Unboxing the craziest thing I own
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- Опубликовано: 18 июл 2023
- For the longest time, a dream of mine was to have my own tabletop NMR, and in 2021, I was finally able to get one.
NMR stands for nuclear magnetic resonance and it's a machine that helps determine the structure of molecules.
The first time I used it was when I turned plastic gloves into hot sauce: • Turning plastic gloves...
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Nile talks about lab safety (Chemistry is Dangerous): • Chemistry is dangerous. 
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I like to imagine that Nigel lives in a giant laboratory that's painted to look like a house with trees around it, and the FedEx guy just hasn't noticed the giant lab yet.
I like to imagine you as a fellow dexter’s lab fan
@@Slug_Boots you imagined correctly.
Basically Ohio 💀
Pinky, you know what we are going to do today?
Like invader zim
In case you’re wondering, he uses this machine in the turning gloves into hot sauce video. About 44 minutes in.
Thank you
THANK YOU SO MUCH!
75k bucks and he turns wha... well, no real surprise here.
also in paint thinner to cherry soda to measure benzaldehyde. rewatched that one on snapchat today and was amazed he had an NMR machine. didnt know there was an unboxing for it. did he ever announce this channel?
@repentandbelieveinJesusChrist1 amen 🙏
NileRed: *buys an expensive, heavy piece of lab equipment*
Also NileRed: I don't know what I'm looking at.
Very quietly at the end "maybe I should read the instructions"
That's his cameraman friend you silly
edit: nvm he does in fact not know what he's looking at
"I just thought it would look nice this all the other stuff in here"
It's gotta be some kind of loot create for chemists
It's kind of upsetting and a pet peeve for me, because many of us 'meager' scientists have university labs that are 40+ years old and have to try to build our own equipment, or repair it, out of junk to be smart with funds and this guy, who is graced with money to buy this expensive and very nice equipment, plays a "game" where he sees if he can break it by plugging in cables that may, or may not, be rated for it with the same kind of 'rich kid' energy of a teen distracted driving his parents 150,000 car making a tiktok video. It just looks bad and makes well paid scientist look irresponsible and wasteful. But that's what sells nowadays ig. Anyways, no true hostility towards you Nile, just your behavior. Honestly, congratulations on your good fortune in life. I hope that you continue to do well, but having callous disregard for these things which took true geniuses to design these machines, means that by the golden rule you want us to have callous disregard to your work, right?
He cloned himself and didn’t even talk about it. What a genius
This is getting out of hand. Now, there are two of them!
but seriously tho thats his bro
Yeah that's NileGreen
@@The_Black_Hole If women don't find you handsome, they'll at least think you're handycapped.
Two is one and one is none. Nile knows the dangers involved and has a backup ready to go when he eventually drops an ampule of bromine.
The only time my classmates and i tried to use an NMR to id contaminants in industrial monomers… it was a unit the size of a fridge in it’s own desk.
Most NMRs are the size of a fridge for good reason. Small bench top NMRs like the one Nigel got are not very powerful and can't get very high resolution spectrums. (you wouldn't be able to publish any data from a bench top nmr) the reason is because the larger NMRs use a supercooled magnet whereas the bench top ones use just a standard magnet, so the magnetic field is nowhere near as homogeneous and precise
It's like a giant spectrometer and this reads the magnetic fields around atomic nuclei, it is like a hyper-spectrometer!
Fyi its spelled (hyper) not hiper lol
@messier8768 go ahead, tell him his username has 2 first names
i hope it doesn't cause a resonance cascade scenario.
@@YO-BIZZYhe's a highly trained professional. We've assured the administrator that nothing will go wrong.
While I was in university we performed NMR analysis but it was on very large spectrometers and the electromagnet was cooled in liquid helium and nitrogen. But there are those tiny table NMR. How could those work ? I'm lost 😅.
By the way, you were the one who convinced me to study chemistry ❤
I used this same exact H-NMR in my undergrad lab. The resolution won’t be NEAR what you’d see using yours, but it can give you a decent idea if you have what you think you have (provided your compound is relatively small and pure - like no more than 2 kDa)
This one uses a solid state magnet, but it's resolution is really really poor compared to the NMRs using superconducting magnets like the one you used
Ahah ok, thanks for the precision 🤗
The big spectrometers with helium-temperature superconductors are in the hundreds of MHz range. These little guys are 60 MHz and use a room-temperature magnet. If you believe the sales guys (saw them talk about it at a conference), it's easily portable and can be recalibrated easily to give reliable spectra anywhere you go. They designed it with teaching labs in mind - in fact, the tube hole goes all the way through so if a student breaks off a tube in the instrument you can tip it on its back and push the broken tube out. Pretty cool piece of kit for a particular niche.
