OIST Foundation
OIST Foundation
  • Видео 24
  • Просмотров 55 709
Artificial Intelligence in Pathology
Advances in digital pathology and artificial intelligence have presented the potential to build assistive tools for objective diagnosis, prognosis and therapeutic-response and resistance prediction. In this talk by OIST Alumnus and Harvard Medical School Assistant Professor Dr. Faisal Mahmood, he discusses: 1) Data-efficient methods for weakly-supervised whole slide classification with examples in cancer diagnosis and subtyping, allograft rejection etc. (Nature Biomedical Engineering, 2021). 2) Harnessing weakly-supervised, fast and data-efficient WSI classification for identifying origins for cancers of unknown primary (Nature, 2021). 3) Discovering integrative histology-genomic prognost...
Просмотров: 564

Видео

Hurricanes in a Warming World - Feat. Dr. Pinaki Chakraborty
Просмотров 4023 года назад
In a groundbreaking article titled, Slower decay of landfalling hurricanes in a warming world, published in Nature on November 11, 2020, Dr. Pinaki Chakraborty at OIST and co-author Lin Li, describe results of their research that suggest that “as the world continues to warm, the destructive power of hurricanes will extend progressively father inland.” This research and its important implication...
Spaces of Innovation: Smart Cities & Innovation Parks from Tsukuba to Okinawa
Просмотров 1173 года назад
The OIST Foundation, in partnership with the Smart City Institute Japan, engaged in a virtual roundtable that discusses the ways in which universities can have a positive impact on local communities and future generations through the formation of innovation parks and smart cities. Panelists: Mr. Takehiko Nagumo, Executive Director, Smart City Institute Japan Dr. Yusuke Mori, Director General, P...
COVID-19 Science Update
Просмотров 1213 года назад
A science update on SARS-CoV-2, the virus that causes COVID-19, by four leading scientists at OIST who have spent the last year engaged in research on various aspects of the virus. The panelists highlight scientific progress and breakthroughs and engage in a conversation on this virus, which has transformed nearly every part of the globe. Presenters include: Dr. Mary Collins, Provost, OIST Dr. ...
Into the Darkness: The Hunt for Forbidden Excitons
Просмотров 7663 года назад
Over the past decade, scientists have seen hints of the behind-the-scenes existence of the forbidden dark excitons, through their effects on their optically active cousins. Recently at OIST, after a many-years-long effort in the development of novel experimental instrumentation, the dark exciton was directly imaged, revealing the surprising dominance of these invisible particles after photoexci...
Mitigating Climate Impact Via Innovation
Просмотров 874 года назад
This webinar focuses on the macro challenge that climate change presents and examines new cutting-edge scientific discoveries to foster resiliency as well as reduce emissions and other causes of climate change and environmental degradation. Panelists include Ms. Naoko Yamazaki, Council Member at The Earthshot Prize and Astronaut (retired) JAXA; Dr. Noriyuki Satoh, Professor, Marine Genomics Uni...
The Future of Oceans in an Era of Climate Change
Просмотров 604 года назад
This webinar focuses on the impact that climate change is having on oceans and marine life and the effects this will have on the U.S., Japan, and the world. Panelists include Dr. Robert Dunbar, Professor, Earth System Science, Stanford University; Dr. Timothy Ravasi, Professor, Marine Climate Change Unit, Okinawa Institute of Science and Technology (OIST), and Dr. Alex Wegmann, Director of Scie...
The Future of Biodiversity in the Pacific Region: Conserving a Threatened Island World
Просмотров 1534 года назад
