Coronavirus variants: What you need to know
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- Опубликовано: 20 май 2024
- As the global COVID-19 pandemic continues - viral variants have become the latest concern
But variants are complicated. Each one is made up of a collection of mutations, all of which have the potential to change the SARS-CoV-2 virus in unexpected ways.
So what do scientists mean when they talk about variants and what might this mean for the future of the pandemic?
Sign up for the Nature Briefing: An essential round-up of science news, opinion and analysis, free in your inbox every weekday: go.nature.com/371OcVF 
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Once we get to the Sigma variant we're all screwed
No its called sugma
@@mr.mystery6429 sugma nuts son
This is why we are all going to die… 😂🤦♂️
the only thing stronger than sigma is tau, upsilon, phi, chi, psi, and omega.
@@shadownation2410 ignoring your laughing and face palm emoji usage, we will all die eventually, so what actually has changed?
That's the power of nature.. don't challenge Nature
Right. Even natural lab grown viruses.
What we need to know is that we all gonna die anyway.
Dp you believe in the afterlife?
Virus lives but humans die in the end.
hope there would be discussion on the effects of various types of vaccines (mRNA, vector based, and attenuated) on the naturally developed immunity against COVID 19!
There have been conducted a number of studies about this, called hybrid immunity (immunity after an infection plus at least one vaccine), some of them even in the Journal Nature, the producer of this video 😊.
Sitting here waiting to go in and get my vaccination. I'm very nervous. I'm going through these videos to tell myself I'm playing my part in helping
goodluck bro godbless
Are you ok now?
@@selvycgl yes I'm fine thank you! I had such a dead arm and bit of a sore throat for couple days but okay now 😅
Fake
@@BadAtTeaDude 😆 omg thank you this actually gave me a good laugh! By the way I had my second vaccine since and I actually thought for sure I was dying through that first night, the next day I was full of aches but the headache was gone the chills were gone,by the third day I felt better except for my arm which felt like it was hit by a bat and looking red raw for 4 days. I went through it and it was not easy. You make up your own mind like I had to, each to their own
This is like playing the Plague Inc. game.
Yea....
I know, its like the game was about infectious diseases or something
makes you think huh
How about the double mutated variant found in India in March 2021?
Yes, have you listened to Dr. Campbell UK?
Not just double, triple mutations...
It was found in October wasn’t it ?
@Asherah 1147 Believe me they r doing but even the cremation facilities r facing dangers of overheating. Double mutant variant is very dangerous. And, now they have even reported a "Triple mutant" variant which might be even more dangerous
I have seen some very horrifying n chilling images in India esp when Crematoriums r overloaded with deadbodies n Grave yards having no space for deadbodies, some stray dogs biting on half burnt dead bodies after cremation n Doctors appealing with tears to the citizens to stay at home 😢
This is well done. Thank-you.
99% + survivability
Coldflu19
No mask
No shot
TinyHats
BigJuly's
seem like god is playing "plauge Inc"
As always, please take your vitamins, supplements, or eat vitamin rich foods (C, D, L-opti-zinc, and Quercetin -at least one of those four).
I also suggest looking into antimicrobial masks. These can be made with copper, silver, and zinc oxide.
[Oh, and if you happen to get sick or have symptoms of coronavirus-19, then you can eat broccoli to relieve them].
Kool story bro
@@eric-vu1jy thank you.
So far the variants like UK, Brazil P1, & So. African are much worse than the original recipe Covid-19, so the trend is towards worse variants and we have to wonder how much worse they can get. Is there a limit? Will one come along that nixes us on a mass scale?
I wonder about the “mass murder” mutation as well. It could be in India now.
If you deep dive a little you'll find out that the original wuhan strain had lesser viral load and lesser transmissibility. The variants that have evolved now outside of China have higher transmissibility rate without much increase in the fatality rate. This leads to more people contracting the virus at a quicker rate when unlocks happen, leading to a sudden overload on the healthcare system. Much of the deaths are purely being caused due to inadequate medical attention. I feel focus should be on reducing transmissibility through physical means rather than vaccines in countries where there are multiple varients being found. With multiple varients floating in a population there's an increased chance of spike protein mutations over a period of time. This might significantly hamper the effectiveness of vaccines leading to many more waves.
