Immune Response Explained: T-Cell Activation

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  • Опубликовано: 29 дек 2020
  • Every day billions of tiny invaders called pathogens want to make our bodies their new homes. Luckily, we have a powerful army of specialized organs, cells, and tissues that work together to protect us. This is your body's immune system. Within this complex system is type of lymphocyte called a T-cell. This video will introduce you to Helper and Cytotoxic T-cells, and describe the mechanism by which they are activated when encountered by a pathogen. If you wish to know more about this remarkable process, make sure to stay tuned so we can demystify T-cells together!
    This video was made by Demystifying Medicine students Navroop
    Gosal, Jiayi Mo, Xiuyuan Song and Sara Warsi, in collaboration with the McMaster Demystifying Medicine Program.
    Copyright McMaster University 2020
    References:
    Cavanagh, M. (n.d). T cell Activation. British Society for Immunology. Retrieved from www.immunology.org/public-inf...
    Gaudino, S. J., & Kumar, P. (2019). Cross-talk between antigen presenting cells and T cells impacts intestinal homeostasis, bacterial infections, and tumorigenesis. Frontiers in immunology, 10, 360. doi.org/10.3389/fimmu.2019.00360
    IQWiG (Institute for Quality and Efficiency in Health Care). (2020, July 30). The innate and adaptive immune systems. Retrieved from www.ncbi.nlm.nih.gov/books/NB...
    Sauls, R. S., McCausland, C., & Taylor, B. N. (2019). Histology, T-Cell Lymphocyte. In StatPearls [Internet]. StatPearls Publishing.
    Smith-Garvin, J. E., Koretzky, G. A., & Jordan, M. S. (2009). T cell activation. Annual review of immunology, 27, 591-619. DOI: 10.1146/annurev.immunol.021908.132706
    Storey, M., & Jordan, S. (2008). An overview of the immune system. Nursing Standard, 23 (15-17):47-56. DOI: 10.7748/ns2008.12.23.15.47.c6738

Комментарии • 61

  • @giselleshane9715
    @giselleshane9715 Год назад +8

    "maybe they won't notice"
    "they noticed"
    10/10 video, A plus, all stars

  • @2tuff550
    @2tuff550 2 года назад +54

    The fact that we know how they work is mind blowing

    • @anotherpointofview222
      @anotherpointofview222 2 года назад +9

      Exactly. The combination of the fact that these functions exist and that we have the capability of mind to observe and understand their existence and purpose is evidence of a Creator to me. A Maker of man. Most importantly that we are made in his image (likeness of mental capability).
      Nothing to do with institutionalized religion.

    • @fredhuerta9514
      @fredhuerta9514 2 года назад

      @@anotherpointofview222 Amen to that! Praise the Lord Almighty!

  • @TheChickswithdix
    @TheChickswithdix 3 года назад +31

    I've been reading about T cell immunity, buy this video really makes you understand the process much much better! Keep up the good work so us normal peiple can better understand human biology!

  • @boofang10
    @boofang10 2 года назад +4

    BRILLIANTLY explained !! 👍🏻👍🏻

  • @nesrenedres9193
    @nesrenedres9193 3 года назад +4

    Great
    Thank you for all your hard work on this

  • @nellivakhitova2005
    @nellivakhitova2005 Год назад

    Thank you for this video! It helped me a lot!!

  • @captaincc5700
    @captaincc5700 Год назад

    Thank you so much for this video, it was very helpful!

  • @jessicaschabatka8377
    @jessicaschabatka8377 3 года назад +2

    thank you, this was helpful

  • @abigailbermudez1796
    @abigailbermudez1796 8 месяцев назад

    thank you so much for clarifying!

  • @syb_764
    @syb_764 Год назад +3

    I’m taking a biology lecture & this really helped. I still need to study a lot but I have a better idea now!

  • @emelerkiran8574
    @emelerkiran8574 2 года назад +10

    Thank you so much for this video. Helped me a lot with my exam I have this week!

  • @hugofriberg3445
    @hugofriberg3445 Год назад +1

    It’s amazing to see how advanced our bodies have become just by evolution!

  • @julieaono35
    @julieaono35 3 года назад

    Great video

  • @KpfoodZ
    @KpfoodZ 2 года назад +1

    Very helpful❤

  • @alishmansuri4319
    @alishmansuri4319 Год назад

    thanks a lot now i finally undersrand this topic❤ ❤😊😊

  • @RaymondChen-jk6bx
    @RaymondChen-jk6bx Год назад

    Great vid!

