Acylation (Acid Anhydride Reactions)

Another Acylation reaction! This video looks at the Nucleophilic Addition Elimination reaction mechanism of acid anhydride. It will also look into one the most used pharmaceutical drugs in the world. Take a look to find out.

[@star_boi2593]

watching this at 2x speed for my exam which is in less than 2 hours :))))))))))))

[@MrEekaz]

Just wanted to say thanks for your videos, they've really helped me get to Medical School by helping me get my A in Edexcel A Level Chem :)

[@AlleryChemistry]

Ah congratulations! Good on you for passing, I assume you are 1st year medical student?

[@MrEekaz]

Thank you, yes I am

[@jackw1014]

Thank you! My textbook doesn't show this mechanism, so you're a lifesaver!

[@nomchicky7515]

Perfect timing, I'm just covering this in class! Thank you!

[@AlleryChemistry]

You're very welcome.

[@ayesharana9802]

Smashed it again! Thanks Chris

[@kiesha2833]

This is so well explained, l really understand it now. Thank you

[@fadumoabdirahman5794]

some textbooks show the water nucleophile to have one lone pair and others show it to have two lone pairs on the oxygens im not sure which to use.

[@05forn]

i dont think the h just falls off. Im pretty sure u have to use some sort of base like pyridine or NET3 to take the hydrogen. So how would u protonate the product if there is no free h+ floating around?

[@Mo-ls8qe]

thank you so much for these videos, organic gets really confusing to me :)

[@MrSensible2]

Silly question but with a definite reason for asking....if you mix two (acidic) molecules of succinic anhydride with one (basic) molecule of Zinc Oxide, what happens? I know one mole of Zinc Oxide can neutralise two moles of alkyl thio-acid to make ZDDP. Can it perform a similar trick with SA?

[@letsprepare5437]

Love you... God bless u in your journey

[@eesaakhan6448]

Great video! is this video also relevant for the AQA syllabus?

[@AlleryChemistry]

Yes definitely. You can find all the other AQA vids via this playlist ruclips.net/channel/UCPtWS4fCi25YHw5SPGdPz0gplaylists?sort=dd&view=50&shelf_id=2 Hope this helps!

[@andreadirosa2966]

Why didn't you mention the acid-catalization of the reaction?

[@xiaoyihu7368]

Thank you so much !!!!!

[@ranishelar2214]

Superb

[@harshitaawana9431]

thank you so much!!!!! this video really helped me alot

[@AlleryChemistry]

Glad it helped!

[@khan99ish]

Hi sir should we be aware of acid anhydride reactions for OCR A as nothing on the specification says about this?

[@AlleryChemistry]

No, not for OCR A. Breathe a sigh of relief 😌

[@user-ne8tx2gr1p]

hello teacher l am amedical student in my first stage and l want to study medicine in Britain or America 🇺🇸 l have not any information about that could you help me please?

[@kurusb7792]

if anything the volume is very sensible, don't hv 2 strain your ears for every word he is speaking