"Islands” are often compared to the concept of canaries in the coal mine when it comes to climate change. It is on islands that we often see the initial signs of climate change and where it can have rapid impact on biodiversity and signal changes that will soon be coming to other parts of the world. In this webinar, the following panelists explore this topic: Dr. Evan Economo (Professor, Biodiv...
OIST Foundation Overview
Просмотров 2264 года назад
This video is about OIST Foundation Overview
A Campus Like No Other: OIST's Revolutionary Architecture
Просмотров 1854 года назад
A presentation and discussion with two world-renowned architects on 1) the Okinawa Institute of Science and Technology Graduate University’s (OIST) revolutionary elements, 2) OIST’s unique properties, and 3) OIST’s bold challenges. The webinar examines how OIST’s architecture helps promote the twin goals of attracting world-class research to Okinawa and introducing a world-class international r...
The Neanderthals In Us: How Neanderthal Genes Influence Us Today
Просмотров 51 тыс.4 года назад
A presentation by Dr. Svante Pääbo on how genes from Neanderthals still influence us from one of the most outstanding leaders in the field of evolutionary genetics. Dr. Pääbo will discuss how Neanderthal gene variants influence fertility, pain sensitivity and severity of SARS-COV-2 infections in people today. Svante Pääbo is Director, Max Planck Institute for Evolutionary Anthropology & Adjunct...
Oceans, Climate, Cholera, and the Coronavirus
Просмотров 324 года назад
Dr. Rita Colwell, one of the most eminent scientists of our time, shares her insights into global challenges facing the planet today ranging the health of oceans to climate change to disease. In addition, she highlights elements of her new book, A Lab of One’s Own, about the challenges women face in the field of science and how this can be changed. Moderated by Ms. Kathy Matsui. Dr. Rita Colwel...
The Science of Entrepreneurship in Japan
Просмотров 2854 года назад
This webinar is about the challenges and opportunities of being an entrepreneur in Japan, the role of higher education in fostering an innovation ecosystem, and how to deepen U.S.-Japan partnerships to promote entrepreneurship. Moderator Ms. Claire Chino, President & CEO of Itochu International, Inc. (New York) Panelists Dr. Zachary Bell, CEO & Founder, REPS (Okinawa, Japan) Mr. Kenji Govaers, ...
Strengthening Transnational Bonds in the Era of Online Connections
Просмотров 1444 года назад
Strengthening Transnational Bonds in the Era of Online Connections: Research and Educational Exchange in the U.S., Japan, and the Philippines - A Webinar in Partnership with Fulbright Japan, Fulbright Philippines, and the OIST Foundation Aired on June 30, 2020 JST Produced by Fulbright Japan, Fulbright Philippines, and the Okinawa Institute of Science and Technology Foundation (OIST Foundation)...
The Future of Coral: Climate Change and Coral Reefs in the U.S. and Okinawa
Просмотров 1754 года назад
The Future of Coral: Climate Change and Coral Reefs in the U.S. and Okinawa
SAVE OKINAWA WEBINAR 2
Просмотров 304 года назад
SAVE OKINAWA WEBINAR 2
Save Okinawa Concert 2
Просмотров 5974 года назад
Save Okinawa Concert 2
From Okinawa to the Subaru Telescope: Dr. Yuko Kakazu's Journey
Просмотров 2724 года назад
From Okinawa to the Subaru Telescope: Dr. Yuko Kakazu's Journey
Discussion with Violinist Eiko Kano
Просмотров 1444 года назад
Discussion with Violinist Eiko Kano
Webinar featuring Kazuki Sawa, Eiko Kano, and Yuko Kakazu
Просмотров 1704 года назад
Webinar featuring Kazuki Sawa, Eiko Kano, and Yuko Kakazu
Save Okinawa Concert One - Featuring Eiko Kano
Просмотров 1624 года назад
Save Okinawa Concert One - Featuring Eiko Kano
Expedition Japan: Commodore Perry's Hidden Interest in Science Webinar
Просмотров 3044 года назад
Expedition Japan: Commodore Perry's Hidden Interest in Science Webinar
U.S.-Japan Science Webinar Series
Просмотров 194 года назад
U.S.-Japan Science Webinar Series
Global Women in Science: Emerging Voices in U.S.-Japan Relations Webinar
Просмотров 704 года назад
Global Women in Science: Emerging Voices in U.S.-Japan Relations Webinar