This must be whats in the room I walk by all the time on my way to lab. That Or I’m passing something else lol
That's a nanalysis 60e NMR spectrometer, I guess this thing goes for around $50000, pretty impressive.
was looking for this, thank you!!
I first heard "This is the En-em-a machine."
@@CookingWithCows he's canadian, sometimes he says shit weird lol
@@CookingWithCowsthatd also be pretty cool😂
Dropping 50K on a single piece of equipment he probably wont use all the time.... yeah he must be a millionare.
I love how it just ends with Nile saying
"I actually have to read the instructions"
I’ve been watching your videos for years but now that I’ve started working in a chemistry lab I can actually appreciate how crazy that thing is. We have to use a step stool to put our samples in the NMR. What’s funnier is how both I and the grad student I work with got into chemistry from watching your videos so thanks.
Yeah, but the one you get to use is way way better than this little one. Bench top NMRs have very bad resulution compared to the big standing ones
Where are all his videos? I only see 2 (besides shorts)
@@mmm555m Nigel has like 4 channels
@@mmm555mnilered and nileblue are what you're looking for
That "I dont know what im looking at" was the most relatable thing ive ever heard from Nile
RGB lighted lab equipment unironically goes hard
What a time to be alive.
Imagine playing Skyrim on a lab machine 😂
Imagine someone casually carrying a 130lb briefcase with one hand. Why would they put a handle on this
Maybe because at a high price they don't want anyone to miss a thing.
...or they've designed it for Bodybuilders, Chuck Norris and Terminator.
...or just because they can.
The crate probably weighs ~15 lbs, so it's only 115 lbs
He literally said it’s not even close to that. It’s likely 55-60
It is probably a standard case for many different potential types of equipment, fitted with custom foam for this particular piece of equipment. If some other company uses the same case with different foam to package something that weighs less, they would want the handle. So the company that makes the case puts a handle.
@@conor7154It's not a Pelican, but an equivalent brand (the branding on the top of the case appears to just be a case manufacturer)
I love how he didn't even tell us what it was
BUT IT HAS LED LIGHTS XD
Love nile and the team so much 😂😂
He says it during the first seconds 0:01 NMR machine
NileRed gamer laboratory let's gooooooo
@@aardengNMR means what? And Does what?
NMR could mean Nitrogen Metabolic Resonator for I know, and I don't even know what that means
@MozzaBallBill Nuclear magnetic resonance machine, it's for analyzing different materials and finding out their composition...
@@MozzaBallBillit's literally an MRI, but the true name is NMR, and chemists use it to determine a chemical's structure.
This amazes me. I remember the NMR machines where I used to work and they were huge things in a quite big lab
A small NMR in other words.
60 hz vs 800 hz
@@wingl5841 mega hz
I mean yes, they are wildly different in frequency, but I just didn’t knew there were such small models like this
@@smokeduv I agree. It's crazy that it is that small. It will be fairly low resolution but still probably good enough to confirm the compound and the purity.
NMR has come a long way. When I was in undergrad ~25 years ago, those things pretty much required their own room.
I'm a physicist who uses EPR almost every day. I adore magnetic resonance! I was so excited to see this pop up.
Can you explain what it does?
@@davidshaw164at least we have something to Google. Better than what Nigel left us with.
I need a degree just to understand Electron Paramagnetic resonance 😊.
If I need to use this in paleontology I will find someone else to use it 😁
@@davidshaw164 Basically like NMR, but with electrons instead of nuclei
@@antares8826that means nothing to me. I need to go back to my dictionary of acronyms.
How come no one told me there was *another* NileRed channel?
Also, petition to change the name to another color (Nile____)
Yellow for piss experiments
@@tbounds4812 Yellow for Explosions&Fire's love of yellow chemistry
nilegreen, RGB
@@scottydog6713 we already have nilegreen
Great to see Nigel is still here
Freight ships by size, and then the size is used to estimate the “weight” no matter what the scale actually says. (I ship guitars all the time, it’s really funny that an 4kg guitar in a 3kg case is labeled “25kg”.
Dimensional weight is what you're talking about and it only applies if what you're shipping is bigger than it is heavy.
Bigger than heavier? Riiight
@@hemlockVape yes, if you ship a pound in a 36" X 36" X 36" box your going to pay for 30 pounds of dimensional weight. If you put it in an 10" X 10" X 3" box you'll pay for a pound.
@@Kandralla Bigger than heavier. 🤔 👍🏼
@@hemlockVape you knew what was meant. Find less dumb hobbies.