@@swatin91 yes they will create. Many waves keep the immune system in good order
The editor of the video and whoever did the animations did a killer job.
Thanks, for balance it would have been useful to also include US variants in the global map. Also, the interpatient variability in recovery time means that people without reduced immune functions or other health conditions could allow variant mutations to develop. Attributing the potential development of variants to transplant recipients or HIV positive people is neither scientifically accurate or ethically helpful, given the discrimination that already exists to some groups.
Well done
@@rayc1557 The data show China responded pretty well at limiting new infections and spread. Unfortunately, after the first case is found in any other country, that country becomes responsible for how they control, care and manage. Some countries definitely did better than others, showing it could be done, unfortunately the US was not one of these, nor was the UK, and trying to shift the blame helps no-one.
@@rayc1557 I am only looking at mortality data. I am not supporting management in any country including China. How a country manages SARS after the first case is what counts. Your suggestion to blame China for the disaster in the US does not make sense. After the first US case, everything is down to the US for what happened next. Your comment would be like trying to blame California or New York for not controlling these recent variants.
@@susankilleen2011 uvvggggguggggg
@@rayc1557 hug ggg
Thanks Nature for your summary to broad audiences!
Nature says you guys crossed the line. Now I’ll back to teach you a lesson good job nature!!
Can anyone suggest me the platform to create a video like this?.
Question. How do they detect and determine a new covid variant? What differentiates the variants, is it symptoms alone and/or a test, the PCR test?
they will know if its a different kind of covid if its not the same as the original covid
i think
More fake testing
Genome sequencing.
gonna collect them all!
The latest social craze from the Orient.
do you have what it takes?
Lol
ok weeb
Superb vid
Tq
Isn't true that vaccination can help the virus mutate into a new form/variant?
0:50 whats a strain
Aldous Huxley
Servitude
How do all these variants keep popping up. Where are they coming from???
Like constantly you get sun burns frequently and develop melanoma.
Interesting that a 'charge flip' caused increased infection, maybe a complimentary charge interaction with its binding site? The aspartate to glycine one is interesting too...maybe increased conformational flexibility allows for faster/more successful binding? Would be fun to run the simulations on it.
Such testing of G614 when conversion from D614 were performed comparatively early on in the course of the pandemic last year. The 'changeover' to glycine from aspartic acid as the amino acid comprising the shaft of the "spike" conferred profoundly greater flexibility such that the spike had a much lesser tendency to shatter, and also altered the geometric configuration of the spike to a tripodic conformation conferring enhanced strength to the spike, as well. I believe that the D614G mutation emerged first in Italy and Iran and was noticed when the behavior of CoVid-19 disease seemed conspicuously more aggressively transmissive and the pathogenicity of CoVid-19 disease more lethally 'ferocious' in both countries juxtaposed with CoVid-19 disease every elsewhere on the Globe at that time period, Spring 2020 into early Summer 2020. In March 2020, 25% of the cases of CoVid-19 disease in the United States involved virus with the D614G mutation, by May 2020, 75% of the cases in the U.S. involved virus marked by this mutation, I believe. Globally, virus marked with the D614G mutation was predominant shortly thereafter, not just in the U.S. I hope my information here is essentially correct and is helpful.
Could those with vested interests be organising the spread of Covid 19 and all ensuing varients?
Vaccines will aggravate mutations. The vaccinated will still be infected with less severe symptoms. The vaccination roll out will not stop covid transmission. Once vaccinated a person would throw caution to the wind and behave with reckless disregard to covid rules. Can expect more transmission.
"Vaccines will aggravate mutations." I agree, it will force the virus to seek ways to mutate to avoid vaccine induced anti-bodies and that could likely herald a much worse variant than has occurred so far.