Комментарии

  • @Yes-bk9cl
    @Yes-bk9cl 2 месяца назад

    "Covid 19"!? - give me a break please! Is this science or politics?

  • @Ken19700
    @Ken19700 6 месяцев назад

    How much of the Neanderthal genome survives today in modern humans?

  • @ethanoyamawang
    @ethanoyamawang Год назад

    I like the comparison of Okinawa and Hawaii!

  • @TT3TT3
    @TT3TT3 Год назад

    It's us who are the brutes.

  • @nyahanidread4887
    @nyahanidread4887 Год назад

    So the only real 100 % HUMANS living today are Africans .

  • @johnrogan9420
    @johnrogan9420 Год назад

    Not in Africa...probably from a different set of Asian apes.

  • @idaruthjohnson1978
    @idaruthjohnson1978 Год назад

    Listening in Sutter Creek, California.

  • @planmet
    @planmet 2 года назад

    Adding to my comment above - research work has pinpointed genes on chromosome 18q as being the ones that affect skull morphology.

  • @planmet
    @planmet 2 года назад

    It could be due to the different cranial morphology of the neanderthaal - it being more oval - that leads to birthing difficulties and so a premature birth when the skull is smaller would have been an evolutionary adaption to resolve this problem - but of course this would lead to another dilemma - having to cope with a premature baby. It could be that H. sapiens resolved these problems - by a mutation which altered the morphology of the skull - making it more 'vertical' in shape (by vaulting up of the braincase). This would be a successful gene variation as more babies would survive.

  • @auroraasleep
    @auroraasleep 2 года назад

    u s a

  • @suesmothers4225
    @suesmothers4225 2 года назад

    It's Indian national holiday today instead of Columbus day ya

  • @suesmothers4225
    @suesmothers4225 2 года назад

    America

  • @myronsmith2114
    @myronsmith2114 2 года назад

    I don’t think there were as many Neanderthals running around when Modern Humans reached Asia and Europe as people think

  • @myronsmith2114
    @myronsmith2114 2 года назад

    No one talks about how much Neanderthal DNA the Modern Humans already had when they left Africa. You had Neanderthals living in Israel. Israel is not far from Africa

  • @myronsmith2114
    @myronsmith2114 2 года назад

    How do we know if the modern humans that left Africa 70 thousand years ago didn’t already have Neanderthal DNA and the Neanderthals were already wiped out when we got to Asia and Europe . Some modern humans at that time were found with as much as 9 percent Neanderthal DNA

  • @inagordan4589
    @inagordan4589 2 года назад

    were in New York

  • @wangchakip8551
    @wangchakip8551 2 года назад

    congratulation Dr. Svante Pääbo !!!

  • @aexesia
    @aexesia 2 года назад

    The nonsensical theory that there are no neanderthal genes in Africa has been debunked years ago. This is bad science.

  • @h.m.mcgreevy7787
    @h.m.mcgreevy7787 2 года назад

    The more I learn, the less I know...

  • @martylawrence5532
    @martylawrence5532 2 года назад

    What causes adaptations to changed environments? To new diets such as the Darwin Finch encountered on new islands? To new threats such as bacteria encounter with a new antibiotic? This observable evidence is the cornerstone in which the theory of evolution is based. This is called microevolution within the species. It's a step toward macroevolution that transcends the species into new ones such as a land animal evolving into today's whales, as the theory of evolution proposes. By what mechanism? It's DNA mutations getting naturally selected. According to theory, bad mutations are weeded out and beneficial ones are kept thus advancing animals into new ones or adjusting within species in a small microevolution step. This is what the new synthesis of evolution says with the merger of Mendelian genetics with Darwinian evolution that resulted in a unified theory of evolution. It is sometimes referred to as the Neo-Darwinian theory. The Modern Synthesis was developed by a number of now-legendary evolutionary biologists in the 1930s and 1940s. So what really causes adaptations to changed environments? To new diets such as the Darwin Finch encountered on new islands? To new threats such as bacteria encounter with a new antibiotic? In 2014, it was acknowledged for the first time in peer review it is a BUILTIN BIOLOGICAL SYSTEM CALLED THE EPIGENOME. It's already enabled to make these adaptations thru environmental cues coming thru the female eggs and male seminal fluid passed to their new offspring...or with bacteria with new divisions by the epigenetics. New adaptations comes from the same system that gives us gene expression modifications. This is WITHOUT DNA errors but is by largely methylation chemical tagging that turns genes on and off or up and down. Just as a caterpillar makes new structures like wings as the DNA sequences stay the same as it merely modifies its epigenome. It's works like an intelligent software program...not on-the-fly evolutionary theory. Bacteria and viruses adjust their genes to become more resistant to attacks upon them. The ASSUMED evolving of DNA mutations is now falsified. They are mere mutation load that can make differences that are not evolution-pertinent such as...speciation by loss of ability to sire offspring and new trait differences. The beak differences of Darwin Finches had their correlation with epigenetic modification's...NOT with DNA mutations. This was found by Dr. Michael Skinner by his sophisticated scientific method he used. Other species of finches show new beak shapes in experiments with new diets. They pass beak adaptations to their offspring in just SEVENTEEN YEARS...not 2.1 million years as the theory of evolution proposed. Bottom line? Chaos of DNA mutations becoming new evolutionary order is NOT happening. It's absurd comic book science. Adaptations are by the smart-designed epigenome coming as standard equipment. It's Intelligent Design with logistics showing it came about at the moment of creation. The Creator? Jesus Christ. Explore the wonderous new fact for atheists who used ToE as evidence of no God, of the FREE GIFT of eternal life by faith without works. Become a Christian today. Charles Darwin ended up having no answers for you. Jesus does!

