21.7 Malonic Ester Synthesis and Acetoacetic Ester Synthesis | Organic Chemistry

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  • Опубликовано: 2 ноя 2024

Комментарии • 17

  • @MaturinTurtle19
    @MaturinTurtle19 6 месяцев назад +2

    This is the best explanation and comparison of these processes that I've found, as usual. Thank you, Chad!

    • @ChadsPrep
      @ChadsPrep  6 месяцев назад

      You're welcome and Thank You!

  • @sunilthapa1539
    @sunilthapa1539 2 года назад +1

    your explanations are always through and incredibly comprehensive!!

    • @ChadsPrep
      @ChadsPrep  2 года назад

      Glad you think so - Thanks!

  • @mandarin42
    @mandarin42 3 года назад +3

    This was amazingly helpful in comparing/contrasting these processes - thank you!!

    • @ChadsPrep
      @ChadsPrep  3 года назад

      You're welcome, Amanda - glad it helped!

  • @chibichan1791
    @chibichan1791 Год назад

    thank u so much sir, you are honestly the best teacher out there..

    • @ChadsPrep
      @ChadsPrep  Год назад

      Thanks! Great to have you here :)

  • @BruceWayne-i2n
    @BruceWayne-i2n 9 месяцев назад

    Awesome vid and so thankful that this is available.
    Just a quick question - when at 2:30 we say that the carboxylic acid on the right is unstable - is it also fair to say that it's a strong acid (so reactive/unstable) as a result of the Beta carbonyl being electron withdrawing? Or is it specifically because of that kinda ring formation that gets made.

    • @ChadsPrep
      @ChadsPrep  9 месяцев назад +1

      The lack of stability is referring to the fact that beta keto acids (with the C=O on the beta carbon) break down readily in heat in comparison to other carboxylic acids. The reason for this is that we form the cyclic concerted transition state as a result of the H being spatially close to the carbonyl as mentioned. You could think of the beta carbonyl as being withdrawing as the electrons are moving in that direction in the mechanism of the reaction, but it is a part of the bigger picture.

  • @jal4science573
    @jal4science573 2 года назад

    For the malonic ester synthesis, what is the in-depth reason why we need to use NaOEt? If we hydrolyze the esters, does it matter if they got converted to O=C-OMe esters using NaOMe?

  • @benptasienski9749
    @benptasienski9749 2 года назад

    Great work, Chad!

  • @May-ss5kz
    @May-ss5kz Год назад

    thank you for these videos

  • @cppageantwear12
    @cppageantwear12 2 года назад

    Thank you for making this make sense to me! SOOO helpful!