Damn you nature.
Time to go to Greenland
Very interesting, informative and worthwhile video. A must see video for everyone.
@@imbackrisenagain130 You don't know what you're talking about. You're obviously a complete ignoramus.
Haha it’s a nice story.
D614G
different vaccines cause more variants
Stop use of electronic cigarette one of the factor
ship it back to South Africa
The Delta variant is another lab design coz the last one wasn't killing fast enuff?
Now its time for Omicron variant :)
It's a bioweapon created in a lab, and is a retrovirus
Just stop moving anywhere for two weeks all around the world. End
Not all county can afford that. If the USA the economic powerhouse can’t contain their citizens for 2 weeks than other countries have no chance
Hope that fellow scientist's are keeping eye on double mutant variant (E484Q & L425R) from India ..its seems we are gonna lead the world in terms of new cases for few weeks now..
Perhaps third wave won't be that unpredictable and vaccination program does achieve its intended goal (although the pace of vaccination is quite lagged here) anyway.. "Let's do all that we can to make the virus endemic" Take care everyone. (We will get out of this.. This scars will guide us forever) let's endure for now.. Take care everyone.
Thanks ..Very nice information
we're up to mu. that makes 12.
Very clear and well presented. Thanks.
If there were a variant of CoV2 that is highly infectious but much less deadly, could that be used to immunize people against the real thing?
This is actually happening! Propaganda video! 35.000 mutants now recorded
Well if this were to happen you wouldn't need to imunise then, you'd just have to catch the disease itself.
But no, vaccines aren't designed to infect you with the full disease they contain a small fraction of the virus that the body can learn from. Straight up injecting the full blown disease into the human body will never be allowed. It's extremely unethical. A vaccine against a disease should be much much safer than the disease itself.
There are attenuated virus vaccines, such as FluMist, which is an intranasal vaccine. Children younger than 2 years old and adults 50 years old and older are not eligible to get the vaccine. Presumably the margin of safety afforded by the attenuation is not adequate in people with immature or declining immune systems. The same type of restriction is likely to prevent a naturally-occurring less-deadly virus from being given to the people who need it the most. I don't think that any attenuated virus vaccines for COVID-19 have even been tested in clinical trials.
Maybe shut down international travel?
Why?
SOLID
New variants is Yahoo Malaysia.
I just wanna express my gratitude to Dr.Ono on RUclips for curing my HSV 1&2. God will bless you Dr Ono
Please turn off the gas
How do we know what these tiny viruses look like? This is important to fighting it.
There are some spectacular devices called "microscopes".
@@savvasf7136 yep just have a COVID infected person touch the funni thingy and boom u see
1st you get one times to infect spread contamination reaction incubation mutatetion developing next level infection by different bactterias to become next mutation changes suit the host virus carrier to begin new infection chain virus changes new different unique symtom require more times of bodyly behavior adaptation defence and attack not the same as every body every time every where...imposible
Delta Omicron.. SWOP THESE LETTERS AROUND...what words can you make = Media Control
Nice and clear, thanks. Question: if the virus had been allowed to spread unchecked (apart from to the sheltered vulnerable) then most people would have been infected and gained immunity (or they already had natural immunity) and after a few weeks the virus would not have been able to spread due to a lack of infectable hosts. Would this scenario have shortened the virus's window of opportunity to mutate?
No, and a great example of this is Brazil, where almost none public policies to contain the virus were taken. Most people should have been infected at least once, nevertheless, every day more deaths are acumulating over there
@ And the P.1 variant seems to have come from Manaus, Brazil, where it's estimated up to 60% of the population was infected.
@@NealeAdams Exactly, and this is suspected to happen because this P1 variant could be able to pass through the immunity generated by the first strand
If every one was vaccinated against Covid 19 the herd immunith would collapse. Thank God not every one will accept the vaccination.
