tiny part in Dr Paabo's research. Thank you for a fascinating lecture and making it available on this channel.
Svante Paabo is one of this generations great creative geniuses
I am in Mexico. Congratulations and thankyou for your concern in these fundamental, applied science
Watching from NSW Central Coast, Australia. Many thanks for intriguing presentation.
This was marvelous! More! More! More!
I keep rewatching Svante!!.. there’s a good number of lectures on YT.. but this one is RECENT 😱🥰🥰.. I just keep watching and watching!! SOOOOO interesting!!
Vaccum cleaning RUclips for these lectures and talks. Filling a playlist with them. Enjoying them so much.
We need to encourage the youth to educate and go explore all these scientific fields, be it Geology, Anthropology, Archeology, Biology, Chemistry, Physics....... These fields of research will be the big thing in the 21. Century in trying to answer the many questions about the evolution of humans/animals/plants we have today.
Scientists also need to have better funding. It's that important.
I have been "vacuuming the internet" too. It is amazing the quality information available just by typing in topics: geology, evolution, DNA, ect...
Fantastisch! Dankeschön Professor Sven Paabo 💕🥰!
Very instructive presentation, thank you both very much. I also had a childhood fascination with archeology but life took me somewhere else (but still in biology). Fascinating in it,s deepest meaning; please keep us appraised.
Listening in Sutter Creek, California.
Canada here. I'm interested in how the genes affect us. And can't pass up listening to Dr. Svante Pääbo
Is it possible to reconstitute Neanderthals by back crossing in a multi-generational volunteer study group over 500 plus years. I am a 4%-er myself.
It could be due to the different cranial morphology of the neanderthaal - it being more oval - that leads to birthing difficulties and so a premature birth when the skull is smaller would have been an evolutionary adaption to resolve this problem - but of course this would lead to another dilemma - having to cope with a premature baby. It could be that H. sapiens resolved these problems - by a mutation which altered the morphology of the skull - making it more 'vertical' in shape (by vaulting up of the braincase). This would be a successful gene variation as more babies would survive.
Wonderful talk!! Thanks to everyone involved!!
Fascinating. I have the urge to have my dna mapped and follow along marking each allele that has Neanderthal origins. I’ve wondered what this dna means to modern humans in terms of expression.
Thank you for this presentation. Have Dr Paabo's findings concerning COVID-19 and chromosome 3 been published in a scientific journal? If so, and if the journal is in English, could you please provide the citation?
sub'd almost instantly after starting to watch; extremely interesting presentation; happy to find this channel, thank you for sharing.
Me too!
San Francisco Bay Area, CA-Worked for Dr. Cavalli-Sforza many decades ago @ Stanford University
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Because I love it, to learn something more about the ancient. Daniel Gent BE
Native Americans and Aboriginal people in Australia share genes that no one else has. How does that factor in here? Do Native Americans also have the desonivan DNA? I'm assuming some could have both ancient DNA?
Also, how did the ancient viruses DNA become 8% of our own DNA? How does that work?
I really like the presentation. Well explained in layman terms.
Please provide link that Native Americans & Australian Aborigines share genes that no one else has. If true, this would completely change the current consensus of human population spread.
Starts at the 6:00 mark.
Adding to my comment above - research work has pinpointed genes on chromosome 18q as being the ones that affect skull morphology.
Starts around 6:00.
Yamnaya?
I was born a few kilometers away from Neanderthal!
Quite interested in relationship between Sapiens and Neanderthals, Dynosovians and other net yet recognized other humanoid species.
Cheers, Jan. Lelijveld.
Thks to U both!!!!! Soooo informative.
Garland, a suburb of Dallas, Texas. (I am interested in how Neanderthals influenced the Indo-European population).
made em warlike
So informative, thank you
I am Puerto Rican with 1% Denisovan,2%Neanderthal,41% Italian,22% Spanish Celtic,17% Midleast, 7% African.
Héctor López
I’m thinking Head Size MUST have been a factor in regards to Homo-Sapiens giving Birth to Neanderthal &/or Denosovian births… where early birth could have been the body’s only chance at both Mother & child staying Alive.
