2020 FH Global Summit Session 4: Lp(a) and Drivers of Inherited Risk

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  • Опубликовано: 21 фев 2021
  • Lipoprotein (a), Lp(a), is an important independent risk factor for premature atherosclerotic cardiovascular disease (ASCVD), including heart attacks, stroke and calcific aortic valve stenosis. Guidelines on whom to screen for Lp(a) are evolving and new therapies are emerging. In the 4th session of the FH Global Summit, Dr. Sotiorios (Sam) Tsimikas will highlight “Emerging treatments to reduce Lp(a)-mediated CVD risk” and cover:
    Session topics:
    - The wide heterogeneity of current lipid-lowering drugs on Lp(a) and their clinical significance
    - The debate: What is the required degree of Lp(a) lowering to meaningfully reduce CHD outcomes?
    Dr. Tsimikas will be joined by an individual with high Lp(a), Cyd Isleib, as well as Dr. Mary McGowan, the FH Foundation’s Chief Medical Officer, for a roundtable discussion on the real world implications of diagnosis and care of Lp(a).
    Learn more by visiting:
    thefhfoundation.org/2020-fh-g...

Комментарии • 26

  • @cmpremlap
    @cmpremlap 2 года назад

    Thank you for sharing!

  • @evelynmonsivais9430
    @evelynmonsivais9430 2 года назад

    Glad to be here...

  • @lucilacareaga9152
    @lucilacareaga9152 3 года назад

    Thank you very much for the valuable information

  • @joysegars9399
    @joysegars9399 2 года назад +3

    Has anyone determined that lowering Lp(a) decreases negative events? I know it did not when lowered with niacin. I’m hoping it does!

  • @evelynmonsivais9430
    @evelynmonsivais9430 2 года назад

    Wow. Look at Florida

  • @debstayblessed9549
    @debstayblessed9549 2 года назад

    I wish the experts, researchers would share about solutions
    For example, niacin therapeutically utilized is very beneficial 😉

  • @anilkumardhar
    @anilkumardhar 2 года назад +1

    hey, I am 58 year old and my lpa is 127 mg % and I want to be a part of phase 3 clinical trial of ASO. wish to know whether there is any centre in India??

  • @monaantony9096
    @monaantony9096 2 года назад

    Thank you for this information much gratitude Ihave been leading a disciplined lifestyle with plant based food and an hour of exercise But I’m saddened beyond words at the blood work result my general cholesterol leaves are all good but my Lpa is at 800 I’m so confused and depressed about this I do have a family history of heart issues but no early deaths in general My Dad is 80 no heart issues my mum was severe diabetic so that led to heart issues All my other markers calcium stress and inflammation level is all good So I need advice 🙏🙏🙏🙏

    • @marlymar7825
      @marlymar7825 2 года назад

      I was just given the news of Lpa and I’m around 139 nmol, I have very healthy eating and exercise habits. I’m fit and lean..My cholesterol is in in good standing with and HDL of 72, so I was pretty surprised to see these latest results.. I started doing a lot of research and I would suggest watching the video I watched right before this one. It is amazing educational information
      Hope it helps 🙏🏼🙏🏼💜💜
      ruclips.net/video/Slq_wWdul4g/видео.html

    • @debstayblessed9549
      @debstayblessed9549 2 года назад

      Niacin helps me. 1000mg. IR

    • @inthevortex-de1rh
      @inthevortex-de1rh 7 месяцев назад

      Watch dr Nadir Ali about this topic. He is a cardiologist with 30 years of experience and very smart!❤

  • @yeti9127
    @yeti9127 3 года назад +1

    Great presentation. My lp(a) is 10, and LDL is 166. My HDL is 56, and TG is 63. So my total cholesterol TC is 220+.
    My doctor wants me to be on Statin because he thinks my cholesterol -LDL and TC is unacceptable. I have some family history of heart issues.
    Am I at a high risk and need for Statin?

    • @JD-rc6lq
      @JD-rc6lq 3 года назад +1

      Watch Ken Sikaris presentation on this same issue
      ruclips.net/video/2p-mkbNutvQ/видео.html
      I believe he would say because your trigs are below 1 (euro) that you are not at risk for small dense ldl or lpa

    • @mohamedtawfeeq8524
      @mohamedtawfeeq8524 Год назад

      what's your apoB?

  • @edwardbanegas2153
    @edwardbanegas2153 Год назад

    So even with aphorisms and low lpa numbers, that womanstill has to have bypass surgery
    So lowering the lpa didn't change anything??

  • @katherineknight7630
    @katherineknight7630 3 года назад

    My LPa is 373 Nmol and went on Statins and it raised my LPa to 535 nmols. I went off statins and it bounced back to around the norm, 388 nmol. My overall Cholesterol has always been between 250 to 290, since I was 22 years old. I am 58 now. LDL average around 60, HDL average around 80 is, trigylcerides from 50's to 80's. I am in a trial now an MRNA trial, AMGEN-Olpasiran. So I am very excited to see what happens. phase one lowered the LPa by 90%, I am part of Phase 2. I have had no side effects at all. I am hopeful for the future. I should mention, althought no symptons, I pushed for testing and now have 6 stents, I do have significant blockages that were stented. Another interesting fact is I have no early onset heart disease in my family. My sisters LPa is higher than mine and she has a very low CT Calcium score. All 3 of my children also have high LPa.

    • @MN-go4gz
      @MN-go4gz 2 года назад

      Thank you for sharing please keep us posted!!

    • @susancanney-mcmahon9812
      @susancanney-mcmahon9812 2 года назад

      Hi Katherine, I just read this post today (4/2/22) and I want to say that my Lp(a) is also in the same range as yours. My children also have FH from their father and elevated Lp(a) from me, so they got a double dose of bad genes. I was wondering if you would share what tests you mean when you say you pushed for testing and ended up with 6 stents? I am seeing the lipid specialist in 2 weeks and want to go armed with the proper questions about testing. Thank you, Sue

    • @Sprint4serbia
      @Sprint4serbia Год назад

      @@susancanney-mcmahon9812 how are things?

    • @plants_and_wellness1574
      @plants_and_wellness1574 Год назад

      Any update to how you are doing today? My Lp(a) is 380 nmol/L, found out from a blood test and I’m getting a CT angiogram after meeting a girl on here that said she was diagnosed with CAD at 32 and she has high LPa. How did you find out that you needed stents?

    • @sheddkkhan6758
      @sheddkkhan6758 2 месяца назад

      @@plants_and_wellness1574helo

  • @plants_and_wellness1574
    @plants_and_wellness1574 Год назад

    Why are they reading a script 😕

  • @evelynmonsivais9430
    @evelynmonsivais9430 2 года назад

    The risk is the people who are in office and have been. The risk is the cults that are "family knit" ..clans. that's the risk.

  • @evelynmonsivais9430
    @evelynmonsivais9430 2 года назад

    Would you look at there JEBBIE