As a Medical practioneer..I can justify the amount of knowledge provided in such a easy and professional way....I will highly recommend it to my colleague's
I'm still a bio undergrad but some of the best literature I've ever read were from literature reviews in Nature. They're long af but extremely easy to understand a lot of the time, even for people without a lot of prior knowledge about these things
If all medical books were replaced by animations like these, medical studies would be less boring, more easy to understand and remember and more attractive.
Remember, medical doctors aren't scientists. Research on cancer and possible treatments are done by biochemists, oncologists...human biology/biochemistry is really hard. Harder than any other disciplines.
The problem is that the animations are limited; Many times what is written in medical books, comes from the direct experience of those who have seen the complexities of tissues. In half paragraph describe more than this animation in 5 minutes, can not do.
Thank you so much Nature video. Greetings from Molecular Biology, enviromental and Cancer Research Group (BIMAC) and Bioengineering graduate studies at Universidad del Cauca, Colombia.
Life saver. I have to give a trial lecture on lung cancer and the immune system as part of my PhD defence. This video helped me understand all therapies thereafter. Thank you. Please accept one of my papers for publishing :)
i cant believe im going to be working with postdocs on cancer research and therapeutics for my research lab placement in my final year of college as a molecular bioscience student! this was really helpful thank you
Imagine creating a video game for middle/high school students like the one shown in the video. Science integration in animations and games is truly an effective way to boost ones understanding of the concept!
@@erenyalcn9393 Haha. It is funny how fake media news fucked up your brain, what a racist. Do we need to talk about how is your religion just about sex "Christianity" (If you were a Christian), adultery, gay etc... Pfft
No one ever talks about induced Innate Immunity and the interactions of Dendritic Cells, NK Cells, and Macrocytes. We all catch 1 million cancers every day but the cell receptors of these detect them and destroy the malignant cell. So eat your fruits and vegetables, exercise, maintain a slim weight, and avoid excessive alcohol! BTW, I love to create this type animation as a hobby and this one is especially beautiful. And Parham The Immune System is a wonderful book. When I went to med school I was taught things like "somehow muscles contract" and "somehow infections are controlled" but now it seems every step in every signaling pathway has been figured out. It is incredible (and so exciting) how much is now known about the immune system and all the new practical applications of that knowledge!
Remember, NK cells and their ability to sense stress-associated molecules came about by chance, as did helper T cells, dendritic cells, cytotoxic T cells, coreceptors, perforin and granzymes. Their obvious design wasn't designed. Never mind the effectively infinite permutations of a string of amino acids that had to be searched to find functional proteins.
Hare Kṛṣṇa Toward the scientific case for Intelligent Design (in Biology), a presentation from Discovery Institute Founder, Professor Phillip E. Johnson ruclips.net/video/FDbSNKdTyZs/видео.html Hare Rāma
it's not your body per se. It's which genes you happen to possess and how those genes are expressed. More DNA screening and more specifically single cell RNA seq. should be used to compare treatment options before anyone spends their life savings on it.
@@drekson23 they survive because of either surgery or medical assistance. The body recovers on its own OR the tumor is removed surgically. There has not been a cure for cancer, yet.
After the third chemotherapy session, he stopped eating due to severe mouth ulcers and was hospitalized again. Though stable initially, his condition worsened, leading to organ failure. Despite being on life support, he passed away the following day. I share this to urge others in similar situations to be extremely vigilant.
Can I use a short clip of this for our project promotion video? The clip would be used to illustrate how skin tumor grows and the video is for iGem competition. Thank you very much for considering our request. We look forward to hearing from you.
nice video but some of the information provided are missleading/wrong IL-2 and IFN-a are not efficient therapeutic targets because: 1) IL-2 will also promote the expansion of Tregs leading to immunosuppresion and cancer progression 2) IFN-a could promote lupus-like syptoms
If animation replace all written information then human being will reach to next level because then normal person can understand so much and prohibit any disease by knowing it's symptoms and can seek best medical care
And after five year also treatment has same status. No progress while we fight for COVID but cancer patients die of lack of available treatment. Specially patients with ALK Negative and PDL1 Negative.
Great video, although background music is too loud for me to fully listen and concentrate to the subject. Especially, when English is not the native language.