@@annoconnor2735 Huh? You can get herd immunity through vaccination. Herd immunity is when people either got the actual virus OR took the vaccine. Herd immunity means your body knows how to create antibodies specific for this and both the actual disease and the vaccine achieve this result.
Textbook teaches mutations tend to be rare, & deleterious if happened ..... Virus is, virus does.
Thank you for very informative and helpful video. I heard from the news that the mutated Coronavirus was found in Japan last week. I hope that it is a variant of concern.
PROTECTION
I KNOW THE LIES ARE COUNT'ESS, AND THE MASS NEEDS TO WAKE UP BEFORE THE MARK IS GIVING, AND JESUS CHRIST RETURNS IN MY LIFE TIME. THIS IS NO JOKE
JESUS CHRIST IS YOUR ONLY HOPE TO WHAT IS TO COME.
scientists and medically qualified individuals deserve more say in politics because our politicians are obviously not making the right choices
#3:52 #laboratory #work durring #2021 for a #vaccine
You guys forgot the omicron one
I cant wait for Covid Dream Variant
Is the mutation an adaptation as a result of interactions with various immune systems or is it programmed in the d.n.a of the virus. ?
How did the Corona virus develop the ability to infect human tissue , did it evolve, how long did that take and where is the proof or was it through gain of function?
Survival of the fittest. Those with best traits can survive and spread.
Yuri Bezmanov
if these random variants neber came out pf nowhere the pandemic would be Over.
Hello? It’s lies ..you na see???
@@eric-vu1jy wtf
it's barely visible under a scanning electron microscope. Protip no virus has ever been isolated according to koch's postulates. However they CAN do what they call "isolation" which is just looking for reverse transcriptase with no filtering but reverse transcriptase is present even in non viral material. Scanning electron microscopy cannot even tell the difference between a virus, a random particle (since no sample is purified it contains random particles of junk) or an exosome (extracellular vesicle) also the PCR test is not a diagnostic tool and does not test for viruses nor was it designed to diagnose anything. Plus! Every vaccine contains "proprietary ingredients" which are a secret, not listed AND the vaccine companies need not and will not reveal what those are!
My understanding of the mRNA vaccines is that they contain a chemical script, that is transmitted to our cells’ ribosomes, in order to cause the ribosomes to generate spike proteins (the component that the COVID virus uses to penetrate living cells) that are then released into the bloodstream where our bodies are supposed to create antibodies against the spike proteins. So my question is this: Are we to believe that the variants no longer use a spike protein to penetrate cell walls? Or perhaps the spike proteins themselves are the mutated parts of the variants, as unlikely as that seems?
@Buck Rothschild Interesting. Except the “evolution” nonsense.
@Buck Rothschild LOL yourself. Maybe you should look at the math.
@Buck Rothschild For nearly 40 years I designed and wrote complex algorithms and software including adaptive and recursive algorithms. I can tell you this - there’s no way that anything this complex could be generated by chance (and that’s exactly what random mutation is). The “software” in even the simplest DNA is many orders of magnitude more complex.
My first exposure to understanding the impossibility of Darwin’s ideas was reading about Murray Eden and his work at the Wister Institute. My understanding of the complexity of the genome came as a result of looking into the Genome project in the early 90s. Coincidentally, at that time, I happened to be writing complex adaptive programs in a large, commercial relational database environment. I did some rudimentary math at the time that was enough to convince me, although I knew I lacked sufficient background for a rigorous treatment.
Fast forward to 2009 and Stephen Meyer’s “Signature in the Cell.” His treatment of the math there was along the same lines as what I had done more than a decade earlier, but with much more rigour.
Since my career didn’t depend on toeing the party line, I was free to pursue this independently without any skin in the game. Unfortunately, the current scientific hegemony defends Darwinism as if it were a religion, albeit a poor one. An a priori commitment to materialism, probably with the desire to assert absolute autonomy and thus not be beholden to any external morality, is the only motivation for this that makes sense to me.
Real science - good science - follows the evidence wherever it leads.