I love how he says “if it fits, you plug it in!”
While he already did this exact thing with some other wildly expensive machine and it almost burst into flames or something
I love the work of your cutter its just on point sometimes
Use tin snips to cut your banding to avoid knife injuries. Also, while working in warehousing and industry I've seen (steel) strap mess people up. Wear your PPE and don't stand in line while cutting it.
This has been an unsolicited safety brief
@@YO-BIZZY I'm mostly joking in the manner that a safety guy would say it.
But if the banding is really tight, I've seen people get lacerations if the band whips back and catches them. Some of them have been pretty nasty and required stitches. We also prefer to use tin snips to cut the band because then you're not snapping a sharp knife back twords you.
Underrated comment, seen deep laceration once from banding at work
I used a unit just like that in college! Super easy to use and intuitive. Hope it has been working out for you!
Wow, it's so tiny, the one we had at University was about the size of a room
Very nice, i can wait for cool projects your try out with this new machine
I guess the "60" is the frequency, so it's presumably a 1.4T machine - pretty impressive for such a small package. Back when I was using this stuff we had a 100MHz machine (Bruker) that needed a liquid He cooled cryomagnet and took up most of a room.
The same company makes 100MHz ones as well that aren’t very much bigger than the 60 he got, those things are truly a feat of engineering
My dad is the director at an NMR laboratory. When I was 4 or 5, I told people he “drew scribbles on the computer” because that’s what his job looked like to me.
18 years ago i did some testing with benchtop NMR`s at work, so funny you actually bought one!
Nerding out on your nerdiness Nile, thx!
NileRed Subscribers: Hey, what’s up?
Nigel: NMR now, new channel, you?
NMR is a widely used spectroscopic method to deduce chemical structure. It has become a central tool for chemistry, medicine, materials science, and engineering.
NMR examines the structure of molecules by measuring how certain atoms behave in a magnetic field. It provides information about the arrangement of atoms in a molecule and helps identify different compounds. This technique is widely used in chemistry and biochemistry to study the structure of molecules, including proteins and other biomolecules.
It helps us figure out what things are made of and how they interact with each other. It's like a special fingerprint that tells scientists the secrets of molecules.
The machine listens to the responses from the atoms and creates a kind of "fingerprint" graph called an NMR spectrum. This fingerprint shows peaks at different positions, and each peak tells us about the atoms and how they are connected.
By looking at the NMR spectrum, a chemist can identify the different atoms present, figure out how they are linked together, and understand the overall shape of the compound.
Trasformer noises on opening the box got a good laugh out of me. Excited to see more from this channel!
I got one of these ten years ago. I’m sure the electronics have changed as well as the operating system. I’m really impressed with whaat can be done with it. My understanding is that the newer ones can run more than just proton NMR.
The one he got only does proton but you can get them with everything from tritium to phosphorus and a whole lot more now
congrats on your newest toy!
I'm sure we'll all enjoy it immensely
Those are like $30k and up aren't they? Happy for you bro!
When I was in college in the early 90’s my Chemistry Professor took us into the room with the NMR machine. It was literally as big as the room (probably 15x20)
Love your unboxing videos.
This warms my analytical chemistry loving heart
I'd love to know where you got it and how much it ran you - ive been dying to own one.
Very cool!!!
"WOOOOW! I don't know what I'm looking at."
My thoughts on every Nigel video.
I just love watching all these videos 😄
Love this guy , notice how he never even looked at the instructions , I only go to the instructions after things go wrong
Looking forward to seeing some nice NMR spectra
Ngl that carry case was the coolest one I saw in my life.
Plug it in if it fits is a terrible technique! 😂
FilmArray PCR system comes with a USB-to-RJ45 cable and if you plug that into the PCR, it fries the mainboard immediately lol.
That’s meant for the barcode scanner.
Oh what a cute little NMR. It's the size of a hat box. That's amazing, I had no idea they made them so tiny now. I guess you don't need a giant dewar of liquid helium to run this one.
This is awesome! 60mHz table top NMR machine?
That is the cutest little NMR I've ever seen! I love it! My university has a tabletop NMR that that they use for undergrad samples, but it's quite a bit larger.
Out of curiosity, what is the frequency?
Also, sometimes it's nice to be able to heat samples while you're running NMRs. For instance, if something is poorly soluble, heating it a bit allows you to get more of the compound in the sample dissolved and get better results. There are also times where you have something that might have hydrogens attached to the same atom that are somewhat fixed in position (for instance, some amines) at room temp, making them inequivalent, and giving really broad peaks that can be annoying to interpret. If you heat the sample, they're much nicer, sharper peaks to analyze. You can even run reactions IN the NMR tube, if it's something that doesn't need any workup or intermediate steps, if the solvent used for the reaction is available as a deuterated solvent, then monitor reaction progress and observe intermediates in NMR. This has the added advantage of requiring only tiny amounts of reagents, so you can see whether it's even worth doing on a larger scale.
