Here's your visual guide to the new coronavirus variants
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- Опубликовано: 13 июн 2024
- The SARS-CoV-2 coronavirus seems to be suddenly acquiring mutations at a rapid rate. The most worrying variants, first discovered in South Africa and Brazil, increase the virus’s contagiousness and may even help it evade the human immune system. These characteristics are helping the new variants outcompete the original virus, allowing them to spread quickly around the world. Viruses, including SARS-CoV-2, are constantly evolving and acquiring mutations that don’t affect the virus much. The reason public health experts are concerned is that the new mutations improve the virus’s spike protein, which helps the pathogen enter cells and is the target of most vaccines. If the spike protein evolves sufficiently, the virus may eventually be able to reinfect individuals who have already had COVID-19 or been vaccinated against it. But scientists say it will likely be years before the vaccine stops working entirely-if it ever does. In the meantime, social distancing remains the best way to fight the new mutants. After all, the more viruses that exist in the world, the greater the chance that one will evolve a dangerous mutation.In this video, we explain what the new variants actually are, how they arise and spread, and what they could mean for the future of our ability to vaccinate ourselves against the virus.
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At 2:13, the antibodies are represented as binding to the spike proteins via their Fc regions. This representation is upside-down. Antibodies actually bind via their Fab regions, which are at the top of the "Y". "Fab" stands for "fragment antigen-binding".
Makes one doubt the whole video, doesnt it xD
@@SuperSayianRoman2 The video seems to be accurate, aside from that one mistake. However, the video may be misinterpreted to mean that the UK variant, B.1.1.7 or "alpha", has only a single amino acid change compared to the parental strain, N501Y, which stands for the substitution of tyrosine, symbolized as "Y", for asparagine, symbolized as "N", at amino acid position 501 of the protein. N501Y does appear to be the most important mutation in this virus, increasing the binding affinity of the virus to its receptor, but there are actually 17 protein-changing mutations in this virus that distinguish it from the previously-circulating variant. For those people who say that the vaccines create the variants, I would point out that the alpha variant was detected in a sample that was taken in Kent, England, in September, 2020, while the UK did not start vaccinating their population until December 8, 2020.
@@SuperSayianRoman2 no, it doesn't.
Great video, but the narrator's audio is horrible. Sounds badly distorted and hard to understand (compare with the audio from the interviewees).
The speaker's voice lacks the overtones needed to easily discern the language sounds, please give her a better mic!
the wrong end of the antibody is binding
This deserves more views 👍
I felt like that ended on a morbid note that raises fear of what could happen. And wasn't Coronavirus a dangerous mutation of Sars in itself? So we've been through a lot globally as a human species. End note: that scientist said we can put resources toward isolating the viruses that pop up in the future. Also, hopefully we've learned about what a game plan looks like for any forthcoming dangerous viruses. I'm grasping at positives for my psyche danngittt!!!
Good info, appreciated.
Some say that zoonoses have the potential for Covid-19.
So I think the One-Health Policy deserves to be implemented
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Put subtitles in Portuguese. Please! We thank you very much!
Pay thousands for an illustration but use a $15 microphone to record audio... nice.
impolite, mean comment, pretty western.
@@miaomiaochen5310 Playing the race card, are you? *That* is mean.
we are fucked!
Strain B from usa.
Do I Get Corona ?
yes
Beer
So much about recent jabs...pretty much obsolete in the light of this program. Wasted effort and $$.
Not at all. Science will always learn from "not perfect" results and even from "bad" ones. The only way to stay ignorant is not trying anything at all. It is a waste of time to write this type of comments, none of the vaccines is "obsolete", they will have to be adapted to new variants.
3:21 could be. Could be that it's a beneficial mutation independently developed by random at the same time all over the world. Sure.
Or could be that no amount of lockdown actually moves the needle any. That is that effectiveness of lockdowns is approximately 0% in practice.
It was not necessarily a "de novo" mutation reappearing "at the same time all over the world," that's not the main hypothesis AFAIK, but only that some of the same variants have spread faster in different places, even if ultimately monophyletic, which is either assumed or known. That's contrasted with the merely "fingerprint" meaningless mutations, whose frequencies are not related with how infectious the variants are.
That "lockdowns have aproximately 0% effectiveness" is contrary to all established science. The virus spreads from contact. Therefore restricting personal contacts ought to reduce the viral spread. To deny that effective containment of transmission chains work is to deny the germ theory of disease itself.
Obviously, that's not achieved merely by decree, it depends ultimately on what's put into practice, and so just localities having nominally implemented "lockdowns" is no guarantee that what they did was effectively a lockdown, reducing infection chains.
Covid will end up being like the seasonal flu
The next wave of bullshit.