I really loved the video; and in addition, some other mechanisms of immune evasion by tomours would be the loose of the MHC 1 expression so that cell can not be detected by the lymphocyte T, but that can be helpulf for the cells NK to detected tose cells without MHC1. I'm surprised of how tomours can do the same mechanism as the Immune-privileged tissues, so they can decreased or stop the inmune response. And the inmunotherapy is like a way to potencial the functions of the T cells, so they can continue their work.
it may be that using tatooing to administer site specific medicine in the case of skin related issues such as melanoma will be found to reduce the effect of such medication on other parts of the body. another possible treatment for melanoma may be cauterization, which has been used by Arab communities to this day for other issues with some similarity to acupuncture. very little research is available on Arab medicine at this time.
Imo immunotherapy, especially the therapies focusing on killer T cells specific to the patients cancer, just may be the silver bullet we've been waiting for in the cure for cancer
@@solidfuel0 Yes but still it can kills healthy cells and in some cases patients developed an autoimmune response. We need to increase the specificity furthermore.
@@FKGZ7 there will never be a cure for "cancer" cancer is a wide variety of genetic diseases.There will never be one thing that will cure all forms of cancer
is immuno therophy works on brain tumor..that to pilocytic astrocytoma tumor ..my 5yrs child had that tumor..surgery,radio therophy. .chemotherapy all r failed to cure the disease.
![Noob To Max With DRAGON REWORK In Blox Fruits [FULL MOVIE]](http://i.ytimg.com/vi/LnBMOinoOvA/mqdefault.jpg)
As a Medical practioneer..I can justify the amount of knowledge provided in such a easy and professional way....I will highly recommend it to my colleague's
I'm still a bio undergrad but some of the best literature I've ever read were from literature reviews in Nature. They're long af but extremely easy to understand a lot of the time, even for people without a lot of prior knowledge about these things
it's incredible how well it's animated and how concise and instructful it is!
@@noname8354Narrative reviews are very good for basic sciences
As a practicing oncologist I must say this is by far the most easy and great animation on Immunotherapy I have watched.
Thanks for your work!
If all medical books were replaced by animations like these, medical studies would be less boring, more easy to understand and remember and more attractive.
You still need books.
@tractor Wrong.
@tractor pathology: excuse me wtf!
Remember, medical doctors aren't scientists. Research on cancer and possible treatments are done by biochemists, oncologists...human biology/biochemistry is really hard. Harder than any other disciplines.
The problem is that the animations are limited; Many times what is written in medical books, comes from the direct experience of those who have seen the complexities of tissues. In half paragraph describe more than this animation in 5 minutes, can not do.
I’m a doctoral student in Molecular Biology, and these animations are beautiful! I’ll be sure to use these with my classes!
Awesome video, I really wish there were more animated videos like this one, that they were longer and more in-depth.
I agree
Its resl life.
Look up nucleus medical media.
melanocytes
keep looking... keep finding... don't give up hope.
Fascinating video.
My only comment: someone should actually make that cancer-fighting version of "Space Invaders".
😅😅
Exactly! 😂
I have a game called "Fungalinvaders" that already goes into that direction (as the name suggests, you fight fungi). But it's a shitty game
Dr. Mario
Good idea, I'll get on it
This is definitely the best video I watched in all my medicine studies.
Thank you so much Nature video. Greetings from Molecular Biology, enviromental and Cancer Research Group (BIMAC) and Bioengineering graduate studies at Universidad del Cauca, Colombia.
Thanks for the video and we pray to God to heal all the sick
Agobebjalo🙏
Life saver. I have to give a trial lecture on lung cancer and the immune system as part of my PhD defence. This video helped me understand all therapies thereafter. Thank you. Please accept one of my papers for publishing :)
How did it go? And a very big thanks for your research on those subjects!
@@MegaSantiago20 it went super well - if I remember. Was a fun day. Passed so all good
@@data790 Awesome!
i cant believe im going to be working with postdocs on cancer research and therapeutics for my research lab placement in my final year of college as a molecular bioscience student! this was really helpful thank you
Imagine creating a video game for middle/high school students like the one shown in the video. Science integration in animations and games is truly an effective way to boost ones understanding of the concept!
سبحانك ربي ما أبدعك، وعلم الإنسان ما لم يعلم.
Nice bomb plans
What??? I'm no Arabic, but...
🔠🔡🔢🔤🅰️🆎🅱️🆑🅿️🆔🅱️🆑🆎🅾️🅰️🈁🈂️🈷️🈶🈯️🉐🈹🈚️🈲🉑🈸🈴🈳㊗️㊙️🈺🈵
ignorant pricks
@@erenyalcn9393 Haha. It is funny how fake media news fucked up your brain, what a racist. Do we need to talk about how is your religion just about sex "Christianity" (If you were a Christian), adultery, gay etc... Pfft
سبحان الخالق ما أروع خلقه!!!
