Managing Acute Toxicities of CAR T-cell Therapy

In this episode, we discuss the management of acute toxicities of CAR T-cell therapy, including CRS, ICANS, and HLH with Dr. Michael Jain from Moffitt Cancer Center.
Here are some of the key articles we discussed:
1. “How I treat refractory CRS and ICANS after CAR T-cell therapy”.
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2. CAR-HEMATOTOX score:
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3. “How I treat cytopenias after CAR T-cell therapy”.
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4. Immune Effector Cell-Associated HLH-Like Syndrome (ASTCT):
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5. ASTCT consensus grading for CRS and ICANS:
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6. Hematopoietic stem cell boost for persistent neutropenia after CAR T-cell therapy:
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7. Modified EASIX score for predicting CRS and neurotoxicity:
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