Northern Ontario Canada (Jan 2, 2021)
Southern Ontario Canada (Jan 2, 2021) :)
I wonder if native Americans carry the risk on chromosome three
I noticed that David Reich said that the yamnia split and went to Europe India and North America
Perhaps you have the genome of that kid from over by lake baikal and could see if this gene occurred there
Also David Reich could check to see if that gene made it here
My granddaughter and her mother have Covid and our Indian health service clinic just told them to stay home and take tylonal
I gave them my oxymeter
And some of the nutrients of dr Paul Mario’s math plus protocol
Do you have any idea if we could get the test for this gene
I know because my family has myotonic dystrophy that our ihs clinic will send a blood sample for testing if an American physician recommends it and it is free or covered by Medicaid
Thanks for a wonderful program and thank dr paabo for a great book and wish him another eight years riding the crest of the breaking wave of scientific discovery in the field he created
Excuse-me to interact with your comments and questioning. But I wanted to say that I do feel there is so much to be discovered from native american for the history of human kind and its various migrations. I have noticed for example that some of them do have European features.
David Reich has NEVER claimed that the Yamnaya went to North American. The Yamnaya only date from 3300 - 2600 BC while North America was settled atleast 15,000 years BEFORE the Yamnaya.
Great stuff - thankyou. Wow.
I'm from London UK
Neanderthals are often considered a different species than modern humans. I find this interesting. Interbreeding is key to the biological species concept, which defines a species as members of populations that can interbreed with each other to produce viable offspring. (To be considered “viable,” the offspring must themselves be able to reproduce.) The evidence is in Neanderthals breed with modern humans and the offspring were viable which we know becomes most humans have 2-4% Neanderthal DNA. Just as breeds of dogs, despite size and looks are the same species, biologically speaking by definition, Neanderthals are the same species as modern humans because we mated and produced viable offspring.
Isn't that percentage related to Cacusiod people only. Negriod people do not have Neanderthal DNA.
Kittens Henderson. Until recently it was believed Sub-Saharan didn’t have any Neanderthal DNA. Now we know that a previous attempt out of Africa (before the one 70K ago - believed to be ~100K) meet neanderthals and then returned to Africa. This EARLY Neanderthal mixture is very obscure and wasn’t detected until recently and is only about 0.3 - 0.5%. That being when the non sub-Saharans left Africa -70k ago they met Neanderthals again and have 1-4% of the genes from them
By your logic grizzlies and polar bears are the same species, but they supposedly aren't.
Oof. The scientific name for Neanderthal is Homo Neandertalis. Modern humans are Homo sapiens. There were many other Homo species that went extinct. This has been settled for quite a while.
Homo species are more akin to wolves, coyotes, and dogs than dog breeds. Modern dogs are all canis lupus familiaris. Foxes are in the same family but not the same species and can rarely, if ever, breed with the above.
@@joltjolt5060 It's a common misconception that different species can't interbreed. You just pointed out that polar and grizzlies interbreed. Polar, grizzly, and black bears are all new world bears. Species is a human construct based on nature, and get redefined often.
As the evidence stands currently if species are in the same family, evolved in the same geography (where they'd have contact) , and have the same number of chromosomes there's a high likelihood they can have fertile offspring. This explains why polar and grizzly bears or coyotes and wolves have hybridized so well.
Meanwhile, all cats have 38 chromosomes but captive big cat hybrids are usually unhealthy and sterile. Tigers, lions, and panthers evolved on different continents and never hybridize in the wild.
Very good!
I am a hungarian from Canada
360p resolution does not allow reading the charts. Why not 480 or 720p?
Turn your phone sideways to put the video in landscape mode
Townsville Queensland Australia
Native Americans had heavy Neanderthal DNA!
I had heard there was a Neanderthal variant that affected the COVID protein shell weakening it enough to help prevent it from infecting cells with its RNA. Is this true?
Did H Sapiens acquire cold tolerance in crossing with Neanderthals and Denisovan?
Have no idea but I've had a few people comment on how well i handle the cold (I'm Canadian). I don't think it's anything remarkable though and find people's reactions kind of amusing.
Cool thanks
USA. I have 2.2% Nieanderthal DNA according to Natgeo 2.0. Having Covid has been interesting medically for me.
progesterone an enzyme?
Ummm. Yeah...nah. Steroid
How much of the Neanderthal genome survives today in modern humans?
good lecture
Great insight
In fact, we are them. Their genes remain in us. It is a fraction, yes, but we recognized them as human enough to have children with them. The children concidered human.