Most interesting topic ever. I wish we could someday replace the chemotherapy/radiation totally with modified immunotherapy.
This video is EPIC! Makes much sense of the long list of names and roles of the non-transformed tumour associated cells!
I think there is a mislabeled point in video at 3:50. It should be labeled in regulatory T cell not Helper T cell.
No one ever talks about induced Innate Immunity and the interactions of Dendritic Cells, NK Cells, and Macrocytes. We all catch 1 million cancers every day but the cell receptors of these detect them and destroy the malignant cell. So eat your fruits and vegetables, exercise, maintain a slim weight, and avoid excessive alcohol! BTW, I love to create this type animation as a hobby and this one is especially beautiful. And Parham The Immune System is a wonderful book. When I went to med school I was taught things like "somehow muscles contract" and "somehow infections are controlled" but now it seems every step in every signaling pathway has been figured out. It is incredible (and so exciting) how much is now known about the immune system and all the new practical applications of that knowledge!
Nk cell is my spirit animal
As medical students this great technology that our ancestors have not seen it before
Remember, NK cells and their ability to sense stress-associated molecules came about by chance, as did helper T cells, dendritic cells, cytotoxic T cells, coreceptors, perforin and granzymes. Their obvious design wasn't designed. Never mind the effectively infinite permutations of a string of amino acids that had to be searched to find functional proteins.
Hare Kṛṣṇa
Toward the scientific case for Intelligent Design (in Biology), a presentation from Discovery Institute Founder, Professor Phillip E. Johnson
ruclips.net/video/FDbSNKdTyZs/видео.html
Hare Rāma
Came about by chance?
Balderdash!!!
Yeah, it's pretty far fetched, @@brightobi5361.
I don’t believe Creationist Believers in Intelligent Design would agree 🫶🏼 🌸 🫶🏼 🌸 🫶🏼
Very good, @@Jesus_Resurrection_and_Life.
Love that space invaders animation
Each individual's body reaction to medicine and therapy are different. a patient has to try and find the right medicine or combination for the body.
it's not your body per se. It's which genes you happen to possess and how those genes are expressed. More DNA screening and more specifically single cell RNA seq. should be used to compare treatment options before anyone spends their life savings on it.
So how about those cancer survivors?
@@drekson23 good point, the best point actually !
@@drekson23 Good point, the best point actually !
@@drekson23 they survive because of either surgery or medical assistance. The body recovers on its own OR the tumor is removed surgically. There has not been a cure for cancer, yet.
After the third chemotherapy session, he stopped eating due to severe mouth ulcers and was hospitalized again. Though stable initially, his condition worsened, leading to organ failure. Despite being on life support, he passed away the following day. I share this to urge others in similar situations to be extremely vigilant.
This animation is so cool
Fantastic graphics ! Great job Nucleus Medical Media.
I love the immunity so much ❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️
thank you for this video. my genetics teacher made things more complicated than they have to be. this video makes visualizing what happens easier.
I agree completely
Can I use a short clip of this for our project promotion video? The clip would be used to illustrate how skin tumor grows and the video is for iGem competition. Thank you very much for considering our request. We look forward to hearing from you.
It brought me more closer towards science.Please keep it up
The best animation that I have ever seen.Good job
As a smoker I needed to know this. Thanks
!!! *PLEASE ADD THE KOREAN SUBTITLES I MADE* !!! (There are parts that are translated liberally)
One of the best videos about inmune system our there.
How is the immune response from the macrophages against the tumoral cells?
@bietoff0728 Wth.. Is this spam?
@bietoff0728 Another mindwashing "expert"
@bietoff0728 Enough to know that homeopatics and herbal treatments for diseases like cancer are a dangerous game, because of which people die.
Thank you for this very carefully and clearly thought out video.
nice video but some of the information provided are missleading/wrong
IL-2 and IFN-a are not efficient therapeutic targets because:
1) IL-2 will also promote the expansion of Tregs leading to immunosuppresion and cancer progression
2) IFN-a could promote lupus-like syptoms
CD8 T cell's mediated cytotoxicity scene was amazing
I'm not in health science but I'm enjoying this insightful presentation tremendously
I was amazed by the quality of the animation and the concept of immunoediting.
This channel deserves more subscribers because of its creativity and hardworkship on this fascinating animation video
Well done😊😊😊
I really liked this video. PLEASE make one describing oncolytic immunotherapies such as T-VEC!
Animations are purely effective.
Is there a way to get rid of the background music? Or another version without it?
