Tumour immunology and immunotherapy
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- Опубликовано: 16 сен 2015
- This animation created by Nature Reviews Cancer and Nature Reviews Immunology illustrates how tumour cells are sensed and destroyed by cells of the immune system and how tumours can evolve to evade immune-mediated elimination. Scientists are developing new immunotherapies that help the immune system to ‘fight back’ - the animation explains how these exciting new drugs work.
Nature has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
See also: Nature Reviews Drug Discovery collection on Cancer immunotherapy: www.nature.com/nrd/collections...
Further reading: Focus on Tumour immunology & immunotherapy: www.nature.com/reviews/focus/t...
Sign up for the Nature Briefing: An essential round-up of science news, opinion and analysis, free in your inbox every weekday. go.nature.com/371OcVF 
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As a Medical practioneer..I can justify the amount of knowledge provided in such a easy and professional way....I will highly recommend it to my colleague's
I'm still a bio undergrad but some of the best literature I've ever read were from literature reviews in Nature. They're long af but extremely easy to understand a lot of the time, even for people without a lot of prior knowledge about these things
it's incredible how well it's animated and how concise and instructful it is!
@@noname8354Narrative reviews are very good for basic sciences
If all medical books were replaced by animations like these, medical studies would be less boring, more easy to understand and remember and more attractive.
You still need books.
@tractor Wrong.
@tractor pathology: excuse me wtf!
Remember, medical doctors aren't scientists. Research on cancer and possible treatments are done by biochemists, oncologists...human biology/biochemistry is really hard. Harder than any other disciplines.
The problem is that the animations are limited; Many times what is written in medical books, comes from the direct experience of those who have seen the complexities of tissues. In half paragraph describe more than this animation in 5 minutes, can not do.
Awesome video, I really wish there were more animated videos like this one, that they were longer and more in-depth.
I agree
Its resl life.
Look up nucleus medical media.
melanocytes
I’m a doctoral student in Molecular Biology, and these animations are beautiful! I’ll be sure to use these with my classes!
Fascinating video.
My only comment: someone should actually make that cancer-fighting version of "Space Invaders".
😅😅
Exactly! 😂
I have a game called "Fungalinvaders" that already goes into that direction (as the name suggests, you fight fungi). But it's a shitty game
Dr. Mario
Good idea, I'll get on it
This video is EPIC! Makes much sense of the long list of names and roles of the non-transformed tumour associated cells!
This is definitely the best video I watched in all my medicine studies.
keep looking... keep finding... don't give up hope.
As a practicing oncologist I must say this is by far the most easy and great animation on Immunotherapy I have watched.
Thanks for your work!
i cant believe im going to be working with postdocs on cancer research and therapeutics for my research lab placement in my final year of college as a molecular bioscience student! this was really helpful thank you
Thank you for this very carefully and clearly thought out video.
This helped a tremendous amount for my presentation. Thank you.
Really helped me understand how the treatment helps. Thank you.
I was amazed by the quality of the animation and the concept of immunoediting.
It brought me more closer towards science.Please keep it up
Fantastic graphics ! Great job Nucleus Medical Media.
This channel deserves more subscribers because of its creativity and hardworkship on this fascinating animation video
Well done😊😊😊
Thanks for your clear explanations, Many thanks
Thanks for the video and we pray to God to heal all the sick
Agobebjalo🙏
No one ever talks about induced Innate Immunity and the interactions of Dendritic Cells, NK Cells, and Macrocytes. We all catch 1 million cancers every day but the cell receptors of these detect them and destroy the malignant cell. So eat your fruits and vegetables, exercise, maintain a slim weight, and avoid excessive alcohol! BTW, I love to create this type animation as a hobby and this one is especially beautiful. And Parham The Immune System is a wonderful book. When I went to med school I was taught things like "somehow muscles contract" and "somehow infections are controlled" but now it seems every step in every signaling pathway has been figured out. It is incredible (and so exciting) how much is now known about the immune system and all the new practical applications of that knowledge!
Love that space invaders animation
The best animation that I have ever seen.Good job
Thank you so much Nature video. Greetings from Molecular Biology, enviromental and Cancer Research Group (BIMAC) and Bioengineering graduate studies at Universidad del Cauca, Colombia.
I really liked this video. PLEASE make one describing oncolytic immunotherapies such as T-VEC!
beautiful! Thank you from Brazil!
Amazing video. Spending all efforts and great technology to make this video clear and more more easy to understand. Thank you
This animation is so cool
Beautiful presentation. Thank you.
Animations always make it look so easy.
سبحانك ربي ما أبدعك، وعلم الإنسان ما لم يعلم.
Nice bomb plans
What??? I'm no Arabic, but...
🔠🔡🔢🔤🅰️🆎🅱️🆑🅿️🆔🅱️🆑🆎🅾️🅰️🈁🈂️🈷️🈶🈯️🉐🈹🈚️🈲🉑🈸🈴🈳㊗️㊙️🈺🈵
ignorant pricks
@@erenyalcn9393 Haha. It is funny how fake media news fucked up your brain, what a racist. Do we need to talk about how is your religion just about sex "Christianity" (If you were a Christian), adultery, gay etc... Pfft
سبحان الخالق ما أروع خلقه!!!
Nk cell is my spirit animal
Life saver. I have to give a trial lecture on lung cancer and the immune system as part of my PhD defence. This video helped me understand all therapies thereafter. Thank you. Please accept one of my papers for publishing :)
How did it go? And a very big thanks for your research on those subjects!
@@MegaSantiago20 it went super well - if I remember. Was a fun day. Passed so all good
@@data790 Awesome!