  • @IIkIllswxtch
    @IIkIllswxtch 2 года назад +1

    I’m watching this while I’m sick 🤒

  • @jmo8a_veda
    @jmo8a_veda 2 года назад

    i had a swollen lymph node on my left side of my throat they wouldnt let me see what it was usually put to sleep to complete surgery anyway it was dysmorphed

  • @Riasat202
    @Riasat202 3 месяца назад

    I don't think we appreciate the body's ability to produce specific antibodies for literally a trillion unique potential antigen epitopes. Almost incomprehensible!

  • @sandraslattery6708
    @sandraslattery6708 2 года назад +14

    This video is so great, thank you! Also FYI, maybe you could consider de-essing the voice a little bit? Some of the sibilance is very harsh :o) Otherwise, very nicely done!

    • @jessicabaileyatsml
      @jessicabaileyatsml 2 года назад +1

      Oh no! You broke the ceiling. Now that's all I hear

    • @spacefitness3821
      @spacefitness3821 6 месяцев назад +1

      Great video, but I scrolled down to see if anyone else commented this. So much sibilance.

  • @ericafisette160
    @ericafisette160 2 года назад

    We win BIG! 🏆 🏆!

  • @il3mendo
    @il3mendo 8 месяцев назад

    Tcr beta and gamma- and tcr beta and gamma + are common in the duodenum ?
    Nk if i am not wrong belongs to the innate immune system.
    Dn cd4 or Cd 8 are immature or are a consequence of autoimmune disease ?

  • @michael5147
    @michael5147 2 года назад +9

    *me not understanding a thing*
    “this was a very simplified version of how to explain t cells”

    • @wifi-YT
      @wifi-YT 2 года назад

      You’re right to be confused by a very confusing presentation.

    • @anomalyp8584
      @anomalyp8584 Год назад

      The immune system and its function is one hell of a thing to understand. Repetition is key to understand.

    • @anomalyp8584
      @anomalyp8584 Год назад

      @@wifi-YT It definitely is not.

    • @wifi-YT
      @wifi-YT Год назад

      @@anomalyp8584 I disagree. I think Michael is right to be confused. This video is extremely confusing.

    • @anomalyp8584
      @anomalyp8584 Год назад

      @@wifi-YT what is so confusing to you?

  • @alastoria_va
    @alastoria_va 9 месяцев назад

    I wonder how many students you helped

  • @phillyry
    @phillyry 2 года назад +4

    Your voice hisses a lot when u pronounce the letter S

  • @stun5700
    @stun5700 2 года назад

    I know love the T cell

  • @switchsmip1962
    @switchsmip1962 5 месяцев назад

    what ab step 2 of the activation of the other t cells CTL

  • @daphne201239
    @daphne201239 2 года назад +1

    Now... How can we increase these helpers, naturally?

    • @daphne201239
      @daphne201239 2 года назад

      Nevermind... I found the answer right after I commented.
      ruclips.net/video/FGtS_h_xTuc/видео.html

    • @n1msu
      @n1msu 2 года назад +4

      @@daphne201239 your body will boost what it needs when it needs it. Of course nutrition is vital, but your blood isn't going to be swimming in killer t cells etc unless it's vital. Immune response is a major part of what makes one feel ill during a viral infection etc. The body is a finely balanced machine, you're not going to increase the helpers unless you're constantly infected I'm afraid to say.

    • @gutadin5
      @gutadin5 2 года назад +1

      Zinc 35 to 50 mg
      Melatonin 3 mg at night
      Mushroom extracts

    • @julioalexo
      @julioalexo 2 года назад

      Good question; I've no answer. One thing I'd focus is if an 'over suscription' of T Cells could be counterproductive.

    • @stephaniem7915
      @stephaniem7915 Год назад

      Thymosin alpha 1 peptide

  • @virgil1981
    @virgil1981 Год назад

    Resident evil stuff :)

  • @vinegaronice122
    @vinegaronice122 2 года назад

    All I can think while watching 8s Resident Evil

  • @yip2454
    @yip2454 2 года назад

    1.25x

  • @timmytee734
    @timmytee734 2 года назад +9

    Her hissing s-es are so irritating to my ears!!

    • @Pixelgamiing
      @Pixelgamiing 2 года назад +2

      Appreciate that she is explaining a topic in a very clear way with great animations

    • @timmytee734
      @timmytee734 2 года назад +1

      @@Pixelgamiing I don't know what kind of a submissive slave you are and how your owner tells you what to appreciate for but luckily I'm free to decide myself what to appreciate and what not to like.

    • @saisree3638
      @saisree3638 2 года назад

      😂