Thank you Nature
Amazinggggg! Thank you for the amazing and concise and clear and fun animation
Hello my friend, may I ask if your company needs anti-cancer drugs-
(Including formula, raw materials, semi-finished products)? I am from China.
Amazing video. Spending all efforts and great technology to make this video clear and more more easy to understand. Thank you
If animation replace all written information then human being will reach to next level because then normal person can understand so much and prohibit any disease by knowing it's symptoms and can seek best medical care
Really helped me understand how the treatment helps. Thank you.
Beautiful presentation. Thank you.
Great video,Great explanation!
Will this be available to regular humans?
And after five year also treatment has same status. No progress while we fight for COVID but cancer patients die of lack of available treatment. Specially patients with ALK Negative and PDL1 Negative.
Animations always make it look so easy.
Great video about inmune response
what is the microscope used in this video ????
Great video, although background music is too loud for me to fully listen and concentrate to the subject. Especially, when English is not the native language.
Get rid of background noise!
possible cutting off the afferent supply of blood to tumor or rogue vein
Good animation.obstract special liy????? immunology.
Can I use this video with Nature Video credentials mention for teaching?
Ruisantos
thank you for this video
I really loved the video; and in addition, some other mechanisms of immune evasion by tomours would be the loose of the MHC 1 expression so that cell can not be detected by the lymphocyte T, but that can be helpulf for the cells NK to detected tose cells without MHC1. I'm surprised of how tomours can do the same mechanism as the Immune-privileged tissues, so they can decreased or stop the inmune response. And the inmunotherapy is like a way to potencial the functions of the T cells, so they can continue their work.
thanks so much! very helpful
THE future of cancer treatments alongside TIL. Keep discovering!
Can anyone share the link to the background music? What a fascinating musical score?
thank you for a nice video. can I ask how can I make such video. what tools did you use ?
it may be that using tatooing to administer site specific medicine in the case of skin related issues such as melanoma will be found to reduce the effect of such medication on other parts of the body. another possible treatment for melanoma may be cauterization, which has been used by Arab communities to this day for other issues with some similarity to acupuncture. very little research is available on Arab medicine at this time.
This helped a tremendous amount for my presentation. Thank you.
I am wondering is this the good cells?
This is great!!
What if nk2 cells increase the reverse case
Such an amazing video!!! So much better than any textbook I’ve read
Why the hell is music sooo loud i can't hear the lecture man
Thanks for your clear explanations, Many thanks
Question is how tumours can use those small PDL connections and such outta nowhere, as if Tumors were intended when they're bad, feels weird to me
Thank you for the video. Why do we need the imitation music in the background?
Immunology is very important..
me encanta esta explicación para mejorar el conocimiento y razonamiento futuros
Fantastic video here.
Imo immunotherapy, especially the therapies focusing on killer T cells specific to the patients cancer, just may be the silver bullet we've been waiting for in the cure for cancer
If we can eliminate or reduce the side effects then probably yes
@@FKGZ7 what side effects? I thought it's better than chimo
@@solidfuel0 Yes but still it can kills healthy cells and in some cases patients developed an autoimmune response. We need to increase the specificity furthermore.
@@FKGZ7 there will never be a cure for "cancer" cancer is a wide variety of genetic diseases.There will never be one thing that will cure all forms of cancer
I also think the Immune System it is the cure for cancer so what we all have to do is keep boosting the Immune System and stay healthy all the time.
Many thanks for this very informative video
Combining checkpoint inhibitors with different action is a good idea as well.
VERY GOOD VERY USEFUL
Hehe, here’s a like for the Space Invaders reference. Whoever made this had a sense of humor.
Sir i have a tumor in my finger though it very small but its very painful i want to know how and where can i go to seek this immunotherepy
there is a different type of immunotherapy that. block the cd 47, and uses the macrophages instead of t cell to fight the cancer.
Fantastic animation!! Thank you
is immuno therophy works on brain tumor..that to pilocytic astrocytoma tumor ..my 5yrs child had that tumor..surgery,radio therophy. .chemotherapy all r failed to cure the disease.
4life Research have been doing their research on this 50 years ago.
Does immunotherapy work for every cancer ,
Me encantaría, si pueden traducirlo al español!!!
Gracias
Totally awesome animation video. Thank you. Can we have more please?
this animation is great
Me: WHAT THE FUCK HE TALKING ABOUT??
2:45
Me: I see, now I understand
This is so moving ❤️
Great video👌👌
What a nice video thanks ...
beautiful! Thank you from Brazil!