Respiratory physiology: how is the transport of gases (O2 and CO2) in blood?

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  • Опубликовано: 9 июн 2021
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    It describes how O2 and CO2 gases are transported in blood. The two ways in which oxygen is transported are described: 1- free or dissolved (in red blood cells and in plasma) and bound to hemoglobin (within red blood cells). The vital importance of hemoglobin (Hb) in the transport of O2 in the blood is highlighted. It also describes the structure of Hb (alpha and beta polypeptide chains, Heme group, iron [Fe], with the binding sites for O2) and what the hemoglobin oxygen saturation curve is like as a function of pressure. arterial oxygen. In addition, the three forms of carbon dioxide transport are described: 1- dissolved or free both in plasma and within erythrocytes, 2- bound or bound to carbamino groups of hemoglobin (as carbaminohemoglobin) and of plasma proteins , and 3- as bicarbonate (HCO3-) both inside red blood cells and outside in plasma. Finally, the volume of O2 extraction and the volume of delivery (release) of CO2 from the tissues and the ventilation-perfusion relationship (rel. V / Q) are described.

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