Regulation of Insulin Release and Insulin Action

Discusses the mechanism that causes insulin release from the beta cells of the pancreas and how insulin causes uptake of glucose into cells.

[@abigailgarza8179]

Perfect. Even for a medical student, this was the perfect level of detail for a quick refresh (studying diabetes pharm right now and remembering this pathway is key)

[@tridiascarlett4708]

I love your explanation.

[@pinkpanther9272]

Thank you so much for simplifying the mechanism!

[@mahtab1933]

So smoothly explained... I love it

[@irijnasir5126]

Thaaaaaaak uuu sir! I spent half hour to find that particular concept, and finally u made it clear to me

[@medicalscience1528]

THANK YOU SO MUCH. this is what I wanted to know briefly .

[@sidraanwar7083]

Thank u so much for simplifying this mechanism !!!

[@dannyzamir7675]

Great and simple video! Thanks!

[@nadiacharafi8815]

simply explained! thank you

[@ZamiraTawfiq]

very well explained.. thanks!

[@nourassani5589]

Thank you for simplifying this mechanism💙

[@user-rq1qv8lr3r]

Thank you! this helped so much for my pathophysiology exam.

[@clxra16]

Wow u explained it smoothly!!! Thank you!!

[@infinityaxeman]

thankyou. This has been very helpful I'm glad lockdown came after this video was released

[@elfassimariam250]

Right to the point, thank you!

[@nathananyimahmensah1104]

very simplified and easy to understand. thanks😁

[@themasterkirkfurter3]

thank you for this!!

[@momentswithmauntey3360]

Thank you so much!

[@user-ud8md2dk7c]

Really helpful, thanks~

[@rubynguyen7705]

Thank you for your explanation, it's logical and so easy to understand :>

[@sarasawsaw5207]

Thankkk you so much!!!!❤❤❤

[@abdulroqibbello6591]

Very succinct, thanks a lot

[@ujjawalmishra858]

Wonderful explanation 👍

[@prashantshrimali1767]

you are amazing ,thank you for making this video 🙌🙌

[@imanemorjane6748]

amazing simple concise video

[@hemalatha1535]

Explanation Was very crisp and clear.. giving all the required info

[@physiopathopharmaco4190]

Glad you liked it

[@nynmlg2299]

Thank you

[@mohsenkhalid4441]

Great videooo..
Why don't you make videos for a complete system wise topics for First aid?

[@elifsumeyraerdemir2988]

That's very usefull video. Thank you sir

[@Smiling_medico]

Nice video concept clear

[@mobeensipra8152]

thnk u make it soo easy

[@tony___3077]

This made a desperate med student v happy inside

[@sahraabdi1152]

Thanks 🙏

[@user-pradeep_2207]

Thank u so much sir

[@hananechebicheb9945]

thank you it is a good videos

[@ruthannfacey7586]

Great Video ,Thank You So Much !!!!!!!!!

[@physiopathopharmaco4190]

Glad it was helpful!

[@Hanan-wq1op]

Thank u sir .May Allah protect you

[@giorgosgranitsiotis]

thanks thanks thanks thanks thanks thanks thanks thanks thanks thanks thanks thanks

[@vineethavakkapatla6873]

Nice video

[@imanemorjane6748]

helpful and light :)

[@muhammedabdulmecid5818]

thanks

[@silviagurkova2442]

Thank you very much! The best explanation! You should teach!

[@physiopathopharmaco4190]

Glad it was helpful!

[@picklepickle1629]

Thx 👍🏻

[@alexkasinskas851]

brilliant

[@tharindudhananjaya1036]

Good content

[@anintyasw7275]

Thank you so much, sir, and all of the people that has made this video to happen. may god bless u

[@physiopathopharmaco4190]

That’s very kind thank you

[@homeenertainment7709]

Such a hard topic made so easy.Thanks a lot...

[@physiopathopharmaco4190]

You’re welcome- glad it was helpful

[@Afshu97]

thank yoy

[@muygechlim6586]

Thank you so much

[@physiopathopharmaco4190]

Very welcome

[@MichelleLathrom]

I love the illustration. But what about in the case of an insulinoma? Where the insulin production has nothing to do with how much or how little glucose there is in the blood. Or in the case of a reactive insulinoma or even beta cell hyperplasia where the excessive insulin is provoked by glucose. What starts the process when no sugar is there and what makes the process excessive in its response?

