The accident that changed the world - Allison Ramsey and Mary Staicu
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- Опубликовано: 9 фев 2020
- Learn how Alexander Fleming discovered penicillin, and how the antibiotic has changed medicine and the treatment of infections.
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In 1928, scientist Alexander Fleming returned to his lab and found something unexpected: a colony of mold growing on a Petri dish he’d forgotten to place in his incubator. And around this colony of mold was a zone completely and surprisingly clear of bacteria. What was this mysterious phenomenon? Allison Ramsey and Mary Staicu detail the discovery of penicillin and how it transformed medicine.
Lesson by Allison Ramsey and Mary Staicu, directed by WOW-HOW Studio.
Animator's website: wow-how.com/
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View full lesson: ed.ted.com/lessons/the-accide...
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"There are no accidents"
-Master Oogway
- Bob Ross
@@bruh-kj1yo
That happens to all of us😅
@Andy T Dear friend, you don't know the context in which Adam is speaking and surely you haven't watched a cool and funny movie
@@bruh-kj1yo this is no mistake either
@@adamm.6384 Yesterday is history, tomorrow is a mystery and today is a gift, that is why it is called the present......
Hard to imagine how many accidents shaped human history as it is today
We should ask that question to Hitler's parents.
Rushil Patel 😂😂😂weak
Like how a wrong turn by the driver lead to two world wars, and all the inventions that came with them
Without the accidental discovery of America, there would be no tomato in Italian food. Shocking, right?
You were an accident.
Bob Ross would call this a “happy little accident”
"... like a lot of you kids out there."
- Rob Boss
@@clarkepercivaljaeblood4886 Like ur mum.
Albert Einstein
Happy little accident
the story isnt right. its a rare mold because mostly found in the tropics. I bet you the answer is where he went on vacation
@@clarkepercivaljaeblood4886 lol i wonder how many kids these days are secrelty accidents. kinda sad when you think about it
Can we just take a moment to appreciate the quality of their animations?
No
I think we should.
We should not
yos we shd
Yes
Everyone misses the point, it wasn’t the “accidental” mould in the Petrie dish that was important. It was Fleming having the training and insight to recognise the importance of his observations.
It was actually Florey that did that.
@@xiphocostal whoops, sorry, brain malfunction
Yeah like your birth.. though it hasn’t done much to change human history yet
The irony is, this isn't by accident. Americans downplay the discovery because they stole the patent from Fleming. They aren't interested in Fleming's humanity they simply wanted to make money
@@hotsauce0606😂😂
“That’s funny...”
-Alexander Fleming inspecting his neglected petri dish.
Next time herself complains I haven't done the washing up or cleaned the fridge.........
Alexander Fleming had first discovered penicillin by accident in 1928, but at that time believed it had little application. When Florey and his team recognised the potential of the discovery for combating bacterial infection, they faced the problem of how to manufacture penicillin in sufficient quantities to be of use. Heatley, although the junior member of the team, possessed a natural gift for ingenuity and invention. It was he who suggested transferring the active ingredient of penicillin back into water by changing its acidity, thus purifying the penicillin.
Although Fleming received most of the credit for the discovery of penicillin, it was Florey who carried out the first clinical trials of penicillin in 1941 at the Radcliffe Infirmary in Oxford on the first patient, a police constable from Oxford. The patient started to recover, but subsequently died because Florey was unable, at that time, to make enough penicillin. It was Florey and Chain who actually made a useful and effective drug out of penicillin, after the task had been abandoned as too difficult.
From Wikipedia Florey Chain and Heatley
Florey wasn’t going to give up. Interestingly the mould that penicillin is still derived from today is the same one that was found on a rock melon at a farmer’s market and cultured by the Florey team.
Thank you Alexander Fleming
Would like to take this guy for a round of drinks.
Also big thanks to Australian Howard Florey and his team who brought penicillin to medical reality. Florey, Chain (who worked with Florey) and Fleming shared the Nobel Prize. Ironically, Fleming, upon seeing Florey’s work, dismissed it in silence.