We use the cheaper nanalysis benchtop NMRs in our labs at school!
Interesting. The NMRs I saw were the size of a small car, I didn't know they come in such small sizes too
It just has a lower magnetic field strength, I think most NMRs are like 5-600MHZ with cryogenically frozen magnets and everything, this one is only 60MHz
Last time I used this trick was with a portable AC and the instructions said “Let device sit upright and reach room temperature before use” and I was like “Oops”
I like how nile red got nile green to help out
It's been a few months but I now get why there is a sample warmer. Deuterated DMSO freezes below like 20°C and you can't record good spectra if your NMR solvent is frozen solid. My department solves that problem by simply keeping the reception room for NMR samples at 25°C.
I had SO MUCH fun using the NMR machine in college! Have fun!
Yeah lots of new electronics activate when you plug them in, but you still have to "turn it on", hence that bright green on button on the side.
Wow this is really compact. In the lab we had I think 3 - they were filling a room :D
I need a machine like that
I have a photo of my old lab manager in my camera store curled up inside a Pelican 1660.
While that case is large, it’s just getting started.
"Yeah I should... read the instructions.." lmfaoo he just like me fr fr
Damn THAT'S the guy who's been behind the camera the whole time? Awooga
its much smaller than the one at my school
just goes to show how innovative technology is
The "if the plugs fits it, plug it in technique" is how my coworkers broke all the Ohaus scales at work T___T
Is the "I should read the instructions" for me...😂😂
That is probably nicest enema machine I have ever seen
Very cool device and yet somehow already out of date, Q Magnetics are currently releasing a 125Mhz desktop NMR for roughly the same price as this 60Mhz one. However, i would absolutely not complain if i had either.
What model NMR is it? How strong of a magnet does it have?
Will you do a video showing us the Ins and outs of this NMR?
It's one these NMR machines!!
"You can't get it out"
Never doubt the determination of your camera man again
I imagine Nile to be the child that opens a gift and plays with the first thing in the box only to find out later that there are several parts.
This wasn't an unboxing, it was an uncrating.
What would you use to power your machines if there was a blackout? Thank you sir.
Bro I like your videos, and your personality is great people vibes, u do remind me of dexter laboratory though lol
Bro's flexing with that RGB NMR machine 💀
AYOO, The NMR really do be sounding like Perry the platypus
1:30
When I was in college (a long while ago), we had an NMR machine that filled part of a room. The professor wouldn't let us near it.
Wow! I've never seen a tabletop NMR. The ones I've used were HUGE.
i want to see some nmr action!!
"I don't know what I'm looking at"😂😂😂😂
pure unwarranted chaos
Wait, you can get NMR machine of that size. All I've ever used is machine taking half of the room
Bench top NMR, yep. It’s like 60 to 100 MHz.
Your room sized ones are 300 MHz to 1.2 GHz.
2:22 "if f the plug fits it, plug it in" is such a bad idea for those dc barrel connectors. there are so many different power ratings using the some size connectors.
Am waiting for that resonating dipole spin moment....! 🧐😉😅
The fact that they both said “I don’t know what it is”😂
Im always terrified of our NMR. Those magnets are strong
“This is the craziest thing I own.”
“..Well what is it?”
“The craziest thing I own.”
Oh hey, a new channel. Cant wait to see more.
How was I not subscribed to this channel yet?
Somehow I thought an NMR machine would be bigger, but this is still extremely hype. I can definitely see it getting a lot of use.
This is a low resolution 60 MHz unit. It does not use superconducting magnets like the fancy ones. It fits on a bench top and can give you a low res idea of the compound you made. Nice NMR machines require large dedicated spaces and full time technicians just to maintain them. They also cost in the hundreds of thousands of dollars
"Whooooa... I don't know what I'm looking at." 😂😂😂
Nothing better than unboxing scientific equipment
I still don’t know what I am looking at there.
Bro is gonna start his own DARPA at this point 😂
Love your videos was watching this on break had to get back to work what is it ?
Wait, is this footage from a while back? Coz i swear I've seen you use this machine a few times
MAN THAT WAS CRAZY
Im in orgo 2 right now and im pretty sure that is the exact one we have in the lab at my university 😂
Nigel's lab is insane.
Looks like the most premium blender you can get
Now you need a mass spec