One of the best videos about inmune system our there.
Such an amazing video!!! So much better than any textbook I’ve read
Imagine creating a video game for middle/high school students like the one shown in the video. Science integration in animations and games is truly an effective way to boost ones understanding of the concept!
Amazinggggg! Thank you for the amazing and concise and clear and fun animation
Totally awesome animation video. Thank you. Can we have more please?
I'm not in health science but I'm enjoying this insightful presentation tremendously
Most interesting topic ever. I wish we could someday replace the chemotherapy/radiation totally with modified immunotherapy.
Chemo drugs come from the Perrywinkle/Vinca plant... God gave us everything we need in the form of plants and weeds.
Many thanks for this very informative video
Great video,Great explanation!
thanks so much! very helpful
PERFECT
Remember, NK cells and their ability to sense stress-associated molecules came about by chance, as did helper T cells, dendritic cells, cytotoxic T cells, coreceptors, perforin and granzymes. Their obvious design wasn't designed. Never mind the effectively infinite permutations of a string of amino acids that had to be searched to find functional proteins.
Hare Kṛṣṇa
Toward the scientific case for Intelligent Design (in Biology), a presentation from Discovery Institute Founder, Professor Phillip E. Johnson
ruclips.net/video/FDbSNKdTyZs/видео.html
Hare Rāma
Came about by chance?
Balderdash!!!
Yeah, it's pretty far fetched, @@brightobi5361.
I don’t believe Creationist Believers in Intelligent Design would agree 🫶🏼 🌸 🫶🏼 🌸 🫶🏼
Very good, @@Jesus_Resurrection_and_Life.
Fantastic animation!! Thank you
Thank you Nature
thank you for this video. my genetics teacher made things more complicated than they have to be. this video makes visualizing what happens easier.
I agree completely
Me encantaría, si pueden traducirlo al español!!!
Gracias
Thank you for this awesome vedio ..it's very informative and easy to graspe
THE future of cancer treatments alongside TIL. Keep discovering!
me encanta esta explicación para mejorar el conocimiento y razonamiento futuros
As a smoker I needed to know this. Thanks
CD8 T cell's mediated cytotoxicity scene was amazing
This is so moving ❤️
This is great!!
Fantastic video here.
thank you for this video
Thank you
amazing contents and presentation, thanks
nice video but some of the information provided are missleading/wrong
IL-2 and IFN-a are not efficient therapeutic targets because:
1) IL-2 will also promote the expansion of Tregs leading to immunosuppresion and cancer progression
2) IFN-a could promote lupus-like syptoms
I love the immunity so much ❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️
Great video about inmune response
Animations are purely effective.
If animation replace all written information then human being will reach to next level because then normal person can understand so much and prohibit any disease by knowing it's symptoms and can seek best medical care
Each individual's body reaction to medicine and therapy are different. a patient has to try and find the right medicine or combination for the body.
it's not your body per se. It's which genes you happen to possess and how those genes are expressed. More DNA screening and more specifically single cell RNA seq. should be used to compare treatment options before anyone spends their life savings on it.
So how about those cancer survivors?
@@drekson23 good point, the best point actually !
@@drekson23 Good point, the best point actually !
@@drekson23 they survive because of either surgery or medical assistance. The body recovers on its own OR the tumor is removed surgically. There has not been a cure for cancer, yet.
thanks
Thank you for the video. Why do we need the imitation music in the background?
Nice animation with clear points
I think there is a mislabeled point in video at 3:50. It should be labeled in regulatory T cell not Helper T cell.
What a nice video thanks ...
this animation is great
thank you for a nice video. can I ask how can I make such video. what tools did you use ?
there is a different type of immunotherapy that. block the cd 47, and uses the macrophages instead of t cell to fight the cancer.
I hope and pray.
Immunology is very important..
Very informative
As medical students this great technology that our ancestors have not seen it before
4life Research have been doing their research on this 50 years ago.
Combining checkpoint inhibitors with different action is a good idea as well.
Can anyone share the link to the background music? What a fascinating musical score?
So many abbreviations in this vid.
Nicely explained
Great video, although background music is too loud for me to fully listen and concentrate to the subject. Especially, when English is not the native language.
!!! *PLEASE ADD THE KOREAN SUBTITLES I MADE* !!! (There are parts that are translated liberally)
Hehe, here’s a like for the Space Invaders reference. Whoever made this had a sense of humor.
Thanks for the chinese subs it was very useful..
Very interesting!
太好了。谢谢
it may be that using tatooing to administer site specific medicine in the case of skin related issues such as melanoma will be found to reduce the effect of such medication on other parts of the body. another possible treatment for melanoma may be cauterization, which has been used by Arab communities to this day for other issues with some similarity to acupuncture. very little research is available on Arab medicine at this time.
Thanks for sharing
VERY GOOD VERY USEFUL
cd 47 therapy combined with the available immunotherapy can help more and more people with cancer.
Excellent
Is there a way to get rid of the background music? Or another version without it?
How is the immune response from the macrophages against the tumoral cells?
@bietoff0728 Wth.. Is this spam?
@bietoff0728 Another mindwashing "expert"
@bietoff0728 Enough to know that homeopatics and herbal treatments for diseases like cancer are a dangerous game, because of which people die.
Can I use this video with Nature Video credentials mention for teaching?
Ruisantos
Good animation.obstract special liy????? immunology.
Get rid of background noise!
And after five year also treatment has same status. No progress while we fight for COVID but cancer patients die of lack of available treatment. Specially patients with ALK Negative and PDL1 Negative.
سبحان الله الذي خلق فأبدع