@@vinsgraphics Thanks for pointing that out. Florey and chain get forgotten.
The quality of these animations is amazing
i thought they were boring
_"We don't make mistakes, we just have a happy little accident."_
*~ Bob Ross*
You are literally everywhere.
Ted-ed thank you for providing such high quality content for free. Lots of love from India.
**sees mold**
Fleming: *hm yes, medicine.*
Its not like that. He analysed the mold and concluded there must be some sort of microscopic anti-bacterial activity going on. Grooooovy... groovy penicillin.
"We don't make mistakes, just happy little accidents"
"... like a lot of you kids out there."
- Rob Boss
Happy little accidents that would both benefit and hinder our species's effort in coexisting with microbes.
Krispy Krep said my mom
Genocides are definitivly mistakes.
I was a mistake...And that sure wasn't a happy one for my parents
I love your videos and it makes my day so much better whenever you upload! Thanks!
Same
The animations are beautiful and so is the narrator's voice !
This video production was very thorough and understandable from illustrations to the content. As a pharmacist, I am glad that it included the information about allergies, penicillin resistant organisms, and over prescribing of antibiotics.
As a parent I have a special gratitude to that pink liquid, Amoxicillin. I can't imagine having been a parent before this was available. Your child has a wicked earache or other infection, and the pink liquid makes it just go away. I know it's science, but it works like magic.
haha im allergic
Wise man once said :
_change the world_
_my final message. Goodb ye_
Firdos Emkay discoed?
Don't get it
@@assemameen332 Its the mars rover
*Insert old vg music here*
@@assemameen332 it's a new meme
Through TED-Ed, I can learn something new even at least in just a few minutes. This is what I think why it celebrates learning and education. Thank you for coming into my life, TED.
TED-Ed videos are the best! They have helped me with so many school projects, so, thank you.
Flemming forgets to keep petri mold in incubator : changes the world
Me forget to switch off the iron box : house burns
this is nostalgia for me because we went in-depth on penicillin in microbiology & I loved it
There is a chance that the mold on my 14 year old sandvich can cure everything!
why are you in possession of a 14y/o sandwich
It will probably cure constipation...
@@loki2240 thats what super spicy mexican food is for
@@pyroromancer The fact that it could still look vaguely sandwich-like after 14 years is a scientific marvel in itself.
Or grow a sentient mold
State of the art animations with clear and accurate narration! Great job TED-ED👍
I really love the animation of this video.
Another accident that changed my life
I met with Ted Ed
_in this laboratory, we love healthy accidents!!!_
Big brain time
Another reason for the rise in antibiotic resistant bacteria is due to some not finishing what has been prescribed. By not finishing the prescription entirely, not all of the bacteria are done away with, so those surviving bacteria build up a resistance to whatever almost wiped them out. When receiving antibiotics it’s very important to take the prescription the whole way through even if you don’t have anymore signs or symptoms.
The illustrations are on fleek! Thanks so much!!
Thank you to those supporting these videos, you are making the world a better place
Thank you so much for uploading this video. It is helping me get through the pandemic!
*Basically why the term “accident” isn’t always a negative setback...*
Thanks ted ed for making this video cuz my cousin thought she had Penicillin allergy but she didnt I told her about this today morning and she met our family doctor and he told her she doesn't and now she knows thanks again and keep up the good work
beautiful animation. Kudos for the animation team
Also the animation in their videos is just 👌🏻👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻👏🏻
Do you know how they make these animated videos? Or which tool do they use ?
@@MrBluemaw did i ask?
I LOVE ALL OF TED- ED'S VIDEOS OMG
It’s crazy how many life changing situations we miss everyday just because we are not fully present, aware and educated
Bravo to your great efforts 👍.I don't have words to appreciate it 🤔😉
This one man has saved countless lives
Im interested in Peniciline because of Time-Travel and Reincarnation-Stories: so can someone tell me the Knowledge in the Format of 'Heres how YOU could make use of this knowledge if you were sudenly in the Bronze-Age!'
Very well made Video , Thank you !