[@aakrutipatel5137]

Thank you sir. This video cleared all my doubts.

[@physiopathopharmaco4190]

You are most welcome

[@pratyaychatterjee7055]

Thank You Sir.
Love from Kolkata,India.

[@physiopathopharmaco4190]

You’re welcome

[@pkvideoofficial8748]

Thanku so much🙏 your videos are very helpful to learning

[@physiopathopharmaco4190]

So nice of you

[@user-sd9rc6qt7z]

Danky😊

[@magicpearl3060]

So good 👏🏼👏🏼👏🏼

[@physiopathopharmaco4190]

🙏 Dania - all the best to you

[@fereshtahkhoshbakht1999]

great thank you

[@physiopathopharmaco4190]

Thanks for the comment- all the best

[@pedrorodrigueztube]

So beta blockers also block insulin release?

[@TheLingnerFamily]

Okay here's my question. Hopefully the body will fill its glycogen stores in the liver and muscles, and then once full deposit excess as fat. Is that how it works? And if so how does that work? There must be some kind of communication level which would allow for the insulin receptors to activate in the fat when the insulin receptors are closed in the liver and muscles.

[@raghadj6617]

Great thanksss

[@physiopathopharmaco4190]

You are welcome

[@maxwellbarnaby]

But then what happens to the Amylin in the blood?

[@reemabuali3104]

Thank you
that's help me alot

[@physiopathopharmaco4190]

Thanks for the comment Reem - best of luck to you

[@physiopathopharmaco4190]

Awesome- you’re very welcome 😀

[@Snigdha2409]

Good

[@smkishtiak]

Thanks

[@physiopathopharmaco4190]

You’re welcome

[@TheRainlswet]

HI! I'm a little confused about WHY the Ca²+ channels opening leads to Ca²+ influx. The closing of the K+ channels leads to a higher intracellular positive load, so why would positively charged calcium ions go against the load gradiënt?

[@physiopathopharmaco4190]

It follows the law of diffusion - Calcium is in higher concentration outside the cell, so it comes in

[@Hudamk99]

Amazing ♥️😍

[@physiopathopharmaco4190]

Thank you! Cheers!

[@Markolio95]

good job

[@physiopathopharmaco4190]

Thank you

[@user-dh3vs5cm8b]

❤❤❤❤❤

[@azizah8766]

Amazing amazing thank you 🙏 💕

[@krisztianlenart3425]

Hi, thanks for sharing this. My question is, if there is too much insulin production, does this mean that the insulin receptor is malfunctioning and not sending signal back to the pancreas to stop producing insulin? Or something else is responsible for that? Thanks in advance.

[@physiopathopharmaco4190]

Yes too much insulin can cause the insulin receptors to become dysfunctional and less sensitive to insulin. This can lead to type 2 diabetes.

[@krisztianlenart3425]

@@physiopathopharmaco4190 thanks for answering. If you do the correct diet and stop overloading the receptor, can the receptor recovers over time (maybe with supplements or other way to boost its recovery)and signal the pancreas as it should? So it won’t food the body endlessly with insulin every time someone eats? Or is that regulation has more to do with the Beta cell’s K+&Ca charge regulation? Thanks again.🙏

[@ianokello778]

Actually to me I think increase in insulin secretion leads to low blood glucose levels, hunger,sweating, irritability and double vision yeah that's what my brain and logic Tells me

[@Pathology92]

Thank u so much! May ALLAH bless you!

[@physiopathopharmaco4190]

Very kind - thank you

[@user-uh9uv2yw9h]

AMEEN.

[@hananechebicheb9945]

would you put the address gmail for contacting ?

[@liliannguyen9502]

I don’t understand anything:)))

[@l77bt]

Me too 😂😢

[@MimePka]

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[@dyanalekha8186]

Thank you so much!

[@jalalalrez7306]

Thank you

[@physiopathopharmaco4190]

You're welcome