Is drinking milk a Superpower? Genetic Mutations: Crash Course Biology #37

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  • Опубликовано: 3 июн 2024
  • Science fiction is full of superpowered mutants, but in reality, mutations are much more diverse and complex. Sometimes, they can change someone’s entire body, and other times, we don’t notice them at all! In this episode, we’ll unpack what mutations are, how they work (including substitutions and frameshift mutations), and how scientists are learning to control mutations using tools like CRISPR/Cas9 and gene therapy.
    Introduction: Mutations Outside the Movies 00:00
    What Are Mutations? 1:20
    What Determines Mutations' Effects? 3:10
    Types of Mutations 4:16
    Positive, Negative, or Neutral? 7:43
    Gene Therapy & CRISPR 8:23
    Pharmacogenomics 10:59
    Review & Credits 11:58
    This series was produced in collaboration with HHMI BioInteractive, committed to empowering educators and inspiring students with engaging, accessible, and quality classroom resources. Visit BioInteractive.org/CrashCourse for more information.
    Check out our Biology playlist here: • Biology
    Watch this series in Spanish on our Crash Course en Español channel here: • Crash Course Biología
    Sources: docs.google.com/document/d/1G...
    ***
    Crash Course is on Patreon! You can support us directly by signing up at / crashcourse
    Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
    Leah H., David Fanska, Andrew Woods, DL Singfield, Ken Davidian, Stephen Akuffo, Toni Miles, Steve Segreto, Kyle & Katherine Callahan, Laurel Stevens, Burt Humburg, Perry Joyce, Scott Harrison, Mark & Susan Billian, Alan Bridgeman, Breanna Bosso, Matt Curls, Jennifer Killen, Jon Allen, Sarah & Nathan Catchings, team dorsey, Bernardo Garza, Trevin Beattie, Eric Koslow, Indija-ka Siriwardena, Jason Rostoker, Siobhán, Ken Penttinen, Nathan Taylor, Barrett & Laura Nuzum, Les Aker, William McGraw, Vaso, ClareG, Rizwan Kassim, Constance Urist, Alex Hackman, Pineapples of Solidarity, Katie Dean, Stephen McCandless, Wai Jack Sin, Ian Dundore, Caleb Weeks
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Комментарии • 39

  • @samstromberg5593
    @samstromberg5593 2 месяца назад +33

    I haven’t been here in a while so I’ve only ever seen Hank Green (I think that’s his name?) do these but oh my gosh this guy is gold

  • @AlienBemular
    @AlienBemular 2 месяца назад +42

    There's a character named Bone from One punch man who gets Durability from drinking a lot of milk.

  • @johndillinger6563
    @johndillinger6563 2 месяца назад +26

    I'll take the well rested mutation if I have a choice. 😁

  • @mickmash13
    @mickmash13 2 месяца назад +20

    I have hypermobile EDS, which is a mutation in how my body produces connective tissue. But there are other types that can affect other systems in the body. There's even a lot of variation in how severe hEDS is. I'd be curious to see the genetic variations between various types of EDS and the severity of EDS symptoms.

  • @Velvetynailworld
    @Velvetynailworld 2 месяца назад +7

    My kids and I watch only these biology videos. You’re such an amazing teacher and one of the more engaging ones for sure.

  • @angiepen
    @angiepen 2 месяца назад +11

    Yet another example of how awesome Dr. Sammy is. Hopefully he's already set up to do a Crash Course Entomology some time in the near future. :)

  • @williambilyeu9801
    @williambilyeu9801 2 месяца назад +19

    Dr. Sammy calling for his super suit remind me a Freezone from "The Incredibles." 😊😅😂

  • @suvikhyasiingh6073
    @suvikhyasiingh6073 2 месяца назад +14

    we also have a gene named sonic hedgehog which is an essential part of embryonic development.

  • @phoenixaasted
    @phoenixaasted 2 месяца назад +11

    Dubious food from legend of Zelda 1:58

  • @Aki-yq9bw
    @Aki-yq9bw 2 месяца назад +6

    Great video as always! Thank you!