  • @kludgedude
    @kludgedude 2 года назад

    Yikes N. didn’t give us a lot of good stuff

  • @hectorlopez4365
    @hectorlopez4365 2 года назад

    I am Puerto Rican with 1% Denisovan,2%Neanderthal,41% Italian,22% Spanish Celtic,17% Midleast, 7% African. Héctor López

  • @duffeymusic9220
    @duffeymusic9220 2 года назад

    USA. I have 2.2% Nieanderthal DNA according to Natgeo 2.0. Having Covid has been interesting medically for me.

  • @jughound7923
    @jughound7923 2 года назад

    If it has a Sloping Forehead and a Mid Tarsal break across the center of Their Feet ? Then They are the Sasquatch People ( no matter what you name them )

  • @gregoryhunt9086
    @gregoryhunt9086 2 года назад

    In fact, we are them. Their genes remain in us. It is a fraction, yes, but we recognized them as human enough to have children with them. The children concidered human.

  • @markissboi3583
    @markissboi3583 2 года назад

    How many seen neverlands in USA :) leave a like and a Sub way

  • @abstractacus1598
    @abstractacus1598 2 года назад

    Why covid higher in europe than africa? Maybe cos theyve been faking the count in europe..

  • @willowgreinke7964
    @willowgreinke7964 2 года назад

    I’m thinking Head Size MUST have been a factor in regards to Homo-Sapiens giving Birth to Neanderthal &/or Denosovian births… where early birth could have been the body’s only chance at both Mother & child staying Alive.

  • @Szymanskill
    @Szymanskill 2 года назад

    Denisovan and Neanderthals have an ape like rib cage, do we know at which point or the cause of the change in modern humans

  • @johnwyatt9155
    @johnwyatt9155 2 года назад

    See

  • @johndavis6119
    @johndavis6119 2 года назад

    I had heard there was a Neanderthal variant that affected the COVID protein shell weakening it enough to help prevent it from infecting cells with its RNA. Is this true?

  • @rajeevdsamuel
    @rajeevdsamuel 2 года назад

    Pure Nonsense - neanderthals looked like orcs and were stupid cannibals.

  • @kevinmoore.7426
    @kevinmoore.7426 2 года назад

    Occipital Bun Neanderthal ?

  • @dinacharlayne1912
    @dinacharlayne1912 2 года назад

    Everyone just wants to know how the neanertal and denisovan genes exist today effect us today also 2nd would be more about them which is the same thing really - them in relation to us now. a psychiatrist was telling us about this genome that they have got into now. so he found it interesting. it is interesting. they foun d things out with this stuff. and found out about groups that were there that are blended in now with others. We have the rare georgraphic tongue. And we have relation to mongolia some 1/4 so that's more influenced by neanderthal. red hair the one grandmother had red hair when she was young we were told. so that's neandertal trait but then they said that the red hair now isn't neandertal. This one man's wife wanted to marry him because he was big and looked different. So one of their kids had red hair and her 2 girls had double crowns- cromagnon. He's big, too which they say happens when they interbreed too much. Their kids all looked different some more indian than others. The red hair and light skin's different. The boy had dark hair. The man was white and a big forehead or whatever and that's what happens or something with too much inbreeding. Then some of the men couldn't have kids in neandertals.

  • @karate4348
    @karate4348 2 года назад

    No surprise whatsoever that modern humans are insensitive (and likely more traumatised and uptightened in freedom and choice re more healthy movement around the planet as well as our own bodies: sex, birth/pregnancy) leading us to feel fear and insecurity and theorize about rather than experience the fuller nature of life experienced by earlier than 'modern' humans. . Look at that neanderthal structure for example of broader pelvic birth opening = relaxed, easier birth + broader chest cavity= deeper breathing= less stress = less build up/damnation of toxins/energies within and less projection of those out onto the environment. Consider and feel the held up full gestalt of nature by trauma generating more trauma in the body as we escape into mind and 'spirit' from one generation to the next.. Observe how more relaxed and literally less 'uptight' the earlier humans look.. more swinging and dancing there likely, slower and stronger.. trusting their own strength and instinct and sensuality more.... more squatting and being with, rather than held in.. less need for differentiation because more was shared sensually, energetically, with sensitivity of feeling and so less words and neurotic detail was needed... It was just known between and not bound up in individual lives... more connections with the nature of everything. Those (neanderthal and other earlier) sensitivities in keeping with nature were put on hold I believe in some kind of 'uptight' abeyance which we see in (introduced, rushed in by?) the 'modern' humans, accelerating markedly as we become more 'numb' and machine like.. creating more tension, more dis ease and more need to 'armour' ourselves towards ourselves! each other and sadly towards the rest of life and we do, with weapons, chemicals, radiation, and genetics etc. I guess this will not last much beyond our projections out from ourselves, forms of machines/numerical/theoretical patterning/genetic/chemical, atomic and whatever those might mean in another 100 years or so. I don't think modern human dna will do us many favours in terms of sharing with other lives on this wonderful planet and especially not in terms of our own longevity across more generations as we grow more like a dis ease ourselves... this mass colon isation we seem to spread through our propensity to traumatise )inflict pain on each other and especially our children and then numb it. Pain is something modern humans can feel... if only we would allow and tend and heal our pain rather than literally bombing each other with it or pretending pain can be made ok by all manner of other sicknesses and addictions.

