What is creatine and how does it work?
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- Опубликовано: 12 мар 2020
- This video presents an overview of creatine along with a detailed explanation of the molecular mechanisms involved with it. It also demonstrates how creatine supplementation impacts the molecular mechanism to provide benefits such as increased strength, increased muscle mass, improved performance and fatigue resistance.
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This video is provided for general and educational information only. Please consult your health care provider for Information about your health.
Royalty-Free Music from Bensound
This video was made by McMaster students Victor Nguyen, Ghazaleh Jafarazadeh-Maleki, Vaithiegaa Mathanarajan and Karan Taghizadeh in collaboration with the McMaster Demystifying Medicine Program.
Copyright McMaster University 2020
References:
Cooper, R., Naclerio, F., Allgrove, J., & Jimenez, A. (2012). Creatine supplementation with specific view to exercise/sports performance: an update. Journal of the International Society of Sports Nutrition, 9(1). doi.org/10.1186/1550-2783-9-33
Guimarães-Ferreira, L. (2014). Role of the phosphocreatine system on energetic homeostasis in skeletal and cardiac muscles. Einstein (São Paulo), 12(1), 126-131. doi.org/10.1590/s1679-4508201...
de Souza e Silva, A., Pertille, A., Reis Barbosa, C., Aparecida de Oliveira Silva, J., de Jesus, D., & Ribeiro, A. et al. (2019). Effects of Creatine Supplementation on Renal Function: A Systematic Review and Meta-Analysis. Journal Of Renal Nutrition, 29(6), 480-489. doi.org/10.1053/j.jrn.2019.05...
If you’re reading this, I cannot stress this enough: DRINK ENOUGH WATER WHILE TAKING IT. Also, it can cause stomach issues. I once shit my pants at a Halloween party because of creatine. Was not fun.
lmao
Man just shit his pants and blamed it on creatine 💀💀
@@emil335 maybe it was that gosh darned protein powder
lmao
Anyone else ever have a dream where they're pooping then they wake up and instantly think they sh!t themselves in bed?
@@DogsCoffeeNJesus nah blud that's just you 💀
Thanks for this man, simple and easy to understand, music is a little annoying but overall great video!
Shoulda put polo g
@@applebirds1nthefuture646 Shoulda put polo g
@@toddsheppard5411 Shoulda put polo g
The music is fine and it's not super loud. What lol
@@LarmadSomSecuritas Shoulda put polo g
I gave the vid a like mainly because this dood put in effort to explain, write, draw, erase, rewrite, redraw, and re-erase throughout the video. this is someone who put in effort. i understood about 10% of it. thanks for the information lol
Spectacular vid, im researching for my term paper on creatine uptake and usage in cells and this will be a huge help
Finally this is the video I wanted to see
I dont know if you will ever see this, but just the MONO audio channel detail made me like and sub! Well played.
Great video, also thanks for putting in the references
Wow, this was so clear! Thanks!
Fantastic explanation of the chemistry involved 👍many thanks!
Agree with everything except the last part. Creatine is the only extensively studied supplement to definitively increase muscle mass, and is widely considered safe.
He didn’t say it wasn’t safe 😂
It is important to respect the side effects. Coffee can make you twitch just like creatine can make you cramp, and people still use both
@@RioCuperuscaffeine is way worse for you than creatine monohydrate
Haha I found it funny when he wrote "Yay x2!" Next to the drawing having a smiley face🤣 Great video man. You Break it down well👍
Thanks for the information
Ive been using Creatine Monohydrate for a few months now, not once has it given me cramps, gas, or a feeling of dehydration, although every experience varies to some degree I’m sure.
One of the things that had concerned me was reports of hairloss/thinning, but I feel like there was sufficient enough research that had debunked that claim.
how has your water intake per day differed and how much do you drink now?
@@mootness_ There wasn’t a significant increase in water intake, I typically drink about 3 litres a day.
@@MrWookLoaf Have you experienced more sweating after intake?
@@BabyCEQ No I haven’t.
@@MrWookLoaf ok thanks for your reply
Thanks for the video!
Thank you☺️☺️
THANK YOU!!!!
Nice video
thanks, nice video
Amazing video, appreciate the info!
skhulootle muscles?
Thanks!
Any tips on how and when I should be taking creatine? Just ordered now
Great video, this helps!
Glad you think so!
Wel..iam going to tri it see resutls
3:57 Ooooh. Okay. Perfect graph.
When you take creative make sure to hydrate a lot and most this will not happen
Thanks for this video!
Do u recomend it for women?
I liked your video but the music was a little annoying, Thanks for the explanation tho ! Very well
I have kidney problems and the doctor said that I have my creatine too high. So thank you for explaining what that is
It's possible your are confusing creatine with creatinine. If you don't take creatine supplements and if you have kidney problems, your doctor was likely referring to elevated creatinine, which is a substance that your body produces which is normally eliminated at the same rate by the kidney. Doctors look at the creatinine in your blood to see if your kidney is working properly (in which case the creatine levels would be in a normal range) or not, in which case your kidneys would filter/eliminate less of the creatinine and thus leave higher concentrations in the blood. I'm not sure what your exact situation is but don't hesitate asking your doctor next time!
please speak up…turn the music off if you gonna be that low.
Great vid but please, you’re butchering how skeletal muscle is pronounced.
