If anyone needs a mnemonic here's mine: IgG - (General) - Makes up 75% of antibodies, generally distributed throughout blood. Long term immune response. IgA - (Airways) - antibodies found in mucous, nasal cavities, saliva, lungs etc IgM - (Major) largest antibody and first to respond to antigens. Highly effective against viruses. IgE - (Echoo!) - Allergic reactions IgD - (Differentiate) - Helps B cells get activated to differentiate them into plasma and memory B cells
I cannot count the times you've saved my life with your videos. As soon as I start a new course, the first thing i check is if you have videos up on my particular subject, you never fail to deliver. Love your videos, please never stop!!
I AM ALWAYS AMAZED HOW YOU ARTICULATE YOUR EXPLANATION. YOU ARE WONDERFUL IN DELIVERING SCIENTIFIC CONCEPTS. I AM THE HAPPIEST TO FIND YOUR EXPLANATION ON THE YOU TUBE VIDEO. YOU STILL TAKING THE LEAD.
Does an antibody belong on the Cytotoxic-T-Cell there, on the diagram? Isn't that receptor is a generic T-Cell Receptor binding to MHC-I. Thank you for the effort that goes into your presentations, they are world-class.
Just wanted to say thank you for all of your help. Your explanations make so much more sense than a book. Also what the heck is your IQ? You look very young for being able to lecture on so many topics. But I am so glad you do!!!!! THANK YOU!!!
u r very awesome sir....I'm lucky to having u youtube teacher.........i wish to be a professor like u....thank u so much for ur awesome work for students....
Could you make a video about how immunoglobulins are diverse? Meaning gene recombination with V(D)J segments, P and N nucleotides, and class switching? I think this is a hard antibody concept to grasp and you do an awesome job at teaching!
8:30 Cytotoxic T cells should have T cell receptors, not antibodies. It's true that naive Tc can be activated by antigen-presenting cells that are infected (e.g. Dendritic cells), but this has nothing to do with antibodies. However, B cells have antibodies as receptors, a.k.a. BCR.
Thanks for your wonderful videos..u are rrally saving me..struggeling with i guess the worst biochem book (is basis for exam) written ever which makes simple things sooo un-understandable..after watching ur videos this makes sense...!!Cant thank u enough!!!!!
What you said about the 2nd function of immunoglobulins at around 09:05 : Could there be a mistake in your video? It sounds like you're describing the function of the T-Cell-Receptor, but afaik T-Cell-Receptors aren't really immunoglobulins. Anyway I'm thankful for your video and it helps a lot!
Hi there Andrey! First of all thanks heaps for making this available to us students as they are really really helpful to recap things before examinations haha. But just a thing that I want to suggest. Would you mind standing on the left side when you're discussing the right half side of the board? Because this would make it easier to pause the video and read the material written on there before moving on. Much appreciated! Thank you so much! :D
can u plz help me ...how memory cells have memory?..are the b-cell receptors main reason for the memory bcz now ,still after diffrentiation these receptors on memory cell r specific for that same antigen..so in secondry response they can bind to that sepcific antigen again...am i correct?
+Meghana Bhushan Immunoglobulin is another name of antibody. Here, 'Immuno' means they are the molecules produced by our immune system; and 'globulin' means globular (spherical/globe like). antibody is made of four different types of globe like proteins , two proteins make light chain, other two make heavy chain. Overall antibody is Y shaped structure. Immunoglobulin is general term, antibody is more specific.
I love your channel. You help me a lot. Can you please find a way to pronounce my name in any of your videos like you do with your favourite rapper, 2-chains as in 2:22 :P.
I am asking this inspite of u writing "antibodies, also called immunoglobulins" because I've seen many sources that say both are slightly different. so plz do clarify this to me!.... :)
+Meghana Bhushan Yes! Good job for asking that question because technically they are not the same exact thing! You can think of an immunoglobulin as a more general concept than an antibody. Our body produces five types of immunoglobulins. Some of these can be bound to cell membranes while others are free floating. An antibody is an immunoglobulin that has been generated by a cell such as a plasma cell in response to being exposed to an antigen.
If anyone needs a mnemonic here's mine:
IgG - (General) - Makes up 75% of antibodies, generally distributed throughout blood. Long term immune response.
IgA - (Airways) - antibodies found in mucous, nasal cavities, saliva, lungs etc
IgM - (Major) largest antibody and first to respond to antigens. Highly effective against viruses.
IgE - (Echoo!) - Allergic reactions
IgD - (Differentiate) - Helps B cells get activated to differentiate them into plasma and memory B cells
IgG - passinG through placenta
IgA- teAr, sAliva, mucosAl
IgM- 1st iMMune responder.
connect with J- junction (j)i am = IgA & IgM
What a wonderful mnemonic, Thanks!!! A huge thanks to ak lectures as well for delivering these fantastic lectures!!
