GHB Dose and Effects - Therapeutic and Recreational use By Dr Jonathan Karro

Dr. Jonathan Karro is an Emergency Physician and Clinical Toxicologist. He is the Clinical Director of Emergency Medicine at St Vincent’s Hospital Melbourne and Honorary Senior Lecturer at the University of Melbourne. Jonathan completed a Sabbatical and Masters in Clinical Toxicology in 2012 working with the Victorian Poisons Information Centre and Austin Toxicology Service. His most significant area of toxicology research has been in the optimal sedation of the agitated/behaviourally disturbed ED patient.
Take-Home Points:
• A dose of 1-3 g of GHB can only be detected in serum for eight hours and in urine for about 12 hours, making allegations of drug-assisted sexual assault problematic.
• Therapeutic uses of GHB include obstetrics, anesthesia, narcolepsy, and opiate/alcohol withdrawal.
• Deaths from GHB use are rare but not unheard of.
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