We’re full of bacteria!: Crash Course Biology #38

Bacteria often get a bad rap, but they’re some of our best partners in science and medicine! In this episode, we’ll explore what bacteria are doing with their DNA - including how they can trade it around. We’ll learn about chromosomes and plasmids, gene expression and recombinant DNA, and how E. coli are used to make insulin.
Introduction: The Microbiome 00:00
Prokaryotes & DNA 1:33
Plasmids & Horizontal Gene Transfer 2:44
Insulin 4:49
Gene Expression 6:30
Dr. Rebecca Lancefield 7:54
Review & Credits 9:05
This series was produced in collaboration with HHMI BioInteractive, committed to empowering educators and inspiring students with engaging, accessible, and quality classroom resources. Visit BioInteractive.org/CrashCourse for more information.
Check out our Biology playlist here: • Biology
Watch this series in Spanish on our Crash Course en Español channel here: • Crash Course Biología
Sources: docs.google.com/document/d/1G...
***
Crash Course is on Patreon! You can support us directly by signing up at / crashcourse
Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
Leah H., David Fanska, Andrew Woods, DL Singfield, Ken Davidian, Stephen Akuffo, Toni Miles, Steve Segreto, Kyle & Katherine Callahan, Laurel Stevens, Burt Humburg, Perry Joyce, Scott Harrison, Mark & Susan Billian, Alan Bridgeman, Breanna Bosso, Matt Curls, Jennifer Killen, Jon Allen, Sarah & Nathan Catchings, team dorsey, Bernardo Garza, Trevin Beattie, Eric Koslow, Indija-ka Siriwardena, Jason Rostoker, Siobhán, Ken Penttinen, Nathan Taylor, Barrett & Laura Nuzum, Les Aker, William McGraw, Vaso, ClareG, Rizwan Kassim, Constance Urist, Alex Hackman, Pineapples of Solidarity, Katie Dean, Stephen McCandless, Wai Jack Sin, Ian Dundore, Caleb Weeks
__
Want to find Crash Course elsewhere on the internet?
Instagram - / thecrashcourse
Facebook - / youtubecrashcourse
Twitter - / thecrashcourse
CC Kids: / crashcoursekids

[@williambilyeu9801]

Bacteria Street Boys! 😊 That's a terrible pun! 😅 I love it! 😂

[@alisutherland1103]

If we could get a whole microbiology class that would be awesome.

[@EhrenLoudermilk]

It just blows my mind this stuff is available for free. Thank you

[@Velociter]

I've been loving this series! It's making me love biology even more

[@malkum77ify]

Recombinant DNA has the potential for treating congenital diseases such as cystic fibrosis and sickle cell anemia. It has the potential to fix genetic errors. They are already early signs of being able to fix sickle cell anemia in some recent trials.

[@Caterfree10]

Hell yeah Miles Morales rep for the Spider-Man reference! Absolute fave spider person tbh. 💜✨

[@LynHannan]

The new Insulin in the 80's did not suit my maternal Grandmother, it didn't "play well" with her other meds for heart and depression at the time. She was having hypos almost weekly, multiple hospital stays for all her problems each year - it was as if all of her problems were magnified, and she was on a CONSTANT roller coaster of symptoms of all her health problems. But in Australia, there was no going back to the "pig Insulin" as it was no longer available in the country. She died only nine years later at 72. I know she was one of a minority, but it still doesn't excuse blanket decisions by government - they should have left it for the customer and their Dr to decide which was better for them. It just goes to show how convoluted Insulin really is, it affects way more than just the transfer of Insulin into cells. Besides my 2 cents worth, a great episode! I was not aware of the different transfer mechanisms of DNA in bacteria, thank you!

[@SonyaDyson]

My 10 year old son and I watch this every night. Thank you

[@erie517]

Thank you for this series! You’re awesome 😊

[@iza595]

Thank you so much for these videos! they are so helpful

[@murtalaabbaadamu]

This is really helpful. Thanks.

[@dhedgpeth]

Keep up the great work! Love all of thes videos!

[@RylanBooth]

No way you got the bacteria street boys 😮

[@tomahawk27]

these videos are great!

[@leslieelainehermans4382]

I love the jellyfish lava lamp 😄

[@gailaltschwager7377]

Thank you!

[@CordBrockmann]

Neat video but I have a few questions: Aren't Archaea there own domain of life, separate from prokaryotes and also more closely related to eukaryotes? And doesn't recombinant insulin that was synthesised in bacteria require extensive chemical modifications to properly function? Which is why it better produced in yeast.

[@isabellaxclark]

Very informative. 🤗

[@jbf5117]

Love it!

[@kchiem]

9:36 What brand jellyfish lava lamp is that?

[@niloy_root]

very good

[@gameboygaming450]

i love this

[@Didomate]

Cool video

[@BasslineMusicGroupOFFICIAL]

Make more vids pls

[@stax6092]

I once transferred my Jeans horizontally.

[@sussekind9717]

I thought an entomologist was someone who studied insects?
Although I don't know what they call a bacteria studying scientist - Dr. Bacterius?😂
Just busting your chops, good video. Very informational.

[@headsworthtg3585]

the eukaryote is grey, is that on purpose?

[@theeutecticpoint]

plasmids, but no cheeky bioshock reference, I'm surprised

[@gameboi20]

Who’s ready for new CC pilot?

[@Toutachifaux]

🤗🤗

[@y.etosha]

Bacteria street boys hahaha

[@flexn01]

💫💫

[@Davlavi]

Very cool and I first!

[@heatherbowman9450]

593 likes!💟💟💟💙💙💙

[@docarii]

if I’m composed of more organisms than the cells that make me…
am I… me? or is it we..? who am we..?

[@zonius100]

No

[@quocthang7857]

.

[@fairygurl9269]

✌😁

[@tindansandow8823]

Noice

[@MCMarioG99S0ccerFTW]

Firsttt

[@user-vy9sv6fh4r]

First

[@willemvandebeek]

first

[@malkum77ify]

Mutation are the keys to life.

[@michaelmayhem350]

By the time you've read this, you've already read it.