@Buck Rothschild I asked a simple question. Is it reasonable that the spike protein is the thing that’s mutated? I ask this because of the mechanism of mRNA vaccines. Correct me if I’m wrong, but do they not instruct our ribosomes to create spike proteins so that our bodies will develop antibodies to those proteins? If so, then the antibodies we produce should be effective against variants unless the spike proteins have been reconfigured extensively. Where have I made any claims to expertise? I simply have asked for clarification. Is my understanding amiss somehow?
BTW, an appeal to authority, such as you use, is normally considered a logical fallacy. This is one area - logic - in which I have an extensive background.
@Buck Rothschild How very typical. Don’t address the arguments. Attack the character or credentials of the one who disagrees with you. I happen to agree with your definition of evolution. Yes gene changes happen over time. But random mutation and natural selection cant be the cause. My original intent was to inquire as to why mRNA vaccines would be ineffective against variants. Apparently with all your great education and experience you can’t even answer a simple question. Or you’re too high and mighty to bother with the unwashed The masses are asses, right? Your attitude is precisely why anyone with any sense avoids the sciences like the plague. The hegemony is hidebound, self-serving, conceited and rotten to the core.
Scamdemic19
Tinyhats
BigJuly's
#4:23 #🌐
These new variants are making horror movies look like a comedy show
DOUG IN GODZILLA VS KONG MOVIE
And dow is this for other virusses. Say the flu virus?
new mRNA SARS - organism comes sout of coffee drink in first evolution , only joke !
Milk makes it better. A mutant (not cowant)
Lol some vaccine have worked fine with some disease as measles ( a quick attack by b cells can do the job but it doesn't mean that will always be the case for all diseases) but it will be fallacy that vaccine will work with every disease like covid that produces variants, the vaccine may worsen the situation that's easy to see in many fronts, trauma to cells may cause cancer, everything significant to cell the dna may record as new attachment, weakening of innate defense systems as well as tricking defense systems may trigger productions to attack organs or ignore diseases.y pov.
-
the immune system without vaccine. innate antibodies 100% attacks the virus then alerts so that t cells b cells record its identification for memory and so these adaptive immune system attacks the virus too.
xxx The immune system after vaccine. innate antibodies 50% attacks the virus because the t cells b cells identified it so got to it first hugging the virus thus shielding 50% of innate antibodies from doing contact fully with the virus, if the adaptive antibodies doesn't match the virus exactly then the virus goes through bypassing logically most innate antibodies therefore the virus has better chances of reaching the cell and infecting xxx
So what's the difference between the vaccinated and unvaccinated? Who will have more protection?
The answer of survival is on the cure not vaccination. my pov.
vaccinated or not, the t cells will still identify the virus doesn't it? and the single thing that this vaccine can do is identfying, and csn become outdated then you are left with more garbage and weakening that can lead to more diseases. my pov.
Why are people thinking that vaccines are cure??
Geert Vanden Bossche a Virologist with musch experience has warned of mutations occurring as a result of mass vaccination in a pandemic using just a prophylactic vaccine that does not eliminate infection and transmission. He wrote an open letter to the WHO requesting a scientific debate and also made several videos and interviews to raise alarm and warn of what could be happening from people that have been vaccinated and then shed mutations within the population.
I think it's possible for vaccine-induced immunity to put selective pressure on a virus to evolve so that it evades vaccine-induced immunity, thus leading to vaccine-resistant variants -- but how would natural immunity not cause natural immunity-resistant variants to arise?
He goes against the WHO and Bill Gates agenda of fear lingering and enforced vaccination programs...
Science VS Magik HAHAHAHAHAHA
Sir/ma
M
OVERDOSE
Tinyhats
Biglies
I wish there was a strain that doesn't kill and is very transmissible and we all get vaccines
funny the thumbs up vs thumbs down ratio is nearly the same as the WUHAN covid19 death rate number
2019-NOVEL CORONA VIRUS DISEASE
Scooby Doo variant
Was drinking my coffee......right out the nose. I wasn't ready for this lmao
@@johnsuggs7828 ruh roh Raggy....