  • @michaels4255
    @michaels4255 2 года назад

    Starts at the 6:00 mark.

  • @meredithmericle7487
    @meredithmericle7487 2 года назад

    U. S. here. Watching on RUclips. I have Neanderthal DNA. However, I have a chin. Otherwise that's me.

  • @susanlegeza7562
    @susanlegeza7562 2 года назад

    I am a hungarian from Canada

  • @JohnLloydScharf
    @JohnLloydScharf 2 года назад

    PROVE similarities in genes excludes the possibility of genetic convergence rather than inbreeding.

  • @martylawrence5532
    @martylawrence5532 2 года назад

    Sharing gene variants is evolution-impertinent. There are no assumed evolving of DNA mutations in gene expression. Neandertals were 99.84% identical to us in the DNA sequences, thus making them human...not an evolutionary cousin. Watch out for your evolution mentors equating gene expression changes with evolving DNA mutations. It's smoke and mirrors. Evolution is not happening. It never has. Let me demonstrate with the Darwin Finch and their adapted beaks. In 2014, a peer reviewed paper by Michael Skinner found it was epigenetic gene modifications WITHOUT DNA mutations that gave these different beak shapes to the changed diets. Evolutionary biologists have proposed it took 2.3 million years for this finch adaptation to finally come to a finish. However, other finches have been transported to islands with different diet and new beak shapes came up in TWO GENERATIONS by this already existing epigenome that all life has. It gets its cues directly from the environment to chemically tag modify its genes while the all-important DNA sequence is left alone. No evolution this way. This epigenome has an intelligent design signature, not the godless evolution one. Same with Neandertals. Just gene modifications. We are a creation, folks. This is the best scientific explanation you can find on this subject.

  • @beauyerks7413
    @beauyerks7413 2 года назад

    Svante Paabo is one of this generations great creative geniuses

  • @HenrikSahlinPettersen
    @HenrikSahlinPettersen 3 года назад

    Thank you for a great video! For a tutorial on how to do deep learning based segmentation without the need to write any code using only open-source free software, we have recently published an arXiv preprint of this pipeline with a tutorial video here: ruclips.net/video/9dTfUwnL6zY/видео.html The pipeline is especially suited for pathologists who are not programmers and want to do deep segmentation of histopathological whole slide images.

  • @Rico-Suave_
    @Rico-Suave_ 3 года назад

    Watched up to 30 minutes

  • @sunoveristambul
    @sunoveristambul 3 года назад

    Min 27, chromosomes 3, covid

  • @johndodge2188
    @johndodge2188 3 года назад

    Nobody knows what's at the north and south poles as evidence where early man came from the climate was different than

  • @kathieoray2990
    @kathieoray2990 3 года назад

    I'm from Ottawa, Canada's capital city.

  • @kathleenann631
    @kathleenann631 3 года назад

    Thks to U both!!!!! Soooo informative.

  • @user-ed1mj5zk6f
    @user-ed1mj5zk6f 3 года назад

    Very instructive presentation, thank you both very much. I also had a childhood fascination with archeology but life took me somewhere else (but still in biology). Fascinating in it,s deepest meaning; please keep us appraised.

  • @ellenturner5093
    @ellenturner5093 3 года назад

    Ok you lost me at the pain variance. You are equating a small genome to pain and COVID-19. How about the crappie diet we have been eating since the early 1900’s. Remove all grains, seed oils, high oxalates veg and high sugar veg along with all processed foods your pain will go away. Your susceptibility to Covid will be reduced because you’ve reversed your type 2 diabetes which leads to obesity, high blood pressure, heart disease and cancer. You will eliminate all the inflammation in your body so your immune system can sit back and strengthen so you can fight Covid. Eat protein, animal fat, veg and fruit in season not year round. Say goodbye to auto immune disease because if you change your diet it will be put into remission. This guy is a nutss