I love your vids they give so much knowledge 😁
Absolutely amazing!
"It's essential that doctors not over-prescribe the drug."
Meanwhile, animal agriculture has over-used antibiotics leading to the resistance we're seeing.
Antibacterial soap, one of the worst creations in history, up there with glyphosate
@@3mtech It has nothing whatsoever to do with antibacterial soap.
@@ian1352 Such authority. With which chemical scheme are you associated? Don't mistake antibacterial soap and hand sanitizer.
@@ian1352 Bacterial resistance has a lot to do with antibacterial soap, which is no better at cleaning hands than proper soap and strengthens bacterial resistance by only killing the weaker bacteria.
Thank you for your efforrs
your videos make my day
I read the same thing in school but this video makes it soo fun and easy to understand.
Great video without too much additional fluff and straight to the information
HELP! Im interested in Peniciline because of Time-Travel and Reincarnation-Stories: so can someone tell me the Knowledge in the Format of 'Heres how YOU could make use of this knowledge if you were sudenly in the Bronze-Age!'
Thank you for sharing :)
what gorgeous animation :o
One of the few times I am part of the 1%
Penicillin and related β-lactam antibiotics give me a severe rash, eczema, and upset stomach. But I can also enjoy cheeses that contain P. Camemberti (Camemberts, brie, cambozola) and P. Roqueforti (roquefort, Gorgonzola, almost all blue cheeses) without issue.
And yes, this has been confirmed in adulthood for me.
Usually the doctor has to go for Cephalospirn C and some other antibiotic to make it work.
Awesome and informative video
When I gave my daughter amoxicillin, she threw up and broke out in hives, which went away not long after. She wasn't even sick, she was taking it prophylacticly after a tick bite while we waited for the test results. So I'm pretty sure she's allergic. But good to know that she may outgrow it.
why does it matter if she outgrows it? there are plenty of other antibiotics out there
I never outgrew mine 😩. But as someone else said, there are plenty of other antibiotics that aren’t penicillin based.
@@tlowry6338 Even if there are plenty of antibiotics out there, that doesn't mean you want to have closed doors to their use. If you're severely allergic to oranges, sure, you can eat other fruit, but that doesn't mean you don't want to be able to eat oranges like anyone else. And if you end up starving with only oranges as your potential source of food, you kind of wish it wasn't deeply unpleasant or life threatening to eat them.
Obviously, being allergic to penicillin isn't the same as being allergic to oranges, but the idea is that having your options be restricted is generally not something you want, and is typically something you do care about.
I’m allergic to penicillin to.
@@haleyhughes4591 take erythromycin then
superb animation...
You're voice is so calming
Thank you for probably saving my life Alexander Fleming, I was very sick while growing up
Great video👍🏻
I took it today! Helped me tons
Would love a video on bacteriophages / phage therapy! We are slowly headed towards fully antibiotic resistant bacterias, and phage therapy is a potential alternative.
Never understood this so well before
TED ED I LOVE YOUUUU
Had gone over this in my evening class last week and today Sulfa drugs. TED-Ed, go ahead and do your thing!
I love you ted-ed team.
What an amazing chance discovery.
I remember learning about this in 6th grade.
Me too
8 th class
I learned it in 7th grade?!?!
I learned it this year and im in 6th grade but then again i learn a lot more in science then others do because im homeschooled and always have been
Yeah me too now our kids are tought non sense and how to be identified with 1millon genders
I've worked on Alexander Flemings house in Edinburgh, still kept in good condition to this day
Very good ted ed
A famous quote this video shows getting mistakes is good so you can learn from them.
The final episode of Are You Afraid of the Dark is about a girl who dies from taking a penicillin shot. It has been about 20 years since I last saw it but it's the one episode I can never forget. Still frightens me till the day. I understand why some might be hesitant from taking it.
