How Opioids, Overdoses, and Breathing Are Connected | Christopher Wyatt, PhD | TEDxDayton

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  • Опубликовано: 21 янв 2021
  • What happens inside your brain when it comes to breathing? This is the question Christopher has spent years researching. By starting with the brain’s role in breathing, he uses this talk to give listeners a new insight into how opioids work. Opioids are powerful drugs that, when used properly under medical supervision, can work wonders for those suffering from constant, intractable pain. When used recreationally or outside of sound medical controls, the scourges of addiction and overdose are high. Christopher explains the how’s and why’s of both sides of opioids and the brain, in a talk that makes the science accessible to all. Christopher Wyatt is originally from Manchester, England. He has a PhD in Neuropharmacology and for the last thirty years has researched the neuronal control of breathing with particular interest in how disease states and medicines alter breathing. He has over fifty publications on the control of breathing and his laboratory has been funded by NIH, The American Heart Association, and the pharmaceutical industry. Chris lives in Yellow Springs, is married to Karen, and has two teenage sons: Bob and Morris. To relax during this pandemic, he walks his two crazy little Patterdale Terriers: Betty and Archie. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

Комментарии • 23

  • @merncat3384
    @merncat3384 2 года назад +2

    Excellent information !!!

  • @parrishwoods
    @parrishwoods Год назад +2

    You are the only person I have ever heard talk about the oxygen problem with opioids.This has been causing me so much pain and then they give me progabyline or lyrica which made me sleep all the time . And every time I got up from sleeping. I was in so much pain because I didn't breathe.Literally starving and no one else is talking about it. In this sweating business.I've been going to a pain center since two thousand eleven

  • @Paulsapartment
    @Paulsapartment 3 года назад +2

    Right on Chris!!! Love this Ted talk and next time I visit ys we have some catching up to do!!

  • @Killuminati2025
    @Killuminati2025 2 года назад +2

    Good hearted man

  • @husaynshaikh9826
    @husaynshaikh9826 2 года назад +2

    salute to that man

  • @belindagrigsby3535
    @belindagrigsby3535 Год назад +2

    This talk meant so much to me. Compassion, truth and integrity! Thank you.

  • @parrishwoods
    @parrishwoods Год назад +1

    So. So now I know what's wrong with me and I wanted to know more . So why is the video chopped off? Where is the answer? This left me needing more

  • @MrDoggy54
    @MrDoggy54 10 месяцев назад

    Knowledge through science and emotion finding right answer without pre conceive notions

  • @parrishwoods
    @parrishwoods Год назад +1

    I can't even take a nap. Because when I wake up. I hurt all over from no oxygen

  • @hayleydoherty9557
    @hayleydoherty9557 Год назад +2

    no high, still in pain and a whole host of problems im illequipped to deal with after 4 years on the stuff perscriptioned by dr

  • @ralphdavidson9542
    @ralphdavidson9542 Год назад +1

    much the same addiction process as alcohol.

  • @wg1948
    @wg1948 Год назад

    can one overdose on targin let's say 2- 20mg?

  • @davidhart9106
    @davidhart9106 9 месяцев назад

    The use of opioids reduces the number of opioid receptors?
    I thought it reduced the number of presynaptic vesicles, and increased the number of postsynaptic receptors.
    Will you please clarify?

    • @joshbodzin5093
      @joshbodzin5093 4 месяца назад +1

      The two major theories of opioid tolerance involve changes in opioid receptors. One theory purports that receptors undergo changes that result in decreased receptor activation, or desensitization, with prolonged exposure to opioids. This can cause an increase in pain and the need for a higher dose of medication. The other line of evidence suggests that a gradual decrease in the number of available opioid receptors is at least partially responsible for the development of tolerance.

    • @davidhart9106
      @davidhart9106 4 месяца назад

      @@joshbodzin5093 Interesting. I was under the impression of the former, was unaware of the latter.
      Thank you.

  • @jd5094
    @jd5094 Год назад +2

    Not everyone responds to opioids the way this guy describes. For many people, the high is not pleasurable and there is no lessening of pain. In fact, the mental and physical suffering is agony. This guys description of the opioud experience really is a fantasy.

  • @EDD519
    @EDD519 Год назад +2

    he forgot the Main subject ! PAIN , CHRONIC PAIN , FOREVER PAIN, no one will speak on it !!

    • @jakethomas740
      @jakethomas740 Год назад

      Hi I'm currently going through this can I please elaborate and lmk if u find a care PLEASE!! In so much chronic pain

    • @EDD519
      @EDD519 Год назад +1

      @@jakethomas740 try kratom, it works !

    • @jakethomas740
      @jakethomas740 Год назад

      @@EDD519 do u recommend I order and make a tea from it or buy capsule pills form

    • @EDD519
      @EDD519 Год назад

      @@jakethomas740 either way ,it will work !

  • @bil.johnson_
    @bil.johnson_ 2 года назад +1

    This even have 2000 years