  • @asiaeve4066
    @asiaeve4066 2 месяца назад +5

    So interesting! Makes me miss biology lol I may take a college class in it senior year 😋🧬✨

  • @b1laxson
    @b1laxson 2 месяца назад +1

    It is important to know your family medical history like parent and grand parents. The "mutations" they had are more likely to be ones you have. Knowing what they had to avoid or benefit from is good for yourself. For example there are some at risk of addiction affects so should just never start.

  • @johnm3066
    @johnm3066 2 месяца назад +2

    Crazy how our bodies cells and genes resemble a computer program, i.e data structure or algorithm.

  • @abramisme
    @abramisme 2 месяца назад +3

    nice! thank you for all you do! keep it up!

  • @user-pk4hn1uz1k
    @user-pk4hn1uz1k 2 месяца назад

    thanks, please update the playlist

  • @dreamcatcher5502
    @dreamcatcher5502 2 месяца назад +1

    Amazing !! Can you make a video explaing the MTHFR gene mutation please ? I carry 2 coppies and it has caused me a lot of problems over my life. Thank you for all your work !! ❤

  • @kmcsciguy
    @kmcsciguy 2 месяца назад

    Excellent video covering mutations and the details!

  • @Caterfree10
    @Caterfree10 2 месяца назад +1

    The reason I remember the ACTG letters is bc of GCAT in Homestuck lol. Useless info for me given I’m not exactly a geneticist but hey, it’s a good memory device anyway.

  • @gailaltschwager7377
    @gailaltschwager7377 2 месяца назад

    Thank you!

  • @gamerkid2759
    @gamerkid2759 2 месяца назад +4

    Good video!

  • @Davlavi
    @Davlavi 2 месяца назад +1

    Very cool thanks.

  • @turtletom8383
    @turtletom8383 2 месяца назад

    Have y'all done one on horizontal gene transfer. If not please do.

  • @hassenfepher
    @hassenfepher 2 месяца назад +1

    Fyi. Eating ice cream from the carton while watching this. Super power!!!

  • @pedrostormrage
    @pedrostormrage 2 месяца назад

    6:22 "There's a chance that these 'silent mutations' aren't so silent at all" Yeah, a few important factors here are codon optimality (changing a codon can slow down protein production even if codes for the same aminoacid), mRNA structure (changes in the mRNA sequence affect its folding pattern, which in turn affects interaction with other proteins or how efficiently it's translated), and splicing (they can create or destroy splice sites, changing the final mRNA).

  • @mymechanicfriend6017
    @mymechanicfriend6017 2 месяца назад

    Great Work ✊🏾☝🏾🔥📖📠

  • @MarcLeitermann
    @MarcLeitermann 2 месяца назад

    Fantastic presenter!

  • @johnadams3802
    @johnadams3802 2 месяца назад

    "Where is my supersuit?"
    I've been asking that question since I was a kid.

  • @Caterfree10
    @Caterfree10 2 месяца назад +1

    STATIC SHOCK LOVE HELL YEAH

  • @kmcsciguy
    @kmcsciguy 2 месяца назад

    I saw that “dubious food” reference

  • @Speed001
    @Speed001 2 месяца назад

    Cool

  • @MrMetro-mt5qv
    @MrMetro-mt5qv 2 месяца назад +5

    I want the mutant ability to teleport.

  • @sidhantvarshney4185
    @sidhantvarshney4185 2 месяца назад +3

    Yaaay I'm a mutant......which I already knew tho 😅

  • @malkum77ify
    @malkum77ify 2 месяца назад +2

    To me my X-Men!

  • @rayfwu
    @rayfwu 2 месяца назад

    I have a mutation where I don't get armpit or foot odor.

  • @dillonqaphsiel7977
    @dillonqaphsiel7977 2 месяца назад +1

    Based

  • @andrew24601
    @andrew24601 2 месяца назад +6

    I’m so happy that you chose a queer black person to host this series 💕 It makes me feel welcome in STEM

  • @malkum77ify
    @malkum77ify 2 месяца назад +1

    You should have used the X-Men animated series theme music! LOL

  • @LeandroFTW
    @LeandroFTW 2 месяца назад +1

    I can destroy milk and hot foods.

  • @Mojud_Zikr
    @Mojud_Zikr 2 месяца назад +5

    After knowing the seriousness of Climate change and reading many philosophers & religions, I guess, we need to become Vegan asap. It's already too late.