Onree rixty recent refficacy ror the raxcines!!!!
#🌐 #🙏
The big question is: Was the virus programmed to develop en evolve in new variants more and more transmisible? The places or areas that were less afected at the begining seem to have been struck by new variants more capable and more able to "be effective" there, like India or Sweden, for example. Is it an "inteligent virus"?
you are behind the times. many people already know that all viruses are invented and adapted to the natural cleansing of the body from wheat protein glue and milk casein. no one has seen viruses live. it's all a lie. turn on the TV to stay smart and calm
@@suthat6444 So, turn on TV to stay informed. Is it a joke? By the way, viruses are never "alive" they are active, and they are not invented, could have been created (by nature) or designed or engineered by humans. Thanks anyway for your clarifying answer
@@jberto8878 Thank you . it was nice to talk to
SPREED
Alpha Beta Charlie Delta Tango epsilon Sponge Bob variant..
Variants all come from testing ground ..cool
Future of the pandemic. :)
Never had a past
In the boxing events of pakyaw and ugas some has no social distancing and others dont ware mask....👏👏👏 AMAZING .
ASMR
Yeah I'm sure they are studying these variants because they need to to make the virus more effective at compromising more people. Human beings are diverse and their genetic information is diverse and redundant it's hard to manufacture a virus with a complete kill rate yet. I and I say yet because scientist are working hard on fixing that problem.
Ummmm nope #NoJab4Me
I'll take #Ivermectin instead thankyou.
#GeneTherapy #EmergencyUseAuthorization
I hope they don't start saying covid-19 you can get it through having sex
Loki Brought me here
lol same
If the virus originated from animal to humans, then animals may also be mutating and also contributing to spread?
Coldflu19
?????
Influenza !!!!!
DRUGS
hi
hi
@@imbackrisenagain130 why are you mean :(
@@emmy4537 ignore him
Amazing how these media sources can still have scientists speak so confidently about their ability to corral disease.
And they don't even mention how close we are to a Time when antibiotics won't work.
Mate, stop showing people how ignorant you are. And I'll tell you a secret - antibiotics are NOT for virus. Quit embarrassing yourself publicly.
Your own ignorance is not a measure of how capable other people may be.
antibiotics kill or suppress bacteria
@@tailises1713 You are the one making false leaps of logic. But you don't know logic. Because you are ignorant of it. I however have taken logic classes at the University level. I have multiple degrees. People with degrees are typically not considered ignorant. Those who call others ignorant typically do not have the ability to assess intelligence or ignorance, but they have a much closer understanding of ignorance.
My comment states media outlets too often are only presenting the ideas of scientists who are hopeful about corralling disease. There are many scientists who are quite fearful about the ability of coronaviruses to continue to evolve into many variants and to be dangerous for many years, even with vaccines.
There are four major types of common cold that have entered humanity. They are all coronaviruses. We do not attempt to corral the common cold with vaccines because of how quickly it mutates. The same is true of this coronavirus.
The reason I put the comment on antibiotics as an add-on comment was it's an additional line of argument against the hopeful messaging being presented by media outlets about science and its approach to medicine. There is great fear among scientists and doctors that very soon antibiotics will not work anymore. There is a race to study other ways to work with microbial disease vectors. Hope and pray I guess.
The ignorant among us, including those who comment in this forum, often have used antibiotics inappropriately. I prefer to avoid them completely.
There is no way to do this comment in a short manner. I know that's the only way ignorant people can understand anything. It cannot be in print. It must be on a video screen and then they will misinterpret it.
Fie, I say.
WUHAN CHINA
I just found two queue cards in my brothers college papers... one says Asymptotomatic La, da La da I'm not sick... turn it over says...No sighs of disease... the other one is an A shaped queue card Atheism 😇☁️... oh god help me NO!!! Turn it over says ... godlessness 🤣🤣🤣🤣 you all are nuts