Thanks man! I’m third year about to start fourth year AI in IM. Any chance you could do a beginner video about putting in orders for the first time in epic or general tips transitioning to intern year responsibilities? Really been enjoying your vids
The type of study is probably not robust enough to sway clinical practice. As you stated the lower correction group seemed generally sicker. There is also a caveat in Na correction in which symptomatic hyponatremia with seizures does need hypertonic boluses to rapidly correct for seizure treatment. Delineating that group would be important as it would be a confounder or effect modifier. Its interesting that outcome of CPM werent so catastrophic but as far I know Id still err on avoiding CPM.
I was wondering if you could make a video on how your process of reading and evaluating scientific papers. I am a 6th year medical student in the EU trying to updated by reading papers
I have a question for you. When you have a case of hyponatremia from severe hyperglycemia (ie. dka) and as you correct the BG, sometimes the Na corrects rapidly. Do we have to worry about that (keeping in mind this is a true hyponatremia and not pseudo like many ppl say but at the same time no hypotonic state was made from the beginning given the hyperglycemia so risk of OD should be low?)?
First of all these papers were published in NEJM Evidence, not NEJM. These studies have significant methodological flaws and their results should be interpreted with caution. I invite you to read two recent manuscripts that review these studies in depth by experts in the field: Sterns RH, Rondon-Berrios H, Adrogué HJ, et al. Treatment Guidelines for Hyponatremia: Stay the Course. Clin J Am Soc Nephrol. 2024;19(1):129-135. doi:10.2215/CJN.0000000000000244 AND Rondon-Berrios H, Sterns RH. Hyponatremia Correction Rates and Mortality: Causality or Epiphenomenon?. Kidney360. 2024;5(4):610-614. doi:10.34067/KID.0000000000000414
Yes please make journal club a thing in ur channel… like weekly or monthly
I'm a medical student in the UK & hope to go into clinical academics - finding the journal club videos really enjoyable and useful! Keep them coming!
Nice review! I always wondered why our nephrologists were so liberal with their sodium correction.
Thanks man! I’m third year about to start fourth year AI in IM. Any chance you could do a beginner video about putting in orders for the first time in epic or general tips transitioning to intern year responsibilities? Really been enjoying your vids
The type of study is probably not robust enough to sway clinical practice. As you stated the lower correction group seemed generally sicker. There is also a caveat in Na correction in which symptomatic hyponatremia with seizures does need hypertonic boluses to rapidly correct for seizure treatment. Delineating that group would be important as it would be a confounder or effect modifier. Its interesting that outcome of CPM werent so catastrophic but as far I know Id still err on avoiding CPM.
I was wondering if you could make a video on how your process of reading and evaluating scientific papers. I am a 6th year medical student in the EU trying to updated by reading papers
Interesting data…thanks for sharing.
I have a question for you. When you have a case of hyponatremia from severe hyperglycemia (ie. dka) and as you correct the BG, sometimes the Na corrects rapidly. Do we have to worry about that (keeping in mind this is a true hyponatremia and not pseudo like many ppl say but at the same time no hypotonic state was made from the beginning given the hyperglycemia so risk of OD should be low?)?
First of all these papers were published in NEJM Evidence, not NEJM. These studies have significant methodological flaws and their results should be interpreted with caution. I invite you to read two recent manuscripts that review these studies in depth by experts in the field: Sterns RH, Rondon-Berrios H, Adrogué HJ, et al. Treatment Guidelines for Hyponatremia: Stay the Course. Clin J Am Soc Nephrol. 2024;19(1):129-135. doi:10.2215/CJN.0000000000000244 AND Rondon-Berrios H, Sterns RH. Hyponatremia Correction Rates and Mortality: Causality or Epiphenomenon?. Kidney360. 2024;5(4):610-614. doi:10.34067/KID.0000000000000414