@@michaelwerkov3438 The anhydride is hard to get since it's used to synthesize heroin.. In small amounts it'd be in something like aspirin synthesizing kits i believe. But you can have similar results or just a little less potent with just acetic acid & some catalyst I believe. There's also a plant that you can make the anhydride of, perhaps all of it is made from plants. I find this stuff interesting, I wanna study chemistry now and learn to do acetylation of a certain product..
@@michaelwerkov3438 It's normal in China... you can also get something like benzaldehyde or HBr easily and legal, but something other are extremely hard to buy with a personal ID like diethyl ether, sulfuric acid or acetone lol
I probably let some kind of impurity collect in the receiving flask but a normal simple distillation should be good enough to purify it. Acetic anhydride boils at 140°C so you want to collect the distillate at that temperature.
@@allenhonaker4107 It really just matters on what you're distilling/heating. Substances like HCl, Bromine, Chromyl Chloride, etc. always want to find a way to escape its container. Those substances can eat away the silicone grease. Concentrated sulfuric acid is resistant against those substances and is used as a grease when distilling/heating those substances. If the substance isn't really as reactive as the substances I listed, you could just go ahead and use silicone grease. You can correct me if I am wrong.
I had an explosive reaction between manganese heptoxide and silicone grease, surprised the f*** out of me .., I previously thought of silicone grease as mainly inert ...
The cheapest and easiest way I know as of now is the reaction of sulfur monochloride and anhydrous sodium acetate. This is a video showing the method: ruclips.net/video/OrZ5Oa9K1R0/видео.html&ab_channel=LabCoatz . Sulfur chlorides are nasty and dangerous compounds so you should only attempt doing that method if you have proper precautions and safety.
Acetic anhydride is basically just 2 acetic acid molecules bonded together and all the water molecules are removed. It wouldn't make any sense if you were to make an anhydride by adding water to the substance.
I don't know how to speak Spanish but I translated your comment and it didn't really help much. The translator said that you are making a video about Dr Stone? I'm planning to start the synthesis of the antibiotic(sulfanilamide) soon and the synthesis should be done by this year.
I use Google translate: yes, there is an anime dr stone and in one episode they make sulfanilamide, where they mix chlorosulfonic acid and acetanilide to make the antibiotic, and I'm going to make a video explaining how it would be done in reality life, but I didn't find anything on the internet and no video on youtube explaining how to do it
I definitely know about Dr Stone! It's my most favourite anime. There is actually a video series of a Japanese chemist synthesizing it from benzene. Here is the video of him doing the last step in the synthesis where he reacts chlorosulfonic acid and acetanilide: ruclips.net/video/0HgB54fmSeA/видео.html&ab_channel=レイユール It might be very hard to understand the reaction as he is speaking in Japanese so I will also send a link to a image which shows all the steps of the synthesis: media.cheggcdn.com/study/0db/0db3b7c0-251e-4791-bf36-144986d55189/13112-21.2-2EEI1.png
Acetic anhydride is no precursor to heroin. It is used to acetylate morphine into heroin. The precursor is morphine and not acetic anhydride. A precursor is a substance that can easily be converted into another without having to go through a complete synthesis. I would love to see how you convert acetic anhydride into heroin without using morphine. 😳🤪
@@kemalk-gt7cusulfur chlorides and sodium acetate is another route but sulfur chlorides smell ungodly bad. The 2 step method he's referring to is likely a ketene lamp, but ketene is insanely toxic.
@@EddieTheH sure you can acetylate anthranillic acid to make methaqualone and also you can use it with phenylacetic acid and a touch of stinky pyridine to make phenyl 2 proponone that makes almost exclusively German marching powder . It burns aswell but I wouldn’t advise using it to cook food with bit stingy on the eye!
When I looked awhile ago I couldn't figure out how to make acetic anhydride, but now you open some new synthesis pathways for me. Thank you!
Glad I could help!
... you could get acetyl chloride but not acetic anydride?
@@michaelwerkov3438 The anhydride is hard to get since it's used to synthesize heroin.. In small amounts it'd be in something like aspirin synthesizing kits i believe. But you can have similar results or just a little less potent with just acetic acid & some catalyst I believe. There's also a plant that you can make the anhydride of, perhaps all of it is made from plants. I find this stuff interesting, I wanna study chemistry now and learn to do acetylation of a certain product..
@@michaelwerkov3438 It's normal in China... you can also get something like benzaldehyde or HBr easily and legal, but something other are extremely hard to buy with a personal ID like diethyl ether, sulfuric acid or acetone lol
@@bekeneelthe catalyst is sulfuric acid
Dam I'm definitely on the watchlist after coming here .......
Now I got to figure out how to make acetal chloride...
The sulphur chloride route might be easier for you. Simply dry distill a TCCA and sulphur mixture.
Acetonitrile and acetic acid and hydrogen chloride gas is the most otc route to acetyl chloride
@@nicholaschristodoulou5766 ok, now how to make acetonitrile
How about acetonitrile and acetic acidand hydrogen chloride gas to make acetyl chloride then react with sodium acetate to get acetic anhydride
Damn, i just wish i could get acetyl chloride....
Acetyl chloride is prohibited too
hey Brother Can we Use Fractional distillation instead of Simple distillation for Better Purity?
Why your acetic anhydride got yellow is there a way to make it crystal clear?