@@xpbatmanqx5535 No problem! Glad it helped
Great!!! I love it
You're welcome! Good luck with the exam, you got this!
I cannot count the times you've saved my life with your videos. As soon as I start a new course, the first thing i check is if you have videos up on my particular subject, you never fail to deliver. Love your videos, please never stop!!
AK Lectures; Helping grad students graduate since 2014
same here
So sad how people ignore these amount of knowledge on the internet, you sir deserve more views! +1
Don't judge others if you don't want to be judged....
This is useless information for the layman
6:21 for clear picture. Thanks sir for the really good explanation!
Please give this hero a Nobel prize! Thanx sir... thank you for everything :')
You got me through my exam of immunology, thank you so much! :)
Studying for the MCAT... you are literally saving my life... Thank you for all the hard work you do!!!
Best biochem teacher💯
I AM ALWAYS AMAZED HOW YOU ARTICULATE YOUR EXPLANATION. YOU ARE WONDERFUL IN DELIVERING SCIENTIFIC CONCEPTS. I AM THE HAPPIEST TO FIND YOUR EXPLANATION ON THE YOU TUBE VIDEO. YOU STILL TAKING THE LEAD.
Finally found a truly useful youtube channel, thank you so much your videos are the best
Your page is officially the best on youtube. I wish I had found this page like three months ago tho
Hi, nice video.
As far as i know, CTLs don't have antibodies that recognize MHC (as was drawn on the board), but rather TCRs.
I was just about to comment that
TCRs recognize MHC complexes, that's the point of them. So Cytotoxic t-cells have TCRs which recognize MHC-I or MHC -II
Best dude in history of youtube. Thank you sir for sharing your amazing knowlede
I just have to say that you're amazing,and the knowledge you give is also amazing!!
Does an antibody belong on the Cytotoxic-T-Cell there, on the diagram? Isn't that receptor is a generic T-Cell Receptor binding to MHC-I. Thank you for the effort that goes into your presentations, they are world-class.
You seriously deserves more subscribers......you r great.....hats off man.....
I love you you save my life like every other day, thanks for your videos
Your videos are very helpful and the way you make them makes everything seem so much easier!!!👏🏻
7 years and still informative
Just wanted to say thank you for all of your help. Your explanations make so much more sense than a book. Also what the heck is your IQ? You look very young for being able to lecture on so many topics. But I am so glad you do!!!!! THANK YOU!!!
very informative
thanks a lot, bro
the monoclonal AB video helped a lot as well, keep doing an amazing job
Fantabulous sir. My inspiration❤
Great videos. I'm amazed you get all this information over in a single take with no mistakes👍
AK you're the best i've ever seen thus far, keep it up
who else is watching this from 2021 BLESS THIS GUY
Great revision video just before my test! :)
what an explanation ?? you are more than amazing and brilliant
Thank you sir. Your explanation is really clean and simple making it easier for me to understand.
thank u for these wonderful videos . ur immunology classes are really helping for my studies
u r very awesome sir....I'm lucky to having u youtube teacher.........i wish to be a professor like u....thank u so much for ur awesome work for students....
u r too intelligent sir thankew so much .......... i can und very well only by urs video
+Simran Kotwal thats awesome! thanks:)
The best teacher ever
You are an excellent teacher! Thank you!
You did a great job. I suscribed as soon as I saw this video
I love this guy
Great explanation ❤
Could you make a video about how immunoglobulins are diverse? Meaning gene recombination with V(D)J segments, P and N nucleotides, and class switching? I think this is a hard antibody concept to grasp and you do an awesome job at teaching!
Thank you so much sir🥺
U just saved a student who found very hard understanding from textbooks
Thank you so much🙏🏻🎀🥺
Thanks a lot,it really helps me
Thanks sir .....you the best!!!!!!!!
could u please do the differences between proteins and enzymes?im never clear on this.thank you in advance
THANK YOU SO MUCH!!!!!
please don't stop making videos
Thank you sir.
This is do valuable for me to get ready for the exam soon.
Hopefully I will pass it
Thank you so much Sir for your amazing work.May Allah bless you with alot of happiness in mortal and eternal lives.
Very Helpful. Thank you for your time
yua lectures have been of great help to me. thankyu so so much.
many thanks. Thank you.
Informations that save lives.
Thank you! Your videos are so helpful!
SIR IT HELPED ME ALOT THANKS FOR MAKING THINGS EASY
U deserve more subscribers 👏
tq AK, your video is usefull how to teach my students. awessome
Thank you!