Mitochondria is the powerhouse of the cell
Why are you saying skeletal that way
Had to scroll down this far to ensure I wasn't the only one cringing at 'skeh-leetle'
Make audio louder plz. O have my volume maxed and still have a bit trouble hearing it
Love the vid but I believe it’s pronounced skell-et-all like skeleton, because it on our bones
You are wrong it is pronounced how he said it in the video
Very informative, but the music is very distracting making it hard to hear the voice over
Was it really necessary to put cat video music on this video?
How long should I take creatine monohydrate every single day before taking a break?
Should be taken daily - no break needed.
@@juliusholstein2376 so you are saying after taking it ever single day for 6 months straight, I should continue without stopping?
@@earlcoles5215 yes. no problems. Look up some research and see for yourself :) best of luck on da gains-
Trying to convince my parents to let me use creatine.
Lol same they think creatine is the same as roids
@@riccosu3599 i just bought it and its on its way without telling thewm imma just telkl them it gives me protein or something like that lol
same
Same😭😭😭
If you are young enough to need your parents permission, you don't need creatine.
If you are a teenager, your body is already in a an anabolic state due to increased hormone production. You need just 3 things to build strength and muscle.
1) A good consistent training routine.
2) Good nutrition. Enough calories to grow and enough protein. I will also include enough water. Even slight dehydration has a negative effect on training. Muscles is mostly water.
3) Recovery, meaning enough time away from training and enough good quality sleep.
Easy enough to research training and nutrition. Supplements really have nothing to offer until you are seriously following 1, 2, 3. You are better off having a really solid baseline, before supplementing. The only supplement at your stage is a good protein. You can get it from food, but shakes following work outs do help. - Cheers
Why your sound is very low?
Creatine is awesome. I use kre alkalyan tho
I use tren
Where does the creatine monohydrate come from.
Animal protein
@@DoomFinger511 False. it's from chemical compounds Sarcosine and Cyanamide and it does not contain any animal by-products
Good video but you can barely hear the guy if you’re not in a completely quiet room.
I'm just wondering whether skel-e-tal muscle was read properly 🤔
It was not.
I'm just messing brother good work 👏
skeletal muscles, skeeleetle muscles
Wait...are you purposefully pronouncing skelatal muscles as Skilittle muscles or is that a gag?
Can creatine cause hair loss?
no
Its all about your genetics
I find the music very annoying and distracting. Otherwise good video.
Great video and explanation. The music was awful and distracted from the material
Skel Leetle muscles
Skelitel muscles
Hahaha yeah… idk what’s up with that
Disconnect when reading?
Is he trying to say skeletal?
"Skleetal muscles" duh!
I could of did without the annoying music, overall great video though
All benchers in your gym lifting massive weights are on creatine
Possibly, but it is not necessary to build strength. Most people supplement to speed up gains.
All else being the same, a person would not get significantly stronger just because they took creatine. I have train off and on for years. Supplements have benefits but are not entirely needed.
For most people you can avoid all the negative side effects by drinking lots of water. When I was using it daily I was drinking 1 gallon of water everyday at 150 lbs body weight and never had a cramp.
You've got sugar in that spoon .. I know it 😂
skuh-lee-tul muscles
hey, be nice
Alright this is an amazing video but who the fuck says skeletal like that
People with degrees in medicine and biology
One guy "almost died" 😄
Can barely hear you
bro that music is so annoying, good explanation, but god damn, couldnt finish at how bad that tune was
Definitely a loading phase for about 2 weeks is the way to go. When I was a teenager I didn’t understand what a loading phase was so I took 10g of creatine for months!!! I got huge. At 18 I benched 375. But the second I got off of it. I got small lol
Yea that’s why I don’t think I’m ever gonna start taking it
That’s not how it works
That's BS it's not steroids. Physically, creatine makes people retain more water and look slightly bigger. Loading is unnecessary. You can just take 5g a day for a month and achieve the same full saturation you would by loading for 2 weeks but without the side effects.
Yo dat walmart creatine gives me dem sharts
great video but the music you are using is the main theme for "cuckold simulator" which got a giggle out of me.
Jack Murphy simulator
@@smokeysoldier8590 funny enough jack murphy was added to cuck simulator
Adenosine tri phosphate to Adenosine diphosphate
Skeletal. SKEL. Et. Al. Like SKELETON
Too quite
Man you talk so slow, had to watch on 1.5x
why are you whispering??
thanks man, i was so close to taking it . thank god i still love my kidneys
Did you even pay attention? There’s no risk at all. It’s not bad for your kidneys it’s harmless
So I'm assuming you either have a preexisting kidney condition or have a problem listening.
Long term use will sadly damage your kidneys
could you please link some studies?
@@benjamingadelangsted-aggre8860 its on my personal experience brother
@@downshift7300 how do you know
@@downshift7300 Nah you took steroids and blame creatine :D Theres plenty of studies disproving the myth of creatine affecting kidneys
I disagree, unless one has an underlying issue with kidneys. Sensible supplementation will not be a problem for most people. Having said that, I also believe great gains can be had with zero creatine supplementation. I have used it and had periods of not using it. Gains DO come faster with some
supplements.
you say "Skeletal" really weirdly....why do you pronouce it like that? ?scolitle what is that
?"
Skilital muscle??!!!