I probably let some kind of impurity collect in the receiving flask but a normal simple distillation should be good enough to purify it. Acetic anhydride boils at 140°C so you want to collect the distillate at that temperature.
Nice dog :)
for a moment I though it was a cat !
The cat is heading out
Where did you get your chemicals for this experiment?
I got the anhydrous sodium acetate online and the acetyl chloride was from a local chem supplier that helps me with ordering chemicals from China.
Could I use silicone grease to grease the joints? If not please explain why not and when and why it is necessary to use acid as opposed to silicone.
@@c2n10 that's what I usually do. I was was just wondering if one was preferable or necessary in some experiments as opposed to others
@@allenhonaker4107 It really just matters on what you're distilling/heating. Substances like HCl, Bromine, Chromyl Chloride, etc. always want to find a way to escape its container. Those substances can eat away the silicone grease. Concentrated sulfuric acid is resistant against those substances and is used as a grease when distilling/heating those substances. If the substance isn't really as reactive as the substances I listed, you could just go ahead and use silicone grease. You can correct me if I am wrong.
@@frostchem Thanks. That's exactly what I wanted to know. Now I'll be much more careful with what I use.😀
I had an explosive reaction between manganese heptoxide and silicone grease, surprised the f*** out of me .., I previously thought of silicone grease as mainly inert ...
@@petevenuti7355 wtf were you doing with manganese heptoxide in glass lol
Isn't acetic anhydride formed spontaneously by adding acetic acid to something? easier way
No, but I wish it was that easy lol.
@@frostchem What is the easiest and cheapest way?
@@frostchem I've heard that acetic anhydride is formed when acetic acid reacts with moisture in the air.
The cheapest and easiest way I know as of now is the reaction of sulfur monochloride and anhydrous sodium acetate. This is a video showing the method: ruclips.net/video/OrZ5Oa9K1R0/видео.html&ab_channel=LabCoatz . Sulfur chlorides are nasty and dangerous compounds so you should only attempt doing that method if you have proper precautions and safety.
Acetic anhydride is basically just 2 acetic acid molecules bonded together and all the water molecules are removed. It wouldn't make any sense if you were to make an anhydride by adding water to the substance.
Y para cuando el antibiótico? Quiero hacer un vídeo sobre dr stone
I don't know how to speak Spanish but I translated your comment and it didn't really help much. The translator said that you are making a video about Dr Stone? I'm planning to start the synthesis of the antibiotic(sulfanilamide) soon and the synthesis should be done by this year.
I use Google translate: yes, there is an anime dr stone and in one episode they make sulfanilamide, where they mix chlorosulfonic acid and acetanilide to make the antibiotic, and I'm going to make a video explaining how it would be done in reality life, but I didn't find anything on the internet and no video on youtube explaining how to do it
I definitely know about Dr Stone! It's my most favourite anime. There is actually a video series of a Japanese chemist synthesizing it from benzene. Here is the video of him doing the last step in the synthesis where he reacts chlorosulfonic acid and acetanilide: ruclips.net/video/0HgB54fmSeA/видео.html&ab_channel=レイユール
It might be very hard to understand the reaction as he is speaking in Japanese so
I will also send a link to a image which shows all the steps of the synthesis: media.cheggcdn.com/study/0db/0db3b7c0-251e-4791-bf36-144986d55189/13112-21.2-2EEI1.png
Acetic anhydride is no precursor to heroin. It is used to acetylate morphine into heroin. The precursor is morphine and not acetic anhydride. A precursor is a substance that can easily be converted into another without having to go through a complete synthesis. I would love to see how you convert acetic anhydride into heroin without using morphine. 😳🤪
Under the law it's considered a precursor
No, a "precursor" is any reagent used to make the final product. Nothing to do with not having to go through a complete synthesis. 🤦
Know it alls that know nothing
@yourmomurmom69 depends what country you’re in
The police sure as hell would say otherwise and their opinion is kinda more important than yours
Was it anhydrous acetic anhydride? Or is that redundant ?
It's anhydrous acetic anhydride.
@@frostchem is acetic anhydride always anhydrous or can you also make hydrated acetic anhydride?
Acetic anhydride is always anhydrous because if it gets in contact with water, it hydrolyses into acetic acid.
@@garrysekelli6776 to be fair i thought the Anhydride part gave that away
Turksh translate plz
Everybody's aware there is a MUCH easier way to do this yeah? 2 steps instead of 10.
How
Can you tell me the easy way, I think it's a lie
@@kemalk-gt7cusulfur chlorides and sodium acetate is another route but sulfur chlorides smell ungodly bad. The 2 step method he's referring to is likely a ketene lamp, but ketene is insanely toxic.
@@chemistryofquestionablequa6252 ketene Lol !!!!! If suicide is what your after
Yes please il have 5 litres please !! What 15mls!!!! Yer gona be making alot of smack with that!!!
You are aware that it has a multitude of more common uses than acetylating morphine? Also, 15mls will make quite a bit of smack.
@@EddieTheH sure you can acetylate anthranillic acid to make methaqualone and also you can use it with phenylacetic acid and a touch of stinky pyridine to make phenyl 2 proponone that makes almost exclusively German marching powder . It burns aswell but I wouldn’t advise using it to cook food with bit stingy on the eye!
Way to much h2so4 on that ground joint! Way to contaminate product!
How are you getting H2SO4 to distill at 140°C???
I believe the acid is placed there to catch any water and make a seal at the joint