Thank you so much sir, for explanation 🤗🙏
Keep doing ur good work, love n respect all d way frm India 😁❤️
Thank u, all ur videos are always helpful!
Nice lecture sir 🙌🙌🙌🙌🙌
thank you sir for your effort and your greatful.
Well done, thank you for the videos!
many many thanks
8:30 Cytotoxic T cells should have T cell receptors, not antibodies.
It's true that naive Tc can be activated by antigen-presenting cells that are infected (e.g. Dendritic cells), but this has nothing to do with antibodies.
However, B cells have antibodies as receptors, a.k.a. BCR.
Education Revolution!
Thanks for your wonderful videos..u are rrally saving me..struggeling with i guess the worst biochem book (is basis for exam) written ever which makes simple things sooo un-understandable..after watching ur videos this makes sense...!!Cant thank u enough!!!!!
Thank you so much 🙏🙏🙏
Thanks! and could u make some tutorials about different types of anemias?
What you said about the 2nd function of immunoglobulins at around 09:05 :
Could there be a mistake in your video? It sounds like you're describing the function of the T-Cell-Receptor, but afaik T-Cell-Receptors aren't really immunoglobulins.
Anyway I'm thankful for your video and it helps a lot!
Hi there Andrey! First of all thanks heaps for making this available to us students as they are really really helpful to recap things before examinations haha. But just a thing that I want to suggest. Would you mind standing on the left side when you're discussing the right half side of the board? Because this would make it easier to pause the video and read the material written on there before moving on. Much appreciated! Thank you so much! :D
Marcus Leung Thanks! Sure, Ill try to remember that next time :)
Thank you 🙏🙏🙏
so nice and energetic,,,thanks a lot,,,
Thank You !!!
you are amazing
Loves from India
Again. You are the best ever. Born for this =D
Thank you so much, sir!!
Just a question: Shouldn't it be a cytotoxic CD8 T lymphocyte binding to the CMH1-antigen complex on a infected cell?
thnkewww so much sir.....i preprd..best fr my..seminar.
really perfect
Hmmm really informative. Think I may have explained something wrong once. Oh well. I know now.
thanks alot
the best ! thank you
2:35
The logo of ACM has some sort of resemblance with the morfology of antibodies
thank you so much
Great video , but I thought there will be a detailed explanation about the 5 classes of Immunoglobulins :(
thank you
Can u explain the const & variable region in brief ?
Can I have playlist of this video
can u plz help me ...how memory cells have memory?..are the b-cell receptors main reason for the memory bcz now ,still after diffrentiation these receptors on memory cell r specific for that same antigen..so in secondry response they can bind to that sepcific antigen again...am i correct?
How is it possible to have Antibody expressed on cytotoxic T cell?
Amazing
Why is there not a single video on RUclips about EXPERIMENT DEMONSTRATION OF ANTIBODIES??😭
You are awesome thanks
keep up the good work :)
More attractive education
I couldn't open this website please provide me this solution
Please provide clear notes i need screen shot
lifesaver thanksssss
Thanks for the video~!^^
ChicklePickle14 you're welcome! love the pikachu :)
Nice
sir could u plz tell me whether immunoglobulin n antibody are synonyms? if not what's the difference?
+Meghana Bhushan
Immunoglobulin is another name of antibody. Here, 'Immuno' means they are the molecules produced by our immune system; and 'globulin' means globular (spherical/globe like). antibody is made of four different types of globe like proteins , two proteins make light chain, other two make heavy chain. Overall antibody is Y shaped structure. Immunoglobulin is general term, antibody is more specific.
I love your channel. You help me a lot. Can you please find a way to pronounce my name in any of your videos like you do with your favourite rapper, 2-chains as in 2:22 :P.
dude dafuq r u saying...ak is a real teacher...he aint no rapper...
engsub please! my english skill is not good, i cant hear everything, please please!!!!
I am asking this inspite of u writing "antibodies, also called immunoglobulins" because I've seen many sources that say both are slightly different. so plz do clarify this to me!.... :)
+Meghana Bhushan Yes! Good job for asking that question because technically they are not the same exact thing! You can think of an immunoglobulin as a more general concept than an antibody. Our body produces five types of immunoglobulins. Some of these can be bound to cell membranes while others are free floating. An antibody is an immunoglobulin that has been generated by a cell such as a plasma cell in response to being exposed to an antigen.
Thanks a lot especially for a quick answer.. :)
+AK LECTURES (Andrey K) So it's like all antibodies are immunoglobulin but not all immunoglobulins are antibodies??
precisely!
0:50 "...for which it was built for...". His doctoring is better than his English. "..for which it was built. ..."
Now he is competing with eminem 🤔😂♥️