I Dont know what would I do without ted-ed
It's because of him I'm alive right now. I'm currently in the hospital recieving intravenous antibiotics to help me get over pneumonia and severe sepsis plus I have bacteria in my heart valve and they have me on extremely potent antibiotics to help kill the bacteria in my body. I've been getting the antibiotics for about a month and a half and I still have three weeks to go. But because of his mistake leaving out that petri dish, I'm slowly but surely recovering. Funny how I came across this video though just watching some other ted ed videos and then this one gets recommended to me so of course I had to click.
I hope for this to become my title one day...
"The accident that changed the world"
In a good way hopefully.
wonderful
Very informative! I haven't had penicillin in over 50 years after a bad reaction as a toddler ("turned red and blew up like a balloon" is how it was described) so it may be worth investigating if I'm allergic today.
Awesome.
Penicillin saved my father's life when he was 20 years old in 1943. As a consequence, he became so enthusiastic about antibiotics, he popped a pill if he ever sneezed more than once (for real). In his late 60's, he contracted an infection while in a hospital for a minor procedure, and no amount of sophisticated modern antibiotics were able to save his life. As a consequence, I steer clear of antibiotics (propolis included), unless it is a case of life and death.
Is he alive today?
@@lintoppthomasbruh can't you read
Fleming was not only a brilliant doctor and scientist, but an extremely moral and decent human being.
"I found penicillin and have given it free for the benefit of humanity. Why should it become a profit-making monopoly of manufacturers in another country?"
Keflex had saved me from several infections in my lifetime. One particular severe throat infection in particular. I caught that aggressive infection at Yosemite National Park, of all places.
Ah, so happy Ted ED is acknowledging my contribution to the world
I didn't understand what accident you were talking about? until I saw those first lines on the second scene of the video, and when I thought of penicillin, the Penicillium fungi, Scottish biologist Alexander Fleming, and the word " first antibiotic " immediately came to mind.
This is pretty good, even though now penicillin can be replaced by bacteriophages
Manik Tuteja not safe for pregnant women or nursing mothers
Well, penicillin has already been replaced by many other antibiotics, it has almost no use today.
So many great scotts
This is very intresting😀
Nice art direction.
History is a complicated matter as it is everything, every little messup, invention or iconic event.
Wow, I always say to doctors that I heard as a kid that I am allergic to this and they shrug their shoulders. Now, thanks to this channel I know why.
Ohhh wowww interestiiiiiiing !!hey is this penicillin that’s in an epi pen ??
It 's my first time to see channel but i have got more information about penicillin thank you TED God bless you. this is a very little gift Knwoledge that God given Us. we suppose to go deeper and to find the solution for other chronic diseases Because we have authorities from the heaven
Aw I thought this was going to be a movie about the cats remake
A psychopath goes into a store
, he approaches the man at the counter and says:
"Hey man, may I have an assault rifle, 3,000 rounds, a scope, and a box of penicillin?
"
"Sorry sir, I can't sell you penicillin without a prescription."
Lmao
“A shame, guess I’ll stick with rubbing lemons.”
TED Ed You rock
" *I LOVE TED ED* "
-Curious Brainz
This video is helping me with my work from school tank you so much
Working with Alexander Fleming in his lab was a lab assistant, later a well-known ob-gyn, Jack Suchet. His sons include John Suchet, the radio host, and David Suchet, the actor and creator of "Poirot" on TV among other varied roles onstage and off, and a great evangelist as well. Among Jack Suchet's "children" meaning that he was the ob-gyn attending, were Anthony Horowitz, who came up with the show title "Midsommer Murders" and created "Foyle's War".
Wow.... just wow
A shrine should be built honoring people like Alexander Fleming.
Yes
In English class I got Alexander Fleming and got a encyclopedia to research about him and yep what an accident a pretty good one
“The accident that changed the world.”
“You.”
Uh ok
OK boomer
Noober Nebula Bro why..
Master Oogway : “There are no accidents”
Master oopsway
Everyone talks about Flemming, who discovered Penicillin, but didn't do much with it. The clip mentions "researchers figured out how to isolate the active compound", they then developed it into a Medicine, how about mentioning their names. Howard Florey and Ernst Boris Chain.
nice content
Hard to imagine how many accidents that changed humanity till today?
Comment thief :v