Everyone just wants to know how the neanertal and denisovan genes exist today effect us today also 2nd would be more about them which is the same thing really - them in relation to us now.
a psychiatrist was telling us about this genome that they have got into now. so he found it interesting. it is interesting. they foun
d things out with this stuff. and found out about groups that were there that are blended in now with others.
We have the rare georgraphic tongue. And we have relation to mongolia some 1/4 so that's more influenced by neanderthal. red hair the one grandmother had red hair when she was young we were told. so that's neandertal trait but then they said that the red hair now isn't neandertal.
This one man's wife wanted to marry him because he was big and looked different. So one of their kids had red hair and her 2 girls had double crowns- cromagnon. He's big, too which they say happens when they interbreed too much. Their kids all looked different some more indian than others. The red hair and light skin's different. The boy had dark hair. The man was white and a big forehead or whatever and that's what happens or something with too much inbreeding. Then some of the men couldn't have kids in neandertals.
I don’t think there were as many Neanderthals running around when Modern Humans reached Asia and Europe as people think
Detroit, Michigan USA
About that gene from the Neanderthals in the 3rd chromosome and the sensitivity to covid. If you take the point of view of China, it is very convenient that the people of european descent and the Indians are more sensitive to the covid because many of them carry the gene and that the Chineses (and the Japaneses and the Coreans) are much less sensitive to Covid because they don't carry that gene. Just thinking...
Makes you wonder………very convenient indeed
were in New York
Yo. Where you at? Is this complex real on the screen?
Yes, the complex is the OIST (Okinawa Institute of Science and Technology Graduate University).
PROVE similarities in genes excludes the possibility of genetic convergence rather than inbreeding.
I'm from Ottawa, Canada's capital city.
And indeed why the interest in Neanderthals .....
Huntington WV
U. S. here. Watching on RUclips. I have Neanderthal DNA. However, I have a chin. Otherwise that's me.
If you really take China at face value. I'd say put a asterisk next to this. For questionable!
Associational data is not conclusive. A scientist should mention that before presenting his hypothesis based on correlation data.
The picture appears to be a Sasquatch
"Covid 19"!? - give me a break please! Is this science or politics?
An advanced CRISPR method.....
The more I learn, the less I know...
It's us who are the brutes.
Just do not! read the printout of Dr. paabo’s talk!
What happened to the Neanderthals - we ATE them!! (poor sods)
The Donner party ate my great great grandma, she fed them fot most of February
He meant the neandethals in the US not us -really
Watched up to 30 minutes
No one talks about how much Neanderthal DNA the Modern Humans already had when they left Africa. You had Neanderthals living in Israel. Israel is not far from Africa
It's Indian national holiday today instead of Columbus day ya
Min 27, chromosomes 3, covid
Now they're trying to destroy the west and our uniqueness
See
Poor quality video, couldn’t read the charts , and the audio would have been better if the speaker would talk directly into mic, but an interesting subject..
Yikes N. didn’t give us a lot of good stuff
Hi dada
America
Blood clots
Being part Neanderthal has turned me into a ninny.
what a ninny goat. . .
I'm glad in not a neanderthal
I still don’t think it’s logical ..not to think humans developed alone on other land masses ...rather than Africa ....surely Asia ....Australia ...pacific islands ...surely the roots cannot just be from the African continent ......I think it’s to easy to think humans did not originate from different places ...understandably evidence is necessary ..... up why not alternative thesis in relation to the traveling of early mankind .....
The Black man is the original man. That's not so hard to believe.
@@Lioness1499 ....well science is showing otherwise ... .not that it really makes much diference ...but scuence is fact based conversation not argument ..
@@rosrebel Science is mankind BS. It has nothing do with Truth. Scientists are mere men trying to figure out creation. So saved the propaganda. It is based on a opinion.
@@rosrebel
L
++!a HD+¹¹¹
Hominids lived in Asia, Africa, and Europe but our ancestors (Homo sapiens) left Africa ~70K.
Nobody knows what's at the north and south poles as evidence where early man came from the climate was different than
u s a
The strong flock expectedly impress because waste psychologically pause toward a troubled certification. fallacious, sticky pressure
I keep rewatching Svante!!.. there’s a good number of lectures on YT.. but this one is RECENT 😱🥰🥰.. I just keep watching and watching!! SOOOOO interesting!!