Transport Proteins: Pumps, Channels, Carriers

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Video Summary:
Transport proteins create a passage for lipid insoluble and larger molecules to cross the biological membrane. They can be pumps, channels or carriers. Pumps use energy from ATP to drive the primary active transport of a substance against its electrochemical gradient. Channels provide continuous passage for passive diffusion down the electrochemical gradient. Diffusion through channels is faster as multiple ions can pass through the channel during each opening. Pores are always open and gated channels switch between open and closed states. Carriers do not provide continuous passage. Movement through them is relatively slow. Uniporters move a single type of substance down its concentration gradient. Symporter moves one substance downhill and uses it's energy to move other substance uphill in same direction. Antiporters also move one substance downhill and uses it's energy to move other substance uphill but in opposite direction.
🎞 More videos on membrane transport
• Primary vs Secondary Active Transport: • Primary Active Transpo...
• Transport Through The Cell Membrane: • 11. Transport Through ...
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Dr Vipul Navadiya
DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.

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[@NonstopNeuron]

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[@NonstopNeuron]

Glad to hear that. Please share the videos to support the channel. Thanks.

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[@vinodgupta1628]

Crystal clear explanation !!

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Really useful explanation, thank you!

[@cylestyy]

this video cleared all my doubts about transport proteins!!!

[@choureyharshi2268]

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[@nighttwist]

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Thank you

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[@NonstopNeuron]

Thank you 😊

[@akbarshoed]

Very well done

[@nurathirahabdullah3649]

Channel Protein- 1:45
Carrier Protein- 3:14

[@user-yz4oo5nv2c]

what an amazing explanation

[@vibhavattreja2428]

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[@NonstopNeuron]

You are welcome!

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[@tabtheysay]

Forgot about mechanically gated channel, but great video overall. Thanks.

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Thank you. Please share the video. We need your support to be able to keep making the videos.

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[@NonstopNeuron]

Currently I am focusing on physiology. Clinical subjects will take very long to come. But yes I want to cover as much as I can.

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[@Usman-ni7sc]

Actin: A cytoskeletal protein crucial for cellular structure and movement.
Myosin: Motor protein involved in cell motility and contractility.
Tubulin: Forms microtubules, aiding in intracellular transport and cell division.
Vinculin: Connects actin filaments to integrins, contributing to cell adhesion.
G-actin and F-actin: Monomeric and polymeric forms of actin, respectively.
Fibronectin: An extracellular matrix protein interacting with cell surface receptors.
Calmodulin: Involved in calcium-dependent signaling pathways.
Profilin: Regulates actin polymerization
and dynamics.
Talin: Binds to integrins, linking them to the actin cytoskeleton.
Cofilin: Modulates actin dynamics by promoting depolymerization.
Can anyone tell me if these are peripheral proteins even if it can be perpheral proteins and transmembrane both....ai provided this..I wanna check it's accuracy....btw nice video🎉🎉

[@itsme_annu]

Sir can you name the proteins which are help in translocation?

[@lecy1075]

thank u my exams tmrw and i was confused

[@shanthala1345]

How is symporter and antiporter different

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[@gadielpedrazamonroy2511]

Excuse me, I have a question, in which program did you make your animations?

[@NonstopNeuron]

I use multiple softwere. Affinity designer, blender, power point, inkscape etc

[@user-xn1xe6tt7j]

👍

[@asatident3555]

💫🙌

[@Yaaah68]

Water occurs the membrane in which type ?

[@NonstopNeuron]

Aquaporins

[@elpidakeremidou3702]

I have a question about chanells. Specifically Gated chanells. after the gate opens we see the transport of ions is like facilitated diffusion (does not require energy). But, dont we need energy for the gate to open? So in the end can we say it's facilitated diffusion?
Again very helpfull video, you gained a subscriber

[@NonstopNeuron]

No energy is not required for gates to open. But we can't say it's a facilitated diffusion. That is different.

[@elpidakeremidou3702]

@@NonstopNeuron oh okay, so what kind of transportation is this?
Thank you for your time

[@NonstopNeuron]

It's diffusion. But facilitated diffusion has some differences. In facilitated diffusion, the carrier interacts with the substance.

[@elpidakeremidou3702]

@@NonstopNeuron okay i see. Again thank you very much. Have a nice day 💙

[@NonstopNeuron]

Most welcome. Same to you

[@aadi2625]

Carrier protein is active or passive??
In some sites it is written active

[@NonstopNeuron]

Passive

[@aadi2625]

@@NonstopNeuron I don't think so. Even in csir net books it is written active

[@asatident3555]

💪🤙

[@ibrahimvlogs9223]

Is this is applicable on plants also???

[@NonstopNeuron]

No idea. Anyone from botany...!

[@bts_0722]

I have a doubt
That some of the teacher says that water molecules can enter the cell by passing through phospholipid layer so what's the thing with water channel
Is there are some cell which have water channel and in some water transported through phospholipid layer

[@NonstopNeuron]

Water transport through lipid bilayer, even if it happens, is negligible.

[@bts_0722]

@@NonstopNeuron so mainly the Water is transported by water channel in plant as well as animals ..
Isn't it??

[@anmolenagbanshi8421]

Membrane transport proteins me kiya kiya likhna padega heading me

[@NonstopNeuron]

For that read the notes on our website. They are designed for quick revision and to help during exams. Here is the link for this topic: www.nonstopneuron.com/post/cell-membrane-transport-proteins

[@mohitsahu5467]

But ncert classs 11 says different things. According to them carrier proteins do active transport and there is no mention of pump proteins ..... I am confused... Kindly clear my confusion

[@NonstopNeuron]

Carriers do secondary active transport. In this, energy from downhill movement of one substance is used to move another substance uphill. But pumps are different. They are powered by ATPs

[@user-sq3ls6sj7i]

I can't see any difference between pumps and carrier proteins
Could you help me

[@user-sq3ls6sj7i]

Like na k pump is just like carrier protein (never provide continuous passage)

[@NonstopNeuron]

Pumps transport against electrochemical gradient. Carrier transports down the gradient.

[@user-sq3ls6sj7i]

@@NonstopNeuron but carrier proteins are used in secondary active transport too..

[@shanthala1345]

What's the difference between secondary active transport and active transport 😔

[@NonstopNeuron]

This video may help: ruclips.net/video/N-iBdwtQn4Q/видео.html

[@shanthala1345]

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[@gamerboi8092]

Cell membranes are made up of phospholipids. Not only lipids

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[@NonstopNeuron]

I can understand...😂😂😂😂

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Thank you so much

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Thank you so much