Nerve Physiology : Structure and Types of Neurons, Blood brain barrier, Resting membrane potential
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- Опубликовано: 27 ноя 2024
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Nerve Physiology : Structure and Types of Neurons, Blood brain barrier, Resting membrane potential
Structure and Types of Neurons
Structure of a Neuron
_____________________
Cell Body (Soma): Contains the nucleus and essential organelles.
Dendrites: Branch-like extensions that receive signals from other neurons.
Axon: Long projection that transmits signals to other neurons or muscles.
Myelin Sheath: Fatty insulation that increases signal transmission speed.
Types of Neurons
__________________
Sensory Neurons: Transmit sensory information from receptors to the CNS.
Motor Neurons: Transmit motor information from the CNS to effectors (muscles, glands).
Interneurons: Located within the CNS and connect sensory and motor neurons.
Blood-Brain Barrier (BBB)
_________________________
Structure and Composition: Made of tight junctions between endothelial cells of cerebral capillaries.
· Astrocyte foot processes reinforce the barrier.
Function
· Protects the brain from harmful substances in the blood.
· Regulates transport of nutrients and waste products.
· Blocks many drugs, bacteria, and large molecules.
Clinical Relevance: Alterations or breakdown of the BBB can lead to neurological disorders.
Resting Membrane Potential (RMP)
___________________________________
Definition: The electric potential across the cell membrane at rest, typically -70mV in neurons.
Mechanism
· Sodium-Potassium Pump (Na+/K+ Pump):
Pumps 3 Na+ out and 2 K+ in, creating a concentration gradient.
Requires ATP for energy.
· Potassium Leak Channels:
Allow K+ to flow out of the cell, following the concentration gradient.
Contributes to the negative inside relative to outside.
· Sodium Leak Channels:
Less permeable to Na+ than to K+, but some Na+ does leak into the cell.
· Balance of Forces:
The concentration gradient pulls K+ out and Na+ in.
The electrical gradient opposes this movement.
At rest, these forces are in equilibrium.
Clinical Relevance: Understanding RMP is crucial for understanding nerve impulse propagation, muscle contractions, and various neurological disorders.
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Most welcome
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Glad it was helpful!
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We will
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yes
Hi sir
25:00
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Sir can I get this note please
Why impulse is travelling from axon terminal to cell body from receptor, shouldn't the cell body take the impulse and travel through axon to axon terminal
It's bipolar neuron I think
Video will start from 24.12 min
Thanks bro
25:30
I can't tell in word's what a great work this channel is doing.. now i can really believe that education is for all, not only for wealthy...
I can't tell in word's what a great work this channel is doing.. now i can really believe that education is for all, not only for wealthy...
Hey man. have you already started studying 3 months back